Stijn Deborggraeve

Summary

Affiliation: Institute of Tropical Medicine
Country: Belgium

Publications

  1. doi request reprint Molecular analysis of archived blood slides reveals an atypical human Trypanosoma infection
    Stijn Deborggraeve
    Department of Parasitology, Institute of Tropical Medicine, 2000 Antwerp, Belgium
    Diagn Microbiol Infect Dis 61:428-33. 2008
  2. pmc Diagnostic accuracy of the Leishmania OligoC-TesT and NASBA-Oligochromatography for diagnosis of leishmaniasis in Sudan
    Alfarazdeg A Saad
    Department of Biochemistry, Khartoum University, Sudan
    PLoS Negl Trop Dis 4:e776. 2010
  3. pmc Molecular dipstick test for diagnosis of sleeping sickness
    S Deborggraeve
    Department of Parasitology, Institute of Tropical Medicine, Nationalestraat 155, B 2000 Antwerpen, Belgium
    J Clin Microbiol 44:2884-9. 2006
  4. doi request reprint Molecular diagnostics for sleeping sickness: what is the benefit for the patient?
    Stijn Deborggraeve
    Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium
    Lancet Infect Dis 10:433-9. 2010
  5. pmc T. cruzi OligoC-TesT: a simplified and standardized polymerase chain reaction format for diagnosis of Chagas disease
    Stijn Deborggraeve
    Department of Parasitology, Institute of Tropical Medicine Antwerp, Antwerp, Belgium
    PLoS Negl Trop Dis 3:e450. 2009
  6. doi request reprint A simplified and standardized polymerase chain reaction format for the diagnosis of leishmaniasis
    Stijn Deborggraeve
    Department of Parasitology, Institute of Tropical Medicine Antwerp, Antwerp, Belgium
    J Infect Dis 198:1565-72. 2008
  7. doi request reprint Diagnostic accuracy of a new Leishmania PCR for clinical visceral leishmaniasis in Nepal and its role in diagnosis of disease
    Stijn Deborggraeve
    Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium
    Trop Med Int Health 13:1378-83. 2008
  8. pmc Diagnostic accuracy of loopamp Trypanosoma brucei detection kit for diagnosis of human African trypanosomiasis in clinical samples
    Patrick Mitashi
    Institute of Tropical Medicine, Antwerp, Belgium Faculty of Medicine, Kinshasa University, Kinshasa, Democratic Republic of the Congo Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo
    PLoS Negl Trop Dis 7:e2504. 2013
  9. doi request reprint Identification of Old World Leishmania spp. by specific polymerase chain reaction amplification of cysteine proteinase B genes and rapid dipstick detection
    Thierry Laurent
    Department of Parasitology, Institute of Tropical Medicine Antwerp, 2000 Antwerp, Belgium
    Diagn Microbiol Infect Dis 63:173-81. 2009
  10. pmc Diagnostic accuracy of PCR in gambiense sleeping sickness diagnosis, staging and post-treatment follow-up: a 2-year longitudinal study
    Stijn Deborggraeve
    Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium
    PLoS Negl Trop Dis 5:e972. 2011

