Stefan Monecke

Summary

Affiliation: Faculty of Medicine

Publications

  1. pmc A clonal complex 12 methicillin-resistant Staphylococcus aureus strain, West Australian MRSA-59, harbors a novel pseudo-SCCmec element
    Stefan Monecke
    Alere Technologies GmbH, Jena, Germany Institute for Medical Microbiology and Hygiene, Faculty of Medicine Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany InfectoGnostics, Forschungscampus, Jena, Germany
    Antimicrob Agents Chemother 59:7142-4. 2015
  2. doi request reprint Influence of polymerase brand on microarray-based spoligotyping in low concentrations of mycobacterial DNA
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Technische Universitat Dresden, Dresden, Germany Alere Technologies GmbH, Jena, Germany InfectoGnostics Research Campus Jena, Jena, Germany Electronic address
    Mol Cell Probes 29:126-8. 2015
  3. pmc Genome sequencing and molecular characterisation of Staphylococcus aureus ST772-MRSA-V, "Bengal Bay Clone"
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany
    BMC Res Notes 6:548. 2013
  4. pmc Detection of mecC-positive Staphylococcus aureus (CC130-MRSA-XI) in diseased European hedgehogs (Erinaceus europaeus) in Sweden
    Stefan Monecke
    Alere Technologies GmbH, Jena, Germany
    PLoS ONE 8:e66166. 2013
  5. pmc Rapid microarray-based identification of different mecA alleles in Staphylococci
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany
    Antimicrob Agents Chemother 56:5547-54. 2012
  6. pmc Rapid detection of Panton-Valentine leukocidin in Staphylococcus aureus cultures by use of a lateral flow assay based on monoclonal antibodies
    Stefan Monecke
    Alere Technologies GmbH, Jena, Germany
    J Clin Microbiol 51:487-95. 2013
  7. doi request reprint Genotyping of Staphylococcus aureus isolates from diseased poultry
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany
    Vet Microbiol 162:806-12. 2013
  8. pmc Characterisation of MRSA strains isolated from patients in a hospital in Riyadh, Kingdom of Saudi Arabia
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany
    BMC Microbiol 12:146. 2012
  9. doi request reprint Molecular epidemiology and characterisation of MRSA isolates from Trinidad and Tobago
    S Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany
    Eur J Clin Microbiol Infect Dis 31:1497-500. 2012
  10. doi request reprint Distribution of SCCmec-associated phenol-soluble modulin in staphylococci
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany
    Mol Cell Probes 26:99-103. 2012

Collaborators

Detail Information

Publications50

  1. pmc A clonal complex 12 methicillin-resistant Staphylococcus aureus strain, West Australian MRSA-59, harbors a novel pseudo-SCCmec element
    Stefan Monecke
    Alere Technologies GmbH, Jena, Germany Institute for Medical Microbiology and Hygiene, Faculty of Medicine Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany InfectoGnostics, Forschungscampus, Jena, Germany
    Antimicrob Agents Chemother 59:7142-4. 2015
    ..One harbors PSM-mec and xylR (mecR2). It is found in SCCmec types II, III, and VIII. The second subtype, described herein, is present in WA MRSA-59 and some coagulase-negative staphylococci. ..
  2. doi request reprint Influence of polymerase brand on microarray-based spoligotyping in low concentrations of mycobacterial DNA
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Technische Universitat Dresden, Dresden, Germany Alere Technologies GmbH, Jena, Germany InfectoGnostics Research Campus Jena, Jena, Germany Electronic address
    Mol Cell Probes 29:126-8. 2015
    ..Direct spoligotyping from samples with very low concentrations of mycobacterial DNA thus requires careful selection of polymerase and strict standardization. ..
  3. pmc Genome sequencing and molecular characterisation of Staphylococcus aureus ST772-MRSA-V, "Bengal Bay Clone"
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany
    BMC Res Notes 6:548. 2013
    ..It is found increasingly common in other areas of the world...
