Mauricio A Retamal

Summary

Affiliation: Facultad de Medicina
Country: Chile

Publications

  1. pmc Modulation of Cx46 hemichannels by nitric oxide
    Mauricio A Retamal
    Department of Cell Physiology and Molecular Biophysics, Texas Tech University Health Sciences Center, and Center for Membrane Protein Research, Lubbock, Texas, USA
    Am J Physiol Cell Physiol 296:C1356-63. 2009
  2. pmc Voltage-dependent facilitation of Cx46 hemichannels
    Mauricio A Retamal
    Laboratorio de Fisiologia, Facultad de Medicina, Clinica Alemana Universidad Del Desarrollo, Avenida Las Condes 12438, Santiago, Chile
    Am J Physiol Cell Physiol 298:C132-9. 2010
  3. pmc Biphasic effect of linoleic acid on connexin 46 hemichannels
    Mauricio A Retamal
    Laboratorio de Fisiologia, Clinica Alemana Universidad Del Desarrollo, Santiago, Chile
    Pflugers Arch 461:635-43. 2011
  4. doi request reprint Linoleic acid induces opening of connexin26 hemichannels through a PI3K/Akt/Ca(2+)-dependent pathway
    Vania Figueroa
    Departamento de Fisiologia, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Biochim Biophys Acta 1828:1169-79. 2013
  5. pmc Connexin hemichannel composition determines the FGF-1-induced membrane permeability and free [Ca2+]i responses
    Kurt A Schalper
    Departamento de Ciencias Fisiologicas, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Mol Biol Cell 19:3501-13. 2008
  6. doi request reprint Cell membrane permeabilization via connexin hemichannels in living and dying cells
    Juan C Saez
    Departamento de Ciencias Fisiologicas, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Exp Cell Res 316:2377-89. 2010
  7. pmc Connexin-based gap junction hemichannels: gating mechanisms
    Juan C Saez
    Departamento de Ciencias Fisiologicas, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Biochim Biophys Acta 1711:215-24. 2005
  8. pmc Functional hemichannels formed by human connexin 26 expressed in bacteria
    Mariana C Fiori
    Department of Cell Physiology and Molecular Biophysics, Texas Tech University Health Sciences Center, Lubbock, TX 79430 6551, U S A
    Biosci Rep 35:. 2015
  9. pmc Extracellular Cysteine in Connexins: Role as Redox Sensors
    Mauricio A Retamal
    Facultad de Medicina, Centro de Fisiología Celular e Integrativa, Clínica Alemana Universidad del Desarrollo Santiago, Chile
    Front Physiol 7:1. 2016
  10. ncbi request reprint Possible involvement of different connexin43 domains in plasma membrane permeabilization induced by ischemia-reperfusion
    Mauricio A Retamal
    Departamento de Ciencias Fisiologicas, Pontificia Universidad Catolica de Chile, Alameda 340, Santiago, Chile
    J Membr Biol 218:49-63. 2007

