Essam Abdel-Sattar

Summary

Publications

  1. doi request reprint Acylated pregnane glycosides from Caralluma tuberculata and their antiparasitic activity
    Essam Abdel-Sattar
    Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia
    Phytochemistry 69:2180-6. 2008
  2. doi request reprint Russelioside B, a pregnane glycoside ameliorates hyperglycemia in streptozotocin induced diabetic rats by regulating key enzymes of glucose metabolism
    Essam Abdel-Sattar
    Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt Electronic address
    Chem Biol Interact 252:47-53. 2016
  3. doi request reprint Screening of immunomodulatory activity of total and protein extracts of some Moroccan medicinal plants
    Abdeljlil Daoudi
    Bioactive Molecules Laboratory, Immunology and Pharmacology Unit, Faculty of Science and Technology, Fez, Morocco
    Toxicol Ind Health 29:245-53. 2013
  4. doi request reprint Antihyperglycemic activity of Caralluma tuberculata in streptozotocin-induced diabetic rats
    Essam A Abdel-Sattar
    Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia
    Food Chem Toxicol 59:111-7. 2013
  5. pmc Anti-inflammatory and antiproliferative activities of date palm pollen (Phoenix dactylifera) on experimentally-induced atypical prostatic hyperplasia in rats
    Ahmed A Elberry
    Department of Clinical Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia
    J Inflamm (Lond) 8:40. 2011
  6. ncbi request reprint Chemical and biological investigation of Araucaria heterophylla Salisb. resin
    Essam Abdel-Sattar
    Department of Natural Products, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Kingdom of Saudi Arabia
    Z Naturforsch C 64:819-23. 2009
  7. doi request reprint Antihyperglycaemic and hypolipidaemic effects of the methanolic extract of Caralluma tuberculata in streptozotocin-induced diabetic rats
    Essam Abdel-Sattar
    Department of Natural Products, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia
    Nat Prod Res 25:1171-9. 2011
  8. doi request reprint In vitro activities of plant extracts from Saudi Arabia against malaria, leishmaniasis, sleeping sickness and Chagas disease
    Essam Abdel-Sattar
    Department of Natural Products, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia
    Phytother Res 24:1322-8. 2010
  9. doi request reprint New sulphide derivative from Ferula rutabensis
    Essam Abdel-Sattar
    Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
    Nat Prod Res 23:861-5. 2009
  10. doi request reprint Antitrypanosomal activity of some pregnane glycosides isolated from Caralluma species
    Essam Abdel-Sattar
    Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia
    Phytomedicine 16:659-64. 2009

