J Mokry

Summary

Affiliation: Charles University
Country: Czech Republic

Publications

  1. ncbi request reprint Cerebral angiogenesis shows nestin expression in endothelial cells
    J Mokry
    Department of Histology and Embryology, Charles University, Medical Faculty, Hradec Kralove, Czech Republic
    Gen Physiol Biophys 18:25-9. 1999
  2. pmc Telomere attrition occurs during ex vivo expansion of human dental pulp stem cells
    Jaroslav Mokry
    Department of Histology and Embryology, Faculty of Medicine in Hradec Kralove, Charles University in Prague, Simkova 870, 50038 Hradec Kralove, Czech Republic
    J Biomed Biotechnol 2010:673513. 2010
  3. ncbi request reprint Expression of intermediate filament nestin in blood vessels of neural and non-neural tissues
    Jaroslav Mokry
    Charles University in Prague, Faculty of Medicine and University Hospital Hradec Kralove, Department of Histology and Embryology, Czech Republic
    Acta Medica (Hradec Kralove) 51:173-9. 2008
  4. doi request reprint Re-expression of nestin in the myocardium of postinfarcted patients
    J Mokry
    Department of Histology and Embryology, Medical Faculty in Hradec Kralove, Charles University in Prague, Hradec Kralove, Czech Republic
    Virchows Arch 453:33-41. 2008
  5. doi request reprint Phenotypic and morphological characterization of in vitro oligodendrogliogenesis
    J Mokry
    Department of Histology and Embryology, Charles University in Prague, Faculty of Medicine in Hradec Kralove, 50038 Hradec Kralove, Czech Republic
    Stem Cells Dev 17:333-41. 2008
  6. ncbi request reprint Differentiation of neural stem cells into cells of oligodendroglial lineage
    Jaroslav Mokry
    Charles University in Prague, Faculty of Medicine in Hradec Kralove, Department of Histology and Embryology, Czech Republic
    Acta Medica (Hradec Kralove) 50:35-41. 2007
  7. ncbi request reprint Foetal mouse neural stem cells give rise to ependymal cells in vitro
    J Mokry
    Department of Histology and Embryology, Faculty of Medicine in Hradec Kralove, Charles University in Prague, Czech Republic
    Folia Biol (Praha) 52:149-55. 2006
  8. ncbi request reprint Subependymal zone: immunohistochemically distinct compartment in the adult mammalian forebrain
    Jaroslav Mokry
    Charles University in Prague, Faculty of Medicine in Hradec Kralove, Czech Republic
    Acta Medica (Hradec Kralove) 47:235-42. 2004
  9. ncbi request reprint Biocompatibility of HEMA copolymers designed for treatment of CNS diseases with polymer-encapsulated cells
    J Mokry
    Department of Histology and Embryology, Faculty of Medicine, Charles University, 50001 Hradec Kralove, Czech Republic
    Biotechnol Prog 16:897-904. 2000
  10. ncbi request reprint Differentiation potential of murine neural stem cells in vitro and after transplantation
    J Mokry
    Department of Histology and Embryology, Charles University in Prague, Medical Faculty in Hradec Kralove, Czech Republic
    Transplant Proc 37:268-72. 2005

