Mark Denham

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. pmc Glycogen synthase kinase 3β and activin/nodal inhibition in human embryonic stem cells induces a pre-neuroepithelial state that is required for specification to a floor plate cell lineage
    Mark Denham
    Centre for Neuroscience Research, Department of Anatomy and Neuroscience, University of Melbourne, Parkville, Australia
    Stem Cells 30:2400-11. 2012
  2. pmc Gli1 is an inducing factor in generating floor plate progenitor cells from human embryonic stem cells
    Mark Denham
    Centre for Neuroscience, University of Melbourne, Parkville, Australia
    Stem Cells 28:1805-15. 2010
  3. doi request reprint Transcriptional regulation and specification of neural stem cells
    Kimberly J Christie
    Department of Anatomy and Neuroscience, Centre for Neuroscience Research, Melbourne Brain Centre, Royal Parade, The University of Melbourne, Parkville, Melbourne, Vic, 3010, Australia
    Adv Exp Med Biol 786:129-55. 2013
  4. doi request reprint Neural differentiation of induced pluripotent stem cells
    Mark Denham
    Centre for Neuroscience, Department of Pharmacology, University of Melbourne, Parkville, Vic, Australia
    Methods Mol Biol 793:99-110. 2011
  5. pmc Neurons derived from human embryonic stem cells extend long-distance axonal projections through growth along host white matter tracts after intra-cerebral transplantation
    Mark Denham
    Centre for Neuroscience, University of Melbourne, Parkville, Vic, Australia
    Front Cell Neurosci 6:11. 2012
  6. doi request reprint Signals involved in neural differentiation of human embryonic stem cells
    Mark Denham
    Centre for Neuroscience, The University of Melbourne, Parkville, Vic, Australia
    Neurosignals 17:234-41. 2009
  7. pmc Multipotent caudal neural progenitors derived from human pluripotent stem cells that give rise to lineages of the central and peripheral nervous system
    Mark Denham
    Department of Anatomy and Neurosciences, University of Melbourne, Melbourne, Australia
    Stem Cells 33:1759-70. 2015
  8. doi request reprint Extracellular signal-regulated kinase 1/2 signaling promotes oligodendrocyte myelination in vitro
    Junhua Xiao
    Centre for Neuroscience Research, The University of Melbourne, Victoria, Australia
    J Neurochem 122:1167-80. 2012

Detail Information

Publications8

  1. pmc Glycogen synthase kinase 3β and activin/nodal inhibition in human embryonic stem cells induces a pre-neuroepithelial state that is required for specification to a floor plate cell lineage
    Mark Denham
    Centre for Neuroscience Research, Department of Anatomy and Neuroscience, University of Melbourne, Parkville, Australia
    Stem Cells 30:2400-11. 2012
    ....
  2. pmc Gli1 is an inducing factor in generating floor plate progenitor cells from human embryonic stem cells
    Mark Denham
    Centre for Neuroscience, University of Melbourne, Parkville, Australia
    Stem Cells 28:1805-15. 2010
    ..This study demonstrates that GLI1 is a determinant of FP specification in hESC and describes a highly robust and efficient in vitro model system that mimics the ventral neural tube organizer...
  3. doi request reprint Transcriptional regulation and specification of neural stem cells
    Kimberly J Christie
    Department of Anatomy and Neuroscience, Centre for Neuroscience Research, Melbourne Brain Centre, Royal Parade, The University of Melbourne, Parkville, Melbourne, Vic, 3010, Australia
    Adv Exp Med Biol 786:129-55. 2013
    ....
  4. doi request reprint Neural differentiation of induced pluripotent stem cells
    Mark Denham
    Centre for Neuroscience, Department of Pharmacology, University of Melbourne, Parkville, Vic, Australia
    Methods Mol Biol 793:99-110. 2011
    ....
  5. pmc Neurons derived from human embryonic stem cells extend long-distance axonal projections through growth along host white matter tracts after intra-cerebral transplantation
    Mark Denham
    Centre for Neuroscience, University of Melbourne, Parkville, Vic, Australia
    Front Cell Neurosci 6:11. 2012
    ..These findings illustrate the intrinsic capacity for neurons derived from human ES cells to integrate at a structural and functional level following transplantation...
  6. doi request reprint Signals involved in neural differentiation of human embryonic stem cells
    Mark Denham
    Centre for Neuroscience, The University of Melbourne, Parkville, Vic, Australia
    Neurosignals 17:234-41. 2009
    ..Understanding the signals involved in each of these stages is important for optimising methods to derive specific cell types for transplantation therapies, as well as for providing insight into the mechanisms of human neurogenesis...
  7. pmc Multipotent caudal neural progenitors derived from human pluripotent stem cells that give rise to lineages of the central and peripheral nervous system
    Mark Denham
    Department of Anatomy and Neurosciences, University of Melbourne, Melbourne, Australia
    Stem Cells 33:1759-70. 2015
    ..Our studies are the first to identify a multipotent neural progenitor derived from hPSCs, that is the precursor for major neural lineages of the embryonic caudal neural tube...
  8. doi request reprint Extracellular signal-regulated kinase 1/2 signaling promotes oligodendrocyte myelination in vitro
    Junhua Xiao
    Centre for Neuroscience Research, The University of Melbourne, Victoria, Australia
    J Neurochem 122:1167-80. 2012
    ..Collectively, these data identify that Erk1/2 signaling within oligodendrocytes exerts an important and direct effect to promote myelination...