Song Kedong

Summary

Affiliation: Dalian University of Technology
Country: China

Publications

  1. ncbi Research progress on reconstruction of meniscus in tissue engineering
    Yu Zhang
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, China
    J Sports Med Phys Fitness . 2016
  2. doi Characterization of human adipose tissue-derived stem cells in vitro culture and in vivo differentiation in a temperature-sensitive chitosan/β- glycerophosphate/collagen hybrid hydrogel
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China Electronic address
    Mater Sci Eng C Mater Biol Appl 70:231-240. 2017
  3. doi Fabrication and development of artificial osteochondral constructs based on cancellous bone/hydrogel hybrid scaffold
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, 116024, China
    J Mater Sci Mater Med 27:114. 2016
  4. doi Hematopoietic stem cells: multiparameter regulation
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, 116024, China
    Hum Cell 29:53-7. 2016
  5. doi Fabrication and detection of tissue engineered bone aggregates based on encapsulated human ADSCs within hybrid calcium alginate/bone powder gel-beads in a spinner flask
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China Electronic address
    Mater Sci Eng C Mater Biol Appl 62:787-94. 2016
  6. doi Numberical simulation of fluid flow and three-dimensional expansion of tissue engineering seed cells in large scale inside a novel rotating wall hollow fiber membrane bioreactor
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, 116024, China
    Bioprocess Biosyst Eng 38:1527-40. 2015
  7. doi In vitro culture and harvest of BMMSCs on the surface of a novel thermosensitive glass microcarrier
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China Electronic address
    Mater Sci Eng C Mater Biol Appl 58:324-30. 2016
  8. doi Three-dimensional dynamic fabrication of engineered cartilage based on chitosan/gelatin hybrid hydrogel scaffold in a spinner flask with a special designed steel frame
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China Electronic address
    Mater Sci Eng C Mater Biol Appl 55:384-92. 2015
  9. doi Mass transfer analysis of growth and substance metabolism of NSCs cultured in collagen-based scaffold in vitro
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, 116024, China
    Appl Biochem Biotechnol 174:2114-30. 2014
  10. doi Dynamic fabrication of tissue-engineered bone substitutes based on derived cancellous bone scaffold in a spinner flask bioreactor system
    Song Kedong
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, 116024, China
    Appl Biochem Biotechnol 174:1331-43. 2014

