Irina S Druzhinina

Summary

Affiliation: Vienna University of Technology
Country: Austria

Publications

  1. pmc DNA barcoding survey of Trichoderma diversity in soil and litter of the Colombian lowland Amazonian rainforest reveals Trichoderma strigosellum sp. nov. and other species
    Carlos A López-Quintero
    CBS Fungal Biodiversity Centre CBS KNAW, Utrecht, The Netherlands
    Antonie Van Leeuwenhoek 104:657-74. 2013
  2. pmc Molecular phylogeny and species delimitation in the section Longibrachiatum of Trichoderma
    Irina S Druzhinina
    Research Area Biotechnology and Microbiology, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 166 5, A 1060 Vienna, Austria
    Fungal Genet Biol 49:358-68. 2012
  3. pmc Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma
    Christian P Kubicek
    Area Gene Technology and Applied Biochemistry, Institute of Chemical Engineering Vienna University of Technology, Getreidemarkt 9, 1060 Vienna, Austria
    Genome Biol 12:R40. 2011
  4. pmc Evolution and ecophysiology of the industrial producer Hypocrea jecorina (Anamorph Trichoderma reesei) and a new sympatric agamospecies related to it
    Irina S Druzhinina
    Research Area of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Vienna, Austria
    PLoS ONE 5:e9191. 2010
  5. doi request reprint Alternative reproductive strategies of Hypocrea orientalis and genetically close but clonal Trichoderma longibrachiatum, both capable of causing invasive mycoses of humans
    Irina S Druzhinina
    Research Area of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Vienna, Austria
    Microbiology 154:3447-59. 2008
  6. pmc The Trichoderma harzianum demon: complex speciation history resulting in coexistence of hypothetical biological species, recent agamospecies and numerous relict lineages
    Irina S Druzhinina
    Research Area of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 1665, A 1060 Vienna, Austria
    BMC Evol Biol 10:94. 2010
  7. ncbi request reprint An oligonucleotide barcode for species identification in Trichoderma and Hypocrea
    Irina S Druzhinina
    Division of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 1665, A 1060 Vienna, Austria
    Fungal Genet Biol 42:813-28. 2005
  8. pmc Global carbon utilization profiles of wild-type, mutant, and transformant strains of Hypocrea jecorina
    Irina S Druzhinina
    Research Area of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 1665, A 1060 Vienna, Austria
    Appl Environ Microbiol 72:2126-33. 2006
  9. ncbi request reprint Radioactive contamination of wild mushrooms: a cross-cultural risk perception study
    I Druzhinina
    Institute of Risk Research, University of Vienna, Türkenschanzstrasse 17 8, A 1180 Vienna, Austria
    J Environ Radioact 74:83-90. 2004
  10. pmc Purifying selection and birth-and-death evolution in the class II hydrophobin gene families of the ascomycete Trichoderma/Hypocrea
    Christian P Kubicek
    Research Area of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 1665, A 1060 Vienna, Austria
    BMC Evol Biol 8:4. 2008

Collaborators

Detail Information

Publications44

  1. pmc DNA barcoding survey of Trichoderma diversity in soil and litter of the Colombian lowland Amazonian rainforest reveals Trichoderma strigosellum sp. nov. and other species
    Carlos A López-Quintero
    CBS Fungal Biodiversity Centre CBS KNAW, Utrecht, The Netherlands
    Antonie Van Leeuwenhoek 104:657-74. 2013
    ..nov. Sequence similarity searches revealed that this species also occurs in soils of Malaysia and Cameroon, suggesting a pantropical distribution. ..
  2. pmc Molecular phylogeny and species delimitation in the section Longibrachiatum of Trichoderma
    Irina S Druzhinina
    Research Area Biotechnology and Microbiology, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 166 5, A 1060 Vienna, Austria
    Fungal Genet Biol 49:358-68. 2012
    ....
  3. pmc Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma
    Christian P Kubicek
    Area Gene Technology and Applied Biochemistry, Institute of Chemical Engineering Vienna University of Technology, Getreidemarkt 9, 1060 Vienna, Austria
    Genome Biol 12:R40. 2011
    ..Probably, the most studied biocontrol agents are species of the genus Hypocrea/Trichoderma...
  4. pmc Evolution and ecophysiology of the industrial producer Hypocrea jecorina (Anamorph Trichoderma reesei) and a new sympatric agamospecies related to it
    Irina S Druzhinina
    Research Area of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Vienna, Austria
    PLoS ONE 5:e9191. 2010
    ..It is believed to be an anamorph (asexual stage) of the common pantropical ascomycete Hypocrea jecorina...
