JorgeEduardo Toblli

Summary

Country: Argentina

Publications

  1. ncbi request reprint Iron(III)-hydroxide polymaltose complex in iron deficiency anemia / review and meta-analysis
    Jorge E Toblli
    Hospital Aleman, Laboratory of Experimental Medicine, Department of Internal Medicine, Buenos Aires, Argentina
    Arzneimittelforschung 57:431-8. 2007
  2. ncbi request reprint Morphological changes in cavernous tissue in spontaneously hypertensive rats
    J E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, and Instituto de Investigaciones Cardiológicas, Buenos Aires, Argentina
    Am J Hypertens 13:686-92. 2000
  3. ncbi request reprint Functional and morphological improvement in erectile tissue of hypertensive rats by long-term combined therapy with phosphodiesterase type 5 inhibitor and losartan
    Jorge Eduardo Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Buenos Aires
    J Sex Med 4:1291-303. 2007
  4. pmc Reduced cardiac expression of plasminogen activator inhibitor 1 and transforming growth factor beta1 in obese Zucker rats by perindopril
    J E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, CONICET, Av Pueyrredon 1640, Buenos Aires 1118, Argentina
    Heart 91:80-6. 2005
  5. ncbi request reprint NF-kappaB and chemokine-cytokine expression in renal tubulointerstitium in experimental hyperoxaluria. Role of the renin-angiotensin system
    Jorge Eduardo Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Av Pueyrredon 1640, Buenos Aires 1118, Argentina
    Urol Res 33:358-67. 2005
  6. ncbi request reprint Angiotensin-converting enzyme inhibition reduces lipid deposits in myocardium and improves left ventricular function of obese zucker rats
    Jorge Eduardo Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Consejo Nacional de Investigaciones Cientificas y Tecnicas, Buenos Aires, Argentina
    Obesity (Silver Spring) 14:1586-95. 2006
  7. ncbi request reprint The effect of different antihypertensive drugs on cavernous tissue in experimental chronic renal insufficiency
    Jorge E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Buenos Aires, Argentina
    J Nephrol 19:419-28. 2006
  8. ncbi request reprint Effects of ACE inhibition and beta-blockade on female genital structures in spontaneously hypertensive rats
    Jorge E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Consejo Nacional de Investigaciones Cientificas y Tecnicas CONICET, Buenos Aires, Argentina
    J Sex Med 4:1593-603. 2007
  9. ncbi request reprint Effects of ACE inhibition and beta-blockade on plasminogen activator inhibitor-1 and transforming growth factor-beta1 in carotid glomus and autonomic ganglia in hypertensive rats
    Jorge E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Buenos Aires, Argentina
    Am J Hypertens 20:326-34. 2007
  10. ncbi request reprint Protection of cavernous tissue in male spontaneously hypertensive rats. Beyond blood pressure control
    JorgeEduardo Toblli
    Laboratory of Experimental Medicine, Department of Internal Medicine, Hospital Aleman, Buenos Aires, Argentina
    Am J Hypertens 17:516-22. 2004