  4. pmc Detection of mecC-positive Staphylococcus aureus (CC130-MRSA-XI) in diseased European hedgehogs (Erinaceus europaeus) in Sweden
    Stefan Monecke
    Alere Technologies GmbH, Jena, Germany
    PLoS ONE 8:e66166. 2013
    ..This and several other recent observations suggest that CC130 might be a zoonotic lineage of S. aureus and that SCCmec XI/mecC may have originated from animal pathogens...
  5. pmc Rapid microarray-based identification of different mecA alleles in Staphylococci
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany
    Antimicrob Agents Chemother 56:5547-54. 2012
    ..vitulinus. Because of the diversity of sequences and the different impact on β-lactam susceptibility, the existence of different mecA alleles needs to be taken into account when designing diagnostic assays for the detection of mecA...
  6. pmc Rapid detection of Panton-Valentine leukocidin in Staphylococcus aureus cultures by use of a lateral flow assay based on monoclonal antibodies
    Stefan Monecke
    Alere Technologies GmbH, Jena, Germany
    J Clin Microbiol 51:487-95. 2013
    ..As the test utilizes cultures from standard media and does not require sophisticated equipment, it can be easily integrated into a laboratory's workflow and might contribute to timely therapy of PVL-associated infections...
  7. doi request reprint Genotyping of Staphylococcus aureus isolates from diseased poultry
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany
    Vet Microbiol 162:806-12. 2013
    ..8%), all belonging to CC398-MRSA-V. These data show that the current dissemination of livestock-associated MRSA also engulfs chickens and turkeys, and that MRSA surveillance among these species is warranted...
  8. pmc Characterisation of MRSA strains isolated from patients in a hospital in Riyadh, Kingdom of Saudi Arabia
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany
    BMC Microbiol 12:146. 2012
    ..In order to obtain data on the population structure of MRSA in Riyadh, Saudi Arabia, 107 clinical and environmental MRSA isolates were genotyped using a microarray-based assay...
  9. doi request reprint Molecular epidemiology and characterisation of MRSA isolates from Trinidad and Tobago
    S Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany
    Eur J Clin Microbiol Infect Dis 31:1497-500. 2012
    ..Thus, infection control procedures within medical facilities need to be revised and enforced. This could substantially reduce the burden of MRSA to healthcare in Trinidad and Tobago...
  10. doi request reprint Distribution of SCCmec-associated phenol-soluble modulin in staphylococci
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany
    Mol Cell Probes 26:99-103. 2012
    ..It was identified in isolates harbouring SCCmec types II, IIA, IIB, IID, III, VIII and in some irregular or truncated elements...
  11. pmc Methicillin sensitive Staphylococcus aureus producing Panton-Valentine leukocidin toxin in Trinidad & Tobago: a case report
    Patrick E Akpaka
    Microbiology Pathology Unit, Department of Para Clinical Sciences, Faculty of Medical Sciences, University of the West Indies, St Augustine, Trinidad
    J Med Case Rep 5:157. 2011
    ..To the best of our knowledge, this is the first time that such a case has been identified and reported from this country...
  12. pmc Evolution and diversity of community-associated methicillin-resistant Staphylococcus aureus in a geographical region
    Geoffrey W Coombs
    Australian Collaborating Centre for Enterococcus and Staphylococcus Species Typing and Research, PathWest Laboratory Medicine WA, Royal Perth Hospital, Wellington Street, Perth, Western Australia, 6000 Australia
    BMC Microbiol 11:215. 2011
    ..aureus SCCmec acquisition within a region...
  13. ncbi request reprint Microarray based study on virulence-associated genes and resistance determinants of Staphylococcus aureus isolates from cattle
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Faculty of Medicine, Carl Gustav Carus at the Technical University of Dresden, Fetscherstrasse 74, D 01307, Dresden, Germany
    Vet Microbiol 125:128-40. 2007
    ..The presence of these two strains highlights the possibility of transfers of S. aureus strains between different host species...
  14. pmc Presence of enterohemorrhagic Escherichia coli ST678/O104:H4 in France prior to 2011
    Stefan Monecke
    Alere Technologies GmbH, Jena, Germany
    Appl Environ Microbiol 77:8784-6. 2011
    ..Both were characterized and compared to the strain which caused the German outbreak in 2011 and to other O104:H4 strains. This suggests that different O104:H4 EHEC strains were present several years prior to the 2011 outbreak...
