Ijaz Ahmad

Summary

Publications

  1. ncbi request reprint Urease and serine protease inhibitory alkaloids from Isatis tinctoria
    Ijaz Ahmad
    Departemnt of Chemistry, Kohat University of Science and Technology, Kohat, N W F P, Pakistan
    J Enzyme Inhib Med Chem 23:918-21. 2008
  2. doi request reprint Xanthine oxidase/tyrosinase inhibiting, antioxidant, and antifungal oxindole alkaloids from Isatis costata
    Ijaz Ahmad
    Department of Chemistry, Kohat University of Science and Technology, Kohat, N W F P, Pakistan
    Pharm Biol 48:716-21. 2010
  3. doi request reprint Antioxidant phenylpropanoid glycosides from Buddleja davidii
    Ijaz Ahmad
    Department of Chemistry, Kohat University of Science and Technology, Kohat 26000, NWFP, Pakistan
    J Enzyme Inhib Med Chem 24:993-7. 2009
  4. ncbi request reprint Butyrylcholinesterase, lipoxygenase inhibiting and antifungal alkaloids from Isatis tinctoria
    Ijaz Ahmad
    Medicinal Botanic Centre, PCSIR Laboratories Complex, Peshawar, N W F P, Pakistan
    J Enzyme Inhib Med Chem 23:313-6. 2008
  5. ncbi request reprint Lipoxygenase inhibiting and antioxidant iridoids from Buddleja crispa
    Ijaz Ahmad
    Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing, China
    J Enzyme Inhib Med Chem 23:140-3. 2008
  6. doi request reprint Antioxidative iridoid glycosides from the sky flower (Duranta repens Linn)
    Fozia Ijaz
    KUST Institute of Medical Sciences, Kohat University of Science and Technology, Kohat, NWFP, Pakistan
    J Enzyme Inhib Med Chem 26:88-92. 2011
  7. doi request reprint Two new anti-plasmodial flavonoid glycosides from Duranta repens
    Fozia Ijaz
    Kohat Institute of Medical Sciences, Kohat University of Science and Technology, Kohat, N W F P, Pakistan
    J Enzyme Inhib Med Chem 25:773-8. 2010
  8. doi request reprint Effect of thiamine on lipid profile in diabetic rats
    Abdul Khaliq Naveed
    Department of Biochemistry and Molecular Biology, Army Medical College, Rawalpindi
    J Coll Physicians Surg Pak 19:165-8. 2009
  9. doi request reprint Detection of Mycobacterium avium subsp. paratuberculosis in tissue samples of cattle and buffaloes
    Farhan Anwar Khan
    Centre of Biological Production, Directorate of Veterinary Research Institute, NWFP, Peshawar, 25000, Pakistan
    Trop Anim Health Prod 42:633-8. 2010
  10. doi request reprint Repenins A-D, four new antioxidative coumarinolignoids from Duranta repens Linn
    Nisar Ahmad
    Department of Plant Sciences, Kohat University of Science and Technology, Kohat 26000, N W F P, Pakistan
    Bioorg Med Chem Lett 19:3521-4. 2009

Collaborators

  • Nisar Ahmad
  • Javid Hussain
  • Abdul Khaliq Naveed
  • Abdul Malik
  • Itrat Fatima
  • Fozia Ijaz
  • Nighat Afza
  • Sher Bahadar Khan
  • Azhar ul Haq
  • Farhan Anwar Khan
  • Munawar Hussain
  • Mehreen Latif
  • Lubna Iqbal
  • Itrat Anis
  • Sibao Chen
  • Naima Mumtaz
  • Shahid Khan
  • Muhammad Ijaz Ali
  • FangHai Wang
  • Zafar Iqbal Chaudhry
  • S M Shakil Hussain
  • Zaheer Ahmed
  • Ejaz Ahmed
  • Durey Nayab Zahra
  • - Azhar-Ul-Haq
  • Asma Ejaz
  • M Iqbal Choudhary
  • Shagufta Perveen

