Dongfeng Chen

Summary

Affiliation: Sun Yat-sen University
Country: China

Publications

  1. doi request reprint Two phenolic antioxidants in Suoyang enhance viability of •OH-damaged mesenchymal stem cells: comparison and mechanistic chemistry
    Yulu Xie
    School of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuan East Road No 232, Guangzhou Higher Education Mega Center, Guangzhou, 510006, China
    Chem Cent J 11:84. 2017
  2. pmc Sarcandra glabra (Caoshanhu) protects mesenchymal stem cells from oxidative stress: a bioevaluation and mechanistic chemistry
    Jingjing Liu
    School of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuan East Road No 232, Guangzhou Higher Education Mega Center, 510006, Guangzhou, China
    BMC Complement Altern Med 16:423. 2016
  3. doi request reprint Lyophilized aqueous extracts of Mori Fructus and Mori Ramulus protect Mesenchymal stem cells from •OH-treated damage: bioassay and antioxidant mechanism
    Qian Jiang
    School of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuan East Road No 232, Guangzhou Higher Education Mega Center, Guangzhou, 510006, China
    BMC Complement Altern Med 17:242. 2017
  4. pmc XingNaoJing, prescription of traditional Chinese medicine, prevents autophagy in experimental stroke by repressing p53-DRAM pathway
    Gang Wei
    Research and Development of New Drugs, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China
    BMC Complement Altern Med 15:377. 2015
  5. doi request reprint BMP-Id pathway targeted by cholesterol myristate suppresses the apoptosis of PC12 cells
    Dong Feng Chen
    The State Key Laboratory of Pharmaceutical Biotechnology, Department of Biochemistry, Nanjing University, Nanjing, China
    Brain Res 1367:33-42. 2011
  6. ncbi request reprint [Osteogenesis characteristics of cultured rat mesenchymal stem cells under bone induction condition]
    Dong Feng Chen
    Department of Anatomy, Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong Province 510405, China
    Zhong Xi Yi Jie He Xue Bao 2:375-8. 2004
  7. doi request reprint (+)-Cholesten-3-one induces differentiation of neural stem cells into dopaminergic neurons through BMP signaling
    Dong Feng Chen
    The State Key Laboratory of Pharmaceutical Biotechnology, Department of Biochemistry, Nanjing University, Nanjing, China
    Neurosci Res 68:176-84. 2010
  8. doi request reprint Cholesterol myristate suppresses the apoptosis of mesenchymal stem cells via upregulation of inhibitor of differentiation
    Dong Feng Chen
    The State Key Laboratory of Pharmaceutical Biotechnology, Department of Biochemistry, Nanjing University, Nanjing, China
    Steroids 75:1119-26. 2010
  9. doi request reprint Hexadecanoic acid from Buzhong Yiqi decoction induced proliferation of bone marrow mesenchymal stem cells
    Dong Feng Chen
    The State Key Laboratory of Pharmaceutical Biotechnology, Department of Biochemistry, Nanjing University, Nanjing, China
    J Med Food 13:967-70. 2010
  10. doi request reprint Autocrine BMP4 signaling involves effect of cholesterol myristate on proliferation of mesenchymal stem cells
    Dong Feng Chen
    Department of Anatomy, Guangzhou University of Traditional Chinese Medicine, No 12 Jichang Road, Guangzhou, China
    Steroids 74:1066-72. 2009