Collaborators

Detail Information

Publications15

  1. doi request reprint Molecular analysis of archived blood slides reveals an atypical human Trypanosoma infection
    Stijn Deborggraeve
    Department of Parasitology, Institute of Tropical Medicine, 2000 Antwerp, Belgium
    Diagn Microbiol Infect Dis 61:428-33. 2008
    ....
  2. pmc Diagnostic accuracy of the Leishmania OligoC-TesT and NASBA-Oligochromatography for diagnosis of leishmaniasis in Sudan
    Alfarazdeg A Saad
    Department of Biochemistry, Khartoum University, Sudan
    PLoS Negl Trop Dis 4:e776. 2010
    ..We here present the phase II evaluation of both tests for diagnosis of visceral leishmaniasis (VL), cutaneous leishmaniasis (CL) and post kala-azar dermal leishmaniasis (PKDL) in Sudan...
  3. pmc Molecular dipstick test for diagnosis of sleeping sickness
    S Deborggraeve
    Department of Parasitology, Institute of Tropical Medicine, Nationalestraat 155, B 2000 Antwerpen, Belgium
    J Clin Microbiol 44:2884-9. 2006
    ..HAT-PCR-OC is a promising new tool for diagnosis of sleeping sickness in laboratory settings, and the diagnostic format described here may have wider application for other infectious diseases...
  4. doi request reprint Molecular diagnostics for sleeping sickness: what is the benefit for the patient?
    Stijn Deborggraeve
    Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium
    Lancet Infect Dis 10:433-9. 2010
    ..The current formats are not applicable to field conditions, and simplification, standardisation, and proper test evaluation in the target setting should be the main focus for future development...
  5. pmc T. cruzi OligoC-TesT: a simplified and standardized polymerase chain reaction format for diagnosis of Chagas disease
    Stijn Deborggraeve
    Department of Parasitology, Institute of Tropical Medicine Antwerp, Antwerp, Belgium
    PLoS Negl Trop Dis 3:e450. 2009
    ..PCR has evolved into one of the most promising tools for T. cruzi detection in the diagnosis and control of Chagas disease. However, general use of the technique is hampered by its complexity and the lack of standardization...
  6. doi request reprint A simplified and standardized polymerase chain reaction format for the diagnosis of leishmaniasis
    Stijn Deborggraeve
    Department of Parasitology, Institute of Tropical Medicine Antwerp, Antwerp, Belgium
    J Infect Dis 198:1565-72. 2008
    ..However, microscopy generally shows low sensitivity and requires invasive sampling...
  7. doi request reprint Diagnostic accuracy of a new Leishmania PCR for clinical visceral leishmaniasis in Nepal and its role in diagnosis of disease
    Stijn Deborggraeve
    Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium
    Trop Med Int Health 13:1378-83. 2008
    ..To develop a new PCR for Leishmania detection and to estimate its diagnostic accuracy in a visceral leishmaniasis (VL) endemic area...
  8. pmc Diagnostic accuracy of loopamp Trypanosoma brucei detection kit for diagnosis of human African trypanosomiasis in clinical samples
    Patrick Mitashi
    Institute of Tropical Medicine, Antwerp, Belgium Faculty of Medicine, Kinshasa University, Kinshasa, Democratic Republic of the Congo Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo
    PLoS Negl Trop Dis 7:e2504. 2013
    ..b. gambiense HAT patients, HAT suspects and healthy endemic controls from the Democratic Republic of the Congo (DRC)...
  9. doi request reprint Identification of Old World Leishmania spp. by specific polymerase chain reaction amplification of cysteine proteinase B genes and rapid dipstick detection
    Thierry Laurent
    Department of Parasitology, Institute of Tropical Medicine Antwerp, 2000 Antwerp, Belgium
    Diagn Microbiol Infect Dis 63:173-81. 2009
    ..As such, they can be implemented by research and health centers having access to culturing, DNA isolation, and PCR...
  10. pmc Diagnostic accuracy of PCR in gambiense sleeping sickness diagnosis, staging and post-treatment follow-up: a 2-year longitudinal study
    Stijn Deborggraeve
    Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium
    PLoS Negl Trop Dis 5:e972. 2011
    ..The polymerase chain reaction (PCR) has been proposed for diagnosis, staging and post-treatment follow-up of sleeping sickness but no large-scale clinical evaluations of its diagnostic accuracy have taken place yet...
  11. pmc The Trypanosoma cruzi satellite DNA OligoC-TesT and Trypanosoma cruzi kinetoplast DNA OligoC-TesT for diagnosis of Chagas disease: a multi-cohort comparative evaluation study
    Koen De Winne
    Department of Biomedical Sciences, Parasite Diagnostics Unit, Institute of Tropical Medicine, Antwerp, Belgium
    PLoS Negl Trop Dis 8:e2633. 2014
    ..The sensitivity of the test is lower for discrete typing unit (DTU) TcI than for TcII-VI and the test has not been evaluated in chronic Chagas disease patients...
  12. doi request reprint Recent progress in molecular diagnosis of sleeping sickness
    Stijn Deborggraeve
    Department of Biomedical Sciences, Institute of Tropical Medicine Antwerp, Nationalestraat 155, 2000 Antwerpen, Belgium
    Expert Rev Mol Diagn 12:719-30. 2012
    ..In addition to the technological progress, the authors also discuss the diagnostic performance of molecular tests in the most recent clinical evaluation studies and briefly present some viewpoints for the near future...
  13. pmc Apolipoprotein L1 Variant Associated with Increased Susceptibility to Trypanosome Infection
    Bart Cuypers
    Biomedical Sciences Department, Institute of Tropical Medicine Antwerp, Antwerp, Belgium Advanced Database Research and Modelling ADReM, Department of Mathematics and Computer Science, University of Antwerp, Antwerp, Belgium
    MBio 7:e02198-15. 2016
    ....
  14. doi request reprint How can molecular diagnostics contribute to the elimination of human African trypanosomiasis?
    Philippe Büscher
    Department of Biomedical Sciences, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerpen, Belgium
    Expert Rev Mol Diagn 15:607-15. 2015
    ..Also discussed is how molecular diagnostics can play an important role in the process toward the elimination of HAT. ..
  15. doi request reprint Diagnosis of trypanosomatid infections: targeting the spliced leader RNA
    Pablo González-Andrade
    Biomedical Sciences Department, Institute of Tropical Medicine, Antwerp, Belgium
    J Mol Diagn 16:400-4. 2014
    ..The SL-RNA is thus an attractive new molecular target for next-generation diagnostics in diseases caused by trypanosomatids. ..