Zi Qiang Meng

Summary

Affiliation: Shanxi University
Country: China

Publications

  1. doi request reprint The vasorelaxant effect and its mechanisms of sodium bisulfite as a sulfur dioxide donor
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Chemosphere 89:579-84. 2012
  2. ncbi request reprint Micronuclei induced by sulfur dioxide inhalation in mouse bone-marrow cells in vivo
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Department of Life Sciences, Shanxi University, Taiyuan, People s Republic of China
    Inhal Toxicol 14:303-9. 2002
  3. ncbi request reprint [Progress in sulfur dioxide biology: from toxicology to physiology]
    Zi Qiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Sheng Li Xue Bao 63:593-600. 2011
  4. doi request reprint Vasodilator effect of gaseous sulfur dioxide and regulation of its level by Ach in rat vascular tissues
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Inhal Toxicol 21:1223-8. 2009
  5. ncbi request reprint The vasodilator effect and its mechanism of sulfur dioxide-derivatives on isolated aortic rings of rats
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan, China
    Inhal Toxicol 19:979-86. 2007
  6. ncbi request reprint Cell morphological ultrastructural changes in various organs from mice exposed by inhalation to sulfur dioxide
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan, China
    Inhal Toxicol 19:543-51. 2007
  7. ncbi request reprint Damage effects of dust storm PM2.5 on DNA in alveolar macrophages and lung cells of rats
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Research Center of Environmental Science and Engineering, Shanxi University, Taiyuan 030006, China
    Food Chem Toxicol 45:1368-74. 2007
  8. ncbi request reprint [Effects of dust storm fine particles instillation on oxidative damage in hearts, livers, lungs of rats]
    Zi Qiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Wei Sheng Yan Jiu 35:690-3. 2006
  9. ncbi request reprint DNA damage in mice treated with sulfur dioxide by inhalation
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan, China
    Environ Mol Mutagen 46:150-5. 2005
  10. ncbi request reprint Levels of sulfite in three organs from mice exposed to sulfur [corrected] dioxide
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan, China
    Inhal Toxicol 17:309-13. 2005

Detail Information

Publications64

  1. doi request reprint The vasorelaxant effect and its mechanisms of sodium bisulfite as a sulfur dioxide donor
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Chemosphere 89:579-84. 2012
    ..These results led to the conclusion that bisulfite (HSO(3)(-)) might be a vasoactive factor and sodium bisulfite can be used as a SO(2) donor for the study of SO(2) biology...
  2. ncbi request reprint Micronuclei induced by sulfur dioxide inhalation in mouse bone-marrow cells in vivo
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Department of Life Sciences, Shanxi University, Taiyuan, People s Republic of China
    Inhal Toxicol 14:303-9. 2002
    ..These results from male and female mice were very similar; no sex difference was observed. These results imply that SO2 is a clastogenic and genotoxic agent...
  3. ncbi request reprint [Progress in sulfur dioxide biology: from toxicology to physiology]
    Zi Qiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Sheng Li Xue Bao 63:593-600. 2011
    ....
  4. doi request reprint Vasodilator effect of gaseous sulfur dioxide and regulation of its level by Ach in rat vascular tissues
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Inhal Toxicol 21:1223-8. 2009
    ..These findings also demonstrate that endogenous SO(2) level in vascular tissue may be regulated by Ach and NE...
  5. ncbi request reprint The vasodilator effect and its mechanism of sulfur dioxide-derivatives on isolated aortic rings of rats
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan, China
    Inhal Toxicol 19:979-86. 2007
    ..The vasorelaxation was at partly related to the increase of prostacyclin (PGI(2)) induced by SO(2) derivatives...
  6. ncbi request reprint Cell morphological ultrastructural changes in various organs from mice exposed by inhalation to sulfur dioxide
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan, China
    Inhal Toxicol 19:543-51. 2007
    ..Thus, inhalation of sulfur dioxide appears to be not only toxic to the respiratory system, but also a systemic toxin as well...
  7. ncbi request reprint Damage effects of dust storm PM2.5 on DNA in alveolar macrophages and lung cells of rats
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Research Center of Environmental Science and Engineering, Shanxi University, Taiyuan 030006, China
    Food Chem Toxicol 45:1368-74. 2007
    ..5 whose airborne mass were much higher. Further studies are needed to determine the components of dust storm particles that may contribute to the particle toxicity...
