Susan Nadin-Davis

Summary

Affiliation: Canadian Food Inspection Agency
Country: Canada

Publications

  1. ncbi request reprint Lyssavirus P gene characterisation provides insights into the phylogeny of the genus and identifies structural similarities and diversity within the encoded phosphoprotein
    S A Nadin-Davis
    Rabies Centre of Expertise, Animal Diseases Research Institute, Canadian Food Inspection Agency, 3851 Fallowfield Road, Nepean, Ontario, Canada
    Virology 298:286-305. 2002
  2. pmc A molecular epidemiological study of rabies in Cuba
    S A Nadin-Davis
    Rabies Center of Expertise, Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, Ottawa, Canada
    Epidemiol Infect 134:1313-24. 2006
  3. pmc Persistence of genetic variants of the arctic fox strain of Rabies virus in southern Ontario
    Susan A Nadin-Davis
    Centre of Expertise for Rabies, Canadian Food Inspection Agency, Ottawa Laboratory Fallowfield, 3851 Fallowfield Road, Ottawa, Ontario K2H 8P9
    Can J Vet Res 70:11-9. 2006
  4. ncbi request reprint The molecular epidemiology of rabies associated with chiropteran hosts in Mexico
    Susan A Nadin-Davis
    Rabies Center of Expertise, Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency CFIA, 3851 Fallowfield Road, Ottawa, Ont, Canada K2H 8P9
    Virus Res 117:215-26. 2006
  5. pmc A molecular epidemiological analysis of the incursion of the raccoon strain of rabies virus into Canada
    S A Nadin-Davis
    Rabies Centre of Expertise, Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, Ottawa, Ontario, Canada
    Epidemiol Infect 134:534-47. 2006
  6. ncbi request reprint A molecular epidemiological study of rabies in Puerto Rico
    Susan A Nadin-Davis
    Rabies Center of Expertise, Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, 3851 Fallowfield Road, Ottawa, K2H 8P9 Canada
    Virus Res 131:8-15. 2008
  7. pmc Use of discriminatory probes for strain typing of formalin-fixed, rabies virus-infected tissues by in situ hybridization
    Susan A Nadin-Davis
    Rabies Centre of Expertise, Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, Nepean, Ontario K2H 8P9, Canada
    J Clin Microbiol 41:4343-52. 2003
  8. ncbi request reprint Origins of the rabies viruses associated with an outbreak in Newfoundland during 2002-2003
    Susan Nadin-Davis
    Centre of Expertise for Rabies, Ottawa Laboratory Fallowfield, 3851 Fallowfield Rd, Canadian Food Inspection Agency, Ottawa, Ontario K2H 8P9, Canada
    J Wildl Dis 44:86-98. 2008
  9. pmc Emergence of Arctic-like rabies lineage in India
    Susan A Nadin-Davis
    Canadian Food Inspection Agency, Ottawa, Ontario, Canada
    Emerg Infect Dis 13:111-6. 2007
  10. ncbi request reprint Era vaccine-derived cases of rabies in wildlife and domestic animals in Ontario, Canada, 1989-2004
    Christine Fehlner-Gardiner
    Centre of Expertise for Rabies, Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, 3851 Fallowfield Road, Ottawa, Ontario K2H 8P9, Canada
    J Wildl Dis 44:71-85. 2008

