Marcela Chmelarová

Summary

Country: Czech Republic

Publications

  1. ncbi request reprint Promoter methylation of GATA4, WIF1, NTRK1 and other selected tumour suppressor genes in ovarian cancer
    M Chmelařová
    Institute for Clinical Biochemistry and Diagnostics, Charles University in Prague Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Czech Republic
    Folia Biol (Praha) 59:87-92. 2013
  2. ncbi request reprint Methylation analysis of tumour suppressor genes in ovarian cancer using MS-MLPA
    M Chmelařová
    Department of Clinical Biochemistry and Diagnostics, Faculty Hospital, Faculty of Medicine Hradec Kralove, Charles University Prague, Hradec Kralove, Czech Republic
    Folia Biol (Praha) 58:246-50. 2012
  3. doi request reprint Methylation in the p53 promoter in epithelial ovarian cancer
    Marcela Chmelarová
    Institute of Clinical Biochemistry and Diagnostics, Medical Faculty of Charles University and Faculty Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic
    Clin Transl Oncol 15:160-3. 2013
  4. ncbi request reprint [The most frequent methods used for DNA methylation analysis]
    Marcela Chmelarová
    Univerzita Karlova v Praze, Lékarská fakulta a FN Hradec Králové, Ustav klinické biochemie a diagnostiky
    Cas Lek Cesk 150:442-5. 2011
  5. doi request reprint Genetic polymorphisms in biotransformation enzymes for benzo[a]pyrene and related levels of benzo[a]pyrene-7,8-diol-9,10-epoxide-DNA adducts in Goeckerman therapy
    Martin Beránek
    Institute of Clinical Biochemistry and Diagnostics, Charles University Hospital and Faculty of Medicine in Hradec Kralove, 50005 Hradec Kralove, Czech Republic Department of Biochemical Sciences, Charles University in Prague, Faculty of Pharmacy in Hradec Kralove, 50005 Hradec Kralove, Czech Republic
    Toxicol Lett 255:47-51. 2016
  6. doi request reprint Importance of promoter methylation of GATA4 gene in epithelial ovarian cancer
    Marcela Chmelarová
    Institute for Clinical Biochemistry and Diagnostics, Faculty of Medicine in Hradec Kralove, Charles University in Prague and University Hospital Hradec Králové, Hradec Kralove, Czech Republic
    Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 157:294-7. 2013

Detail Information

Publications6

  1. ncbi request reprint Promoter methylation of GATA4, WIF1, NTRK1 and other selected tumour suppressor genes in ovarian cancer
    M Chmelařová
    Institute for Clinical Biochemistry and Diagnostics, Charles University in Prague Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Czech Republic
    Folia Biol (Praha) 59:87-92. 2013
    ..These findings could potentially be used in screening of ovarian cancer, and may have implications for future chemotherapy based on epigenetic changes...
  2. ncbi request reprint Methylation analysis of tumour suppressor genes in ovarian cancer using MS-MLPA
    M Chmelařová
    Department of Clinical Biochemistry and Diagnostics, Faculty Hospital, Faculty of Medicine Hradec Kralove, Charles University Prague, Hradec Kralove, Czech Republic
    Folia Biol (Praha) 58:246-50. 2012
    ..These findings could potentially be used in screening of ovarian cancer and may have implications for future chemotherapy based on epigenetic changes...
  3. doi request reprint Methylation in the p53 promoter in epithelial ovarian cancer
    Marcela Chmelarová
    Institute of Clinical Biochemistry and Diagnostics, Medical Faculty of Charles University and Faculty Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic
    Clin Transl Oncol 15:160-3. 2013
    ..The aim of this study was to investigate promoter methylation of p53 gene in ovarian cancer by comparison with normal ovarian tissue...
  4. ncbi request reprint [The most frequent methods used for DNA methylation analysis]
    Marcela Chmelarová
    Univerzita Karlova v Praze, Lékarská fakulta a FN Hradec Králové, Ustav klinické biochemie a diagnostiky
    Cas Lek Cesk 150:442-5. 2011
    ..We reviewed techniques important for monitoring of DNA methylation changes of CpG islands in gene promoter regions. Advantages, disadvantages and potential use of these techniques are described...
  5. doi request reprint Genetic polymorphisms in biotransformation enzymes for benzo[a]pyrene and related levels of benzo[a]pyrene-7,8-diol-9,10-epoxide-DNA adducts in Goeckerman therapy
    Martin Beránek
    Institute of Clinical Biochemistry and Diagnostics, Charles University Hospital and Faculty of Medicine in Hradec Kralove, 50005 Hradec Kralove, Czech Republic Department of Biochemical Sciences, Charles University in Prague, Faculty of Pharmacy in Hradec Kralove, 50005 Hradec Kralove, Czech Republic
    Toxicol Lett 255:47-51. 2016
    ..026). Our data suggest that CYP1B1/EPHX1 genotyping could help to predict the risk of DNA damage and to optimize doses of coal tar and UVR exposure in psoriatic patients in whom GT was applied. ..
  6. doi request reprint Importance of promoter methylation of GATA4 gene in epithelial ovarian cancer
    Marcela Chmelarová
    Institute for Clinical Biochemistry and Diagnostics, Faculty of Medicine in Hradec Kralove, Charles University in Prague and University Hospital Hradec Králové, Hradec Kralove, Czech Republic
    Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 157:294-7. 2013
    ..GATA4 methylation has been reported in a variety of human cancers. The aim of this study was to investigate promoter methylation of the GATA4 gene in ovarian cancer by comparison with that in normal ovarian tissue...