A Barta

Summary

Affiliation: Medical University of Vienna
Country: Austria

Publications

  1. ncbi request reprint Plant SR proteins and their functions
    A Barta
    Max F Perutz Laboratories, Medical University of Vienna, Vienna, Austria
    Curr Top Microbiol Immunol 326:83-102. 2008
  2. pmc Identification of RNA targets for the nuclear multidomain cyclophilin atCyp59 and their effect on PPIase activity
    Olga Bannikova
    Max F Perutz Laboratories, Medical University of Vienna, Vienna, Austria
    Nucleic Acids Res 41:1783-96. 2013
  3. pmc Alternative splicing and nonsense-mediated decay modulate expression of important regulatory genes in Arabidopsis
    Maria Kalyna
    Max F Perutz Laboratories, Medical University of Vienna, Dr Bohr Gasse 9 3, A 1030 Vienna, Austria
    Nucleic Acids Res 40:2454-69. 2012
  4. pmc Implementing a rational and consistent nomenclature for serine/arginine-rich protein splicing factors (SR proteins) in plants
    Andrea Barta
    Max F Perutz Laboratories, Medical University of Viena, A 1030 Viena, Austria
    Plant Cell 22:2926-9. 2010
  5. pmc Evolutionary conservation and regulation of particular alternative splicing events in plant SR proteins
    Maria Kalyna
    Department of Medical Biochemistry, Max F Perutz Laboratories, Medical University of Vienna, Dr Bohr Gasse 9 3, A 1030 Vienna, Austria
    Nucleic Acids Res 34:4395-405. 2006
  6. pmc Use of fluorescent protein tags to study nuclear organization of the spliceosomal machinery in transiently transformed living plant cells
    Zdravko J Lorkovic
    Max F Perutz Laboratories, University Departments at the Vienna Biocenter, Institute of Medical Biochemistry, 1030 Vienna, Austria
    Mol Biol Cell 15:3233-43. 2004
  7. pmc Evolutionary conservation of minor U12-type spliceosome between plants and humans
    Zdravko J Lorkovic
    Max F Perutz Laboratories, University Departments at the Vienna Biocenter, Department of Biochemistry, Medical University of Vienna, A 1030 Vienna, Austria
    RNA 11:1095-107. 2005
  8. pmc Phosphoproteomics reveals extensive in vivo phosphorylation of Arabidopsis proteins involved in RNA metabolism
    Sergio de la Fuente van Bentem
    Department of Plant Molecular Biology, Max F Perutz Laboratories, University of Vienna, Dr Bohr Gasse 9, 1030 Vienna, Austria
    Nucleic Acids Res 34:3267-78. 2006
  9. pmc AtCyp59 is a multidomain cyclophilin from Arabidopsis thaliana that interacts with SR proteins and the C-terminal domain of the RNA polymerase II
    Monika Gullerova
    Max F Perutz Laboratories, University Departments at the Vienna Biocenter, Department of Biochemistry, Medical University of Vienna, Dr Bohrgasse 9 3, A 1030 Vienna, Austria
    RNA 12:631-43. 2006
  10. ncbi request reprint A novel family of plant splicing factors with a Zn knuckle motif: examination of RNA binding and splicing activities
    S Lopato
    Institut fur Biochemie, Universitat Wien, Vienna, Austria
    Plant Mol Biol 39:761-73. 1999

