Omotayo Erejuwa

Summary

Publications

  1. doi request reprint Antioxidant protection of Malaysian tualang honey in pancreas of normal and streptozotocin-induced diabetic rats
    O O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
    Ann Endocrinol (Paris) 71:291-6. 2010
  2. doi request reprint Hypoglycemic and antioxidant effects of honey supplementation in streptozotocin-induced diabetic rats
    O O Erejuwa
    Department of Pharmacology, School of Medical Sciences, University Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
    Int J Vitam Nutr Res 80:74-82. 2010
  3. pmc Antioxidant protective effect of glibenclamide and metformin in combination with honey in pancreas of streptozotocin-induced diabetic rats
    Omotayo Owomofoyon Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia E Mails S A S M S A W
    Int J Mol Sci 11:2056-66. 2010
  4. pmc Comparison of antioxidant effects of honey, glibenclamide, metformin, and their combinations in the kidneys of streptozotocin-induced diabetic rats
    Omotayo Owomofoyon Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia E Mails S A S M S A W
    Int J Mol Sci 12:829-43. 2011
  5. pmc Glibenclamide or metformin combined with honey improves glycemic control in streptozotocin-induced diabetic rats
    Omotayo Owomofoyon Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia
    Int J Biol Sci 7:244-52. 2011
  6. pmc Differential responses to blood pressure and oxidative stress in streptozotocin-induced diabetic Wistar-Kyoto rats and spontaneously hypertensive rats: effects of antioxidant (honey) treatment
    Omotayo O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia E Mails S A S M S A W
    Int J Mol Sci 12:1888-907. 2011
  7. pmc Nigerian Honey Ameliorates Hyperglycemia and Dyslipidemia in Alloxan-Induced Diabetic Rats
    Omotayo O Erejuwa
    Department of Pharmacology and Therapeutics, Faculty of Medicine, Ebonyi State University, Abakaliki 480214, Ebonyi State, Nigeria
    Nutrients 8:95. 2016
  8. pmc Evidence in support of potential applications of lipid peroxidation products in cancer treatment
    Omotayo O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
    Oxid Med Cell Longev 2013:931251. 2013
  9. pmc Modulation of gut microbiota in the management of metabolic disorders: the prospects and challenges
    Omotayo O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
    Int J Mol Sci 15:4158-88. 2014
  10. doi request reprint Effects of honey and its mechanisms of action on the development and progression of cancer
    Omotayo O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
    Molecules 19:2497-522. 2014