Collaborators

Detail Information

Publications33

  1. ncbi request reprint Iron(III)-hydroxide polymaltose complex in iron deficiency anemia / review and meta-analysis
    Jorge E Toblli
    Hospital Aleman, Laboratory of Experimental Medicine, Department of Internal Medicine, Buenos Aires, Argentina
    Arzneimittelforschung 57:431-8. 2007
    ..This probably reflects a better risk/benefit ratio of IPC in adults. Properly conducted randomized controlled trials, particularly in pediatrics, are needed...
  2. ncbi request reprint Morphological changes in cavernous tissue in spontaneously hypertensive rats
    J E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, and Instituto de Investigaciones Cardiológicas, Buenos Aires, Argentina
    Am J Hypertens 13:686-92. 2000
    ..Moreover, the increase in extracellular matrix expansion seems to affect not only the interstitium but also the neural structures of the penis...
  3. ncbi request reprint Functional and morphological improvement in erectile tissue of hypertensive rats by long-term combined therapy with phosphodiesterase type 5 inhibitor and losartan
    Jorge Eduardo Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Buenos Aires
    J Sex Med 4:1291-303. 2007
    ..Phosphodiesterase type 5 (PDE5) inhibitors and angiotensin II receptor blockers (ARB) are both common and efficient therapy in patients with ED and arterial hypertension, respectively...
  4. pmc Reduced cardiac expression of plasminogen activator inhibitor 1 and transforming growth factor beta1 in obese Zucker rats by perindopril
    J E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, CONICET, Av Pueyrredon 1640, Buenos Aires 1118, Argentina
    Heart 91:80-6. 2005
    ....
  5. ncbi request reprint NF-kappaB and chemokine-cytokine expression in renal tubulointerstitium in experimental hyperoxaluria. Role of the renin-angiotensin system
    Jorge Eduardo Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Av Pueyrredon 1640, Buenos Aires 1118, Argentina
    Urol Res 33:358-67. 2005
    ..This pathway seems to be mediated not only by AT1 but also by AT2 receptors of angiotensin II...
  6. ncbi request reprint Angiotensin-converting enzyme inhibition reduces lipid deposits in myocardium and improves left ventricular function of obese zucker rats
    Jorge Eduardo Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Consejo Nacional de Investigaciones Cientificas y Tecnicas, Buenos Aires, Argentina
    Obesity (Silver Spring) 14:1586-95. 2006
    ..The present study examined whether angiotensin-converting enzyme inhibition could ameliorate lipid deposition and ventricular function in the myocardium of obese Zucker rats (OZRs)...
  7. ncbi request reprint The effect of different antihypertensive drugs on cavernous tissue in experimental chronic renal insufficiency
    Jorge E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Buenos Aires, Argentina
    J Nephrol 19:419-28. 2006
    ....
  8. ncbi request reprint Effects of ACE inhibition and beta-blockade on female genital structures in spontaneously hypertensive rats
    Jorge E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Consejo Nacional de Investigaciones Cientificas y Tecnicas CONICET, Buenos Aires, Argentina
    J Sex Med 4:1593-603. 2007
    ..This study evaluated the possible differences between an angiotensin converting enzyme (ACE) inhibitor and a beta-blocker concerning their potential protective role on female external genitalia in spontaneously hypertensive rats (SHR)...
  9. ncbi request reprint Effects of ACE inhibition and beta-blockade on plasminogen activator inhibitor-1 and transforming growth factor-beta1 in carotid glomus and autonomic ganglia in hypertensive rats
    Jorge E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Buenos Aires, Argentina
    Am J Hypertens 20:326-34. 2007
    ....
  10. ncbi request reprint Protection of cavernous tissue in male spontaneously hypertensive rats. Beyond blood pressure control
    JorgeEduardo Toblli
    Laboratory of Experimental Medicine, Department of Internal Medicine, Hospital Aleman, Buenos Aires, Argentina
    Am J Hypertens 17:516-22. 2004
    ..We conclude that C provides a significant protective role against structural changes in vessels as well as in cavernous spaces of the erectile tissue, caused by arterial hypertension in SHR, beyond BP control...
  11. ncbi request reprint ACE inhibitor and angiotensin type I receptor antagonist in combination reduce renal damage in obese Zucker rats