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Plant SR proteins and their functions
    A Barta
    Max F Perutz Laboratories, Medical University of Vienna, Vienna, Austria
    Curr Top Microbiol Immunol 326:83-102. 2008
    ..The tight regulation of splicing factors by alternative splicing might allow coordinated responses of their target genes...
  2. pmc Identification of RNA targets for the nuclear multidomain cyclophilin atCyp59 and their effect on PPIase activity
    Olga Bannikova
    Max F Perutz Laboratories, Medical University of Vienna, Vienna, Austria
    Nucleic Acids Res 41:1783-96. 2013
    ..Taken together, the available data suggest that these cyclophilins might have an important function in transcription regulation...
  3. pmc Alternative splicing and nonsense-mediated decay modulate expression of important regulatory genes in Arabidopsis
    Maria Kalyna
    Max F Perutz Laboratories, Medical University of Vienna, Dr Bohr Gasse 9 3, A 1030 Vienna, Austria
    Nucleic Acids Res 40:2454-69. 2012
    ..Finally, we have shown that AS/NMD regulates the abundance of transcripts of many genes important for plant development and adaptation including transcription factors, RNA processing factors and stress response genes...
  4. pmc Implementing a rational and consistent nomenclature for serine/arginine-rich protein splicing factors (SR proteins) in plants
    Andrea Barta
    Max F Perutz Laboratories, Medical University of Viena, A 1030 Viena, Austria
    Plant Cell 22:2926-9. 2010
    ....
  5. pmc Evolutionary conservation and regulation of particular alternative splicing events in plant SR proteins
    Maria Kalyna
    Department of Medical Biochemistry, Max F Perutz Laboratories, Medical University of Vienna, Dr Bohr Gasse 9 3, A 1030 Vienna, Austria
    Nucleic Acids Res 34:4395-405. 2006
    ..The evolutionary preservation of alternative splice forms together with highly conserved intron features argues for additional functions hidden in the genes of these plant-specific SR proteins...
  6. pmc Use of fluorescent protein tags to study nuclear organization of the spliceosomal machinery in transiently transformed living plant cells
    Zdravko J Lorkovic
    Max F Perutz Laboratories, University Departments at the Vienna Biocenter, Institute of Medical Biochemistry, 1030 Vienna, Austria
    Mol Biol Cell 15:3233-43. 2004
    ....
  7. pmc Evolutionary conservation of minor U12-type spliceosome between plants and humans
    Zdravko J Lorkovic
    Max F Perutz Laboratories, University Departments at the Vienna Biocenter, Department of Biochemistry, Medical University of Vienna, A 1030 Vienna, Austria
    RNA 11:1095-107. 2005
    ..Taken together, our data indicate that recognition and splicing of minor, AT-AC introns in plants is highly similar to that in humans...
  8. pmc Phosphoproteomics reveals extensive in vivo phosphorylation of Arabidopsis proteins involved in RNA metabolism
    Sergio de la Fuente van Bentem
    Department of Plant Molecular Biology, Max F Perutz Laboratories, University of Vienna, Dr Bohr Gasse 9, 1030 Vienna, Austria
    Nucleic Acids Res 34:3267-78. 2006
    ..These data suggest that the plant mRNA splicing machinery is a major target of phosphorylation and that a considerable number of proteins involved in RNA metabolism may be targeted by SRPKs...
  9. pmc AtCyp59 is a multidomain cyclophilin from Arabidopsis thaliana that interacts with SR proteins and the C-terminal domain of the RNA polymerase II
    Monika Gullerova
    Max F Perutz Laboratories, University Departments at the Vienna Biocenter, Department of Biochemistry, Medical University of Vienna, Dr Bohrgasse 9 3, A 1030 Vienna, Austria
    RNA 12:631-43. 2006
    ..Together our data suggest a possible function of AtCyp59 in activities connecting transcription and pre-mRNA processing. We discuss our data in the context of a dynamic interplay between transcription and pre-mRNA processing...
  10. ncbi request reprint A novel family of plant splicing factors with a Zn knuckle motif: examination of RNA binding and splicing activities
    S Lopato
    Institut fur Biochemie, Universitat Wien, Vienna, Austria
    Plant Mol Biol 39:761-73. 1999
    ..Taken together, these result show that atRSZp22 is a true plant splicing factor which combines structural and functional features of both h9G8 and hSRp20...
  11. ncbi request reprint Interactions of Arabidopsis RS domain containing cyclophilins with SR proteins and U1 and U11 small nuclear ribonucleoprotein-specific proteins suggest their involvement in pre-mRNA Splicing
    Zdravko J Lorkovic
    Max F Perutz Laboratories, University Departments at the Vienna Biocenter, Department of Biochemistry, Medical University of Vienna, Dr Bohrgasse 9 3, A 1030 Vienna, Austria
    J Biol Chem 279:33890-8. 2004
    ..Alternatively, binding of CypRS64 to proteins important for 5' splice site recognition suggests its involvement in the dynamics of spliceosome assembly...
  12. ncbi request reprint A plethora of plant serine/arginine-rich proteins: redundancy or evolution of novel gene functions?
    M Kalyna
    Max F Perutz Laboratories, University Department at the Vienna Biocenter, Department of Biochemistry, Medical University of Vienna, Dr Bohrgasse 9 3, A 1030 Vienna, Austria
    Biochem Soc Trans 32:561-4. 2004
    ..This might greatly influence gene expression of target genes as also exemplified by ectopic expression studies of particular SR proteins...
  13. pmc atSRp30, one of two SF2/ASF-like proteins from Arabidopsis thaliana, regulates splicing of specific plant genes
    S Lopato
    Institut fur Biochemie, Universitat Wien, Vienna Biocenter, A 1030 Vienna, Austria