Detail Information

Publications18

  1. ncbi request reprint Urease and serine protease inhibitory alkaloids from Isatis tinctoria
    Ijaz Ahmad
    Departemnt of Chemistry, Kohat University of Science and Technology, Kohat, N W F P, Pakistan
    J Enzyme Inhib Med Chem 23:918-21. 2008
    ..31 microM against Bacillus pasteurii & Jack bean urease, respectively. Compounds 3 and 2 also showed potent inhibitory potential against alpha-chymotrypsin with IC(50) values of 23.40 +/- 0.21 and 27.45 +/- 0.23 microM, respectively...
  2. doi request reprint Xanthine oxidase/tyrosinase inhibiting, antioxidant, and antifungal oxindole alkaloids from Isatis costata
    Ijaz Ahmad
    Department of Chemistry, Kohat University of Science and Technology, Kohat, N W F P, Pakistan
    Pharm Biol 48:716-21. 2010
    ..The crude extract and compounds 1, 2, 5, and 6 showed significant antifungal activity against Trichophyton schoen leinii, Aspergillus niger, Candida albicans, Trichophyton simii, and Macrophomina phaseolina...
  3. doi request reprint Antioxidant phenylpropanoid glycosides from Buddleja davidii
    Ijaz Ahmad
    Department of Chemistry, Kohat University of Science and Technology, Kohat 26000, NWFP, Pakistan
    J Enzyme Inhib Med Chem 24:993-7. 2009
    ..Calceolarioside A (1) displayed the strongest scavenging potential with IC(50) values of (4.15 +/- 0.07, 40.32 +/- 0.09, 2.26 +/- 0.03 microM) for OH, total ROS and scavenging of ONOO(-), respectively...
  4. ncbi request reprint Butyrylcholinesterase, lipoxygenase inhibiting and antifungal alkaloids from Isatis tinctoria
    Ijaz Ahmad
    Medicinal Botanic Centre, PCSIR Laboratories Complex, Peshawar, N W F P, Pakistan
    J Enzyme Inhib Med Chem 23:313-6. 2008
    ..02 and 33.7 +/- 0.05 microM against LOX, respectively. The compounds (1-6) showed significant antifungal activity against Trichophyton schoen leinii, Aspergillus niger, Candida albicans, Trichophyton simii, and Macrophomina phaseolina...
  5. ncbi request reprint Lipoxygenase inhibiting and antioxidant iridoids from Buddleja crispa
    Ijaz Ahmad
    Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing, China
    J Enzyme Inhib Med Chem 23:140-3. 2008
    ..Compound 2 displayed significant inhibitory potential against enzyme lipoxygenase in a concentration-dependant fashion with IC(50) value of 39.7 +/- 0.02microM, along with DPPH radical scavenging activity with IC(50) value 0.638 mM...
  6. doi request reprint Antioxidative iridoid glycosides from the sky flower (Duranta repens Linn)
    Fozia Ijaz
    KUST Institute of Medical Sciences, Kohat University of Science and Technology, Kohat, NWFP, Pakistan
    J Enzyme Inhib Med Chem 26:88-92. 2011
    ..481 ± 0.06 mM, 4.07 ± 0.03, 43.30 ± 0.05, 3.39 ± 0.02 μM) for the DPPH radicals, ·OH inhibitory activity test, total ROS inhibitory activity test and the ONOO(-) scavenging activity test, respectively...
  7. doi request reprint Two new anti-plasmodial flavonoid glycosides from Duranta repens
    Fozia Ijaz
    Kohat Institute of Medical Sciences, Kohat University of Science and Technology, Kohat, N W F P, Pakistan
    J Enzyme Inhib Med Chem 25:773-8. 2010
    ..The compounds (1-7) showed potent anti-plasmodial activities against D6 and W2 strains of Plasmodium falciparum, with IC(50) values in the range of 5.2-13.5 μM and 5.9-13.1 μM, respectively...
  8. doi request reprint Effect of thiamine on lipid profile in diabetic rats
    Abdul Khaliq Naveed
    Department of Biochemistry and Molecular Biology, Army Medical College, Rawalpindi
    J Coll Physicians Surg Pak 19:165-8. 2009
    ..To determine the effect of high dose thiamine on dyslipidemia in diabetic rats...
  9. doi request reprint Detection of Mycobacterium avium subsp. paratuberculosis in tissue samples of cattle and buffaloes
    Farhan Anwar Khan
    Centre of Biological Production, Directorate of Veterinary Research Institute, NWFP, Peshawar, 25000, Pakistan
    Trop Anim Health Prod 42:633-8. 2010
    ..AFB were also detected in tissue scraping smears of these animals. It is concluded that infection by various mycobacterium species can be differentiated by PCR, which is not possible by acid-fast staining technique...