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Lyssavirus P gene characterisation provides insights into the phylogeny of the genus and identifies structural similarities and diversity within the encoded phosphoprotein
    S A Nadin-Davis
    Rabies Centre of Expertise, Animal Diseases Research Institute, Canadian Food Inspection Agency, 3851 Fallowfield Road, Nepean, Ontario, Canada
    Virology 298:286-305. 2002
    ....
  2. pmc A molecular epidemiological study of rabies in Cuba
    S A Nadin-Davis
    Rabies Center of Expertise, Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, Ottawa, Canada
    Epidemiol Infect 134:1313-24. 2006
    ..Given the recent emergence of human cases due to bat contact in Cuba, this study also included a single insectivorous bat specimen which was found to most closely resemble the rabies viruses known to circulate in Mexican vampire bats...
  3. pmc Persistence of genetic variants of the arctic fox strain of Rabies virus in southern Ontario
    Susan A Nadin-Davis
    Centre of Expertise for Rabies, Canadian Food Inspection Agency, Ottawa Laboratory Fallowfield, 3851 Fallowfield Road, Ottawa, Ontario K2H 8P9
    Can J Vet Res 70:11-9. 2006
    ..An outbreak that occurred in northern Ontario north and west of North Bay and in the neighboring border areas of Quebec in 2000-2001 was due to renewed incursion of the ARC.T5 variant from more northerly areas...
  4. ncbi request reprint The molecular epidemiology of rabies associated with chiropteran hosts in Mexico
    Susan A Nadin-Davis
    Rabies Center of Expertise, Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency CFIA, 3851 Fallowfield Road, Ottawa, Ont, Canada K2H 8P9
    Virus Res 117:215-26. 2006
    ..A single isolate recovered from a cat represents a new viral variant not previously identified in North America that probably circulates in a species of insectivorous bat...
  5. pmc A molecular epidemiological analysis of the incursion of the raccoon strain of rabies virus into Canada
    S A Nadin-Davis
    Rabies Centre of Expertise, Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, Ottawa, Ontario, Canada
    Epidemiol Infect 134:534-47. 2006
    ..These data provide a framework for study of future incursions of this rabies strain into Canada...
  6. ncbi request reprint A molecular epidemiological study of rabies in Puerto Rico
    Susan A Nadin-Davis
    Rabies Center of Expertise, Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, 3851 Fallowfield Road, Ottawa, K2H 8P9 Canada
    Virus Res 131:8-15. 2008
    ..This study clearly establishes the distinct origins of the rabies viruses now circulating on these two Caribbean islands...
  7. pmc Use of discriminatory probes for strain typing of formalin-fixed, rabies virus-infected tissues by in situ hybridization
    Susan A Nadin-Davis
    Rabies Centre of Expertise, Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, Nepean, Ontario K2H 8P9, Canada
    J Clin Microbiol 41:4343-52. 2003
    ..This technique provides a typing regimen for rabies virus isolates submitted in a form that is normally recalcitrant to alternate typing strategies...
  8. ncbi request reprint Origins of the rabies viruses associated with an outbreak in Newfoundland during 2002-2003
    Susan Nadin-Davis
    Centre of Expertise for Rabies, Ottawa Laboratory Fallowfield, 3851 Fallowfield Rd, Canadian Food Inspection Agency, Ottawa, Ontario K2H 8P9, Canada
    J Wildl Dis 44:86-98. 2008
    ....
  9. pmc Emergence of Arctic-like rabies lineage in India
    Susan A Nadin-Davis
    Canadian Food Inspection Agency, Ottawa, Ontario, Canada
    Emerg Infect Dis 13:111-6. 2007
    ....
  10. ncbi request reprint Era vaccine-derived cases of rabies in wildlife and domestic animals in Ontario, Canada, 1989-2004
    Christine Fehlner-Gardiner
    Centre of Expertise for Rabies, Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, 3851 Fallowfield Road, Ottawa, Ontario K2H 8P9, Canada
    J Wildl Dis 44:71-85. 2008
    ..These results are consistent with previous reports of the rare detection of ERA vaccine-induced rabies and with laboratory studies of ERA pathogenicity...
  11. doi request reprint Lyssaviruses: current trends
    Susan A Nadin-Davis
    Centre of Expertise for Rabies, Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, Ottawa, ON, Canada
    Adv Virus Res 71:207-50. 2008
    ..This review summarizes much of the increased knowledge about rabies that has resulted from such studies but acknowledges that this is still insufficient to allow rational attempts at curing those who present with clinical disease...
  12. ncbi request reprint Antigenic and genetic divergence of rabies viruses from bat species indigenous to Canada
    S A Nadin-Davis
    Rabies Centre of Expertise, Animal Diseases Research Institute, Canadian Food Inspection Agency, P O Box 11300, Station H, 3851 Fallowfield Road, Ont, K2H8P9, Nepean, Canada
    Virus Res 74:139-56. 2001
    ..Finally, these sequences permitted examination of the evolutionary relationship of American bat rabies viruses within the Lyssavirus genus...
  13. doi request reprint Development of real-time reverse transcriptase polymerase chain reaction methods for human rabies diagnosis
    Susan A Nadin-Davis
    Ottawa Laboratory, Canadian Food Inspection Agency, Ontario, Canada
    J Med Virol 81:1484-97. 2009
    ..However in this case it would appear that reduction of the viral load in the patient's saliva over time did not appear to correlate well with clearance of viral components from the brain...