Collaborators

Detail Information

Publications18

  1. doi request reprint Two phenolic antioxidants in Suoyang enhance viability of •OH-damaged mesenchymal stem cells: comparison and mechanistic chemistry
    Yulu Xie
    School of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuan East Road No 232, Guangzhou Higher Education Mega Center, Guangzhou, 510006, China
    Chem Cent J 11:84. 2017
    ..The present study attempted to investigate the protective effect of phenolic antioxidants in Suoyang towards •OH-mediated MSCs and then further discusses the chemical mechanisms...
  2. pmc Sarcandra glabra (Caoshanhu) protects mesenchymal stem cells from oxidative stress: a bioevaluation and mechanistic chemistry
    Jingjing Liu
    School of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuan East Road No 232, Guangzhou Higher Education Mega Center, 510006, Guangzhou, China
    BMC Complement Altern Med 16:423. 2016
    ..The present work evaluated its protective effect on mesenchymal stem cells (MSCs) from oxidative stress and then discussed possible mechanisms underlying this observation...
  3. doi request reprint Lyophilized aqueous extracts of Mori Fructus and Mori Ramulus protect Mesenchymal stem cells from •OH-treated damage: bioassay and antioxidant mechanism
    Qian Jiang
    School of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuan East Road No 232, Guangzhou Higher Education Mega Center, Guangzhou, 510006, China
    BMC Complement Altern Med 17:242. 2017
    ..Mori Fructus and Mori Ramulus are two traditional Chinese herbal medicines from mulberries. The present work explores their beneficial effects on •OH-treated mesenchymal stem cells (MSCs) and discusses possible mechanisms...
  4. pmc XingNaoJing, prescription of traditional Chinese medicine, prevents autophagy in experimental stroke by repressing p53-DRAM pathway
    Gang Wei
    Research and Development of New Drugs, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China
    BMC Complement Altern Med 15:377. 2015
    ..Here, we used the cell models of autophagy induced by serum-free condition and ischemia stroke in rats to further investigate whether the p53-DRAM pathway is involved in the effects of XNJ on autophagy...
  5. doi request reprint BMP-Id pathway targeted by cholesterol myristate suppresses the apoptosis of PC12 cells
    Dong Feng Chen
    The State Key Laboratory of Pharmaceutical Biotechnology, Department of Biochemistry, Nanjing University, Nanjing, China
    Brain Res 1367:33-42. 2011
    ..Our findings are therefore of considerable therapeutic significance and provide the potential of newly exploiting cholesterol myristate and clinically in brain disease therapies...
  6. ncbi request reprint [Osteogenesis characteristics of cultured rat mesenchymal stem cells under bone induction condition]
    Dong Feng Chen
    Department of Anatomy, Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong Province 510405, China
    Zhong Xi Yi Jie He Xue Bao 2:375-8. 2004
    ..To investigate the osteogenesis characteristics of cultured rat mesenchymal stem cells (MSCs) under bone induction condition...
  7. doi request reprint (+)-Cholesten-3-one induces differentiation of neural stem cells into dopaminergic neurons through BMP signaling
    Dong Feng Chen
    The State Key Laboratory of Pharmaceutical Biotechnology, Department of Biochemistry, Nanjing University, Nanjing, China
    Neurosci Res 68:176-84. 2010
    ..These findings may contribute to efficient production of dopaminergic neurons from NSCs culture for many applications and raise interesting questions about the role of (+)-Cholesten-3-one in neurogenesis...
  8. doi request reprint Cholesterol myristate suppresses the apoptosis of mesenchymal stem cells via upregulation of inhibitor of differentiation
    Dong Feng Chen
    The State Key Laboratory of Pharmaceutical Biotechnology, Department of Biochemistry, Nanjing University, Nanjing, China
    Steroids 75:1119-26. 2010
    ..These findings can be applied for improving MSCs survival in stem-cell transplantation, bone-marrow transplantation, treatment of bone diseases such as osteoporosis and chemotherapy...
  9. doi request reprint Hexadecanoic acid from Buzhong Yiqi decoction induced proliferation of bone marrow mesenchymal stem cells
    Dong Feng Chen
    The State Key Laboratory of Pharmaceutical Biotechnology, Department of Biochemistry, Nanjing University, Nanjing, China
    J Med Food 13:967-70. 2010