  15. pmc A field guide to pandemic, epidemic and sporadic clones of methicillin-resistant Staphylococcus aureus
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany
    PLoS ONE 6:e17936. 2011
    ..The data also indicate a high rate of genetic recombination in MRSA involving SCC elements, bacteriophages or other mobile genetic elements and large-scale chromosomal replacements...
  16. doi request reprint Microarray-based genotyping of Staphylococcus aureus isolates from camels
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Faculty of Medicine Carl Gustav Carus, Technical University of Dresden, Fetscherstrasse 74, D 01307 Dresden, Germany
    Vet Microbiol 150:309-14. 2011
    ..This study provides first genotyping data on the population structure and the presence of toxin genes and resistance markers of S. aureus strains in Middle Eastern camels...
  17. pmc Characterisation of Australian MRSA strains ST75- and ST883-MRSA-IV and analysis of their accessory gene regulator locus
    Stefan Monecke
    Faculty of Medicine Carl Gustav Carus, Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany
    PLoS ONE 5:e14025. 2010
    ..Some of these strains, belonging to sequence types ST75 and ST883, have previously been reported to harbour highly divergent alleles of the housekeeping genes used in multilocus sequence typing...
  18. ncbi request reprint Microarray-based characterisation of a Panton-Valentine leukocidin-positive community-acquired strain of methicillin-resistant Staphylococcus aureus
    S Monecke
    Institute for Medical Microbiology and Hygiene, Faculty of Medicine, Carl Gustav Carus at the Technical University of Dresden, Dresden, Germany
    Clin Microbiol Infect 12:718-28. 2006
    ..Comparative analysis of other isolates from Australia, Germany, Switzerland and the UK showed that these isolates were representative of a widespread clone of caMRSA...
  19. ncbi request reprint High diversity of Panton-Valentine leukocidin-positive, methicillin-susceptible isolates of Staphylococcus aureus and implications for the evolution of community-associated methicillin-resistant S. aureus
    S Monecke
    Institute for Medical Microbiology and Hygiene, Faculty of Medicine Carl Gustav Carus, Technical University of Dresden, Dresden, Germany
    Clin Microbiol Infect 13:1157-64. 2007
    ..These findings indicate that the current rise in PVL-positive CaMRSA could be caused by the dissemination of novel SCCmec elements among pre-existing PVL-positive strains, rather than by the spread of PVL phages among MRSA strains...
  20. doi request reprint DNA microarray-based genotyping of methicillin-resistant Staphylococcus aureus strains from Eastern Saxony
    S Monecke
    Institute for Medical Microbiology and Hygiene, Faculty of Medicine Carl Gustav Carus, Technical University of Dresden, Dresden, Germany
    Clin Microbiol Infect 14:534-45. 2008
    ..Detection of such variants can sometimes allow epidemic strains to be resolved beyond spa types to a hospital-specific level, which is of significant value for epidemiological purposes...
  21. ncbi request reprint Rapid genotyping of methicillin-resistant Staphylococcus aureus (MRSA) isolates using miniaturised oligonucleotide arrays
    S Monecke
    Institute for Medical Microbiology and Hygiene, Faculty of Medicine Carl Gustav Carus, Technical University of Dresden, Dresden, Germany
    Clin Microbiol Infect 11:825-33. 2005
    ..The DNA array facilitated rapid and reliable detection of resistance determinants and toxins under conditions used in a routine laboratory and has the potential to be used for array-based high-throughput screening...
  22. doi request reprint Assignment of Staphylococcus aureus isolates to clonal complexes based on microarray analysis and pattern recognition
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Faculty of Medicine Carl Gustav Carus, Technical University of Dresden, Dresden, Germany
    FEMS Immunol Med Microbiol 53:237-51. 2008
    ..Additionally, there are some isolated lineages, such as ST75, ST93, or ST152. These strains produce aberrant hybridization profiles, indicating that only a part of the gene pool of S. aureus has been investigated yet...