  5. doi request reprint Alternative reproductive strategies of Hypocrea orientalis and genetically close but clonal Trichoderma longibrachiatum, both capable of causing invasive mycoses of humans
    Irina S Druzhinina
    Research Area of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Vienna, Austria
    Microbiology 154:3447-59. 2008
    ..longibrachiatum and H. orientalis suggests the danger of nosocomial infections by Hypocrea/Trichoderma and highlights the need for ecological studies of spore dispersal as source of invasive human mycoses...
  6. pmc The Trichoderma harzianum demon: complex speciation history resulting in coexistence of hypothetical biological species, recent agamospecies and numerous relict lineages
    Irina S Druzhinina
    Research Area of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 1665, A 1060 Vienna, Austria
    BMC Evol Biol 10:94. 2010
    ..Since recombination would be an important issue for the efficacy of an agent of the biological control in the field, we investigated the phylogenetic structure of the species...
  7. ncbi request reprint An oligonucleotide barcode for species identification in Trichoderma and Hypocrea
    Irina S Druzhinina
    Division of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 1665, A 1060 Vienna, Austria
    Fungal Genet Biol 42:813-28. 2005
    ..We conclude that oligonucleotide barcode is a powerful tool for the routine identification of Hypocrea/Trichoderma species and should be useful as a complement to traditional methods...
  8. pmc Global carbon utilization profiles of wild-type, mutant, and transformant strains of Hypocrea jecorina
    Irina S Druzhinina
    Research Area of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 1665, A 1060 Vienna, Austria
    Appl Environ Microbiol 72:2126-33. 2006
    ....
  9. ncbi request reprint Radioactive contamination of wild mushrooms: a cross-cultural risk perception study
    I Druzhinina
    Institute of Risk Research, University of Vienna, Türkenschanzstrasse 17 8, A 1180 Vienna, Austria
    J Environ Radioact 74:83-90. 2004
    ..Such discrepancies between professional and unprofessional opinions are discussed and some recommendations for risk communications are presented...
  10. pmc Purifying selection and birth-and-death evolution in the class II hydrophobin gene families of the ascomycete Trichoderma/Hypocrea
    Christian P Kubicek
    Research Area of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 1665, A 1060 Vienna, Austria
    BMC Evol Biol 8:4. 2008
    ..Based on their hydropathy patterns and solubility characteristics, hydrophobins are divided into two classes (I and II), the latter being found only in ascomycetes...
  11. ncbi request reprint Hypocrea crystalligena sp. nov., a common European species with a white-spored Trichoderma anamorph
    Walter M Jaklitsch
    Institute of Chemical Engineering, Research Area Gene Technology and Applied Biochemistry, Vienna University of Technology, Wien, Austria
    Mycologia 98:499-513. 2006
    ..crystalligena constitutes a separate evolutionary lineage with H. megalocitrina and H. psychrophila as its nearest neighbors. All these species form one phylogenetic clade with the H. pulvinata/H. citrina node...
  12. pmc Genetically closely related but phenotypically divergent Trichoderma species cause green mold disease in oyster mushroom farms worldwide
    Monika Komon-Zelazowska
    Research Area Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 1665, A 1060 Vienna, Austria
    Appl Environ Microbiol 73:7415-26. 2007
    ..A DNA BarCode for identification of these species based on ITS1 and ITS2 sequences has been provided and integrated in the main database for Hypocrea/Trichoderma (www.ISTH.info)...
  13. pmc The Hypocrea jecorina (Trichoderma reesei) hypercellulolytic mutant RUT C30 lacks a 85 kb (29 gene-encoding) region of the wild-type genome
    Verena Seidl
    Research Area Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 166 5, A 1060 Wien, Austria
    BMC Genomics 9:327. 2008
    ..To date this and an additional frame-shift mutation in the glycoprotein-processing beta-glucosidase II encoding gene are the only known genetic differences in strain RUT C30...
  14. pmc Clonal species Trichoderma parareesei sp. nov. likely resembles the ancestor of the cellulase producer Hypocrea jecorina/T. reesei
    Lea Atanasova
    Research Area of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 1665, A 1060 Vienna, Austria
    Appl Environ Microbiol 76:7259-67. 2010
    ..parareesei possesses a relatively high opportunistic potential, which probably ensured the survival of this species in ancient and sustainable environment such as tropical forests...
