Sunny O Abarikwu

Summary

Publications

  1. doi Kolaviron, a natural flavonoid from the seeds of Garcinia kola, reduces LPS-induced inflammation in macrophages by combined inhibition of IL-6 secretion, and inflammatory transcription factors, ERK1/2, NF-κB, p38, Akt, p-c-JUN and JNK
    Sunny O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria Electronic address
    Biochim Biophys Acta 1840:2373-81. 2014
  2. ncbi Causes and risk factors for male-factor infertility in Nigeria: a review
    Sunny O Abarikwu
    Department of Chemical Sciences, Redeemer s University, Redemption Camp, Ogun State Nigeria
    Afr J Reprod Health 17:150-66. 2013
  3. doi Rutin- and selenium-attenuated cadmium-induced testicular pathophysiology in rats
    S O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    Hum Exp Toxicol 32:395-406. 2013
  4. doi Effects of quercetin on mRNA expression of steroidogenesis genes in primary cultures of Leydig cells treated with atrazine
    Sunny O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    Toxicol In Vitro 27:700-7. 2013
  5. doi 4-Hydroxynonenal induces mitochondrial-mediated apoptosis and oxidative stress in SH-SY5Y human neuronal cells
    Sunny O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    Basic Clin Pharmacol Toxicol 110:441-8. 2012
  6. doi Quercetin decreases steroidogenic enzyme activity, NF-κB expression, and oxidative stress in cultured Leydig cells exposed to atrazine
    Sunny O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    Mol Cell Biochem 373:19-28. 2013
  7. doi Dietary antioxidant, quercetin, protects sertoli-germ cell coculture from atrazine-induced oxidative damage
    Sunny O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    J Biochem Mol Toxicol 26:477-85. 2012
  8. doi The protective effects of quercetin on the cytotoxicity of atrazine on rat Sertoli-germ cell co-culture
    S O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    Int J Androl 35:590-600. 2012
  9. doi Kolaviron biflavanoids of Garcinia kola seeds protect atrazine-induced cytotoxicity in primary cultures of rat Leydig cells
    Sunny O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    Int J Toxicol 31:407-15. 2012
  10. doi Kolaviron protects apoptotic cell death in PC12 cells exposed to atrazine
    Sunny O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    Free Radic Res 45:1061-73. 2011

Detail Information

Publications10

  1. doi Kolaviron, a natural flavonoid from the seeds of Garcinia kola, reduces LPS-induced inflammation in macrophages by combined inhibition of IL-6 secretion, and inflammatory transcription factors, ERK1/2, NF-κB, p38, Akt, p-c-JUN and JNK
    Sunny O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria Electronic address
    Biochim Biophys Acta 1840:2373-81. 2014
    ..Kolaviron (Kol-v), an important component of Garcinia kola seed has a variety of biologic activities, including anti-inflammatory properties...
  2. ncbi Causes and risk factors for male-factor infertility in Nigeria: a review
    Sunny O Abarikwu
    Department of Chemical Sciences, Redeemer s University, Redemption Camp, Ogun State Nigeria
    Afr J Reprod Health 17:150-66. 2013
    ..In this article, we analyze data from different sources and present evidence of the possible etiology and risk factors for male-factor infertility in Nigeria...
  3. doi Rutin- and selenium-attenuated cadmium-induced testicular pathophysiology in rats
    S O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    Hum Exp Toxicol 32:395-406. 2013
    ..These results suggest that both RUT and Se do not have synergistic role against Cd-induced testicular injury...
  4. doi Effects of quercetin on mRNA expression of steroidogenesis genes in primary cultures of Leydig cells treated with atrazine
    Sunny O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    Toxicol In Vitro 27:700-7. 2013
    ..These findings suggest that ATZ may stimulate the expression of tested steroidogenesis genes in ILCs via a mechanism independent of cyclic-AMP which was partially antagonize by QT...
  5. doi 4-Hydroxynonenal induces mitochondrial-mediated apoptosis and oxidative stress in SH-SY5Y human neuronal cells
    Sunny O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    Basic Clin Pharmacol Toxicol 110:441-8. 2012
    ..Oxidative stress may be involved in the initial priming of SH-SY5Y cells to 4-HNE-induced cytotoxicity in vitro...
  6. doi Quercetin decreases steroidogenic enzyme activity, NF-κB expression, and oxidative stress in cultured Leydig cells exposed to atrazine
    Sunny O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    Mol Cell Biochem 373:19-28. 2013
    ..These data showed that QT protected against ATZ-induced ILCs toxicity by restoring the expression of NF-κB and steroidogenic activity and by preventing the oxidative stress...
  7. doi Dietary antioxidant, quercetin, protects sertoli-germ cell coculture from atrazine-induced oxidative damage
    Sunny O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    J Biochem Mol Toxicol 26:477-85. 2012
    ..QT has protective effect against ATZ-induced oxidative stress through a reduction in ROS levels and lipid peroxidation...
  8. doi The protective effects of quercetin on the cytotoxicity of atrazine on rat Sertoli-germ cell co-culture
    S O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    Int J Androl 35:590-600. 2012
    ..QT might block these molecular events-induced by ATZ thereby protecting testicular Sertoli-germ cells from ATZ-induced toxicity...
  9. doi Kolaviron biflavanoids of Garcinia kola seeds protect atrazine-induced cytotoxicity in primary cultures of rat Leydig cells
    Sunny O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    Int J Toxicol 31:407-15. 2012
    ..Taken together, these findings indicate that Kol protects ILCs from ATZ-induced toxicity via the reduction in ROS and MDA levels and induce normalization of mRNA levels of all the tested genes...
  10. doi Kolaviron protects apoptotic cell death in PC12 cells exposed to atrazine
    Sunny O Abarikwu
    Department of Chemical Sciences, College of Natural Sciences, Redeemer s University, Redemption City, Ogun State, Nigeria
    Free Radic Res 45:1061-73. 2011
    ..Together, these data suggest that KV has the therapeutic potential against chemical-induced apoptotic cell death in the neuronal system...