Collaborators

Detail Information

Publications29

  1. ncbi Research progress on reconstruction of meniscus in tissue engineering
    Yu Zhang
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, China
    J Sports Med Phys Fitness . 2016
    ..This review discusses aspects of meniscus tissue engineering, which is relative to the clinical treatment of meniscus injuries for further support and establishment of fundamental and clinical studies...
  2. doi Characterization of human adipose tissue-derived stem cells in vitro culture and in vivo differentiation in a temperature-sensitive chitosan/β- glycerophosphate/collagen hybrid hydrogel
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China Electronic address
    Mater Sci Eng C Mater Biol Appl 70:231-240. 2017
    ..Histology analysis indicated that induced ADSCs-C/GP/Co hydrogel has a greater number of adipocytes and vascularized adipose tissues compared with non-induced ADSCs-C/GP/Co hydrogel...
  3. doi Fabrication and development of artificial osteochondral constructs based on cancellous bone/hydrogel hybrid scaffold
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, 116024, China
    J Mater Sci Mater Med 27:114. 2016
    ..Therefore, a bi-layered composite scaffold is an appropriate candidate for fabrication of osteochondral tissue...
  4. doi Hematopoietic stem cells: multiparameter regulation
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, 116024, China
    Hum Cell 29:53-7. 2016
    ....
  5. doi Fabrication and detection of tissue engineered bone aggregates based on encapsulated human ADSCs within hybrid calcium alginate/bone powder gel-beads in a spinner flask
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China Electronic address
    Mater Sci Eng C Mater Biol Appl 62:787-94. 2016
    ..In summary, hybrid gel-beads encapsulating ADSCs are proved to be feasible as a new method to fabricate tissue engineered bone aggregation with potential to treat skeletal injury in the near future...
  6. doi Numberical simulation of fluid flow and three-dimensional expansion of tissue engineering seed cells in large scale inside a novel rotating wall hollow fiber membrane bioreactor
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, 116024, China
    Bioprocess Biosyst Eng 38:1527-40. 2015
    ..Besides, hollow fiber membrane carrier with a diameter of 0.2 mm has an excellent biocompatibility and their radial locations presented a tiny influence on flow field inside the culture chamber. ..
  7. doi In vitro culture and harvest of BMMSCs on the surface of a novel thermosensitive glass microcarrier
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China Electronic address
    Mater Sci Eng C Mater Biol Appl 58:324-30. 2016
    ..More importantly, BMMSCs could be fully removed from the thermosensitive glass microcarriers with remained cell viability. ..
  8. doi Three-dimensional dynamic fabrication of engineered cartilage based on chitosan/gelatin hybrid hydrogel scaffold in a spinner flask with a special designed steel frame
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China Electronic address
    Mater Sci Eng C Mater Biol Appl 55:384-92. 2015
    ....
  9. doi Mass transfer analysis of growth and substance metabolism of NSCs cultured in collagen-based scaffold in vitro
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, 116024, China
    Appl Biochem Biotechnol 174:2114-30. 2014
    ..This study also confirmed that 2-mm thickness of collagen scaffold was capable of in vitro cultivation and growth of NSCs with an inoculating density of 1 × 10(6) cells/mL...
  10. doi Dynamic fabrication of tissue-engineered bone substitutes based on derived cancellous bone scaffold in a spinner flask bioreactor system
    Song Kedong
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, 116024, China
    Appl Biochem Biotechnol 174:1331-43. 2014
    ..It confirmed that three-dimensional dynamic culture in spinner flask promoted ADSC osteogenic differentiation, proliferation, and matrix secretion significantly to make for the fabrication of engineered bone substitutes. ..
  11. doi Preparation, mass diffusion, and biocompatibility analysis of porous-channel controlled calcium-alginate-gelatin hybrid microbeads for in vitro culture of NSCs
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, 116024, China
    Appl Biochem Biotechnol 173:838-50. 2014
    ..This experiment demonstrated that CAG microbeads had good cytocompatibility that made it suitable for the culture and successfully maintained stemness of neural stem cells. ..
  12. doi In vitro culture and oxygen consumption of NSCs in size-controlled neurospheres of Ca-alginate/gelatin microbead
    Kedong Song
    State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China Electronic address
    Mater Sci Eng C Mater Biol Appl 40:197-203. 2014
    ..This study presents an alternative method in hybrid microbead preparation to generate a highly favorable three-dimensional cell carrier for NSCs and was successfully applied for its effective in vitro expansion...
  13. pmc Desmoid tumor of posterior cruciate ligament of the knee: a case report
    Wang Ling
    Department of Oncology, First Affiliated Hospital of Dalian Medical University, Dalian, People s Republic of China
    BMC Musculoskelet Disord 14:69. 2013
    ..They may invade nearby tissues and organs, however, and can be difficult to control. Desmoid tumor in the posterior cruciate ligament (PCL) of the knee has never been described in the literature...
  14. doi Fabrication and evaluation of a sustained-release chitosan-based scaffold embedded with PLGA microspheres
    Kedong Song
    Dalian R and D Center for Stem Cell and Tissue Engineering, State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China
    Mater Sci Eng C Mater Biol Appl 33:1506-13. 2013
    ..44±1.81)×10(-2) mg/mL. This novel chitosan-based scaffold embedded with PLGA microspheres has proven to be a promising technique for the development of new and improved tissue engineering scaffolds...
  15. doi In vitro culture, determination, and directed differentiation of adult adipose-derived stem cells towards cardiomyocyte-like cells induced by angiotensin II
    Kedong Song
    Dalian R and D Center for Stem Cell and Tissue Engineering, State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, 116024, China
    Appl Biochem Biotechnol 170:459-70. 2013
    ..This current study indicated that ADSCs possessed the characteristics of mesenchymal stem cells and angiotensin II could induce ADSCs into cardiomyocyte-like cells...