  14. doi request reprint In vitro and in vivo genetic stability studies of a human adenovirus type 5 recombinant rabies glycoprotein vaccine (ONRAB)
    M Kimberly Knowles
    Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, 3851 Fallowfield Road, Ottawa, Ontario K2H 8P9, Canada
    Vaccine 27:2662-8. 2009
    ..These trials demonstrated the stability of the insert gene of ONRAB during in vivo and in vitro passaging...
  15. doi request reprint Safety studies on an adenovirus recombinant vaccine for rabies (AdRG1.3-ONRAB) in target and non-target species
    M Kimberly Knowles
    Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, Ottawa, Ontario, Canada
    Vaccine 27:6619-26. 2009
    ..8% of fecal specimens found to be positive. The low rates of recovery of vaccine virus from tissues, feces and the oral cavity suggest that the likelihood of ONRAB causing a negative impact on wildlife species is unlikely...
  16. doi request reprint Spatial and temporal dynamics of rabies virus variants in big brown bat populations across Canada: footprints of an emerging zoonosis
    Susan A Nadin-Davis
    Centre of Expertise for Rabies, Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, Ottawa, Ontario, Canada
    Mol Ecol 19:2120-36. 2010
    ..We discuss how this bat population structure has affected the historical spread of rabies virus variants across the country and the potential impact of these events on public health concerns regarding rabies...
  17. doi request reprint Characterization of a panel of anti-phosphoprotein monoclonal antibodies generated against the raccoon strain of rabies virus
    Susan A Nadin-Davis
    Centre of Expertise for Rabies, Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, 3851 Fallowfield Rd, Ottawa, Ontario, Canada
    Virus Res 152:126-36. 2010
    ..The utility of these MAbs to detect truncated versions of the P product may facilitate more fundamental studies on the function of this rabies virus protein...
  18. pmc Laboratory diagnosis of rabies in Canada for calendar year 2006
    Christine Fehlner-Gardiner
    Canadian Food Inspection Agency, Ottawa Laboratory Fallowfield, Ottawa, Ontario
    Can Vet J 49:359-61. 2008
  19. ncbi request reprint Evidence for virus closely related to avian myeloblastosis-associated virus type 1 in a commercial stock of chickens
    J Lloyd Spencer
    Canadian Food Inspection Agency, Ottawa Laboratory Fallowfield, Animal Diseases Research Institute, 3851 Fallowfield Road, Ottawa, Ontario, Canada K2H 8P9
    Avian Pathol 32:383-90. 2003
    ....
  20. pmc A panel of monoclonal antibodies targeting the rabies virus phosphoprotein identifies a highly variable epitope of value for sensitive strain discrimination
    S A Nadin-Davis
    Rabies Centre of Expertise, Animal Diseases Research Institute, Canadian Food Inspection Agency, Nepean, Ontario, Canada
    J Clin Microbiol 38:1397-403. 2000
    ..These anti-P MAbs are potentially useful tools for lyssavirus identification and discrimination...
  21. ncbi request reprint Polymerase chain reaction protocols for rabies virus discrimination
    S A Nadin-Davis
    Rabies Centre of Expertise, Animal Diseases Research Institute, Canadian Food Inspection Agency, Nepean, Ont
    J Virol Methods 75:1-8. 1998
    ..Such methods can be adapted readily for use in other regions harbouring multiple overlapping RV reservoirs...
  22. doi request reprint Complete genome sequence of a raccoon rabies virus isolate
    Annamaria G Szanto
    DNA Profiling and Forensic Research Centre, Trent University, DNA Building, 2140 East Bank Drive, Peterborough, Ontario K9J 7B8, Canada
    Virus Res 136:130-9. 2008
    ..Analysis of L gene codon substitution patterns favoured models that supported positive selection, but only one site, corresponding to Leu62 of the RRV L protein, was identified as being under weak positive selection...
  23. doi request reprint Characterization of human rabies virus vaccine strain in China
    Jialiang Du
    Department of Viral Encephalitis, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention and State Key Laboratory for Infectious Disease Prevention and Control, Xuan Wu District, Beijing, China
    Virus Res 135:260-6. 2008
    ..In addition, some mutations and new functional regions were discovered that are presumed crucial to the function of leader region and L protein. There is an equal role for all five genes in the phylogenetics of rabies virus...
  24. ncbi request reprint A molecular epidemiological study targeting the glycoprotein gene of rabies virus isolates from China
    Sheng Li Meng
    Wuhan Institute of Biological Products, Wuhan 430060, China
    Virus Res 124:125-38. 2007
    ..The predicted glycoprotein sequences of these RABVs variants are presented and discussed with respect to the utility of the anti-rabies biologicals currently employed in China...
  25. ncbi request reprint Sensitive and specific detection of bovine immunodeficiency virus and bovine syncytial virus by 5' Taq nuclease assays with fluorescent 3' minor groove binder-DNA probes
    Ala E Lew
    Agency for Food and Fibre Sciences, Queensland Department of Primary Industries, c o Locked Mail Bag No 4, Moorooka, 4105, QLD, Australia
    J Virol Methods 116:1-9. 2004
    ..These methods could be applied to future studies requiring sensitive detection of these two bovine retroviruses...