Cinzia Fatini

Summary

Publications

  1. doi request reprint Lipoprotein (a) [Lp(a)]: a possible link between migraine and stroke
    Fatini Cinzia
    Department of Medical and Surgical Critical Care, the Thrombosis Centre, University of Florence, Florence, Italy
    Transl Res 153:44-7. 2009
  2. ncbi request reprint AGT and ACE genes influence classic mitral valve prolapse predisposition in Marfan patients
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, University of Florence, Italy
    Int J Cardiol 123:293-7. 2008
  3. ncbi request reprint Lone and secondary nonvalvular atrial fibrillation: role of a genetic susceptibility
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Viale Morgagni 85, 50134 Florence, Italy
    Int J Cardiol 120:59-65. 2007
  4. ncbi request reprint Endothelial nitric oxide synthase gene influences the risk of pre-eclampsia, the recurrence of negative pregnancy events, and the maternal-fetal flow
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Section of Clinical Medicine and Cardiology, University of Florence, Florence, Italy
    J Hypertens 24:1823-9. 2006
  5. ncbi request reprint Hemorheologic profile in systemic sclerosis: role of NOS3 -786T > C and 894G >T polymorphisms in modulating both the hemorheologic parameters and the susceptibility to the disease
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Arthritis Rheum 54:2263-70. 2006
  6. ncbi request reprint Analysis of minK and eNOS genes as candidate loci for predisposition to non-valvular atrial fibrillation
    Cinzia Fatini
    Department of Medical and Surgical Critical Care Thrombosis Centre, Azienda Ospedaliero Universitaria, University of Florence, Viale Morgagni 85, 50134, Italy
    Eur Heart J 27:1712-8. 2006
  7. ncbi request reprint eNOS gene affects red cell deformability: role of T-786C, G894T, and 4a/4b polymorphisms
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Section of Clinical Medicine and Cardiology, Thrombosis Centre, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Clin Appl Thromb Hemost 11:481-8. 2005
  8. ncbi request reprint Endothelial nitric oxide synthase -786T>C, but not 894G>T and 4a4b, polymorphism influences plasma homocysteine concentrations in persons with normal vitamin status
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy
    Clin Chem 51:1159-64. 2005
  9. doi request reprint Multilocus analysis in candidate genes ACE, AGT, and AGTR1 and predisposition to peripheral arterial disease: role of ACE D/-240T haplotype
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    J Vasc Surg 50:1399-404. 2009
  10. doi request reprint Platelet aggregability is modulated by eNOS locus in non-type 2 diabetic patients with acute coronary syndrome
    C Fatini
    Department of Medical and Surgical Critical Care, Azienda Ospedaliero Universitaria Careggi, University of Florence, Florence, Italy
    Nutr Metab Cardiovasc Dis 21:11-7. 2011

Collaborators

Detail Information

Publications53

  1. doi request reprint Lipoprotein (a) [Lp(a)]: a possible link between migraine and stroke
    Fatini Cinzia
    Department of Medical and Surgical Critical Care, the Thrombosis Centre, University of Florence, Florence, Italy
    Transl Res 153:44-7. 2009
    ..The current study suggested evidence of high Lp(a) concentrations affecting migraines, possibly hypothesizing a novel link between migraine and stroke...
  2. ncbi request reprint AGT and ACE genes influence classic mitral valve prolapse predisposition in Marfan patients
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, University of Florence, Italy
    Int J Cardiol 123:293-7. 2008
    ....
  3. ncbi request reprint Lone and secondary nonvalvular atrial fibrillation: role of a genetic susceptibility
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Viale Morgagni 85, 50134 Florence, Italy
    Int J Cardiol 120:59-65. 2007
    ..The aim of this study was to investigate the role of the ACE I/D polymorphism in relation to the different clinical forms of AF, lone and secondary nonvalvular atrial fibrillation (NVAF)...
  4. ncbi request reprint Endothelial nitric oxide synthase gene influences the risk of pre-eclampsia, the recurrence of negative pregnancy events, and the maternal-fetal flow
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Section of Clinical Medicine and Cardiology, University of Florence, Florence, Italy
    J Hypertens 24:1823-9. 2006
    ..An inadequate nitric oxide availability related to polymorphisms in the endothelial nitric oxide synthase gene (eNOS) might predispose to the disease...