  8. ncbi request reprint [Effects of dust storm fine particles instillation on oxidative damage in hearts, livers, lungs of rats]
    Zi Qiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Wei Sheng Yan Jiu 35:690-3. 2006
    ..In this study, the effects of dust storm PM2.5 on oxidative damage in three organs of rats were investigated...
  9. ncbi request reprint DNA damage in mice treated with sulfur dioxide by inhalation
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan, China
    Environ Mol Mutagen 46:150-5. 2005
    ..These data also suggest that detecting DNA damage in blood lymphocytes, using the Comet assay, may serve as a useful tool for evaluating the impact of pulmonary SO2 exposure in human biomonitoring studies...
  10. ncbi request reprint Levels of sulfite in three organs from mice exposed to sulfur [corrected] dioxide
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan, China
    Inhal Toxicol 17:309-13. 2005
    ..These results offered a support for the viewpoint that SO(2) is a systemic toxic agent...
  11. ncbi request reprint Effects of sodium metabisulfite on potassium currents in acutely isolated CA1 pyramidal neurons of rat hippocampus
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Research Center of Environmental Science and Engineering, Shanxi University, Wucheng Road 36, Taiyuan 030006, PR China
    Food Chem Toxicol 43:225-32. 2005
    ..These results suggested that SMB differently affected IA and IK, and it would decrease the excitability of hippocampal neuron by increasing potassium currents...
  12. ncbi request reprint DNA damaging effects of sulfur dioxide derivatives in cells from various organs of mice
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Research Center of Environmental Science and Engineering, Shanxi University, Taiyuan 030006, China
    Mutagenesis 19:465-8. 2004
    ..Taken together, these results suggest that SO2 and its derivatives are systemic toxic agents. However, further studies need to be performed before a definitive conclusion can be drawn...
  13. ncbi request reprint Oxidation damage of sulfur dioxide on testicles of mice
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Wucheng Road 36, Taiyuan 030006, PR China
    Environ Res 96:298-304. 2004
    ..Further work is required to understand the toxicological role of SO2 in reproduction organs or even sperm from humans and animals...
  14. ncbi request reprint Effects of hydrogen peroxide on sodium current in acutely isolated rat hippocampal CA1 neurons
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Wucheng Road 36, Taiyuan 030006, PR China
    Toxicol Lett 147:45-52. 2004
    ..However, the steady-state activation curve was not affected. These results indicated that H2O2 could increase the amplitudes of Na+ currents and change the inactivation properties of Na+ channels even in very low concentration...
  15. ncbi request reprint Induction effects of sulfur dioxide inhalation on chromosomal aberrations in mouse bone marrow cells
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Department of Life Sciences, Shanxi University, Taiyuan 030006, People s Republic of China
    Mutagenesis 17:215-7. 2002
    ..Long exposure to SO(2) pollution at low concentrations in the environment may be a potential risk for induction of cytogenetic damage in vivo in humans...
  16. ncbi request reprint [Effects of AlCl3 on transient outward K+ current and delayed rectifier K(+) current in acutely isolated rat hippocampal CA1 neurons]
    Zi Qiang Meng
    Department of Environmental Science and Toxicology, Shanxi University, Taiyuan 030006
    Sheng Li Xue Bao 55:401-4. 2003
    ..These results imply that AlCl3 may damage potassium channel of the hippocampal CA1 neurons from rats and this may be related to the mechanism of the damage to the central nervous system by aluminum...
  17. ncbi request reprint Oxidative damage of sulfur dioxide on various organs of mice: sulfur dioxide is a systemic oxidative damage agent
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Department of Life Sciences, Shanxi University, Taiyuan, People s Republic of China
    Inhal Toxicol 15:181-95. 2003
    ..Further work is required to understand the toxicological role of SO(2) on multiple or even all organs in mammals...
  18. ncbi request reprint Oxidative damage of sulfur dioxide inhalation on stomachs and intestines of mice
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Department of Life Sciences, Shanxi University, Taiyuan, 030006, China
    Inhal Toxicol 15:397-410. 2003
    ..Further work is required to understand toxicological role of SO(2) on multiple or even all organs in human and animal...
  19. ncbi request reprint Blood pressure of rats lowered by sulfur dioxide and its derivatives
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, P R China
    Inhal Toxicol 15:951-9. 2003
    ..2) SO(2) is a systemic toxic agent, not only to the respiratory system. SO(2) can cause at least functional damage to the cardiovascular system...
