A Percival-Smith

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. ncbi Genetic characterization of the role of the two HOX proteins, Proboscipedia and Sex Combs Reduced, in determination of adult antennal, tarsal, maxillary palp and proboscis identities in Drosophila melanogaster
    A Percival-Smith
    Department of Zoology, University of Western Ontario, London, Canada
    Development 124:5049-62. 1997
  2. ncbi Analysis of murine HOXA-2 activity in Drosophila melanogaster
    A Percival-Smith
    Department of Zoology, University of Western Ontario, London, Canada
    Dev Genet 24:336-44. 1999
  3. pmc Analysis in Drosophila melanogaster of the interaction between sex combs reduced and extradenticle activity in the determination of tarsus and arista identity
    A Percival-Smith
    Department of Zoology, University of Western Ontario, London, Ontario N6A 5B7, Canada
    Genetics 150:189-98. 1998
  4. pmc Genetic characterization of the homeodomain-independent activity of the Drosophila fushi tarazu gene product
    D Hyduk
    Department of Zoology, University of Western Ontario, London, Canada
    Genetics 142:481-92. 1996
  5. ncbi Analysis of Drosophila proboscipedia mutant alleles
    I Tayyab
    Department of Biology, University of Western Ontario, London, Canada
    Genome 47:600-9. 2004
  6. doi Increased abundance of frost mRNA during recovery from cold stress is not essential for cold tolerance in adult Drosophila melanogaster
    H Udaka
    Department of Biology, The University of Western Ontario, London, ON, Canada
    Insect Mol Biol 22:541-50. 2013
  7. ncbi The nuclear receptor homologue Ftz-F1 and the homeodomain protein Ftz are mutually dependent cofactors
    A Guichet
    Developmental Biology Programme, European Molecular Biology Laboratory, Heidelberg, Germany
    Nature 385:548-52. 1997
  8. ncbi The structure of the homeodomain and its functional implications
    W J Gehring
    University of Basel, Switzerland
    Trends Genet 6:323-9. 1990
  9. pmc FTZ-Factor1 and Fushi tarazu interact via conserved nuclear receptor and coactivator motifs
    C J Schwartz
    Banting and Best Department of Medical Research, University of Toronto and C H Best Institute, 112 College Street, Toronto, Ontario, Canada
    EMBO J 20:510-9. 2001
  10. pmc DNA binding properties of the purified Antennapedia homeodomain
    M Affolter
    Biozentrum, University of Basel, Switzerland
    Proc Natl Acad Sci U S A 87:4093-7. 1990

Collaborators

Detail Information

Publications12

  1. ncbi Genetic characterization of the role of the two HOX proteins, Proboscipedia and Sex Combs Reduced, in determination of adult antennal, tarsal, maxillary palp and proboscis identities in Drosophila melanogaster
    A Percival-Smith
    Department of Zoology, University of Western Ontario, London, Canada
    Development 124:5049-62. 1997
    ..This study characterizes a combinatorial interaction between two HOX proteins; a mechanism that may have a major role in patterning the anterior-posterior axis of other animals...
  2. ncbi Analysis of murine HOXA-2 activity in Drosophila melanogaster
    A Percival-Smith
    Department of Zoology, University of Western Ontario, London, Canada
    Dev Genet 24:336-44. 1999
    ..These results indicate that the only activity that PB and HOXA-2 weakly share is the inhibition of SCR activity, and that murine HOXA-5 and Drosophila SCR do not share inhibition by PB activity...
  3. pmc Analysis in Drosophila melanogaster of the interaction between sex combs reduced and extradenticle activity in the determination of tarsus and arista identity
    A Percival-Smith
    Department of Zoology, University of Western Ontario, London, Ontario N6A 5B7, Canada
    Genetics 150:189-98. 1998
    ....
  4. pmc Genetic characterization of the homeodomain-independent activity of the Drosophila fushi tarazu gene product
    D Hyduk
    Department of Zoology, University of Western Ontario, London, Canada
    Genetics 142:481-92. 1996
    ..Activation of the ftz enhancer by ectopic expression of FTZ activity was effective only during gastrulation and germ band extension. In the discussion, we propose an explanation for these results...
  5. ncbi Analysis of Drosophila proboscipedia mutant alleles
    I Tayyab
    Department of Biology, University of Western Ontario, London, Canada
    Genome 47:600-9. 2004
    ..PB and SCR do not interact directly with one another in a co-immunoprecipitation assay and in a yeast two-hybrid analysis, which suggests the pb-Scr genetic interaction is not mediated by a direct interaction between PB and SCR...
  6. doi Increased abundance of frost mRNA during recovery from cold stress is not essential for cold tolerance in adult Drosophila melanogaster
    H Udaka
    Department of Biology, The University of Western Ontario, London, ON, Canada
    Insect Mol Biol 22:541-50. 2013
    ..Thus, cold-induced Fst accumulation is not essential for cold tolerance measured as chill-coma recovery time, survival to acute cold stress and RCH response in adult D. melanogaster. ..
  7. ncbi The nuclear receptor homologue Ftz-F1 and the homeodomain protein Ftz are mutually dependent cofactors
    A Guichet
    Developmental Biology Programme, European Molecular Biology Laboratory, Heidelberg, Germany
    Nature 385:548-52. 1997
    ..This interaction suggests that other nuclear receptor/homeodomain protein interactions maybe important and common in developing organisms...
  8. ncbi The structure of the homeodomain and its functional implications
    W J Gehring
    University of Basel, Switzerland
    Trends Genet 6:323-9. 1990
    ..Isolated homeodomains bind with high affinity to specific DNA sequences. Thus, the structure-function relationship is highly conserved in evolution...
  9. pmc FTZ-Factor1 and Fushi tarazu interact via conserved nuclear receptor and coactivator motifs
    C J Schwartz
    Banting and Best Department of Medical Research, University of Toronto and C H Best Institute, 112 College Street, Toronto, Ontario, Canada
    EMBO J 20:510-9. 2001
    ..These unexpected findings have important implications for the conserved homologs of the two proteins...
  10. pmc DNA binding properties of the purified Antennapedia homeodomain
    M Affolter
    Biozentrum, University of Basel, Switzerland
    Proc Natl Acad Sci U S A 87:4093-7. 1990
    ..The DNA binding properties of the Antp HD and prokaryotic DNA binding domains that share a helix-turn-helix motif are compared...
  11. ncbi Homeodomain-independent activity of the fushi tarazu polypeptide in Drosophila embryos
    V D Fitzpatrick
    Banting and Best Department of Medical Research, Charles H Best Institute, University of Toronto, Ontario, Canada
    Nature 356:610-2. 1992
    ..Here we show that the same phenotype is induced by ectopic expression of a ftz polypeptide containing a deletion in the homeodomain. Thus, ftz can alter gene expression without binding directly to DNA...
  12. pmc The interaction with DNA of wild-type and mutant fushi tarazu homeodomains
    A Percival-Smith
    University of Basel, Department of Cell Biology, Switzerland
    EMBO J 9:3967-74. 1990
    ..These three points of contact allowed us to propose a crude orientation of the ftz HD within the protein-DNA complex. We find that the ftz HD and the Antp HD peptides contact DNA in a similar way...