  5. ncbi request reprint Hemorheologic profile in systemic sclerosis: role of NOS3 -786T > C and 894G >T polymorphisms in modulating both the hemorheologic parameters and the susceptibility to the disease
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Viale Morgagni 85, 50134 Florence, Italy
    Arthritis Rheum 54:2263-70. 2006
    ..We undertook this study to investigate the hemorheologic profile in SSc and the role of NOS3 polymorphisms in modulating the hemorheologic status of SSc patients...
  6. ncbi request reprint Analysis of minK and eNOS genes as candidate loci for predisposition to non-valvular atrial fibrillation
    Cinzia Fatini
    Department of Medical and Surgical Critical Care Thrombosis Centre, Azienda Ospedaliero Universitaria, University of Florence, Viale Morgagni 85, 50134, Italy
    Eur Heart J 27:1712-8. 2006
    ..We evaluated the role of eNOS -786T>C, 894G>T, 4a/4b and of minK S38G polymorphisms as predisposing factors to non-valvular atrial fibrillation (NVAF)...
  7. ncbi request reprint eNOS gene affects red cell deformability: role of T-786C, G894T, and 4a/4b polymorphisms
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Section of Clinical Medicine and Cardiology, Thrombosis Centre, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Clin Appl Thromb Hemost 11:481-8. 2005
    ..9, p<0.0001). Our study documented that eNOS gene affects the red blood cell deformability, so possibly contributing to ISSHL, which may represent a suitable model of microcirculatory disorder...
  8. ncbi request reprint Endothelial nitric oxide synthase -786T>C, but not 894G>T and 4a4b, polymorphism influences plasma homocysteine concentrations in persons with normal vitamin status
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy
    Clin Chem 51:1159-64. 2005
    ..The aim of this study was to investigate the role of endothelial nitric oxide synthase (eNOS) -786T>C, 894G>T, and 4a4b polymorphisms in influencing Hcy concentrations...
  9. doi request reprint Multilocus analysis in candidate genes ACE, AGT, and AGTR1 and predisposition to peripheral arterial disease: role of ACE D/-240T haplotype
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    J Vasc Surg 50:1399-404. 2009
    ..This study investigated four polymorphisms in angiotensinogen (AGT), angiotensin converting enzyme (ACE), and angiotensin II receptor type 1 (AGTR1), genes of RAS, in both predicting PAD and modulating the severity of the disease...
  10. doi request reprint Platelet aggregability is modulated by eNOS locus in non-type 2 diabetic patients with acute coronary syndrome
    C Fatini
    Department of Medical and Surgical Critical Care, Azienda Ospedaliero Universitaria Careggi, University of Florence, Florence, Italy
    Nutr Metab Cardiovasc Dis 21:11-7. 2011
    ....
  11. doi request reprint eNOS gene influences platelet phenotype in acute coronary syndrome patients on dual antiplatelet treatment
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Department of Heart and Vessels, Azienda Ospedaliero Universitaria Careggi, University of Florence, 50134 Florence, Italy
    Platelets 20:548-54. 2009
    ..02). This study evidences a role for eNOS gene in moderately, but significantly, modulating platelet phenotype in a high-risk population on dual antiplatelet treatment...
  12. ncbi request reprint Influence of endothelial nitric oxide synthase gene polymorphisms (G894T, 4a4b, T-786C) and hyperhomocysteinemia on the predisposition to acute coronary syndromes
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Section of Clinical Medicine and Cardiology, Thrombosis Centre, Azienda Ospedaliera Careggi, Florence, Italy
    Am Heart J 147:516-21. 2004
    ..In this study we investigated the role of endothelial nitric oxide synthase (eNOS) polymorphisms as predisposing factors to acute coronary syndromes (ACS)...
  13. doi request reprint S38G single-nucleotide polymorphism at the KCNE1 locus is associated with heart failure
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy
    Heart Rhythm 7:363-7. 2010
    ..Experimental data demonstrated a higher KCNE1 expression in heart failure (HF)...
  14. doi request reprint eNOS and ACE genes influence peripheral arterial disease predisposition in smokers
    Elena Sticchi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    J Vasc Surg 52:97-102.e1. 2010
    ..In this study, we evaluated the role of eNOS-786T>C, -894G>T and 4a/4b polymorphisms as markers of PAD per se and in the presence of the ACE D allele in patients previously investigated...