  16. pmc Numerical simulation of fluid field and in vitro three-dimensional fabrication of tissue-engineered bones in a rotating bioreactor and in vivo implantation for repairing segmental bone defects
    Kedong Song
    Dalian R and D Center for Stem Cell and Tissue Engineering, State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China
    Cell Stress Chaperones 18:193-201. 2013
    ..This study demonstrates that stress stimulation in an RWVB can be beneficial for cell/bio-derived bone constructs fabricated in an RWVB, with an application for repairing segmental bone defects...
  17. doi Investigation of coculture of human adipose-derived stem cells and mature adipocytes
    Kedong Song
    Dalian R and D Center for Stem Cell and Tissue Engineering, State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China
    Appl Biochem Biotechnol 167:2381-7. 2012
    ..These results indicated that hADSCs cocultured with human adult adipocytes could not successfully differentiate into adipocytes...
  18. doi An ICT-based ratiometric probe for hydrazine and its application in live cells
    Jiangli Fan
    State Key Laboratory of Fine Chemicals, Dalian University of Technology, 2 Linggong Road, Dalian 116024, PR China
    Chem Commun (Camb) 48:8117-9. 2012
    ..A ratiometric fluorescence probe that enables rapid, low-limit and naked-eye detection is successfully designed and used for hydrazine determination in live cells...
  19. doi Growth characteristics of human adipose-derived stem cells during long time culture regulated by cyclin a and cyclin D1
    Lili Jiang
    Dalian University of Technology, Environmental and Life Science Building 3 403, No 2 Linggong Road, Ganjingzi District, Dalian 116024, China
    Appl Biochem Biotechnol 168:2230-44. 2012
    ..This study demonstrates that a great quantity of hADSCs can be obtained in vitro by prolonging the culture time of each passage. And cyclin A and cyclin D1 affect the distribution of cell cycle and regulate the growth of hADSCs...
  20. doi Comparison of mesenchymal stem cells released from poly(N-isopropylacrylamide) copolymer film and by trypsinization
    Lei Yang
    Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, People s Republic of China
    Biomed Mater 7:035003. 2012
    ..This indicates that the PNIPAAm copolymer films and their matching cooling treatment can be used as effective alternatives to the existing culture substrates and traditional enzymatic digestion for MSCs...
  21. doi Culture and differentiation of rat neural stem/progenitor cells in a three-dimensional collagen scaffold
    Dan Ge
    Dalian R and D Center for Stem Cell and Tissue Engineering, Chemical Engineering School, Dalian University of Technology, Dalian, 116024, China
    Appl Biochem Biotechnol 170:406-19. 2013
    ..Our 3D neural-like tissue construct was similar to the neural tissue in morphology and cell compositions. They thus have a potential to be used for drug screening, detection of environment toxins, and replacement therapy...
  22. pmc Induced pluripotent stem cells generated from human adipose-derived stem cells using a non-viral polycistronic plasmid in feeder-free conditions
    Xinjian Qu
    Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Liaoning, Dalian, China
    PLoS ONE 7:e48161. 2012
    ..Therefore, this technology provides a platform for studying the biology of iPSCs without viral vectors, and can hopefully overcome immune rejection and ethical concerns, which are the two important barriers of ESC applications...
  23. doi Enhanced fluorescent chemosensor for Ag+ in absolute aqueous solution and living cells: an experimental and theoretical study
    Mingming Hu
    State Key Laboratory of Fine Chemicals, Dalian University of Technology, 2 Linggong Road, 116024 Dalian, China
    Analyst 137:2107-11. 2012
    ..The difference of fluorescence enhancement process after binding with Ag(+)/Hg(2+) in acetonitrile/water solution was first proved by theoretical calculations...
  24. doi Simultaneous expansion and harvest of hematopoietic stem cells and mesenchymal stem cells derived from umbilical cord blood
    Song Kedong
    Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, 116023, China
    J Mater Sci Mater Med 21:3183-93. 2010
    ..It was thus demonstrated that the simultaneous expansion and harvest of UCB-HSCs and UCB-MSCs is possible to be accomplished using a feasible bioreactor culture system such as the RWV bioreactor with the support of GCSC microcarriers...
  25. doi Investigation of the effective action distance between hematopoietic stem/progenitor cells and human adipose-derived stem cells during their in vitro co-culture
    Kedong Song
    Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China
    Appl Biochem Biotechnol 165:776-84. 2011
    ..1 ± 0.2 and 5.0 ± 0.1-fold, respectively. It can therefore be concluded that the optimal action distance between stem cells and their supportive cells, when cultured together for 7 days, is of around 350 μm...
  26. doi Enhancement of adipose-derived stem cell differentiation in scaffolds with IGF-I gene impregnation under dynamic microenvironment
    Yanxia Zhu
    Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, China
    Stem Cells Dev 19:1547-56. 2010
    ..The results would be useful for developing tissue-engineered grafts for myocardial repair...
  27. doi The antitumor effect of mesenchymal stem cells transduced with a lentiviral vector expressing cytosine deaminase in a rat glioma model
    Song Fei
    Department of Neurosurgery, Second Hospital Affiliated to Dalian Medical University, Dalian, 116027, China
    J Cancer Res Clin Oncol 138:347-57. 2012
    ..The purpose of this study was to evaluate the antitumor effect of cytosine deaminase (CD)-expressing MSCs in a rat C6 glioma model...
  28. doi Fluorescent chemodosimeter for Cys/Hcy with a large absorption shift and imaging in living cells
    Mingming Hu
    State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116012, China
    Org Biomol Chem 9:980-3. 2011
    ..The detection mechanism was proved by (1)H NMR, mass spectrometry analysis and Gaussian calculations...
  29. doi Preparation, fabrication and biocompatibility of novel injectable temperature-sensitive chitosan/glycerophosphate/collagen hydrogels
    Kedong Song
    Dalian R and D Center for Stem Cell and Tissue Engineering, State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, China
    J Mater Sci Mater Med 21:2835-42. 2010
    ....