M Eddouks

Summary

Publications

  1. ncbi Ethnopharmacological survey of medicinal plants used for the treatment of diabetes mellitus, hypertension and cardiac diseases in the south-east region of Morocco (Tafilalet)
    M Eddouks
    UFR Physiology of the Nutrition and Endocrinian Pharmacology, Faculty of Sciences and Techniques Errachidia, B P 509, Boutalamine, Errachidia, Morocco
    J Ethnopharmacol 82:97-103. 2002
  2. ncbi Study of the hypoglycaemic activity of Fraxinus excelsior and Silybum marianum in an animal model of type 1 diabetes mellitus
    M Maghrani
    UFR PNPE, BP 21, Errachidia 52000, Morocco
    J Ethnopharmacol 91:309-16. 2004
  3. ncbi Fraxinus excelsior L. evokes a hypotensive action in normal and spontaneously hypertensive rats
    M Eddouks
    UFR PNPE P B 21, Boutalamine, Errachidia 52000, Morocco
    J Ethnopharmacol 99:49-54. 2005
  4. doi Cardiovascular effect of Artemisia herba alba aqueous extract in spontaneously hypertensive rats
    N A Zeggwagh
    Moulay Ismail University, Errachidia, Morocco
    Methods Find Exp Clin Pharmacol 30:375-81. 2008
  5. ncbi Effect of the desert plant Retama raetam on glycaemia in normal and streptozotocin-induced diabetic rats
    Mhamed Maghrani
    UFR Physiology of the Nutrition and Endocrinian Pharmacology, Faculty of Sciences and Techniques Errachidia, Boutalamine, B P 509, Errachidia, Morocco
    J Ethnopharmacol 87:21-5. 2003
  6. ncbi Caraway and caper: potential anti-hyperglycaemic plants in diabetic rats
    M Eddouks
    Laboratory of Endocrinian Physiology, FSTE Boutalamine and Pharmacology, EDDOUKS, UFR PNPE, BP 21, Errachidia 52000, Morocco
    J Ethnopharmacol 94:143-8. 2004
  7. ncbi Hypolipidemic activity of aqueous extract of Capparis spinosa L. in normal and diabetic rats
    M Eddouks
    UFR PNPE, B P 21, Boutalamine, Errachidia 52000, Morocco
    J Ethnopharmacol 98:345-50. 2005
  8. ncbi Potent hypoglycaemic activity of the aqueous extract of Chamaemelum nobile in normal and streptozotocin-induced diabetic rats
    M Eddouks
    UFR PNPE, BP 21, Errachidia, Morocco 52000
    Diabetes Res Clin Pract 67:189-95. 2005
  9. ncbi Study of the hypoglycaemic activity of Lepidium sativum L. aqueous extract in normal and diabetic rats
    M Eddouks
    UFR PNPE P B 21, Errachidia 52000, Morocco
    J Ethnopharmacol 97:391-5. 2005
  10. ncbi Phlorizin-like effect of Fraxinus excelsior in normal and diabetic rats
    M Eddouks
    UFR Physiology of the Nutrition and PNPE, BP 21, Boutalamine, Errachidia, Morocco
    J Ethnopharmacol 94:149-54. 2004

Collaborators

  • M A Lacaille-Dubois
  • R Burcelin
  • N A Zeggwagh
  • A Lemhadri
  • M Maghrani
  • H Jouad
  • J B Michel
  • M Haloui
  • M Hebi
  • M El Amraoui
  • Mhamed Maghrani
  • M Ajebli
  • M Benwahhoud
  • B Lyoussi
  • O Farid
  • L Hajji
  • M L Ouahidi
  • A El Amraoui
  • Hassan Jouad
  • Ahmed Lemhadri
  • Jean Baptiste Michel
  • H Rhiouani
  • J El Hilaly