  15. doi request reprint ACE and TGFBR1 genes interact in influencing the susceptibility to abdominal aortic aneurysm
    Laura Lucarini
    Department of Medical and Surgical Critical Care, University of Florence, Thrombosis Centre, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Atherosclerosis 202:205-10. 2009
    ..01]. This study, which demonstrates an interaction between ACE and TGFBR1 genes in predisposing to AAA, may provide further information on the mechanisms contributing to AAA susceptibility, and offer a topic for future larger studies...
  16. ncbi request reprint Low-molecular-weight heparin lowers the recurrence rate of preeclampsia and restores the physiological vascular changes in angiotensin-converting enzyme DD women
    Giorgio Mello
    Department of Gynecology, Perinatology and Human Reproduction, University of Florence, Viale GB Morgagni 85, 50134 Florence, Italy
    Hypertension 45:86-91. 2005
    ..LMWH reduces the recurrence of preeclampsia, of negative outcomes, and the resistance of uteroplacental flow, and also prevents maternal blood pressure increase in ACE DD homozygote women with a previous history of preeclampsia...
  17. pmc Role of C677T and A1298C MTHFR, A2756G MTR and -786 C/T eNOS gene polymorphisms in atrial fibrillation susceptibility
    Betti Giusti
    Department of Medical and Surgical Critical Care and Center of Research, Transfer and High Education, DENOthe, University of Florence, Florence, Italy
    PLoS ONE 2:e495. 2007
    ..Hyperhomocysteinemia has been suggested to play a role in the NonValvular Atrial Fibrillation (NVAF) pathogenesis. Polymorphisms in genes coding for homocysteine (Hcy) metabolism enzymes may be associated with hyperhomocysteinemia and NVAF...
  18. doi request reprint Association between polymorphisms of the renin angiotensin system and carotid stenosis
    Elena Sticchi
    Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy
    J Vasc Surg 54:467-73. 2011
    ....
  19. doi request reprint ACE insertion/deletion, but not -240A>T polymorphism, modulates the severity in heart failure
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Thrombosis Centre and Centre for the Study at Molecular and Clinical Level of Chronic, University of Florence, Italy
    J Investig Med 56:1004-10. 2008
    ..In this study, we investigated the role of ACE I/D and -240A>T polymorphisms in influencing both severity and clinical outcomes in patients with heart failure, according to New York Heart Association (NYHA) class...
  20. ncbi request reprint Clinical haemorheology and microcirculation
    Lucia Mannini
    Dipartimento di Area Critica Medico Chirurgica, Sez Clinica Medica Generale e Cliniche Specialistiche, Centro Trombosi, Universita di Firenze, Viale Morgagni 85, 50134 Firenze, Italy
    Ann Ist Super Sanita 43:144-55. 2007
    ..These results suggest that hyperviscosity, either determined by genetic susceptibility or not, can be involved in the pathophysiology of these clinical disorders and can be the target of new therapeutic strategies...
  21. doi request reprint ACE gene in pregnancy complications: Insights into future vascular risk
    Cinzia Fatini
    a Department of Experimental and Clinical Medicine, University of Florence, Thrombosis Centre, Largo Brambilla, Florence, Italy
    Hypertens Pregnancy 35:62-72. 2016
    ..We performed this study in order to search for a common genetic background shared by women with a history of PMPC and vascular disorders, due to their common pathophysiologic pathway of endothelial dysfunction...
  22. ncbi request reprint Maternal-fetal flow, negative events, and preeclampsia: role of ACE I/D polymorphism
    Giorgio Mello
    Department of Gynecology, Perinatology, and Human Reproduction, University of Florence, Florence, Italy
    Hypertension 41:932-7. 2003
    ..The current study shows that the ACE I/D polymorphism affects uteroplacental and umbilical flows and the recurrence of an adverse pregnancy outcome in women with history of preeclampsia...
  23. ncbi request reprint Angiotensin-converting enzyme and endothelial nitric oxide synthase polymorphisms in patients with atrial fibrillation
    Francesca Gensini
    Department of Clinical Physiopathology, Unit of Medical Genetics, University of Florence, Italy
    Pacing Clin Electrophysiol 26:295-8. 2003
    ..The results suggest a possible role of ACE DD genotype as a predisposing factor to AF and a pathophysiological mechanism of ACE inhibition in reducing the incidence of AF in patients with left ventricular dysfunction...