  15. pmc Fungal genus Hypocrea/Trichoderma: from barcodes to biodiversity
    Christian P Kubicek
    Institute of Chemical Engineering, Research Area Gene Technology and Applied Biochemistry, Vienna University of Technology, Getreidemarkt 9 E1665, A 1060 Vienna, Austria
    J Zhejiang Univ Sci B 9:753-63. 2008
    ....
  16. pmc Three European species of Hypocrea with reddish brown stromata and green ascospores
    Walter M Jaklitsch
    Faculty Centre for Systematic Botany, University of Vienna, Rennweg 14, A 1030 Vienna, Austria
    Mycologia 100:796-815. 2008
    ....
  17. pmc Impact of light on Hypocrea jecorina and the multiple cellular roles of ENVOY in this process
    Andre Schuster
    Division of Gene Technology and Applied Biochemistry, Institute for Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 1665, A 1060 Wien, Austria
    BMC Genomics 8:449. 2007
    ..Based on these data, we analyzed whether these genes are influenced by ENVOY and if overexpression of ENVOY in darkness would be sufficient to execute its function...
  18. pmc The putative protein methyltransferase LAE1 of Trichoderma atroviride is a key regulator of asexual development and mycoparasitism
    Razieh Karimi Aghcheh
    Microbiology Group, Research Division Biotechnology and Microbiology, Institute of Chemical Engineering, Vienna University of Technology, Vienna, Austria
    PLoS ONE 8:e67144. 2013
    ..Our study shows T. atroviride LAE1 is essential for asexual reproduction in the dark and for defense and parasitism on other fungi. ..
  19. pmc The CRE1 carbon catabolite repressor of the fungus Trichoderma reesei: a master regulator of carbon assimilation
    Thomas Portnoy
    Research Area Gene Technology and Applied Biochemistry, Institute of ChemicalEngineering, Technische Universitat Wien, Getreidemarkt, Vienna, Austria
    BMC Genomics 12:269. 2011
    ..In lower multicellular fungi, the C2H2 zinc finger CreA/CRE1 protein has been shown to act as the transcriptional repressor in this process. However, the complete list of its gene targets is not known...
  20. pmc Taxon-specific metagenomics of Trichoderma reveals a narrow community of opportunistic species that regulate each other's development
    Martina A Friedl
    Research Area of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 1665, A 1060 Vienna, Austria
    Microbiology 158:69-83. 2012
    ....
  21. doi request reprint Trichoderma: the genomics of opportunistic success
    Irina S Druzhinina
    Area Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Austria
    Nat Rev Microbiol 9:749-59. 2011
    ..with animals and plants may have evolved as a result of saprotrophy on fungal biomass (mycotrophy) and various forms of parasitism on other fungi (mycoparasitism), combined with broad environmental opportunism...
  22. doi request reprint Photostimulation of Hypocrea atroviridis growth occurs due to a cross-talk of carbon metabolism, blue light receptors and response to oxidative stress
    Martina A Friedl
    Research Area of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Vienna, Austria
    Microbiology 154:1229-41. 2008
    ..We further deduce that this process involves oxidative stress response and the two blue light receptor proteins BLR-1 and BLR-2, the former playing the major role...
  23. pmc The VELVET A orthologue VEL1 of Trichoderma reesei regulates fungal development and is essential for cellulase gene expression
    Razieh Karimi Aghcheh
    Institute of Chemical Engineering, Research Division Biotechnology and Microbiology, Microbiology Group, Vienna University of Technology, 1060 Vienna, Austria
    PLoS ONE 9:e112799. 2014
    ..VEL1 is also essential for cellulase gene expression, which is consistent with the assumption that their regulation by LAE1 occurs by the VELVET complex...
  24. pmc Comparative transcriptomics reveals different strategies of Trichoderma mycoparasitism
    Lea Atanasova
    Research Area Biotechnology and Microbiology, Institute of Chemical Engineering, Vienna University of Technology, Gumpendorferstrasse 1a, A 1060, Vienna, Austria
    BMC Genomics 14:121. 2013
    ..virens with tropical ecologically restricted species T. reesei during confrontations with a plant pathogenic fungus Rhizoctonia solani...