  20. ncbi request reprint [Effect of SO2 derivatives on sodium currents in acutely isolated rat hippocampal CA1 neurons]
    Zi Qiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Sheng Li Xue Bao 54:267-70. 2002
    ..27+/-4.95 mV (n=10, P<0.01), respectively, but the slope factor was not changed. These results imply that SO2 derivatives have neurotoxic effects and that SO2 pollution is probably related to some diseases of central neuronal system...
  21. ncbi request reprint Effects of sulfur dioxide on the expressions of MUC5AC and ICAM-1 in airway of asthmatic rats
    Ruijin Li
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Regul Toxicol Pharmacol 48:284-91. 2007
    ....
  22. ncbi request reprint Oxidative damage of sulfur dioxide inhalation on lungs and hearts of mice
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Environ Res 93:285-92. 2003
    ..Additional work is required to understand the toxicological role of SO2 on many or even all mammalian organs...
  23. doi request reprint Epigallocatechin-3-gallate protects Na+ channels in rat ventricular myocytes against sulfite
    Haiying Wei
    College of Environmental Science and Resources, Shanxi University, Taiyuan, China
    Cardiovasc Toxicol 10:166-73. 2010
    ..In conclusion, EGCG could protect Na(+) channels in rat ventricular myocytes against the oxidative damage induced by sulfite as a scavenger of the ROS...
  24. ncbi request reprint Effects of airborne fine particulate matter on antioxidant capacity and lipid peroxidation in multiple organs of rats
    Xiaoli Liu
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan, China
    Inhal Toxicol 17:467-73. 2005
    ..Its toxic effects might be attributed to oxidative damage mediated by prooxidant/antioxidant imbalance or excess free radicals. Further work is required to explain the toxicity role of PM(2.5) on multiple organs of mammals...
  25. ncbi request reprint Protein oxidation and DNA-protein crosslink induced by sulfur dioxide in lungs, livers, and hearts from mice
    Jingfang Xie
    College of Environment and Resource, Shanxi University, Taiyuan, China
    Inhal Toxicol 19:759-65. 2007
    ..Our results also indicated the regulation of PCO and that of DPC induced by SO(2) were conformed to each other; this implies that the protein oxidative damage may be associated with the emergence of DPC...
  26. ncbi request reprint Effects of sulfur dioxide on the expressions of EGF, EGFR, and COX-2 in airway of asthmatic rats
    Ruijin Li
    Research Center of Environmental Science and Engineering and Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan, 030006, China
    Arch Environ Contam Toxicol 54:748-57. 2008
    ....
  27. ncbi request reprint Effects of derivatives of sulfur dioxide on transient outward potassium currents in acutely isolated hippocampal neurons
    Zhengqing Du
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, PR China
    Food Chem Toxicol 42:1211-6. 2004
    ..SO2 derivatives increased the maximal conductance and delayed the inactivation process of TOCS. These results suggest that SO2 derivatives would increase the excitability of hippocampal neurons...
  28. doi request reprint Expression of oncogenes and tumor suppressor genes in lungs of rats exposed to sulfur dioxide and benzo(a)pyrene
    Guohua Qin
    Institute of Environmental Medicine and Toxicology, Research Center of Environmental Science and Engineering, Shanxi University, Taiyuan, China
    Inhal Toxicol 22:322-9. 2010
    ..Elucidating the expression patterns of those factors after SO(2) and B(a)P exposure may be critical to understanding the mechanisms of SO(2) cocarcinogenesis and helpful for therapeutic intervention...
  29. ncbi request reprint Sulfur dioxide derivative modulation of potassium channels in rat ventricular myocytes
    Aifang Nie
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, PR China
    Arch Biochem Biophys 442:187-95. 2005
    ....
  30. doi request reprint Effect of sulfur dioxide on expression of proto-oncogenes and tumor suppressor genes from rats
    Juli Bai
    Institute of Environmental Medicine and Toxicology, Research Center of Environmental Science and Engineering, Shanxi University, Taiyuan, China
    Environ Toxicol 25:272-83. 2010
    ..Understanding its molecular controls will benefit development of treatments for many diseases...
  31. ncbi request reprint Modulation of sodium currents in rat dorsal root ganglion neurons by sulfur dioxide derivatives
    Zhengqing Du
    Institute of Environmental Medicine and Toxicology, Shanxi University, Wucheng Road 36, Taiyuan, Shanxi 030006, PR China
    Brain Res 1010:127-33. 2004
    ..The results suggest that SO2 derivatives would increase the excitability of neurons and alter the ion selectivity for two types of sodium currents...