  23. ncbi request reprint Phase variation of the multiple banded protein in Ureaplasma urealyticum and Ureaplasma parvum
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Medical Faculty, Technical University of Dresden, Germany
    Int J Med Microbiol 293:203-11. 2003
    ..Therefore, it is proposed that the multiple banded proteins of U. urealyticum and U. parvum are subjected to a phase-switching mechanism as it has already been described for several other Mycoplasmatales...
  24. doi request reprint Molecular epidemiology of Staphylococcus aureus in asymptomatic carriers
    S Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Fetscherstrasse 74, Dresden 01307, Germany
    Eur J Clin Microbiol Infect Dis 28:1159-65. 2009
    ..These data provide an insight into its pathogenesis, especially when compared to isolates from patients with defined clinical conditions. They might also be helpful for the design of a future vaccine...
  25. doi request reprint The molecular epidemiology and evolution of the Panton-Valentine leukocidin-positive, methicillin-resistant Staphylococcus aureus strain USA300 in Western Australia
    S Monecke
    Institute for Medical Microbiology and Hygiene, Faculty of Medicine Carl Gustav Carus, Technical University of Dresden, D 01307 Dresden, Germany
    Clin Microbiol Infect 15:770-6. 2009
    ..The present study emphasises the importance of genotyping in detecting the introduction and evolution of significant MRSA strains within a community...
  26. doi request reprint Modelling the black death. A historical case study and implications for the epidemiology of bubonic plague
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Faculty of Medicine Carl Gustav Carus, Technical University of Dresden, Fetscherstrasse 74, D 01307 Dresden, Germany
    Int J Med Microbiol 299:582-93. 2009
    ....
  27. doi request reprint Intra-strain variability of methicillin-resistant Staphylococcus aureus strains ST228-MRSA-I and ST5-MRSA-II
    S Monecke
    Institute for Medical Microbiology and Hygiene, Faculty of Medicine Carl Gustav Carus, Technical University of Dresden, Fetscherstrasse 74, 01307, Dresden, Germany
    Eur J Clin Microbiol Infect Dis 28:1383-90. 2009
    ..The use of this variability for typing purposes as well as its phylogenetic significance are discussed...
  28. ncbi request reprint Comparative genomics and DNA array-based genotyping of pandemic Staphylococcus aureus strains encoding Panton-Valentine leukocidin
    S Monecke
    Institute for Medical Microbiology and Hygiene, Faculty of Medicine Carl Gustav Carus, Technical University of Dresden, Dresden, Germany
    Clin Microbiol Infect 13:236-49. 2007
    ..The DNA microarray technique provides a valuable epidemiological tool for the detailed characterisation of clinical isolates and comparison of strains at a global level...
  29. pmc Leukocidin genes lukF-P83 and lukM are associated with Taphylococcus aureus clonal complexes 151, 479 and 133 isolated from bovine udder infections in Thuringia, Germany
    Katharina Schlotter
    Thüringer Tierseuchenkasse Livestock Health Service and Insurance Agency of the State of Thuringia, Victor Goerttler Straße 4, 07745, Jena, Germany
    Vet Res 43:42. 2012
    ..The consistent occurrence of lukF-P83/lukM in the dominating clonal complexes suggests an essential role of this leukocidin in the etiology of bovine mastitis...
  30. doi request reprint Disseminated cutaneous and pulmonary abscesses in an injecting drug user caused by a Panton-Valentine leucocidin-positive, methicillin-susceptible Staphylococcus aureus strain
    A Ditzen
    Department of Medicine III, University Hospital of Dresden, Fetscherstrasse 74, 01307, Dresden, Germany
    Eur J Clin Microbiol Infect Dis 27:1013-5. 2008
    ..The use of diagnostic microarrays contributes to patient care by the simultaneous detection of resistance and virulence markers. It also facilitates the study of phylogenetic relationships of epidemic strains...