Detail Information

Publications25

  1. ncbi Ethnopharmacological survey of medicinal plants used for the treatment of diabetes mellitus, hypertension and cardiac diseases in the south-east region of Morocco (Tafilalet)
    M Eddouks
    UFR Physiology of the Nutrition and Endocrinian Pharmacology, Faculty of Sciences and Techniques Errachidia, B P 509, Boutalamine, Errachidia, Morocco
    J Ethnopharmacol 82:97-103. 2002
    ..Some toxic plants have also been reported. In conclusion Tafilalet region disposes of a large phytotherapy knowledge which must be scientifically investigated especially in treating diabetes mellitus, hypertension and cardiac diseases...
  2. ncbi Study of the hypoglycaemic activity of Fraxinus excelsior and Silybum marianum in an animal model of type 1 diabetes mellitus
    M Maghrani
    UFR PNPE, BP 21, Errachidia 52000, Morocco
    J Ethnopharmacol 91:309-16. 2004
    ..We conclude that the aqueous extracts of FE and SM exhibit potent hypoglycaemic and anti-hyperglycaemic activities in normal and STZ rats, respectively, without affecting basal plasma insulin concentrations...
  3. ncbi Fraxinus excelsior L. evokes a hypotensive action in normal and spontaneously hypertensive rats
    M Eddouks
    UFR PNPE P B 21, Boutalamine, Errachidia 52000, Morocco
    J Ethnopharmacol 99:49-54. 2005
    ..001) after Fraxinus excelsior treatment. These results suggest that oral administration of aqueous extract of Fraxinus excelsior exhibited hypotensive and diuretic actions...
  4. doi Cardiovascular effect of Artemisia herba alba aqueous extract in spontaneously hypertensive rats
    N A Zeggwagh
    Moulay Ismail University, Errachidia, Morocco
    Methods Find Exp Clin Pharmacol 30:375-81. 2008
    ..05) after 20 days of oral administration. We conclude that AHAE possesses antihypertensive activity in SHR and that the underlying mechanism appears to involve, at least in part, an increase in urine and electrolyte output...
  5. ncbi Effect of the desert plant Retama raetam on glycaemia in normal and streptozotocin-induced diabetic rats
    Mhamed Maghrani
    UFR Physiology of the Nutrition and Endocrinian Pharmacology, Faculty of Sciences and Techniques Errachidia, Boutalamine, B P 509, Errachidia, Morocco
    J Ethnopharmacol 87:21-5. 2003
    ..These findings suggest that the aqueous extract of RR possess significant hypoglycaemic effect in both normal and STZ diabetic rats...
  6. ncbi Caraway and caper: potential anti-hyperglycaemic plants in diabetic rats
    M Eddouks
    Laboratory of Endocrinian Physiology, FSTE Boutalamine and Pharmacology, EDDOUKS, UFR PNPE, BP 21, Errachidia 52000, Morocco
    J Ethnopharmacol 94:143-8. 2004
    ..We conclude that aqueous extracts of CC and CS exhibit a potent anti-hyperglycaemic activity in STZ rats without affecting basal plasma insulin concentrations...
  7. ncbi Hypolipidemic activity of aqueous extract of Capparis spinosa L. in normal and diabetic rats
    M Eddouks
    UFR PNPE, B P 21, Boutalamine, Errachidia 52000, Morocco
    J Ethnopharmacol 98:345-50. 2005
    ..05). We conclude that the aqueous extract of CS (20 mg/kg) exhibits a potent lipid lowering activity in both normal and severe hyperglycemic rats after repeated oral administration of CS aqueous extract...
  8. ncbi Potent hypoglycaemic activity of the aqueous extract of Chamaemelum nobile in normal and streptozotocin-induced diabetic rats
    M Eddouks
    UFR PNPE, BP 21, Errachidia, Morocco 52000
    Diabetes Res Clin Pract 67:189-95. 2005
    ..nobile exhibits a significant hypoglycaemic effect in normal and STZ diabetic rats without affecting basal plasma insulin concentrations and support, therefore, its traditional use by the Moroccan population...