  25. ncbi request reprint Hypocrea voglmayrii sp. nov. from the Austrian Alps represents a new phylogenetic clade in Hypocrea/Trichoderma
    Walter M Jaklitsch
    Institute of Chemical Engineering, Research Area Gene Technology and Applied Biochemistry, Vienna University of Technology, Wien, Austria
    Mycologia 97:1365-78. 2005
    ..Phylogenetically, H. voglmayrii forms a distinct, isolated branch between the section Trichoderma and the H. pachybasioides clade but does not associate with any of these clades in different gene trees...
  26. pmc Review: Global nutrient profiling by Phenotype MicroArrays: a tool complementing genomic and proteomic studies in conidial fungi
    Lea Atanasova
    Research Area of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, A 1060 Vienna, Austria
    J Zhejiang Univ Sci B 11:151-68. 2010
    ..In this article, we review the background of PM applications for fungi and the methodic requirements to obtain reliable results. We also report examples of the versatility of this tool...
  27. pmc Carbon source dependence and photostimulation of conidiation in Hypocrea atroviridis
    Martina A Friedl
    Research Area of Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 1665, A 1060 Vienna, Austria
    Appl Environ Microbiol 74:245-50. 2008
    ..Our data show that the carbon source is the prime determinant for conidiation and that it influences the organism's regulation of conidiation by means of BLR-1 and BLR-2 and their cross talk with cyclic AMP...
  28. pmc The polyketide synthase gene pks4 of Trichoderma reesei provides pigmentation and stress resistance
    Lea Atanasova
    Microbiology Group, Research Area Biotechnology and Microbiology, Institute of Chemical Engineering, Vienna University of Technology, Vienna, Austria
    Eukaryot Cell 12:1499-508. 2013
    ..reesei. To our knowledge, this is the first indication that a low-molecular-weight pigment-forming PKS is involved in defense, mechanical stability, and stress resistance in fungi. ..
  29. pmc Novel traits of Trichoderma predicted through the analysis of its secretome
    Irina S Druzhinina
    Research Division Biotechnology and Microbiology, Institute of Chemical Engineering, Vienna University of Technology, Vienna, Austria
    FEMS Microbiol Lett 337:1-9. 2012
    ..We also discuss the link between Trichoderma secretome and biology of the fungus...
  30. ncbi request reprint A screening system for carbon sources enhancing beta-N-acetylglucosaminidase formation in Hypocrea atroviridis (Trichoderma atroviride)
    Verena Seidl
    Research Area Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, TU Vienna, Austria
    Microbiology 152:2003-12. 2006
    ..The screening method for the identification of carbon sources that induce enzymes or a gene of interest, as presented in this paper, can be adapted for other purposes if appropriate enzyme or reporter assays are available...
  31. ncbi request reprint Facts and challenges in the understanding of the biosynthesis of peptaibols by Trichoderma
    Christian P Kubicek
    Division of Gene Technology and Applied Biochemistry DGTAB, Institute of Chemical Engineering, Vienna University of Technology, Getreidemarkt 9 1665, Vienna, Austria
    Chem Biodivers 4:1068-82. 2007
    ..In this review article, we used the recent knowledge on biosynthesis and production of these components to speculate on some of the unknown points. We also highlight areas where further research is most urgently needed...
  32. doi request reprint Evaluation of matrix-assisted laser desorption/ionization (MALDI) preparation techniques for surface characterization of intact Fusarium spores by MALDI linear time-of-flight mass spectrometry
    Jasmin Kemptner
    Institute of Chemical Technologies and Analytics, Vienna University of Technology, Vienna, Austria
    Rapid Commun Mass Spectrom 23:877-84. 2009
    ..Numerous abundant ions throughout the investigated m/z range (m/z 1500-15 000) could be detected. Differences in the obtained mass spectral patterns allowed the differentiation of spores of various Fusarium species...
  33. pmc A complete annotation of the chromosomes of the cellulase producer Trichoderma reesei provides insights in gene clusters, their expression and reveals genes required for fitness
    Irina S Druzhinina
    Research Area Biotechnology and Microbiology, Institute of Chemical Engineering, TU Wien, 1060 Vienna, Austria
    Biotechnol Biofuels 9:75. 2016
    ..Trichoderma reesei is an industrial producer of enzymes for food, feed and biorefinery production. Its seven chromosomes have recently been assembled, thus making an investigation of its chromosome architecture possible...
  34. pmc Isotope-assisted screening for iron-containing metabolites reveals a high degree of diversity among known and unknown siderophores produced by Trichoderma spp
    Sylvia M Lehner
    Center for Analytical Chemistry, Department for Agrobiotechnology IFA Tulln, University of Natural Resources and Life Sciences BOKU, Vienna, Austria
    Appl Environ Microbiol 79:18-31. 2013
    ..Our data suggest that the high diversity of siderophores produced by Trichoderma spp. might be the result of further modifications of the nonribosomal peptide synthetase (NRPS) products and not due to diverse NRPS-encoding genes...