  31. doi request reprint Molecular fingerprinting of Staphylococcus aureus from bone and joint infections
    C Luedicke
    Medical Clinic and Policlinic I, University Hospital Dresden, Dresden, Germany
    Eur J Clin Microbiol Infect Dis 29:457-63. 2010
    ..aureus carriers and the possibility of endogenous infection in a high proportion of them. Therefore, the pre-operative screening and eradication of S. aureus in patients receiving total joint prosthetics should be considered...
  32. pmc Diversity of SCCmec Elements in Staphylococcus aureus as Observed in South-Eastern Germany
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene IMMH, Technische Universitat Dresden, Dresden, Germany
    PLoS ONE 11:e0162654. 2016
    ..The high degree of diversity of SCC elements even within so-called strains could be helpful for epidemiological typing. It also raises the question on scale and speed of the evolution of SCC elements. ..
  33. pmc Clonal replacement of epidemic methicillin-resistant Staphylococcus aureus strains in a German university hospital over a period of eleven years
    Nicole Albrecht
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany
    PLoS ONE 6:e28189. 2011
    ..Seven PVL-positive MRSA strains were found, but they remained rare during the study period accounting together for 2.7% of isolates...
  34. pmc Development of a rapid microarray-based DNA subtyping assay for the alleles of Shiga toxins 1 and 2 of Escherichia coli
    Lutz Geue
    Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Institute of Molecular Pathogenesis, Jena, Germany
    J Clin Microbiol 52:2898-904. 2014
    ..The number of the spotted probes on the microarrays can be increased by additional probes, such as for novel alleles, species markers, or resistance genes, should the need arise. ..
  35. doi request reprint Development and usage of protein microarrays for the quantitative measurement of Panton-Valentine leukocidin
    Bettina Stieber
    Alere Technologies GmbH, Jena, Germany Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany Electronic address
    Mol Cell Probes 28:123-32. 2014
    ..The method described herein allows rapid quantification of expressed proteins such as PVL in collections of clinical isolates in order to correlate with clinical or genotypic data with a potential for further parallelisation...
  36. pmc Fast DNA serotyping and antimicrobial resistance gene determination of salmonella enterica with an oligonucleotide microarray-based assay
    Sascha D Braun
    Alere Technologies GmbH, Jena, Germany
    PLoS ONE 7:e46489. 2012
    ..All were identified as Salmonella and 93 of 105 isolates (88.6%) were typed in full concordance with conventional serotyping. This microarray based assay is a powerful tool for serogenotyping...
  37. pmc Diversity of Staphylococcus aureus Isolates in European Wildlife
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene IMMH, Technical University of Dresden, Dresden, Germany
    PLoS ONE 11:e0168433. 2016
    ..The prevalence of S. aureus/MRSA in wildlife as well as its population structures in different wildlife host species warrants further investigation...
  38. pmc DNA-Microarray-based Genotyping of Clostridium difficile
    Darius Gawlik
    Institute for Medical Microbiology and Hygiene, Technische Universitat Dresden, Dresden, Germany
    BMC Microbiol 15:158. 2015
    ..A microarray was designed that included toxin genes (tcdA/B, cdtA/B), genes related to antimicrobial resistance, the slpA gene and additional variable genes...
  39. pmc Direct, Specific and Rapid Detection of Staphylococcal Proteins and Exotoxins Using a Multiplex Antibody Microarray
    Bettina Stieber
    Alere Technologies GmbH, Jena, Germany
    PLoS ONE 10:e0143246. 2015
    ..aureus strains and determine their resistances. However, there is a demand for multiplex routine diagnostic tests to directly detect staphylococcal toxins and proteins...
  40. pmc Population structure of Staphylococcus aureus from Trinidad & Tobago
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany Alere Technologies GmbH, Jena, Germany
    PLoS ONE 9:e89120. 2014
    ..The population structure of S. aureus isolates suggests an importation of strains from Africa, endemicity of PVL-positive MSSA (mainly CC8) and of ST239-MRSA-III, and a recent emergence of the PVL-positive CC8-MRSA-IV strain "USA300". ..
  41. pmc Rapid identification of carbapenemase genes in gram-negative bacteria with an oligonucleotide microarray-based assay
    Sascha D Braun
    Alere Technologies GmbH, Jena, Germany
    PLoS ONE 9:e102232. 2014
    ..This assay might be easily extended, adapted and transferred to point of care platforms enabling fast surveillance, rapid detection and appropriate early treatment of infections caused by multiresistant Gram-negative bacteria. ..