  10. doi request reprint Repenins A-D, four new antioxidative coumarinolignoids from Duranta repens Linn
    Nisar Ahmad
    Department of Plant Sciences, Kohat University of Science and Technology, Kohat 26000, N W F P, Pakistan
    Bioorg Med Chem Lett 19:3521-4. 2009
    ..The compounds (1-6) showed potent antioxidative scavenging activity against DPPH radicals, with IC(50) values in the range 0.420-0.625mM. Repenin B (2) displayed the strongest scavenging potential with IC(50) values of (0.420mM)...
  11. ncbi request reprint Isatinones A and B, new antifungal oxindole alkaloids from Isatis costata
    Itrat Fatima
    International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan
    Molecules 12:155-62. 2007
    ..Their structures have been assigned on the basis of spectroscopic techniques and chemical studies. Both new compounds showed significant antifungal activity...
  12. doi request reprint New butyrylcholinesterase inhibitory steroid and peroxy acid from Leucas urticifolia
    Itrat Fatima
    International Center for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan
    Arch Pharm Res 31:999-1003. 2008
    ..Their structures were elucidated on the basis of nuclear magnetic resonance (1D and 2D NMR) spectral data. Leucisterol showed potent inhibitory activity against butyrylcholinesterase enzyme...
  13. ncbi request reprint Isolation of onosmins A and B, lipoxygenase inhibitors from Onosma hispida
    Ijaz Ahmad
    International Center for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan
    Chem Pharm Bull (Tokyo) 53:907-10. 2005
    ..0 and 36.2 microM, respectively. Lineweaver-Burk as well as Dixon plots and their secondary replots indicated that the nature of inhibition was purely a non-competitive type, with K(i) values 22.0 microM and 31.1, respectively...
  14. ncbi request reprint Xanthine oxidase inhibiting flavonol glycoside from Amberboa ramosa
    Sher Bahadar Khan
    International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Pakistan
    Nat Prod Res 20:335-9. 2006
    ..The structures were deduced on the basis of 1D and 2D NMR techniques. The compounds 1-3 displayed weak to moderate inhibition against the xanthine oxidase enzyme...
  15. doi request reprint Structure determination of new steroids from Abutilon pakistanicum by NMR techniques
    Munawar Hussain
    International Center for Chemical and Biological Sciences, H E J Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan
    Magn Reson Chem 46:274-7. 2008
    ..Their structures have been assigned as 3-O-beta-D-glucopyranosyl-stigmasta-5,11(12)-diene (1) and 24beta-ethylcholesta-5, 9(11), 22E-trien-3beta-benzoate (2), respectively through extensive NMR studies...
  16. ncbi request reprint Two new protease-inhibiting glycosphingolipids from Buddleja crispa
    Ijaz Ahmad
    H E J Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan
    Chem Biodivers 4:917-24. 2007
    ..Their structures were elucidated by chemical and spectroscopic techniques. Both 1 and 2 showed significant inhibitory activity against alpha-chymotrypsin in a concentration-dependent manner...
  17. ncbi request reprint Leufolins A and B, potent butyrylcholinesterase-inhibiting flavonoid glucosides from Leucas urticifolia
    Itrat Fatima
    International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan
    Molecules 12:1447-54. 2007
    ..Their structures were elucidated on the basis of extensive analysis of nuclear magnetic resonance (1D and 2D NMR) spectral data. Both of these compounds exhibited significant inhibitory potential against the enzyme butyrylcholinesterase...
  18. ncbi request reprint Cholinesterase inhibitory constituents from Onosma hispida
    Ijaz Ahmad
    International Centre of Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Pakistan
    Chem Pharm Bull (Tokyo) 51:412-4. 2003
    ..In addition, (2S)-5,2'-dihydroxy-7,5'-dimethoxyflavanone (2), benzoic acid (3), and 4-hydroxy benzoic acid (4) are also reported for the first time from this species...