Collaborators

Detail Information

Publications24

  1. doi request reprint Acylated pregnane glycosides from Caralluma tuberculata and their antiparasitic activity
    Essam Abdel-Sattar
    Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia
    Phytochemistry 69:2180-6. 2008
    ..All the isolated compounds were tested for their antimalarial and antitrypanosomal activities as well as their cytotoxicity against human diploid embryonic cell line (MRC5)...
  2. doi request reprint Russelioside B, a pregnane glycoside ameliorates hyperglycemia in streptozotocin induced diabetic rats by regulating key enzymes of glucose metabolism
    Essam Abdel-Sattar
    Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt Electronic address
    Chem Biol Interact 252:47-53. 2016
    ..Hence, administration of russelioside B may represent a potentially useful strategy for the management of diabetes. ..
  3. doi request reprint Screening of immunomodulatory activity of total and protein extracts of some Moroccan medicinal plants
    Abdeljlil Daoudi
    Bioactive Molecules Laboratory, Immunology and Pharmacology Unit, Faculty of Science and Technology, Fez, Morocco
    Toxicol Ind Health 29:245-53. 2013
    ..The results of this study may also have implications in therapeutic treatment of infections, such as prophylactic and adjuvant with cancer chemotherapy...
  4. doi request reprint Antihyperglycemic activity of Caralluma tuberculata in streptozotocin-induced diabetic rats
    Essam A Abdel-Sattar
    Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia
    Food Chem Toxicol 59:111-7. 2013
    ..ME was standardized through LC-MS analysis for its major pregnanes. ..
  5. pmc Anti-inflammatory and antiproliferative activities of date palm pollen (Phoenix dactylifera) on experimentally-induced atypical prostatic hyperplasia in rats
    Ahmed A Elberry
    Department of Clinical Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia
    J Inflamm (Lond) 8:40. 2011
    ..Suspension of date palm pollen (DPP) is an herbal mixture that is widely used in folk medicine for male infertility. The aim of the present study was to evaluate the effect of DPP suspension and extract on APH-induced rats...
  6. ncbi request reprint Chemical and biological investigation of Araucaria heterophylla Salisb. resin
    Essam Abdel-Sattar
    Department of Natural Products, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Kingdom of Saudi Arabia
    Z Naturforsch C 64:819-23. 2009
    ..In addition, the resin and the isolated compounds showed variable cytotoxic activities against breast (MCF7) and colon (HCT116) cancer cell lines...
  7. doi request reprint Antihyperglycaemic and hypolipidaemic effects of the methanolic extract of Caralluma tuberculata in streptozotocin-induced diabetic rats
    Essam Abdel-Sattar
    Department of Natural Products, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia
    Nat Prod Res 25:1171-9. 2011
    ..tuberculata has both antihyperglycaemic and hypolipidaemic effects in STZ-induced diabetic rats that may need further studies to be used in the management of diabetes and associated hyperlipedaemia...
  8. doi request reprint In vitro activities of plant extracts from Saudi Arabia against malaria, leishmaniasis, sleeping sickness and Chagas disease
    Essam Abdel-Sattar
    Department of Natural Products, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia
    Phytother Res 24:1322-8. 2010
    ..falciparum (IC(50) 0.65 microg/mL; MRC-5 CC(50) > 30 microg /mL). These three extracts will be subjected for further extensive studies to isolate and identify their active constituents...
  9. doi request reprint New sulphide derivative from Ferula rutabensis
    Essam Abdel-Sattar
    Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
    Nat Prod Res 23:861-5. 2009
    ..Their characterisation was based on their spectral data, including MS, 1D- and 2D-NMR...
  10. doi request reprint Antitrypanosomal activity of some pregnane glycosides isolated from Caralluma species
    Essam Abdel-Sattar
    Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia
    Phytomedicine 16:659-64. 2009
    ..85 microg/ml), which exhibited the highest selectivity index (SI 12.04). It was noticed that acylation is required for the antitrypanosomal activity while glycosylation at C-20 has no significant effect on the activity...
  11. doi request reprint Chemical composition, insecticidal and insect repellent activity of Schinus molle L. leaf and fruit essential oils against Trogoderma granarium and Tribolium castaneum
    Essam Abdel-Sattar
    Department of Pharmacognosy, College of Pharmacy, University of Alexandria, Alexandria, Egypt
    Nat Prod Res 24:226-35. 2010
    ..84%, respectively. p-Cymene was identified as a major component in both oils. The high yield and efficacy of S. molle essential oil against T. granarium and T. castaneum suggest that it may provide leads for active insecticidal agents...
  12. doi request reprint Antiplasmodial and antitrypanosomal activity of plants from the Kingdom of Saudi Arabia