  32. ncbi request reprint [Blockade of magnesium sulfate on transient outward K+ current and delayed rectifier K+ current in acutely isolated rat hippocampal neurons]
    Nan Sang
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Yao Xue Xue Bao 37:510-5. 2002
    ..To study the effect of magnesium sulfate on transient outward K+ current (IA) and delayed rectifier K+ current (IK) in freshly dissociated hippocampal neurons of rats...
  33. ncbi request reprint Study of the interaction of sulfur dioxide derivative with cardiac sodium channel
    Aifang Nie
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Biochim Biophys Acta 1718:67-73. 2005
    ..These results indicated that SO(2) derivatives produced concentration-dependent stimulation of cardiac sodium channels, which due mainly to the interaction of the drug with sodium channels in the inactivated state...
  34. ncbi request reprint Effect of sulfur dioxide inhalation on CYP1A1 and CYP1A2 in rat liver and lung
    Guohua Qin
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Toxicol Lett 160:34-42. 2005
    ..Reduction of hepatic and pulmonary CYPlAl and lA2 expression during SO2 exposure may be part of an adaptive response by the liver and lung to minimize cell damage...
  35. doi request reprint Expression of caspase and apoptotic signal pathway induced by sulfur dioxide
    Juli Bai
    Institute of Environmental Medicine and Toxicology, Research Center of Environmental Science and Engineering, Shanxi University, Taiyuan 030006, China
    Environ Mol Mutagen 51:112-22. 2010
    ..These results suggest that SO(2) exposure increases the expression and activity of both initiator and and effector caspases, and may induce apoptosis in liver and lung of rats through both death receptor and mitochondrial pathways...
  36. doi request reprint The vasodilator mechanism of sulfur dioxide on isolated aortic rings of rats: Involvement of the K+ and Ca2+ channels
    Quanxi Zhang
    Institute of Environmental Medicine and Toxicology, Research Center of Environmental Science and Engineering, Shanxi University, Wucheng Road 92, Taiyuan 030006, Shanxi Province, PR China
    Eur J Pharmacol 602:117-23. 2009
    ....
  37. ncbi request reprint Effects of SO2 derivatives on expressions of MUC5AC and IL-13 in human bronchial epithelial cells
    Ruijin Li
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Arch Toxicol 81:867-74. 2007
    ..This might be one of the possible mechanisms that SO2 aggravates asthma disease...
  38. ncbi request reprint Blockade by magnesium of sodium currents in acutely isolated hippocampal CA1 neurons of rat
    Nan Sang
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, PR China
    Brain Res 952:218-21. 2002
    ..These results suggested that blockade of MgSO(4) on Na(+) currents might be an interpretation for its neuroprotection against damages induced by ischemia and oxygen deprivation...
  39. ncbi request reprint [Effect of SO2 inhalation on the levels of GSH and GSH/GSSG in 9 organs of mice]
    Hong Geng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Wei Sheng Yan Jiu 32:103-6. 2003
    ..The decline of the GSH level and GSH/GSSH ratio suggests that the toxic effect of SO2 is associated with its lowering the levels of antioxidants and weakening the defense system and antioxidation in organisms...
  40. ncbi request reprint Effect of sulfur dioxide inhalation on CYP2B1/2 and CYP2E1 in rat liver and lung
    Guohua Qin
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan, China
    Inhal Toxicol 18:581-8. 2006
    ....
  41. ncbi request reprint In vitro responses of rat alveolar macrophages to particle suspensions and water-soluble components of dust storm PM(2.5)
    Hong Geng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, PR China
    Toxicol In Vitro 20:575-84. 2006
    ..But due to a higher concentration of airborne PM(2.5) mass concentration in dust storm days than that in normal days, it concluded that during dust storm episodes, a much more serious effect on AM was imminent...
  42. ncbi request reprint Modulation of L-type calcium current in rat cardiac myocytes by sulfur dioxide derivatives
    Aifang Nie
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan, China
    Food Chem Toxicol 44:355-63. 2006
    ..These results suggested that SO(2) inhalation might cause cardiac myocyte injury through increasing intracellular calcium via voltage-gated calcium channels...
  43. ncbi request reprint [Sulfur dioxide-induced liver pathology]
    Jian Ying Bai
    Institute of Environmental Medicine and Toxicology, School of Life Science and Technology, Shanxi University, Taiyuan 030006, China
    Zhonghua Bing Li Xue Za Zhi 33:155-7. 2004
    ..To investigate effects of short-term sulfur dioxide inhalation to the liver...
