Adam H Hart

Summary

Affiliation: The Walter and Eliza Hall Institute of Medical Research
Country: Australia

Publications

  1. pmc Enforced expression of the homeobox gene Mixl1 impairs hematopoietic differentiation and results in acute myeloid leukemia
    Stefan Glaser
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia
    Proc Natl Acad Sci U S A 103:16460-5. 2006
  2. ncbi Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo
    Adam H Hart
    The Walter and Eliza Hall Institute of Medical Research, P O Royal Melbourne Hospital, VIC 3050, Australia
    Development 129:3597-608. 2002
  3. ncbi Absence of suppressor of cytokine signalling 3 reduces self-renewal and promotes differentiation in murine embryonic stem cells
    Ariel Forrai
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia
    Stem Cells 24:604-14. 2006
  4. ncbi The pluripotency homeobox gene NANOG is expressed in human germ cell tumors
    Adam H Hart
    The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia
    Cancer 104:2092-8. 2005
  5. pmc Cancer and programmed cell death
    Ben Croker
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria 3050, Australia
    Genome Biol 4:318. 2003
  6. ncbi Identification, cloning and expression analysis of the pluripotency promoting Nanog genes in mouse and human
    Adam H Hart
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    Dev Dyn 230:187-98. 2004
  7. ncbi Transcriptional regulation of the homeobox gene Mixl1 by TGF-beta and FoxH1
    Adam H Hart
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade Parkville 3050, Vic, Australia
    Biochem Biophys Res Commun 333:1361-9. 2005
  8. ncbi Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
    Elgene Lim
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    Nat Med 15:907-13. 2009
  9. pmc Genome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental disease
    Georgina Caruana
    Department of Anatomy and Developmental Biology, Monash University, Clayton, Melbourne, Australia
    PLoS ONE 8:e55429. 2013
  10. ncbi Expression patterns and roles of periostin during kidney and ureter development
    Katrina Sorocos
    Department of Anatomy and Developmental Biology, School of Biomedical Sciences, Monash University, Melbourne, Victoria, Australia
    J Urol 186:1537-44. 2011

Collaborators

Detail Information

Publications10

  1. pmc Enforced expression of the homeobox gene Mixl1 impairs hematopoietic differentiation and results in acute myeloid leukemia
    Stefan Glaser
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia
    Proc Natl Acad Sci U S A 103:16460-5. 2006
    ..These observations establish a link between enforced Mixl1 expression and leukemogenesis in the mouse...
  2. ncbi Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo
    Adam H Hart
    The Walter and Eliza Hall Institute of Medical Research, P O Royal Melbourne Hospital, VIC 3050, Australia
    Development 129:3597-608. 2002
    ..Mixl1 is therefore required for the morphogenesis of axial mesoderm, the heart and the gut during embryogenesis...
  3. ncbi Absence of suppressor of cytokine signalling 3 reduces self-renewal and promotes differentiation in murine embryonic stem cells
    Ariel Forrai
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia
    Stem Cells 24:604-14. 2006
    ..Its absence perturbs the balance between activation of the JAK-STAT and SHP-2-ERK-1/2-MAPK pathways, resulting in less self-renewal and a greater potential for differentiation into the primitive endoderm lineage...
  4. ncbi The pluripotency homeobox gene NANOG is expressed in human germ cell tumors
    Adam H Hart
    The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia
    Cancer 104:2092-8. 2005
    ..Here we investigate the expression and gene copy number of NANOG in human germ cells and tumors of germ cell origin...
  5. pmc Cancer and programmed cell death
    Ben Croker
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria 3050, Australia
    Genome Biol 4:318. 2003
    ..A report on the 15th Lorne Cancer Conference, Lorne, Australia, 13-16 February 2003...
  6. ncbi Identification, cloning and expression analysis of the pluripotency promoting Nanog genes in mouse and human
    Adam H Hart
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    Dev Dyn 230:187-98. 2004
    ..The conservation in gene sequence, structure, and expression of mouse and human Nanog and Nanog2 genes may reflect a common role in the maintenance of pluripotency in both species...
  7. ncbi Transcriptional regulation of the homeobox gene Mixl1 by TGF-beta and FoxH1
    Adam H Hart
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade Parkville 3050, Vic, Australia
    Biochem Biophys Res Commun 333:1361-9. 2005
    ....
  8. ncbi Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
    Elgene Lim
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    Nat Med 15:907-13. 2009
    ..Our findings suggest that an aberrant luminal progenitor population is a target for transformation in BRCA1-associated basal tumors ...
  9. pmc Genome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental disease
    Georgina Caruana
    Department of Anatomy and Developmental Biology, Monash University, Clayton, Melbourne, Australia
    PLoS ONE 8:e55429. 2013
    ..To generate mouse models harbouring novel alleles that are involved in organogenesis we conducted a phenotype-driven, genome-wide mutagenesis screen in mice using the mutagen N-ethyl-N-nitrosourea (ENU)...
  10. ncbi Expression patterns and roles of periostin during kidney and ureter development
    Katrina Sorocos
    Department of Anatomy and Developmental Biology, School of Biomedical Sciences, Monash University, Melbourne, Victoria, Australia
    J Urol 186:1537-44. 2011
    ..We analyzed the temporal-spatial expression of periostin in the developing kidney and ureter as well as its roles in ureter branching morphogenesis, nephrogenesis and ureter development...