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Cerebral angiogenesis shows nestin expression in endothelial cells
    J Mokry
    Department of Histology and Embryology, Charles University, Medical Faculty, Hradec Kralove, Czech Republic
    Gen Physiol Biophys 18:25-9. 1999
    ..Our results demonstrate that nestin expression in endothelial cells lining cerebral vessels accompanies the process of angiogenesis...
  2. pmc Telomere attrition occurs during ex vivo expansion of human dental pulp stem cells
    Jaroslav Mokry
    Department of Histology and Embryology, Faculty of Medicine in Hradec Kralove, Charles University in Prague, Simkova 870, 50038 Hradec Kralove, Czech Republic
    J Biomed Biotechnol 2010:673513. 2010
    ....
  3. ncbi request reprint Expression of intermediate filament nestin in blood vessels of neural and non-neural tissues
    Jaroslav Mokry
    Charles University in Prague, Faculty of Medicine and University Hospital Hradec Kralove, Department of Histology and Embryology, Czech Republic
    Acta Medica (Hradec Kralove) 51:173-9. 2008
    ..Elevation of nestin expression likely corresponds to reorganization of intermediate filament network in the cytoskeleton of endothelial cells in the course of their maturation or adaptation to changes in growing tissues...
  4. doi request reprint Re-expression of nestin in the myocardium of postinfarcted patients
    J Mokry
    Department of Histology and Embryology, Medical Faculty in Hradec Kralove, Charles University in Prague, Hradec Kralove, Czech Republic
    Virchows Arch 453:33-41. 2008
    ..These findings document a crucial role of nestin in remodeling cytoskeleton of cells in the human postinfarcted myocardium...
  5. doi request reprint Phenotypic and morphological characterization of in vitro oligodendrogliogenesis
    J Mokry
    Department of Histology and Embryology, Charles University in Prague, Faculty of Medicine in Hradec Kralove, 50038 Hradec Kralove, Czech Republic
    Stem Cells Dev 17:333-41. 2008
    ..These include oligodendrocyte progenitors, preoligodendrocytes, and oligodendrocytes. The highly complex morphology of mature oligodendrocytes was compatible with functional cells...
  6. ncbi request reprint Differentiation of neural stem cells into cells of oligodendroglial lineage
    Jaroslav Mokry
    Charles University in Prague, Faculty of Medicine in Hradec Kralove, Department of Histology and Embryology, Czech Republic
    Acta Medica (Hradec Kralove) 50:35-41. 2007
    ..The cultivation conditions that supported growth and differentiation of neural stem cells were optimal for in vitro developmental studies and the production of oligodendroglial cells...
  7. ncbi request reprint Foetal mouse neural stem cells give rise to ependymal cells in vitro
    J Mokry
    Department of Histology and Embryology, Faculty of Medicine in Hradec Kralove, Charles University in Prague, Czech Republic
    Folia Biol (Praha) 52:149-55. 2006
    ..Confocal microscopy confirmed the presence of alpha-tubulin-immunoreactive cilia arranged in tufts located on the apical surface of epitheloid cells. Our data indicate that ependymal cells are spontaneously derived from NSCs...
  8. ncbi request reprint Subependymal zone: immunohistochemically distinct compartment in the adult mammalian forebrain
    Jaroslav Mokry
    Charles University in Prague, Faculty of Medicine in Hradec Kralove, Czech Republic
    Acta Medica (Hradec Kralove) 47:235-42. 2004
    ....
  9. ncbi request reprint Biocompatibility of HEMA copolymers designed for treatment of CNS diseases with polymer-encapsulated cells
    J Mokry
    Department of Histology and Embryology, Faculty of Medicine, Charles University, 50001 Hradec Kralove, Czech Republic
    Biotechnol Prog 16:897-904. 2000
    ..The amount of connective tissue components surrounding the implanted microcapsules increased only slightly. These findings indicated that p(HEMA-co-EMA) hydrogel was well tolerated after implantation in the brain...
  10. ncbi request reprint Differentiation potential of murine neural stem cells in vitro and after transplantation
    J Mokry
    Department of Histology and Embryology, Charles University in Prague, Medical Faculty in Hradec Kralove, Czech Republic
    Transplant Proc 37:268-72. 2005
    ..Following intravenous injection of NSCs, the transplanted cells colonized hematopoietic and lymphatic organs, facilitating hematopoiesis in irradiated animals...
  11. ncbi request reprint Nestin expression by newly formed human blood vessels
    J Mokry
    Department of Histology and Embryology, Charles University in Prague, Medical Faculty in Hradec Kralove, Czech Republic
    Stem Cells Dev 13:658-64. 2004