Collaborators

Detail Information

Publications14

  1. pmc Modulation of Cx46 hemichannels by nitric oxide
    Mauricio A Retamal
    Department of Cell Physiology and Molecular Biophysics, Texas Tech University Health Sciences Center, and Center for Membrane Protein Research, Lubbock, Texas, USA
    Am J Physiol Cell Physiol 296:C1356-63. 2009
    ..However, it is unlikely that NO induces cataract formation due to the hemichannel activation, because at normal resting potential, NO had no major effects on Cx46 hemichannel permeability...
  2. pmc Voltage-dependent facilitation of Cx46 hemichannels
    Mauricio A Retamal
    Laboratorio de Fisiologia, Facultad de Medicina, Clinica Alemana Universidad Del Desarrollo, Avenida Las Condes 12438, Santiago, Chile
    Am J Physiol Cell Physiol 298:C132-9. 2010
    ..The results suggest that Cx46 hemichannels show a cooperative activation independent of their COOH-terminal domain...
  3. pmc Biphasic effect of linoleic acid on connexin 46 hemichannels
    Mauricio A Retamal
    Laboratorio de Fisiologia, Clinica Alemana Universidad Del Desarrollo, Santiago, Chile
    Pflugers Arch 461:635-43. 2011
    ..The block by unsaturated fatty acids reported here opens the possibility that increases in the concentration of these lipids in the lens induce cataract formation by blocking Cx46 hemichannels...
  4. doi request reprint Linoleic acid induces opening of connexin26 hemichannels through a PI3K/Akt/Ca(2+)-dependent pathway
    Vania Figueroa
    Departamento de Fisiologia, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Biochim Biophys Acta 1828:1169-79. 2013
    ..Since LA is an essential polyunsaturated fatty acid, its effect on HCs might be relevant to cell growth as well as to cellular functions of differentiated cells such as audition...
  5. pmc Connexin hemichannel composition determines the FGF-1-induced membrane permeability and free [Ca2+]i responses
    Kurt A Schalper
    Departamento de Ciencias Fisiologicas, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Mol Biol Cell 19:3501-13. 2008
    ..The cell density of Cx26 and Cx43 HeLa transfectants cultured in serum-free medium was differentially affected by FGF-1. Thus, the FGF-1-induced cell permeabilization and derived consequences depend on the Cx composition of HCs...
  6. doi request reprint Cell membrane permeabilization via connexin hemichannels in living and dying cells
    Juan C Saez
    Departamento de Ciencias Fisiologicas, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Exp Cell Res 316:2377-89. 2010
    ....
  7. pmc Connexin-based gap junction hemichannels: gating mechanisms
    Juan C Saez
    Departamento de Ciencias Fisiologicas, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Biochim Biophys Acta 1711:215-24. 2005
    ..Taken together, the data indicate that hemichannels are gated by multiple mechanisms that independently or cooperatively affect their open probability under physiological as well as pathological conditions...
  8. pmc Functional hemichannels formed by human connexin 26 expressed in bacteria
    Mariana C Fiori
    Department of Cell Physiology and Molecular Biophysics, Texas Tech University Health Sciences Center, Lubbock, TX 79430 6551, U S A
    Biosci Rep 35:. 2015
    ..The E. coli-based expression system has high potential for structural studies and high-throughput functional screening of HCs...
  9. pmc Extracellular Cysteine in Connexins: Role as Redox Sensors
    Mauricio A Retamal
    Facultad de Medicina, Centro de Fisiología Celular e Integrativa, Clínica Alemana Universidad del Desarrollo Santiago, Chile
    Front Physiol 7:1. 2016
    ..Future studies on this topic will offer new insight into hemichannel function, thereby expanding the understanding of the contribution of hemichannels to disease progression. ..
  10. ncbi request reprint Possible involvement of different connexin43 domains in plasma membrane permeabilization induced by ischemia-reperfusion
    Mauricio A Retamal
    Departamento de Ciencias Fisiologicas, Pontificia Universidad Catolica de Chile, Alameda 340, Santiago, Chile
    J Membr Biol 218:49-63. 2007
    ....
  11. pmc Carbon monoxide (CO) is a novel inhibitor of connexin hemichannels
    Carmen G León-Paravic
    From the Centro de Fisiología Celular e Integrativa, Facultad de Medicina, Clinica Alemana Universidad Del Desarrollo, Santiago, Chile 7690000 and
    J Biol Chem 289:36150-7. 2014
    ..The inhibition of HCs could help to understand some of the biological actions of CO in physiological and pathological conditions. ..
  12. doi request reprint Carbon monoxide: A new player in the redox regulation of connexin hemichannels
    Mauricio A Retamal
    Centro de Fisiología Celular e Integrativa, Facultad de Medicina, Clinica Alemana Universidad Del Desarrollo, Santiago, Chile
    IUBMB Life 67:428-37. 2015
    ..Here, we review the most recent results regarding the effect of CO on Cx hemichannels and their possible repercussions on pathologies...
  13. doi request reprint Release of gliotransmitters through astroglial connexin 43 hemichannels is necessary for fear memory consolidation in the basolateral amygdala
    Jimmy Stehberg
    Laboratorio de Neurobiologia, Departamento de Ciencias Biologicas, Facultad de Ciencias Biologicas and Facultad de Medicina, Universidad Andres Bello, Santiago, Chile
    FASEB J 26:3649-57. 2012
    ....