    ..Our findings have now allowed for a refinement in our understanding of TCM with respect to pharmacological regulation of stem cells and may be useful to stem cell biology and therapy...
  10. doi request reprint Autocrine BMP4 signaling involves effect of cholesterol myristate on proliferation of mesenchymal stem cells
    Dong Feng Chen
    Department of Anatomy, Guangzhou University of Traditional Chinese Medicine, No 12 Jichang Road, Guangzhou, China
    Steroids 74:1066-72. 2009
    ..Thus, this study is to provide evidence that autocrine BMP4 signaling involves effect of cholesterol myristate on MSCs proliferation...
  11. ncbi request reprint Extracts from Plastrum testudinis promote proliferation of rat bone-marrow-derived mesenchymal stem cells
    D F Chen
    Department of Anatomy, Guangzhou University of Traditional Chinese Medicine, Guangzhou, China
    Cell Prolif 40:196-212. 2007
    ..The purpose of this study is to identify active components of PT involved in promoting proliferation of MSCs and to investigate its mechanism. PT was extracted with petroleum ether, ethyl acetate, ethanol and water respectively...
  12. ncbi request reprint [Effect of Niupo Zhibao Pellet on expression of neuronal nitric oxide synthase in brain of endotoxin-induced shock rats]
    Jian hong Zhou
    Department of Anatomy, Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong Province 510405, China
    Zhong Xi Yi Jie He Xue Bao 3:115-8. 2005
    ..To investigate the effect of Niupo Zhibao Pellet (NPZBP) on the expression of neuronal nitric oxide synthase (nNOS) in the brain of endotoxin-induced shock rats...
  13. pmc Antioxidant activity and mechanism of Rhizoma Cimicifugae
    Xican Li
    School of Chinese Herbal Medicine, Guangzhou Higher Education Mega Center, Guangzhou University of Chinese Medicine, Waihuang East Road No, 232, Guangzhou 510006, China
    Chem Cent J 6:140. 2012
    ..However, its antioxidant activity has not been reported so far. The aim of the present study was to systematically evaluate the antioxidant ability of RC in vitro, then discuss the mechanism...
  14. doi request reprint Paeonol Inhibits Lipopolysaccharide-Induced HMGB1 Translocation from the Nucleus to the Cytoplasm in RAW264.7 Cells
    Hang Lei
    Laboratory of Molecular Medicine, School of Basic Medicine, Guangzhou University of Chinese Medicine, 232 Waihuandong Road, Guangzhou University Town, Guangzhou, 510006, China
    Inflammation 39:1177-87. 2016
    ..These results indicate that paeonol has the potential to be developed as a novel HMGB1-targeting therapeutic drug for the treatment of inflammatory diseases. ..
  15. doi request reprint Concordance between antioxidant activities in vitro and chemical components of Radix Astragali (Huangqi)
    Xican Li
    School of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China
    Nat Prod Res 26:1050-3. 2012
    ..This large difference clearly demonstrates that the antioxidant effects of RA in vitro might be generally considered to be a result of the presence of phenolic compounds (including flavonoids) but not astragalosides and polysaccharides...
  16. doi request reprint Histological changes of an injectable rhBMP-2/calcium phosphate cement in vertebroplasty of rhesus monkey
    Bo Bai
    Department of Orthopaedic Surgery, The First Affiliated Hospital of Guangzhou Medical College, 151 Yanjing Road, Guangzhou, China
    Spine (Phila Pa 1976) 34:1887-92. 2009
    ..A histologic study of recombinant human bone morphogenetic protein-2/calcium phosphate cement (rhBMP-2/CPC) using adult rhesus monkeys in vivo...
  17. ncbi request reprint Evaluation of antioxidant activity of isoferulic acid in vitro
    Xiaozhen Wang
    School of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China
    Nat Prod Commun 6:1285-8. 2011
    ..Comparison with the IC50 values with those of the positive controls, Trolox and butylated hydroxyanisole (BHA), it can be concluded that isoferulic acid is an effective natural antioxidant in both lipid and aqueous media...
  18. doi request reprint Rapid pulmonary fibrosis induced by acute lung injury via a lipopolysaccharide three-hit regimen
    Hui Li
    Department of Anatomy, Guangzhou University of Chinese Medicine, Guangzhou, People s Republic of China
    Innate Immun 15:143-54. 2009
    ..The investigation was not only performed to establish a new rapid pulmonary fibrosis model, but also to provide the elicitation for mechanism of ALI changed into the rapid pulmonary fibrosis...