    Genes Dev 13:987-1001. 1999
    ..The results of the structural and expression analyses of both genes suggest that atSRp34/SR1 acts as a general splicing factor, whereas atSRp30 functions as a specific splicing modulator...
  14. pmc Role of Cajal bodies and nucleolus in the maturation of the U1 snRNP in Arabidopsis
    Zdravko J Lorkovic
    Department of Medical Biochemistry, Max F Perutz Laboratories, Medical University of Vienna, Vienna, Austria
    PLoS ONE 3:e3989. 2008
    ..Therefore, it has been proposed that the final assembly of these spliceosomal snRNPs takes place in this nuclear compartment. In contrast, U1 snRNA in both animal and plant cells has rarely been found in this nuclear compartment...
  15. doi request reprint Co-localisation studies of Arabidopsis SR splicing factors reveal different types of speckles in plant cell nuclei
    Zdravko J Lorkovic
    Max F Perutz Laboratories, Medical University of Vienna, Department of Medical Biochemistry, Vienna, Austria
    Exp Cell Res 314:3175-86. 2008
    ....
  16. ncbi request reprint Compartmentalization of the splicing machinery in plant cell nuclei
    Zdravko J Lorkovic
    Max F Perutz Laboratories, University Departments at the Vienna Biocenter, Department of Biochemistry, Medical University of Vienna, Dr Bohrgasse 9 3, A 1030 Vienna, Austria
    Trends Plant Sci 9:565-8. 2004
    ..Recent studies on nuclear organization of splicing factors in plant cells provide insights into the compartmentalization of the plant cell nuclei and conservation of nuclear compartments between plants and metazoans...
  17. pmc Interaction of tetracycline with RNA: photoincorporation into ribosomal RNA of Escherichia coli
    R Oehler
    Institute of Biochemistry, University of Vienna, Vienna Biocenter, Dr Bohrgasse 9 3, A 1030 Vienna, Austria
    Nucleic Acids Res 25:1219-24. 1997
    ....
  18. doi request reprint Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis
    Sergio de la Fuente van Bentem
    Department of Plant Molecular Biology, Max F Perutz Laboratories, University of Vienna, Dr Bohr Gasse 9, 1030 Vienna, Austria
    J Proteome Res 7:2458-70. 2008
    ..Together, our data demonstrate that a combination of mass spectrometry with peptide chip phosphorylation profiling has a great potential to unravel phosphoproteome dynamics and to identify PK substrates...
  19. pmc Rct1, a nuclear RNA recognition motif-containing cyclophilin, regulates phosphorylation of the RNA polymerase II C-terminal domain
    Monika Gullerova
    Max F Perutz Laboratories, Medical University of Vienna, Department of Medical Biochemistry, Bohrgasse 9 3, A 1030 Vienna, Austria
    Mol Cell Biol 27:3601-11. 2007
    ..These data, together with the pleiotropic phenotype upon Rct1 deregulation, suggest that this multidomain cyclophilin is an important player in maintaining the correct phosphorylation code of the CTD and thereby regulating CTD function...
  20. ncbi request reprint Monitoring changes in alternative precursor messenger RNA splicing in multiple gene transcripts
    Craig G Simpson
    Genetics Programme, SCRI, Invergowrie, Dundee DD2 5DA, UK
    Plant J 53:1035-48. 2008
    ..It can readily be applied to much larger or targeted sets of gene transcripts to generate information on the significance and regulation of AS in plant growth and development, specific processes and responses to external stimuli...
  21. doi request reprint Alternative splicing in plants
    Craig G Simpson
    Genetics Programme, SCRI, Invergowrie, Dundee DD2 5DA, Scotland, UK
    Biochem Soc Trans 36:508-10. 2008
    ..Initial studies have identified new AS events confirming that current values for the frequency of AS in plants are likely to be underestimates...
  22. pmc Genome analysis: RNA recognition motif (RRM) and K homology (KH) domain RNA-binding proteins from the flowering plant Arabidopsis thaliana
    Zdravko J Lorkovic
    Institute of Medical Biochemistry, Vienna University, Dr Bohrgasse 9 3, 1030 Vienna, Austria
    Nucleic Acids Res 30:623-35. 2002
    ..This survey provides a first systematic analysis of plant RNA-binding proteins, which may serve as a basis for functional characterisation of this important protein group in plants...
  23. ncbi request reprint Network of interactions of a novel plant-specific Arg/Ser-rich protein, atRSZ33, with atSC35-like splicing factors
    Sergiy Lopato
    Institut für Medizinische Biochemie, Universitat Wien, Vienna Biocenter, Dr Bohrgasse 9 3, Wien A 1030, Austria
    J Biol Chem 277:39989-98. 2002
    ..However, the interacting domain is relatively small, allowing binding of additional proteins, a feature that is consistent with the proposed role of atRSZ33 in spliceosome assembly...
  24. ncbi request reprint Proto-oncoprotein TLS/FUS is associated to the nuclear matrix and complexed with splicing factors PTB, SRm160, and SR proteins
    Michael Meissner
    Institute of Cancer Research, Borschkegasse 8a, University of Vienna, A 1090 Vienna, Austria
    Exp Cell Res 283:184-95. 2003
    ..Coimmunolocalization confirmed the nuclear matrix association and interaction of TLS/FUS with PTB, SR proteins, and SRm160. Our results suggest that the matrix protein TLS/FUS plays a role in spliceosome assembly...
  25. pmc Ectopic expression of atRSZ33 reveals its function in splicing and causes pleiotropic changes in development
    Maria Kalyna
    Max F Perutz Laboratories, University Departments at the Vienna Biocenter, Institut für Med Biochemie, University of Vienna, A 1030 Vienna, Austria
    Mol Biol Cell 14:3565-77. 2003
    ..In addition, changes in activity of an auxin-responsive promoter suggest that auxin signaling is disturbed in these transgenic plants...