  9. ncbi Study of the hypoglycaemic activity of Lepidium sativum L. aqueous extract in normal and diabetic rats
    M Eddouks
    UFR PNPE P B 21, Errachidia 52000, Morocco
    J Ethnopharmacol 97:391-5. 2005
    ..We conclude that the aqueous extract of LS exhibits a potent hypoglycaemic activity in rats without affecting basal plasma insulin concentrations...
  10. ncbi Phlorizin-like effect of Fraxinus excelsior in normal and diabetic rats
    M Eddouks
    UFR Physiology of the Nutrition and PNPE, BP 21, Boutalamine, Errachidia, Morocco
    J Ethnopharmacol 94:149-54. 2004
    ..This renal effect might be at least one mechanism explaining the observed hypoglycaemic activity of this plant in normal and diabetic rats...
  11. ncbi Hypoglycaemic effect of Triticum repens P. Beauv. in normal and diabetic rats
    M Eddouks
    UFR PNPE, BP 21, Errachidia 52000, Morocco
    J Ethnopharmacol 102:228-32. 2005
    ..We conclude that the aqueous extract of TR exhibits a potent hypoglycaemic activity in STZ rats without affecting basal plasma insulin concentrations...
  12. ncbi Inhibition of endogenous glucose production accounts for hypoglycemic effect of Spergularia purpurea in streptozotocin mice
    M Eddouks
    UFR Physiology of the Nutrition and Endocrinian Pharmacology, Faculty of Sciences and Techniques Errachidia, Boutalamine, Errachidia, Morocco
    Phytomedicine 10:594-9. 2003
    ..001). We conclude that aqueous extract perfusion of SP inhibits endogenous glucose production in mice. This inhibition is at least one mechanism explaining the observed hypoglycemic activity of this plant in diabetic animals...
  13. ncbi Antihypertensive activity of the aqueous extract of Retama raetam Forssk. leaves in spontaneously hypertensive rats
    M Eddouks
    Faculty of Sciences and Techniques, BP 21, Errachidia, 52000, Morocco
    J Herb Pharmacother 7:65-77. 2007
    ..01) and a no significant increase in SHR rats. These results suggest that oral administration of aqueous RR extract exhibited antihypertensive and diuretic effects in SHR rats and diuretic action in WKY rats...
  14. ncbi Study of hypoglycaemic and hypolipidemic effects of Inula viscosa L. aqueous extract in normal and diabetic rats
    N A Zeggwagh
    PNPE, BP 21, Errachidia 52000, Morocco
    J Ethnopharmacol 108:223-7. 2006
    ..We conclude that Inula viscosa possess a hypoglycaemic but not hypolipidemic activity in normal and diabetic rats. The observed hypoglycaemic activity seems to be independent of insulin secretion...
  15. ncbi Hypoglycaemic effect of Calamintha officinalis Moench. in normal and streptozotocin-induced diabetic rats
    A Lemhadri
    UFR PNPE BP 21, Errachidia, 52000, Morocco
    J Pharm Pharmacol 56:795-9. 2004
    ..officinalis extract exhibits a significant hypoglycaemic effect in normal and STZ diabetic rats without affecting basal plasma insulin concentrations, and supports, therefore, its traditional use by the Moroccan population...
  16. ncbi Cholesterol and triglycerides lowering activities of caraway fruits in normal and streptozotocin diabetic rats
    A Lemhadri
    UFR PNPE B P 21, Errachidia 52000, Morocco
    J Ethnopharmacol 106:321-6. 2006
    ..We conclude that the aqueous extract of Carum carvi (20mg/kg) exhibits a potent lipid lowering activity in both normal and severe hyperglycemic rats after repeated oral administration of Carum carvi aqueous extract...
  17. ncbi Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region
    A Lemhadri
    Laboratory of Endocrinian Physiology, F S T E Boutalamine and Pharmacology, UFR PNPE, BP 21, Errachidia 52000, Morocco
    J Ethnopharmacol 92:251-6. 2004
    ..We conclude that an aqueous extract of OV exhibits an anti-hyperglycaemic activity in STZ rats without affecting basal plasma insulin concentrations...
