Hosea Akala

Summary

Publications

  1. doi request reprint Voulkensin C-E, new 11-oxocassane-type diterpenoids and a steroid glycoside from Caesalpinia volkensii stem bark and their antiplasmodial activities
    Charles O Ochieng
    Department of Chemistry, Maseno University, Private Bag, 40105 Maseno, Kenya
    Bioorg Med Chem Lett 23:3088-95. 2013
  2. doi request reprint Phytoecdysteroids from the stem bark of Vitex doniana and their anti-inflammatory effects
    Charles O Ochieng
    Department of Chemistry, Maseno University, Maseno, Kenya
    Planta Med 79:52-9. 2013
  3. doi request reprint Antinociceptive and antiplasmodial activities of cassane furanoditerpenes from Caesalpinia volkensii H. root bark
    Charles O Ochieng'
    Department of Chemistry, Maseno University, Private Bag, 40105, Maseno, Kenya
    Fitoterapia 83:74-80. 2012
  4. ncbi request reprint Antiplasmodial flavonoids from Erythrina sacleuxii
    Andrew W Andayi
    Department of Chemistry, University of Nairobi, Nairobi, Kenya
    Planta Med 72:187-9. 2006
  5. ncbi request reprint Antiplasmodial quinones from the rhizomes of Kniphofia foliosa
    Martha Induli
    Department of Chemistry, University of Nairobi, P O Box 30197 00100, Nairobi, Kenya
    Nat Prod Commun 8:1261-4. 2013
  6. ncbi request reprint Anti-plasmodial activities and X-ray crystal structures of rotenoids from Millettia usaramensis subspecies usaramensis
    Abiy Yenesew
    Department of Chemistry, University of Nairobi, PO Box 30197, Nairobi, Kenya
    Phytochemistry 64:773-9. 2003

Collaborators

  • Abiy Yenesew
  • Norman C Waters
  • Hellen A Oketch-Rabah
  • Charles O Ochieng
  • Philip O Owuor
  • Lawrence A O Manguro
  • Martha Induli
  • Ismail O Ishola
  • Charles O Ochieng'
  • Matthias Heydenreich
  • Andrew W Andayi
  • Sylvia Murunga
  • Keng Chong Wong
  • Sylvia A Opiyo
  • Robert Byamukama
  • Ermias Dagne
  • Meron Gebru
  • Negera Abdissa
  • Ingrid Wekesa
  • Lawrence A O Mang'uro
  • P Okinda Owuor
  • Martin G Peter
  • Peter M Gitu
  • Julia Wangui
  • Pamela Liyala
  • Solomon Derese
  • Jacob O Midiwo
  • Ogoche J Jondiko

Detail Information

Publications6

  1. doi request reprint Voulkensin C-E, new 11-oxocassane-type diterpenoids and a steroid glycoside from Caesalpinia volkensii stem bark and their antiplasmodial activities
    Charles O Ochieng
    Department of Chemistry, Maseno University, Private Bag, 40105 Maseno, Kenya
    Bioorg Med Chem Lett 23:3088-95. 2013
    ..88 and 2.74±1.10μM against D6 and W2 strains, respectively). These results suggest a possible contribution of phytochemicals from C. volkensii stem bark towards inhibition of plasmodial parasites' growth hence potential antimalarial...
  2. doi request reprint Phytoecdysteroids from the stem bark of Vitex doniana and their anti-inflammatory effects
    Charles O Ochieng
    Department of Chemistry, Maseno University, Maseno, Kenya
    Planta Med 79:52-9. 2013
    ..These results suggest a possible contribution of ecdysteroids to the anti-inflammatory effect of some V. doniana stem bark extracts...
  3. doi request reprint Antinociceptive and antiplasmodial activities of cassane furanoditerpenes from Caesalpinia volkensii H. root bark
    Charles O Ochieng'
    Department of Chemistry, Maseno University, Private Bag, 40105, Maseno, Kenya
    Fitoterapia 83:74-80. 2012
    ..05) low antiplasmodial activity. The phytochemical constituents from the root bark of C. volkensii had better analgesic properties than antimalarial properties, justifying the use of the plant root bark as a remedy for pain...
  4. ncbi request reprint Antiplasmodial flavonoids from Erythrina sacleuxii
    Andrew W Andayi
    Department of Chemistry, University of Nairobi, Nairobi, Kenya
    Planta Med 72:187-9. 2006
    ..Flavonoids and isoflavonoids isolated from the stem bark of E. sacleuxii were also tested and showed antiplasmodial activities. The structures were determined on the basis of spectroscopic evidence...
  5. ncbi request reprint Antiplasmodial quinones from the rhizomes of Kniphofia foliosa
    Martha Induli
    Department of Chemistry, University of Nairobi, P O Box 30197 00100, Nairobi, Kenya
    Nat Prod Commun 8:1261-4. 2013
    ..The new compound, 10-acetonylknipholone cyclooxanthrone, also showed anti-plasmodial activity. In an in vivo assay, knipholone anthrone displayed marginal antimalarial activity...
  6. ncbi request reprint Anti-plasmodial activities and X-ray crystal structures of rotenoids from Millettia usaramensis subspecies usaramensis
    Abiy Yenesew
    Department of Chemistry, University of Nairobi, PO Box 30197, Nairobi, Kenya
    Phytochemistry 64:773-9. 2003
    ..The structures were determined by spectroscopic analyses. CD and X-ray analyses established absolute configurations...