  24. ncbi request reprint High prevalence of polymorphisms of angiotensin-converting enzyme (I/D) and endothelial nitric oxide synthase (Glu298Asp) in patients with systemic sclerosis
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Section of Clinical Medicine and Cardiology, University of Florence, Florence, Italy
    Am J Med 112:540-4. 2002
    ..The aim of our study was to investigate the effects of ACE insertion/deletion (I/D) and endothelial nitric oxide synthase (eNOS) Glu298Asp (G894-->T) and T-786-->C polymorphisms in patients with systemic sclerosis...
  25. ncbi request reprint Impaired fibrinolysis in retinal vein occlusion: a role for genetic determinants of PAI-1 levels
    Anna Maria Gori
    Department of Surgical and Medical Critical Care, Thrombosis Center, University of Florence, Viale Morgagni, 85, 50134 Florence, Italy
    Thromb Haemost 92:54-60. 2004
    ....
  26. ncbi request reprint High-speed detection of the G894T polymorphism in exon 7 of the eNOS gene by real-time fluorescence PCR with the Light-Cycler
    Elena Sticchi
    Department of Clinical Physiopathology, Unit of Medical Genetics, University of Florence, Florence, Italy
    Biochem Genet 42:121-7. 2004
    ..This methodology is considered more accurate and less time-consuming than conventional PCR-RFLP assay. To validate this technique we genotyped 270 healthy subjects. The results were consistent with those obtained from PCR-RFLP assay...
  27. doi request reprint Peripheral-arterial tonometry for assessing endothelial function in relation to dietary habits
    Gabriele Cioni
    Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
    J Investig Med 61:867-71. 2013
    ....
  28. ncbi request reprint Fish intake and LPA 93C>T polymorphism: gene-environment interaction in modulating lipoprotein (a) concentrations
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Centre, University of Florence, Italy
    Atherosclerosis 195:e147-54. 2007
    ..In conclusion, this study reported a significant interaction of daily fish intake and LPA 93C>T polymorphism in decreasing Lp(a) concentrations...
  29. ncbi request reprint eNOS G894T polymorphism as a mild predisposing factor for abdominal aortic aneurysm
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, University of Florence, Thrombosis Centre, Italy
    J Vasc Surg 42:415-9. 2005
    ..No information is available about the influence of the eNOS gene T-786C, G894T, and 4a/4b polymorphisms in the susceptibility to the disease...
  30. doi request reprint A genetic variation located in the promoter region of the UPAR (CD87) gene is associated with the vascular complications of systemic sclerosis
    Mirko Manetti
    University of Florence and Excellence Centre for Research, Transfer and High Education on Chronic, Inflammatory, Degenerative and Neoplastic Disorders for the Development of Novel Therapies, Florence, Italy
    Arthritis Rheum 63:247-56. 2011
    ..We undertook this study to investigate whether UPAR gene promoter polymorphisms might be associated with SSc phenotypes in the European Caucasian population...
  31. ncbi request reprint Protein Z levels and prognosis in patients with acute coronary syndromes
    Francesco Sofi
    Department of Medical and Surgical Critical Care, Thrombosis Center, University of Florence, Florence, Italy
    Clin Chem Lab Med 44:1098-102. 2006
    ..The aims of this study were to test changes in protein Z and their association with outcome at 1-year follow-up in 193 (150 male, 43 female) patients with ACS...
  32. doi request reprint Fibrinolysis alterations in infertile women during controlled ovarian stimulation: influence of BMI and genetic components
    Elena Sticchi
    Department of Medical and Surgical Critical Care, Thrombosis Center, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Thromb Res 130:919-24. 2012
    ....
  33. doi request reprint Unexplained infertility: association with inherited thrombophilia
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Thrombosis Center, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Thromb Res 129:e185-8. 2012
    ..Attention is being paid to the association between inherited thrombophilia and infertility causes. In this study we investigated the prevalence of inherited thrombophilia according to infertility causes...