  42. pmc Rapid spoligotyping of Mycobacterium tuberculosis complex bacteria by use of a microarray system with automatic data processing and assignment
    Anke Ruettger
    Friedrich Loeffler Institut Federal Research Institute for Animal Health, Institute of Molecular Pathogenesis, Jena, Germany
    J Clin Microbiol 50:2492-5. 2012
    ..We have shown the assay's validity and suitability for direct typing from tissue and detecting new spoligotypes. Advantages of the microarray methodology include rapidity, ease of operation, automatic data processing, and affordability...
  43. doi request reprint Carbapenemase-producing Enterobacteriaceae: a 2-year surveillance in a hospital in Iaşi, Romania
    Sascha D Braun
    Alere Technologies GmbH, Jena, Germany
    Future Microbiol 11:391-401. 2016
    ..Limited information is currently available about the prevalence of carbapenemase-producing Enterobacteriaceae (CPE) in Romania...
  44. pmc DNA microarray-based typing of Streptococcus agalactiae isolates
    Heike Nitschke
    Institute for Medical Microbiology and Hygiene, Technische Universitat Dresden, Dresden, Germany Department of Obstetrics and Gynecology, Elblandklinikum Meißen, Meissen, Germany
    J Clin Microbiol 52:3933-43. 2014
    ..The arrays and typing scheme described here proved to be a convenient tool for genotyping large numbers of clinical/veterinary isolates and thus might help obtain insight into the epidemiology of S. agalactiae. ..
  45. doi request reprint Characterization of PVL-positive MRSA from Norway
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany Alere Technologies GmbH, Jena, Germany
    APMIS 122:580-4. 2014
    ..Our study corroborates the current practice of mandatory screening of patients and staff with travel histories, admissions or employment in healthcare institutions outside the Scandinavian countries or with known MRSA contacts...
  46. pmc Staphylococcus aureus in vitro secretion of alpha toxin (hla) correlates with the affiliation to clonal complexes
    Stefan Monecke
    Alere Technologies GmbH, Jena, Germany Institute for Medical Microbiology and Hygiene, Technische Universitat Dresden, Dresden, Germany
    PLoS ONE 9:e100427. 2014
    ..There was no correlation between alpha toxin yield and clinical course of the disease, or between alpha toxin yield and host species. ..
  47. pmc Molecular typing of MRSA and of clinical Staphylococcus aureus isolates from Iaşi, Romania
    Stefan Monecke
    Institute for Medical Microbiology and Hygiene, Medizinische Fakultät Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany Alere Technologies GmbH, Jena, Germany
    PLoS ONE 9:e97833. 2014
    ..Although this study provides only a snapshot of S. aureus/MRSA epidemiology in Romania, it confirms the high burden of MRSA and PVL on Romanian healthcare settings. ..
  48. doi request reprint Application of protein arraytubes to bacteria, toxin, and biological warfare agent detection
    Ralf Ehricht
    CLONDIAG Chip Technologies, Jena, Germany
    Methods Mol Biol 509:85-105. 2009
    ..This approach makes it possible to test every combination, allowing to find the optimal pair of detection/capture antibody...
  49. ncbi request reprint Development and evaluation of a real-time PCR assay for detection of Pneumocystis jiroveci
    D Bandt
    Institut fur Virologie, Medizinisch Theoretisches Zentrum, Dresden, Germany
    Transpl Infect Dis 9:196-202. 2007
    ..Differentiation of carriage, asymptomatic reactivation, and clinical infection as well as normalized quantification by calculating the ratio of Pneumocystis DNA to human DNA are discussed...
  50. ncbi request reprint A case of peritonitis caused by Rhizopus microsporus
    Stefan Monecke
    Mycoses 49:139-42. 2006
    ..Despite aggressive surgical treatment, intravenous therapy with amphotericin B and topical administration of Lavasept (polyhexamethylenbiguanide), the patient died...