Collaborators

Detail Information

Publications16

  1. doi request reprint Antioxidant protection of Malaysian tualang honey in pancreas of normal and streptozotocin-induced diabetic rats
    O O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
    Ann Endocrinol (Paris) 71:291-6. 2010
    ..05) reduced elevated MDA levels. Honey treatment also restored SOD and CAT activities. These results suggest that hypoglycemic effect of tualang honey might be attributed to its antioxidative effect on the pancreas...
  2. doi request reprint Hypoglycemic and antioxidant effects of honey supplementation in streptozotocin-induced diabetic rats
    O O Erejuwa
    Department of Pharmacology, School of Medical Sciences, University Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
    Int J Vitam Nutr Res 80:74-82. 2010
    ..The aims of this study were to investigate whether honey could reduce hyperglycemia and ameliorate oxidative stress in kidneys of streptozotocin-induced diabetic rats...
  3. pmc Antioxidant protective effect of glibenclamide and metformin in combination with honey in pancreas of streptozotocin-induced diabetic rats
    Omotayo Owomofoyon Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia E Mails S A S M S A W
    Int J Mol Sci 11:2056-66. 2010
    ..These findings suggest that tualang honey potentiates the effect of glibenclamide and metformin to protect diabetic rat pancreas against oxidative stress and damage...
  4. pmc Comparison of antioxidant effects of honey, glibenclamide, metformin, and their combinations in the kidneys of streptozotocin-induced diabetic rats
    Omotayo Owomofoyon Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia E Mails S A S M S A W
    Int J Mol Sci 12:829-43. 2011
    ..These results suggest that combination of honey with metformin or glibenclamide might offer additional antioxidant effect to these drugs. This might reduce oxidative stress-mediated damage in diabetic kidneys...
  5. pmc Glibenclamide or metformin combined with honey improves glycemic control in streptozotocin-induced diabetic rats
    Omotayo Owomofoyon Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia
    Int J Biol Sci 7:244-52. 2011
    ..These results indicate that combination of glibenclamide or metformin with honey improves glycemic control, and provides additional metabolic benefits, not achieved with either glibenclamide or metformin alone...
  6. pmc Differential responses to blood pressure and oxidative stress in streptozotocin-induced diabetic Wistar-Kyoto rats and spontaneously hypertensive rats: effects of antioxidant (honey) treatment
    Omotayo O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia E Mails S A S M S A W
    Int J Mol Sci 12:1888-907. 2011
    ..These data suggest that differences in types, severity, and complications of diseases as well as strains may influence responses to blood pressure and oxidative stress...
  7. pmc Nigerian Honey Ameliorates Hyperglycemia and Dyslipidemia in Alloxan-Induced Diabetic Rats
    Omotayo O Erejuwa
    Department of Pharmacology and Therapeutics, Faculty of Medicine, Ebonyi State University, Abakaliki 480214, Ebonyi State, Nigeria
    Nutrients 8:95. 2016
    ..05) reduced TGs and VLDL cholesterol. This study confirms the reproducibility of glucose lowering and hypolipidemic effects of honey using Nigerian honey. However, none of the doses deteriorated hyperglycemia and dyslipidemia. ..
  8. pmc Evidence in support of potential applications of lipid peroxidation products in cancer treatment
    Omotayo O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
    Oxid Med Cell Longev 2013:931251. 2013
    ..This may prove to be an important strategy to complement current treatment regimens for cancer patients. ..
  9. pmc Modulation of gut microbiota in the management of metabolic disorders: the prospects and challenges
    Omotayo O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
    Int J Mol Sci 15:4158-88. 2014
    ..However, considering that research investigating the role of gut microbiota in metabolic diseases is still in its infancy, more rigorous and well-designed in vitro, animal and clinical studies are needed. ..
  10. doi request reprint Effects of honey and its mechanisms of action on the development and progression of cancer
    Omotayo O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
    Molecules 19:2497-522. 2014
    ..Thus, it may serve as a potential and promising anticancer agent which warrants further experimental and clinical studies. ..
  11. pmc Honey--a novel antidiabetic agent
    Omotayo O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia
    Int J Biol Sci 8:913-34. 2012
    ..Hence, it is very important to have well-designed, randomized controlled clinical trials that investigate the reproducibility (or otherwise) of these experimental data in diabetic human subjects...
  12. doi request reprint Honey: a novel antioxidant
    Omotayo O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
    Molecules 17:4400-23. 2012
    ..In view of the fact that the majority of these data emanate from animal studies, there is an urgent need to investigate this antioxidant effect of honey in human subjects with chronic or degenerative diseases...
  13. pmc Management of diabetes mellitus: could simultaneous targeting of hyperglycemia and oxidative stress be a better panacea?
    Omotayo O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia E Mail Tel 60 9766 6877
    Int J Mol Sci 13:2965-72. 2012
    ....
  14. pmc Honey supplementation in spontaneously hypertensive rats elicits antihypertensive effect via amelioration of renal oxidative stress
    Omotayo O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, 16150 Kubang Kerian, Malaysia
    Oxid Med Cell Longev 2012:374037. 2012
    ..These results indicate that Nrf2 expression is impaired in the kidney of SHR. Honey supplementation considerably reduces elevated SBP via amelioration of oxidative stress in the kidney of SHR...
  15. doi request reprint Fructose might contribute to the hypoglycemic effect of honey
    Omotayo O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
    Molecules 17:1900-15. 2012
    ..In view of the similarities of these effects of fructose with those of honey, the evidence may support the role of fructose in honey in mediating the hypoglycemic effect of honey...
  16. doi request reprint Oligosaccharides might contribute to the antidiabetic effect of honey: a review of the literature
    Omotayo O Erejuwa
    Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
    Molecules 17:248-66. 2011
    ..We anticipate that the possibility of oligosaccharides in honey contributing to the antidiabetic and other health-related effects of honey will stimulate a renewed research interest in this field...