  34. doi request reprint Improvement in ACE I/D polymorphism detection
    Paola Bolli
    Department of Medical and Surgical Critical Care and Center of Research, Transfer and High Education, DENOthe, University of Florence, Italy
    J Renin Angiotensin Aldosterone Syst 12:129-32. 2011
    ..Our experiments provide evidence that, by using the Nanogen stepdown method, the DD mistyping was markedly decreased, thus representing a useful tool suitable for performing large-scale screening or research...
  35. ncbi request reprint Risk of bleeding in very old atrial fibrillation patients on warfarin: relationship with ageing and CHADS2 score
    Daniela Poli
    Department of Critical Care Medicine, Thrombosis Centre, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy
    Thromb Res 121:347-52. 2007
    ..In atrial fibrillation (AF) patients, age >or=75 years is one of the major risk factors for stroke. However, it is not clear if an upper limit for the indication to OAT exists...
  36. ncbi request reprint Angiotensin-converting enzyme in systemic sclerosis: from endothelial injury to a genetic polymorphism
    Serena Guiducci
    Division of Medicine I and Rheumatology, Villa Monna Tessa, Viale Pieraccini 18, 50139, Florence, Italy
    Ann N Y Acad Sci 1069:10-9. 2006
    ....
  37. doi request reprint Is tissue factor pathway inhibitor a marker of procoagulable status in healthy infertile women undergoing ovarian stimulation for assisted reproduction?
    Ilaria Romagnuolo
    aDepartment of Clinical and Experimental Medicine, Thrombosis Center, University of Florence, Azienda Ospedaliero Universitaria Careggi bFiorgen Foundation cDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Blood Coagul Fibrinolysis 25:254-8. 2014
    ..Nevertheless, the small number of individuals investigated might influence the relevance of our results. ..
  38. ncbi request reprint Vascular injury in systemic sclerosis: angiotensin-converting enzyme insertion/deletion polymorphism
    Cinzia Fatini
    Department of Medicine, Section of Rheumatology, University of Florence, Villa Monna Tessa, Viale Pieraccini 18, 50122 Firenze, Italy
    Curr Rheumatol Rep 6:149-55. 2004
    ..The discrepancy between the high prevalence of D allele and reduced ACE plasma levels in SSc demonstrate the lack of knowledge on the regulation and function of renin-angiotensin system in SSc...
  39. doi request reprint Detrimental effects of niacin/laropiprant on microvascular reactivity and red cell deformability in patients with elevated lipoprotein(a) levels
    Gabriele Cioni
    Department of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, 50132, Florence, Italy
    J Thromb Thrombolysis 41:433-5. 2016
    ..In turn, these effects might explain, at least in part, the lack of a clinical net benefit of niacin/laropiprant in the trial...
  40. doi request reprint Searching for a common mechanism for placenta-mediated pregnancy complications and cardiovascular disease: role of lipoprotein(a)
    Ilaria Romagnuolo
    Department of Experimental and Clinical Medicine, Thrombosis Center, University of Florence, Florence, Italy
    Fertil Steril 105:1287-1293.e3. 2016
    ....
  41. doi request reprint Hemorheologic profile in healthy women undergoing controlled ovarian stimulation
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Thrombosis Center, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Fertil Steril 95:327-9. 2011
    ....
  42. doi request reprint Diabetes and sex: from pathophysiology to personalized medicine
    Rosanna Abbate
    Department of Medical and Surgical Critical Care, University of Florence, SOD Atherothrombotic Diseases, AOU Careggi, Viale Morgagni, 85, 50134, Florence, Italy
    Intern Emerg Med 7:S215-9. 2012
    ..In relation to diabetes, the sex-related difference in platelet activity and platelet inhibitory response to anti-aggregating therapy, reported in the general population, was observed also in diabetic women...
  43. doi request reprint Association of a functional polymorphism in the matrix metalloproteinase-12 promoter region with systemic sclerosis in an Italian population
    Mirko Manetti
    Department of Anatomy, Histology and Forensic Medicine, University of Florence, Viale G B Morgagni 85, I 50134, Florence, Italy
    J Rheumatol 37:1852-7. 2010
    ..To investigate the possible implication of the matrix metalloproteinase-12 (MMP-12) gene in the genetic predisposition to systemic sclerosis (SSc) susceptibility and clinical phenotype...