  35. doi request reprint HFB7 - a novel orphan hydrophobin of the Harzianum and Virens clades of Trichoderma, is involved in response to biotic and abiotic stresses
    Agnes Przylucka
    Microbiology Group, Research Area Biochemical Technology, Institute of Chemical Engineering, TU Wien, Vienna, Austria Austrian Center of Industrial Biotechnology, Graz, Austria
    Fungal Genet Biol . 2017
    ..Moreover, HFB7 likely helps in the establishment of the fungus in wetlands or other conditions related to high humidity...
  36. pmc Several steps of lateral gene transfer followed by events of 'birth-and-death' evolution shaped a fungal sorbicillinoid biosynthetic gene cluster
    Irina S Druzhinina
    Microbiology Group, Research Area Biochemical Technology, Institute of Chemical Engineering, TU Wien, Vienna, Austria
    BMC Evol Biol 16:269. 2016
    ..To reconstruct the evolutionary origin of this gene cluster, we examined the occurrence of these eight genes in ascomycetes...
  37. ncbi request reprint Direct identification of hydrophobins and their processing in Trichoderma using intact-cell MALDI-TOF MS
    Torsten Neuhof
    TU Berlin, Institut fur Chemie, FG Biochemie und Molekulare Biologie, Berlin, Germany
    FEBS J 274:841-52. 2007
    ....
  38. ncbi request reprint Trichoderma taxi sp. nov., an endophytic fungus from Chinese yew Taxus mairei
    Chu Long Zhang
    Institute of Biotechnology, Zhejiang University, Hangzhou, China
    FEMS Microbiol Lett 270:90-6. 2007
    ....
  39. pmc Application of DNA bar codes for screening of industrially important fungi: the haplotype of Trichoderma harzianum sensu stricto indicates superior chitinase formation
    Viviana Nagy
    Department of Agricultural Chemical Technology, Technical University of Budapest, Gellert ter 4, 1111 Budapest, Hungary
    Appl Environ Microbiol 73:7048-58. 2007
    ..The data illustrate that desired industrial properties may be an attribute of certain populations within a species, and screening procedures should thus include a balanced mixture of all genotypes of a given species...
  40. ncbi request reprint Intact-cell MALDI-TOF mass spectrometry analysis of peptaibol formation by the genus Trichoderma/Hypocrea: can molecular phylogeny of species predict peptaibol structures?
    Torsten Neuhof
    TU Berlin, Institut fur Chemie, FG Biochemie und Molekulare Biologie, Franklinstr 29, 10587 Berlin, Germany
    Microbiology 153:3417-37. 2007
    ....
  41. pmc Formation of atroviridin by Hypocrea atroviridis is conidiation associated and positively regulated by blue light and the G protein GNA3
    Monika Komon-Zelazowska
    Technische Universitat Wien, Institut fur Verfahrenstechnik, Umwelttechnik, und Technische Biowissenschaften, FB Gentechnik und Angewandte Biochemie, Getreidemarkt 9 166, 1060 Wien, Austria
    Eukaryot Cell 6:2332-42. 2007
    ..Our data show that formation of atroviridin by H. atroviridis occurs in a sporulation-associated manner but is uncoupled from it at the stage of GNA3...
  42. ncbi request reprint Trichoderma biodiversity in China: evidence for a North to South distribution of species in East Asia
    Chu Long Zhang
    Institute of Biotechnology, Zhejiang University, 310029 China
    FEMS Microbiol Lett 251:251-7. 2005
    ..This study therefore reveals a North-South gradient in species distribution in East Asia, and identifies Northern China as a potential center of origin of a unique haplotype of T. harzianum...
  43. ncbi request reprint TrichoBLAST: a multilocus database for Trichoderma and Hypocrea identifications
    Alexey Kopchinskiy
    Mycol Res 109:658-60. 2005
  44. ncbi request reprint Carbon source utilization by the marine Dendryphiella species D. arenaria and D. salina
    Thomas Edison E dela Cruz
    Institute of Microbiology, Technical University Braunschweig, Braunschweig, Germany
    FEMS Microbiol Ecol 58:343-53. 2006
    ..The physiological similarities exhibited by the two species support the close relationship between D. arenaria and D. salina...