    Jorge Eduardo Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, CONICET, Buenos Aires, Argentina
    Kidney Int 65:2343-59. 2004
    ....
  12. ncbi request reprint Potassium citrate administration ameliorates tubulointerstitial lesions in rats with uric acid nephropathy
    J E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Buenos Aires, Hospital Aleman, Argentina
    Clin Nephrol 55:59-68. 2001
    ..4, p < 0.05), when compared with the hyperuricemic group not treated with KCi (G1). These data suggest that KCi administration could provide a substantial benefit in the regard to tubulointerstitial lesion and progressive renal damage...
  13. ncbi request reprint Candesartan cilexetil protects cavernous tissue in spontaneously hypertensive rats
    J E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Buenos Aires, Argentina
    Int J Impot Res 16:305-12. 2004
    ..We conclude that candesartan cilexetil provides a significant protective role against morphologic changes in vessels as well as in cavernous spaces of the erectile tissue, caused by high blood pressure, in SHR...
  14. ncbi request reprint Enalapril prevents fatty liver in nephrotic rats
    Jorge Eduardo Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Buenos Aires, Argentina
    J Nephrol 15:358-67. 2002
    ..The purpose of the present study was to evaluate the possible protective action of an ACE inhibitor, enalapril (E), on fatty liver in adriamicyn-induced nephrotic rats (NR)...
  15. ncbi request reprint Angiotensin-converting enzyme inhibition and angiogenesis in myocardium of obese Zucker rats
    Jorge E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, CONICET, Av Pueyrredon 1640, Buenos Aires 1118, Argentina
    Am J Hypertens 17:172-80. 2004
    ....
  16. ncbi request reprint [Urinary calcium oxalate supersaturation beyond nephrolithiasis. Relationship with tubulointerstitial damage]
    Jorge E Toblli
    Laboratorio de Medicina Experimental, Hospital Aleman, Av Pueyrredon 1640, 1118 Buenos Aires, Argentina
    Medicina (B Aires) 63:97-104. 2003
    ..Considering these findings we think that urinary CaOx SS control rises in importance beyond nephrolithiasis...
  17. ncbi request reprint [Pulse wave velocity and urinary albumin excretion in hypertensive patients treated with perindopril]
    Jorge E Toblli
    Sección Hipertensión Arterial, Hospital Aleman, Av Pueyrredon 1640, 1118 Buenos Aires, Argentina
    Medicina (B Aires) 62:544-50. 2002
    ..These results suggest the existence of a real link between UAE and AC in non-smoking patients with arterial hypertension, and that ACE inhibition can similarly modify these two parameters...
  18. doi request reprint ACE inhibition and AT1 receptor blockade prevent fatty liver and fibrosis in obese Zucker rats
    Jorge E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina
    Obesity (Silver Spring) 16:770-6. 2008
    ....
  19. ncbi request reprint Cardiovascular protective role of a low-dose antihypertensive combination in obese Zucker rats
    Jorge E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, CONICET, Av Pueyrredon 1640, Buenos Aires 1118, Argentina
    J Hypertens 21:611-20. 2003
    ....
  20. ncbi request reprint Irbesartan restores the in-vivo insulin signaling pathway leading to Akt activation in obese Zucker rats
    Marina C Muñoz
    Instituto de Química y Fisicoquímica Biológicas UBA CONICET, Facultad de Farmacia y Bioquimica, Buenos Aires, Argentina
    J Hypertens 24:1607-17. 2006
    ....
  21. pmc Antifibrotic effects of pioglitazone on the kidney in a rat model of type 2 diabetes mellitus
    Jorge E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Buenos Aires, Argentina
    Nephrol Dial Transplant 24:2384-91. 2009
    ....
  22. ncbi request reprint Increased in vivo phosphorylation of insulin receptor at serine 994 in the liver of obese insulin-resistant Zucker rats
    Marcelo P Coba
    Instituto de Química y Fisicoquímica Biológicas UBA CONICET, Facultad de Farmacia y Bioquimica, Junin 956, C1113 AAD, Buenos Aires, Argentina
    J Endocrinol 182:433-44. 2004
    ..Our results suggest that Ser 994 is a novel in vivo IR phosphorylation site that might be involved in the regulation of the IRK in some states of insulin resistance...
  23. doi request reprint Comparative study of gastrointestinal tract and liver toxicity of ferrous sulfate, iron amino chelate and iron polymaltose complex in normal rats