  44. doi request reprint Effects of sulfur dioxide on expressions of p53, bax and bcl-2 in lungs of asthmatic rats
    Jingfang Xie
    Shanxi University, Taiyuan, China
    Inhal Toxicol 21:952-7. 2009
    ..The regulation mechanism of apoptosis in asthma disease exposure to SO(2) needs further study...
  45. ncbi request reprint Sulfur dioxide derivatives modulation of high-threshold calcium currents in rat dorsal root ganglion neurons
    Zhengqing Du
    Shanxi University of Finance and Economics, Taiyuan 030006, PR China
    Neurosci Lett 405:147-52. 2006
    ..These results indicated a possible correlation between the change of calcium channels and SO(2) inhalation toxicity, which might cause periphery neurons abnormal regulation of nociceptive transmission via calcium channels...
  46. ncbi request reprint Effects of sulfur dioxide derivatives on four asthma-related gene expressions in human bronchial epithelial cells
    Ruijin Li
    Research Center of Environmental Science and Engineering, Shanxi University, Taiyuan 030006, China
    Toxicol Lett 175:71-81. 2007
    ..This might be one of the possible mechanisms that SO(2) aggravates asthma disease...
  47. doi request reprint Enhancing effects of diethyldithiocarbamate on increase of sodium channel by sulfur dioxide derivatives in ventricular myocytes
    Haiying Wei
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, PR China
    Cell Biol Int 32:1143-9. 2008
    ..These results indicated that DDC could enhance the increasing effects on Na+ channels induced by SO2 derivatives, and suggested that the toxicity of SO2 on ventricular myocytes of rats was realized by free radical, especially O2-...
  48. ncbi request reprint Effect of sulfur dioxide inhalation on the glutathione redox system in mice and protective role of sea buckthorn seed oil
    Dongmei Wu
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan, 030006, PR China
    Arch Environ Contam Toxicol 45:423-8. 2003
    ..05). The observations showed that SO2 inhalation resulted in a significant change in the glutathione redox system and indicated that sea buckthorn seed oil could contribute to the antioxidant effects in the case of SO2 exposure...
  49. ncbi request reprint Induction of chromosome aberrations in cultured human lymphocytes treated with sand dust storm fine particles (PM2.5)
    Aili Wei
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, PR China
    Toxicol Lett 166:37-43. 2006
    ..05), but the treatment results of sand dust storm PM2.5 (include its all extract) was not significant different between the cities (P>0.05)...
  50. ncbi request reprint The expressions of protooncogenes and CYP1A in lungs of rats exposed to sulfur dioxide and benzo(a)pyrene
    Guohua Qin
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Regul Toxicol Pharmacol 45:36-43. 2006
    ....
  51. ncbi request reprint Effects of sulfur dioxide on apoptosis-related gene expressions in lungs from rats
    Juli Bai
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Regul Toxicol Pharmacol 43:272-9. 2005
    ..Elucidating the expression patterns of those factors after SO2 inhalation may be critical to our understanding mechanisms of SO2 toxicity and helpful for the therapeutic intervention...
  52. ncbi request reprint Effects of blowing sand fine particles on plasma membrane permeability and fluidity, and intracellular calcium levels of rat alveolar macrophages
    Hong Geng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Wucheng Road 36, Taiyuan 030006, PR China
    Toxicol Lett 157:129-37. 2005
    ..5 on AMs were only relative to treatment dosages but not to dust types, suggesting the blowing sand PM2.5 whose airborne mass concentrations were much higher should be more harmful...
  53. ncbi request reprint Expression of apoptosis-related genes in livers from rats exposed to sulfur dioxide
    Juli Bai
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Toxicology 216:253-60. 2005
    ..It is critical for our understanding of the mechanisms of SO2 toxicity and helpful for the therapeutic intervention to elucidate the expression pattern of those factors involved in apoptosis signaling pathway after SO2 inhalation...
  54. ncbi request reprint [Effects of sulfur dioxide on mRNA expression and activities of hepatic and pulmonary cytochrome P4502B1 and 2E1 in rats]
    Guo Hua Qin
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Wei Sheng Yan Jiu 35:554-6. 2006
    ..To study the effects of sulfur dioxide (SO2) on activities and mRNA expression of hepatic and pulmonary cytochrome P4502B1 and 2E1 in rats...