  44. doi request reprint Refractory hyperaldosteronism in heart failure is associated with plasma renin activity and angiotensinogen polymorphism
    Giuseppe Vergaro
    aFondazione Toscana Gabriele Monasterio, Pisa bDepartment of Medical and Surgical Critical Care, University of Florence cFondazione Don Carlo Gnocchi ONLUS, Centro S Maria degli Ulivi IRCCS, Florence, Italy dINSERM, Centre d Investigations Cliniques 9501, Vandoeuvre les Nancy, France and Université de Lorraine, France and CHU de Nancy, Nancy, France and INSERM U1116, Vandoeuvre les Nancy, France eScuola Superiore Sant Anna, Pisa, Italy
    J Cardiovasc Med (Hagerstown) 16:416-22. 2015
    ..Our aim was to identify which factors, either genetic or nongenetic, are associated with refractory hyperaldosteronism...
  45. doi request reprint Gender and anti-thrombotic therapy: from biology to clinical implications
    Rossella Marcucci
    Department of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, 50050, Florence, Italy
    J Cardiovasc Transl Res 7:72-81. 2014
    ..In summary, there are some gender-related aspects of guidance in the complex spectrum of the net clinical benefit related to antithrombotic treatment. ..
  46. doi request reprint Evidence for caveolin-1 as a new susceptibility gene regulating tissue fibrosis in systemic sclerosis
    Mirko Manetti
    Department of Anatomy, Histology and Forensic Medicine, University of Florence, Florence, Italy
    Ann Rheum Dis 71:1034-41. 2012
    ..The aim of the study was to analyse the possible association of CAV1 gene single nucleotide polymorphisms (SNP) with SSc...
  47. doi request reprint Relationship among endothelial response to hyperemia, bone marrow-derived progenitor cells, and parathyroid hormone in renal transplantation
    Cinzia Fatini
    Department of Medical and Surgical Critical Care, Thrombosis Center, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Transplantation 93:835-41. 2012
    ..We evaluated the relationship between endothelial response to hyperemia and circulating progenitor cells (CPCs) and endothelial progenitor cells (EPCs) PTH, and genetic parameters in RTRs...
  48. ncbi request reprint ACE I/D polymorphism and cardiac adaptations in adolescent athletes
    Marta Rizzo
    Section of Sports Medicine, Department of Medical and Surgical Critical Care, University of Florence, Italy
    Med Sci Sports Exerc 35:1986-90. 2003
    ..The aim of this cross-sectional study was to determine whether there is a correlation between left ventricular hypertrophy (LVH) and angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism in adolescent athletes...
  49. ncbi request reprint LPA +93C>T and +121G>A polymorphisms detection by electronic microchip technology
    Elena Sticchi
    Fondazione Don Carlo Gnocchi, ONLUS, S Maria degli Ulivi IRCCS, Firenze, Italy
    Mol Genet Metab 91:79-84. 2007
    ..In particular, this Technology allows the analysis of polymorphisms at the LPA locus, able to modulate the levels of Lp(a), a relevant marker of atherosclerosis...
  50. doi request reprint Autoantibodies against β1-Adrenergic Receptors: Response to Cardiac Resynchronization Therapy and Renal Function
    Antonio Michelucci
    Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
    Pacing Clin Electrophysiol 39:65-72. 2016
    ..Autoantibodies specific for the β1-adrenergic (β1-AAbs) and muscarinic (M2-AAbs) receptors are found in patients with chronic heart failure (HF) of various etiologies...
  51. pmc Genetics of cardiovascular disease
    Rosanna Abbate
    Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy Thrombosis Centre, Azienda Ospedaliero Universitaria Careggi, Florence, Italy Centre for the Study at Molecular and Clinical Level of Chronic, Degenerative and Neoplastic Diseases to Develop Novel Therapies, University of Florence, Florence, Italy
    Clin Cases Miner Bone Metab 5:63-6. 2008
    ..This approach contributes to finely investigate the gene-gene and gene-environment interactions in CVD, and to look for the involvement of genetic polymorphisms in drug response...
  52. ncbi request reprint Protein Z gene polymorphisms (intron F 79 G>A; -13 A>G) are not associated with acute coronary syndromes
    Francesca Cesari
    Thromb Haemost 96:98-9. 2006
  53. ncbi request reprint Genetic susceptibility to atrial fibrillation (AF) in patients with congestive heart failure
    Cinzia Fatini
    Heart Rhythm 3:1395; author reply 1395. 2006