    Jorge E Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Buenos Aires, Argentina
    Pharmacology 82:127-37. 2008
    ....
  24. doi request reprint Sodium load combined with low doses of exogenous angiotensin II upregulate intrarenal angiotensin II
    María Inés Rosón
    Department of Pathophysiology, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, INFIBIOC CONICET, Buenos Aires, Argentina
    Kidney Blood Press Res 32:334-41. 2009
    ..The present study was designed to evaluate the effects of a salt load combined with exogenous low nonhypertensive angiotensin II (Ang II) doses on Ang II intrarenal regulation...
  25. doi request reprint Angiotensin II increases intrarenal transforming growth factor-beta1 in rats submitted to sodium overload independently of blood pressure
    María I Rosón
    Department of Pathophysiology, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina
    Hypertens Res 31:707-15. 2008
    ..In conclusion, the interaction of Ang II with acute-sodium overload exacerbated intrarenal TGF-beta1, alpha-SMA and NF-kappaB expression, independently from changes in blood pressure levels, in normal rats...
  26. doi request reprint Different protective actions of losartan and tempol on the renal inflammatory response to acute sodium overload
    María I Rosón
    School of Pharmacy and Biochemistry, Department of Pathophysiology, Pharmacology and Clinical Biochemistry, University of Buenos Aires, INFIBIOC, CONICET, Buenos Aires, Argentina
    J Cell Physiol 224:41-8. 2010
    ..The protective role of tempol, but not of losartan, in the inflammatory response may be associated with its greater antioxidant effects...
  27. ncbi request reprint [High doses of aspirin reduce natriuresis in hypertensive patients treated with enalapril]
    Federico P Di Gennaro
    Departamento de Medicina Interna, Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno, Buenos Aires, Argentina
    Medicina (B Aires) 64:301-5. 2004
    ..These results suggest that in essential hypertensive individuals treated with enalapril and two ASA doses, low doses of ASA are associated with better blood pressure control and higher natriuresis...
  28. ncbi request reprint Renal protective role of atrial natriuretic peptide in acute sodium overload-induced inflammatory response
    María Inés Rosón
    Department of Pathophysiology, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina
    Am J Nephrol 26:590-601. 2006
    ..The present study was performed to explore the effect of exogenous infusions of atrial natriuretic peptide (ANP) on the early inflammatory response during acute sodium overload in normal rats...
  29. ncbi request reprint Intravenous iron reduces NT-pro-brain natriuretic peptide in anemic patients with chronic heart failure and renal insufficiency
    Jorge Eduardo Toblli
    Hospital Aleman, Buenos Aires, Argentina
    J Am Coll Cardiol 50:1657-65. 2007
    ....
  30. ncbi request reprint In vivo and in vitro effects of nebivolol on penile structures in hypertensive rats
    Jorge Eduardo Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Buenos Aires, Argentina
    Am J Hypertens 19:1226-32. 2006
    ..The aim of this study was to determine the functional and morphologic effects of nebivolol on penile structures in hypertensive rats...
  31. ncbi request reprint Different effect of losartan and amlodipine on penile structures in male spontaneously hypertensive rats
    Jorge Eduardo Toblli
    Laboratory of Experimental Medicine, Hospital Aleman, Buenos Aires, Argentina
    Am J Nephrol 24:614-23. 2004
    ....
  32. ncbi request reprint Effects of angiotensin II subtype 1 receptor blockade by losartan on tubulointerstitial lesions caused by hyperoxaluria
    Jorge Eduardo Toblli
    Laboratory of Experimental Medicine, Hospital Alemán and Instituto de Investigaciones Cardiológicas, Buenos Aires, Argentina
    J Urol 168:1550-5. 2002
    ..We evaluated whether angiotensin II type 1 receptor blockade prevents oxalate renal lesions...
  33. ncbi request reprint Differences between Candesartan and Hydralazine in the protection of penile structures in spontaneously hypertensive rats
    Osvaldo Néstor Mazza
    Laboratory of Experimental Medicine, Hospital Aleman, Buenos Aires, Argentina
    J Sex Med 3:604-11. 2006
    ..However, at present there is no substantial information concerning the functional aspect of this class of antihypertensive drugs...