  18. ncbi Effects of an aqueous extract of Triticum repens on lipid metabolism in normal and recent-onset diabetic rats
    M Maghrani
    UFR PNPE, BP 21, Errachidia, Morocco
    J Ethnopharmacol 90:331-7. 2004
    ..05). We conclude that the aqueous extract of TR exhibits lipid and body weight lowering activities in severe hyperglycaemic rats after repeated oral administration of aqueous TR extract at a dose of 20 mg/kg...
  19. ncbi Effects of the flavonoids extracted from Spergularia purpurea Pers. on arterial blood pressure and renal function in normal and hypertensive rats
    H Jouad
    Laboratory of Endocrinian Physiology and Pharmacology. F.S.T.B. Boutalamine, B.P. 509, Errachidia, Morocco
    J Ethnopharmacol 76:159-63. 2001
    ..05). These results suggest that oral administration of flavonoids obtained from Spergularia purpurea exhibited antihypertensive and diuretic actions...
  20. ncbi Effect of Retama raetam on lipid metabolism in normal and recent-onset diabetic rats
    M Maghrani
    UFR Physiology of the Nutrition and Endocrinian Pharmacology, BP 688, Boutalamine, Errachidia, Morocco
    J Ethnopharmacol 90:323-9. 2004
    ..05). We conclude that the aqueous extract of RR exhibits lipid and body weight lowering activities in both normal and severe hyperglycemic rats after repeated oral administration of RR aqueous extract at a dose of 20 mg/kg...
  21. ncbi Chronic diuretic effect of the water extract of Spergularia purpurea in normal rats
    H Jouad
    Laboratory of Endocrinian Physiology and Pharmacology, F.S.T.E. Boutalamine, B.P. 509, Errachidia, Morocco
    J Ethnopharmacol 75:219-23. 2001
    ..05) for both doses of water extract (100 and 400 mg/kg). It is concluded that the water extract of whole plant of SP has a significant diuretic effect in rats...
  22. ncbi Acute diuretic effect of aqueous extract of Retama raetam in normal rats
    M Maghrani
    UFR PNPE, BP 21, Errachidia, Morocco
    J Ethnopharmacol 99:31-5. 2005
    ..001). However, RR extract did not affect plasma urea levels, urine pH, plasma osmolarity and hematocrite. It is then concluded that the water extract of the aerial parts of RR exhibited a significant diuretic effect in normal rat...
  23. ncbi Ethnobotanical survey of medicinal plants used for the treatment of diabetes, cardiac and renal diseases in the North centre region of Morocco (Fez-Boulemane)
    H Jouad
    Laboratory of Endocrinian Physiology and Pharmacology, F.S.T.E. Boutalamine, BP 509, Errachidia, Morocco
    J Ethnopharmacol 77:175-82. 2001
    ..The result indicated that nine plants are extremely toxic at high doses and chronic treatment. Fifty nine percent of the interviewers have indicated that they used medicinal plants from the experience of the other...
  24. ncbi Pharmacological evidence of α-adrenergic receptors in the hypotensive effect of Chamaemulum nobile L
    M Hebi
    Faculty of Sciences and Techniques Errachidia, Moulay Ismail University, BP 509, Boutalamine, 52000, Morocco, BP 21, Errachidia, 52000, Morocco
    Cardiovasc Hematol Agents Med Chem . 2016
    ..We conclude that aqueous Cn extract exhibits a hypotensive effect which may be probably due to an alpha adrenergic receptor blockade mechanism...
  25. ncbi Hypoglycemic effect of Suaeda fruticosa in streptozotocin-induced diabetic rats
    M Benwahhoud
    UFR Physiology-Pharmacology. Laboratory of Animal Physiology. Faculty of Science Dhar-Mahraz. B.P. 1796 Atlas, Fez, Morocco
    J Ethnopharmacol 76:35-8. 2001
    ..In order to characterize the active principle(s), which could be responsible for the therapeutic effect, preliminary phytochemical analysis of the aqueous extract of the plant has been investigated...