    Essam Abdel-Sattar
    Department of Natural Products, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
    J Nat Med 63:232-9. 2009
    ..9). The methanolic extracts of 34 plants showed good activity with score 2 (IC(50) < 12.5 and > 1.56 microg/ml), while the extracts of seven plants were inactive (IC(50) > 12.5 microg/ml, score 1)...
  13. ncbi request reprint Acylated pregnane glycosides from Caralluma russeliana
    Essam Abdel-Sattar
    Department of Natural Products, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia
    Phytochemistry 68:1459-63. 2007
    ..The structures of the compounds were elucidated using MS, 1H NMR, 13C NMR, 1H-1H COSY, HMQC, NOESY and HMBC experiments...
  14. doi request reprint Acylated pregnane glycosides from Caralluma quadrangula
    Hossam M Abdallah
    Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia
    Phytochemistry 88:54-60. 2013
    ..The isolated compounds were tested for their cytotoxic activity against breast cancer (MCF7) cell line...
  15. doi request reprint Iridoid glycosides from Barleria trispinosa
    Fathalla M H Harraz
    Faculty of Pharmacy, Department of Natural Products and Alternative Medicine, King Abdul Aziz University, Jeddah, Kingdom of Saudi Arabia
    Nat Prod Res 23:903-8. 2009
    ..The structures of the isolated compounds were elucidated by spectroscopic evidence, mainly one- and two-dimensional proton and carbon-13 NMR spectroscopy...
  16. ncbi request reprint New oxypregnane glycosides from Caralluma penicillata
    Essam Abdel-Sattar
    Department of Pharmacognosy, College of Pharmacy, Cairo University, Cairo, Egypt
    Planta Med 68:430-4. 2002
    ..E. Br. (Asclepiadaceae) yielded four new oxypregnane glycosides, penicillosides D-G. The structures of the isolated compounds were established by different spectroscopic methods...
  17. doi request reprint Acaricidal activity of Swietenia mahogani and Swietenia macrophylla ethanolic extracts against Varroa destructor in honeybee colonies
    Soheir M El Zalabani
    Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, Egypt
    Exp Parasitol 130:166-70. 2012
    ..This study suggested that the use of natural plant extracts or their products as ecofriendly biodegradable agents could be of high value for the control of Varroa mite...
  18. doi request reprint Antiprotozoal activity of major constituents from the bioactive fraction of Verbesina encelioides
    Shahira M Ezzat
    a Faculty of Pharmacy, Department of Pharmacognosy, Cairo University, Cairo, Egypt
    Nat Prod Res 31:676-680. 2017
    ..cruzi, while 5 and 6 were inactive against all tested protozoa. All compounds were non-cytotoxic. The isolated constituents showed less antiprotozoal activity than the crude fraction...
  19. doi request reprint HCV-NS3/4A protease inhibitory iridoid glucosides and dimeric foliamenthoic acid derivatives from Anarrhinum orientale
    Riham Salah El Dine
    Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt
    J Nat Prod 74:943-8. 2011
    ..A computational docking study of the isolated compounds against HCV protease was used to formulate a hypothetical mechanism for the inhibitory activity of the active compounds on the enzymes tested...
  20. doi request reprint Isolation of major phenolics from Launaea spinosa and their protective effect on HepG2 cells damaged with t-BHP
    Hossam Abdallah
    a Department of Natural Products, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia
    Pharm Biol 54:536-41. 2016
    ..Some Launaea species (Asteraceae) are used traditionally to treat liver oxidative stress...
  21. ncbi request reprint Phenylalkylamine alkaloids from Stapelia hirsuta L
    Marwan Shabana
    Department of Pharmacognosy, College of Pharmacy, Cairo University, Cairo 11562, Egypt
    Nat Prod Res 20:710-4. 2006
    ..The structures of the isolated alkaloids were determined as N-acetyl hordenine (a new natural compound), hordenine, candicine and hordenine-1-O-beta-D-glucoside, in addition to luteolin-7-O-beta-D-glucopyranoside...
  22. pmc Hepatoprotective Effect and Chemical Assessment of a Selected Egyptian Chickpea Cultivar
    Reham H Mekky
    Department of Pharmacognosy, Faculty of Pharmacy, Egyptian Russian University Cairo, Egypt
    Front Pharmacol 7:344. 2016
    ..This can be attributed, at least partly, to the antioxidant and anti-inflammatory activity of the isoflavones and phenolic acids content of the extract...
  23. doi request reprint A new triterpene and protective effect of Periploca somaliensis Browicz fruits against CClâ‚„-induced injury on human hepatoma cell line (Huh7)
    Azza R Abdel-Monem
    a Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt
    Nat Prod Res 29:423-9. 2015
    ..The structures of the isolated compounds were elucidated by the analysis of 1D and 2D NMR spectral data...
  24. ncbi request reprint Antioxidant and hepatoprotective effects of Eucalyptus maculata
    Abdel Fattah Mohamed
    Department of Pharmacology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt
    Med Sci Monit 11:BR426-31. 2005
    ....