  55. doi request reprint Sulfur dioxide and benzo(a)pyrene modulates CYP1A and tumor-related gene expression in rat liver
    Guohua Qin
    Institute of Environmental Medicine and Toxicology, Research Center of Environmental Science and Engineering, Shanxi University, Taiyuan 030006, China
    Environ Toxicol 25:169-79. 2010
    ..Although the gene products we studied are classed as oncogenes and tumor suppressor genes, their functions actually relate to more general processes of control of cell proliferation, survival, and/or apoptosis...
  56. ncbi request reprint Genotoxicity of hydrated sulfur dioxide on root tips of Allium sativum and Vicia faba
    Huilan Yi
    Institute of Environmental Medicine and Toxicology, School of Life Sciences and Technology, Shanxi University, 030006, Taiyuan, China
    Mutat Res 537:109-14. 2003
    ..Results of the present study suggest that the Vicia and Allium cytogenetic bioassays are efficient, simple and reproducible in genotoxicity studies of bisulfite...
  57. ncbi request reprint [Inhalation of sulfur dioxide on the DNA damage of brain cells in mice]
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Department of Life Sciences, Shanxi University, Taiyuan 030006, China
    Zhonghua Yu Fang Yi Xue Za Zhi 36:370-3. 2002
    ..To investigate the inhalation of sulfur dioxide (SO(2)) on the DNA damage of brain cells in mammalian animals...
  58. ncbi request reprint [Induction effects of sulfur dioxide inhalation on chromosomal aberrations in mouse bone marrow cells]
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Department of Life Sciences, Shanxi University, Taiyuan 030006, China
    Zhonghua Yu Fang Yi Xue Za Zhi 36:229-31. 2002
    ..To investigate the induction effects of sulfur dioxide (SO(2)) inhalation on chromosomal aberrations (CA) in mouse bone marrow cells...
  59. doi request reprint Effects of sulfur dioxide derivatives on expression of oncogenes and tumor suppressor genes in human bronchial epithelial cells
    Guohua Qin
    Institute of Environmental Medicine and Toxicology, Research Center of Environmental Science and Engineering, Shanxi University, Taiyuan, China
    Food Chem Toxicol 47:734-44. 2009
    ..The data support the hypothesis that SO(2) derivatives could cause the activation of proto-oncogenes and inactivation of tumor suppressor genes and SO(2) derivatives may play a role in the pathogenesis of SO(2)-associated lung cancer...
  60. doi request reprint The role of sulfur dioxide as an endogenous gaseous vasoactive factor in synergy with nitric oxide
    Junling Li
    Institute of Environmental Medicine and Toxicology, Research Center of Environmental Science and Engineering, Shanxi University, Taiyuan 030006, China
    Nitric Oxide 20:166-74. 2009
    ..These findings led to the conclusions: endogenous gaseous SO(2) was a vasoactive factor, which might regulate vascular smooth muscle tone in synergy with NO...
  61. ncbi request reprint Vasodilatation of sulfur dioxide derivatives and signal transduction
    Ziqiang Meng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006, China
    Arch Biochem Biophys 467:291-6. 2007
    ..These results led to the conclusions that SO(2) derivatives might cause the endothelium-independent vasorelaxation effect, and the vasorelaxation was mediated in partly by the signal transduction pathway of PGI(2)-AC-cAMP-PKA...
  62. ncbi request reprint Inhibition of superoxide dismutase, Vitamin C and glutathione on chemiluminescence produced by luminol and the mixture of sulfite and bisulfite
    Hong Geng
    Institute of Environmental Medicine and Toxicology, Shanxi University, Wucheng Road, Taiyuan 030006, PR China
    Spectrochim Acta A Mol Biomol Spectrosc 64:87-92. 2006
    ....
  63. ncbi request reprint [Micronuclei induced by chronic inhalation of SO2 in mouse bone marrow cells]
    Ziqiang Meng
    Institute of Environmental and Toxicology, Department of Life Sciences, Shanxi University, Taiyuan 030006
    Huan Jing Ke Xue 23:123-5. 2002
    ..These results furtherly confirm that SO2 inhalation was a clastogenic and genotoxic agent to mammalian cells, and the combined effects of SO2 and other mutagens are complex...
  64. ncbi request reprint [Study of toxicity on male reproductive system of mice induced by SO2 inhalation]
    Bo Zhang
    The Biology Department of College of Arts and Sciences of Beijing Union Unversity, Beijing 100083, China
    Wei Sheng Yan Jiu 34:167-9. 2005
    ..In this paper, toxicity of SO2 on male reproductive system of mice was studied...