    ..Because nestin expression was recognized under all conditions of vascular development, nestin represents a novel and reliable marker of neovascularization...
  12. ncbi request reprint Experimental brain injury induces activation of neural stem cells in the forebrain subependyma
    Jaroslav Mokry
    Department of Histology and Embryology, Charles University Medical Faculty, Hradec Kralove, Czech Republic
    Appl Immunohistochem Mol Morphol 11:161-7. 2003
    ..Our data suggest that each type of brain injury induces a SEZ proliferative response with a specific temporal pattern...
  13. ncbi request reprint Angiogenesis of extra- and intraembryonic blood vessels is associated with expression of nestin in endothelial cells
    J Mokry
    Department of Histology and Embryology, Medical Faculty, Charles Uniiersity, Hradec Kralove, Czech Republic
    Folia Biol (Praha) 44:155-61. 1998
    ..The strongest positive signal was given by the endothelium of newly vascularized tissues. In contrast to the developing tissues, expression of nestin by vascular endothelial cells was greatly reduced in adult tissues...
  14. ncbi request reprint Mitoxantrone ability to induce premature senescence in human dental pulp stem cells and human dermal fibroblasts
    M Seifrtov√°
    Department of Medical Biochemistry, Faculty of Medicine in Hradec Kralove, Charles University in Prague, Czech Republic
    J Physiol Pharmacol 64:255-66. 2013
    ..MTX provokes the activation of p53-p21(WAF1/Cip1) pathway in both cell types and activates cell-cycle inhibitor p16(INK4a) in HDFs, but not in DPSCs. Higher concentrations of MTX induced caspase-mediated apoptosis...
  15. ncbi request reprint Ionizing radiation induces senescence and differentiation of human dental pulp stem cells
    R Havelek
    Faculty of Medicine in Hradec Kralove, Charles University in Prague, Department of Medical Biochemistry, Hradec Kralove, Czech Republic
    Folia Biol (Praha) 59:188-97. 2013
    ..Matrix calcification was visualized from Day 6 or Day 9 following irradiation of cells expressing low or high levels of CD146, respectively. ..
  16. doi request reprint The response of human ectomesenchymal dental pulp stem cells to cisplatin treatment
    M Seifrtov√°
    Departments of Medical Biochemistry Histology and Embryology, Faculty of Medicine in Hradec Kralove, Charles University in Prague, Czech Republic
    Int Endod J 45:401-12. 2012
    ..To determine the response of dental pulp stem cells (DPSCs) to DNA-damaging cytostatic cisplatin and compare it with the response of normal human dermal fibroblasts (HDFs)...
  17. ncbi request reprint Stem cell plasticity and issues of stem cell therapy
    S Filip
    Department of Oncology and Radiotherapy, Charles University Hospital, Hradec Kralove, Czech Republic
    Folia Biol (Praha) 51:180-7. 2005
    ..Many experiments are needed before at least some of these questions may be answered and cell therapy become an important method for the benefit of our patients...
  18. ncbi request reprint Role of transplanted bone marrow cells in response to skeletal muscle injury
    D Cizkova
    Department of Histology and Embryology, Faculty of Medicine in Hradec Kralove, Charles University in Prague, Czech Republic
    Folia Biol (Praha) 57:232-41. 2011
    ..Instead, BMCs attempted to resorb necrotic structures, which confirmed the indispensable role of bone marrow-derived macrophages in skeletal muscle regeneration...
  19. ncbi request reprint Activation of mitogen activated protein kinase (MAPK) pathways after soman poisoning in rat cerebellar granule neurons
    J Pejchal
    Center of Advanced Studies, Faculty of Medical Health Sciences, Hradec Kralove, Czech Republic
    J Appl Toxicol 28:689-93. 2008
    ..Delayed activation of p38 MAPK and its targets might be involved in the pathogenetic mechanism of the long-term neurophysiological toxic effects of nerve agents...
  20. ncbi request reprint Adult stem cells and their importance in cell therapy
    S Filip
    Department of Oncology and Radiotherapy, Charles University, Medical Faculty, Hradec Kralove, Czech Republic
    Folia Biol (Praha) 49:9-14. 2003
    ..Much research is to be done and verified in practice and, at the same time, ethical problems must be resolved...
  21. ncbi request reprint Boldine attenuates cholestasis associated with nonalcoholic fatty liver disease in hereditary hypertriglyceridemic rats fed by high-sucrose diet
    M Zagorova
    Department of Pharmacology, Charles University in Prague, Faculty of Medicine in Hradec Kralove, Hradec Kralove, Czech Republic
    Physiol Res 64:S467-76. 2015
    ..Sucrose induced alterations in BF may be alleviated by administration of boldine. ..