Mikael Brosché

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. pmc Salicylic acid signaling inhibits apoplastic reactive oxygen species signaling
    Enjun Xu
    Division of Plant Biology, Department of Biosciences, University of Helsinki, P, O, Box 65 Viikinkaari 1, FI 00014 Helsinki, Finland
    BMC Plant Biol 14:155. 2014
  2. pmc Low antioxidant concentrations impact on multiple signalling pathways in Arabidopsis thaliana partly through NPR1
    Mikael Brosché
    Department of Biosciences, University of Helsinki, Helsinki, Finland
    J Exp Bot 63:1849-61. 2012
  3. pmc Gene expression and metabolite profiling of Populus euphratica growing in the Negev desert
    Mikael Brosché
    Plant Biology, Department of Biological and Environmental Sciences, University of Helsinki, P, O, Box 65, Viikinkaari 1, FIN 00014 Helsinki, Finland
    Genome Biol 6:R101. 2005
  4. doi request reprint Nitric oxide modulates ozone-induced cell death, hormone biosynthesis and gene expression in Arabidopsis thaliana
    Reetta Ahlfors
    Plant Biology, Department of Biological and Environmental Sciences, University of Helsinki, PO Box 65 Viikinkaari 1, FI 00014 Helsinki, Finland Institute of Technology, University of Tartu, Nooruse 1, Tartu 50411, Estonia
    Plant J 58:1-12. 2009
  5. pmc Ozone-induced programmed cell death in the Arabidopsis radical-induced cell death1 mutant
    Kirk Overmyer
    Department of Biological and Environmental Sciences, University of Helsinki, FIN 00014 Helsinki, Finland
    Plant Physiol 137:1092-104. 2005
  6. pmc Apoplastic reactive oxygen species transiently decrease auxin signaling and cause stress-induced morphogenic response in Arabidopsis
    Tiina Blomster
    Division of Plant Biology, Department of Biosciences, University of Helsinki, FI 00014 Helsinki, Finland
    Plant Physiol 157:1866-83. 2011
  7. doi request reprint Unequally redundant RCD1 and SRO1 mediate stress and developmental responses and interact with transcription factors
    Pinja Jaspers
    Plant Biology, Department of Biological and Environmental Sciences, Viikki Biocenter, University of Helsinki, Helsinki, Finland
    Plant J 60:268-79. 2009
  8. pmc PYR/RCAR receptors contribute to ozone-, reduced air humidity-, darkness-, and CO2-induced stomatal regulation
    Ebe Merilo
    Institute of Technology, University of Tartu, Tartu 50411, Estonia
    Plant Physiol 162:1652-68. 2013
  9. doi request reprint Ozone-triggered rapid stomatal response involves the production of reactive oxygen species, and is controlled by SLAC1 and OST1
    Triin Vahisalu
    Division of Plant Biology, Department of Biosciences, University of Helsinki, PO Box 65 Viikinkaari 1, FI 00014 Helsinki, Finland
    Plant J 62:442-53. 2010
  10. doi request reprint RCD1-DREB2A interaction in leaf senescence and stress responses in Arabidopsis thaliana
    Julia P Vainonen
    Plant Biology, Department of Biosciences, Viikki Biocenter, University of Helsinki, Finland
    Biochem J 442:573-81. 2012

Collaborators

  • Kirk Overmyer
  • Michael Wrzaczek
  • Pedro J Aphalo
  • Pinja Jaspers
  • Hiroaki Fujii
  • Julian I Schroeder
  • Erwin Dreyer
  • Kalle Kilk
  • Johanna Leppälä
  • Dirk Inze
  • Silke Robatzek
  • Radhika Desikan
  • Jason J Wargent
  • Gareth I Jenkins
  • Stephen Rudd
  • Franziska Turck
  • Jaakko Kangasjärvi
  • Enjun Xu
  • Luis O Morales
  • Hannes Kollist
  • Lauri Vaahtera
  • Reetta Ahlfors
  • Ebe Merilo
  • Fuqiang Cui
  • Nina Sipari
  • Triin Vahisalu
  • Julia P Vainonen
  • Kristiina Laanemets
  • Jarkko Salojärvi
  • Riitta Tegelberg
  • Eve Kaurilind
  • Niina Idänheimo
  • Anders V Lindfors
  • Ake Strid
  • Ove Lindgren
  • Tiina Blomster
  • Markku Keinänen
  • Noriyuki Nishimura
  • Anders Lindfors
  • Yong Fei Wang
  • Airi Lamminmäki
  • Heino Moldau
  • Jari P T Valkonen
  • Matleena Punkkinen
  • Mikko T Lehtonen
  • Ali Amiryousefi
  • Arnd G Heyer
  • Dirk K Hincha
  • Hanna Hõrak
  • Ari Pekka Mähönen
  • Indrek Jõesaar
  • Riccardo Siligato
  • Adrien Gauthier
  • Shaowu Xue
  • Julia Vainonen
  • Saijun Tang
  • Pedro L Rodriguez
  • Honghong Hu
  • Daniel Caddell
  • Miguel Gonzalez-Guzman
  • Stephen Lee
  • Juyou Wu
  • Ingmar Tulva
  • Ursel Soomets
  • Liina Jakobson
  • Ramesha A Reddy
  • Sari Siipola
  • Irina Puzõrjova
  • Martin Lepiku
  • Priit Pechter
  • Mart Loog
  • Yuh Shuh Wang
  • Ervin Valk
  • Wai Yin Chan
  • Gabriel Valerio
  • Dierk Scheel
  • Enric Belles-Boix
  • E Tapio Palva
  • Saara Lång
  • Violetta Macioszek
  • Mirva Piippo
  • Hannele Tuominen
  • Airi Tauriainen
  • Jason Rudd
  • Rita Schlichting

Detail Information

Publications34

  1. pmc Salicylic acid signaling inhibits apoplastic reactive oxygen species signaling
    Enjun Xu
    Division of Plant Biology, Department of Biosciences, University of Helsinki, P, O, Box 65 Viikinkaari 1, FI 00014 Helsinki, Finland
    BMC Plant Biol 14:155. 2014
    ..Until recently, most studies on signal interactions have focused on phytohormone interaction, such as the antagonistic relationship between salicylic acid (SA)-jasmonic acid and cytokinin-auxin...
  2. pmc Low antioxidant concentrations impact on multiple signalling pathways in Arabidopsis thaliana partly through NPR1
    Mikael Brosché
    Department of Biosciences, University of Helsinki, Helsinki, Finland
    J Exp Bot 63:1849-61. 2012
    ..Overall, low ascorbic acid concentrations mostly led to opposite phenotypes to low glutathione concentrations, and both antioxidants interacted with SA and JA signalling pathways...
  3. pmc Gene expression and metabolite profiling of Populus euphratica growing in the Negev desert
    Mikael Brosché
    Plant Biology, Department of Biological and Environmental Sciences, University of Helsinki, P, O, Box 65, Viikinkaari 1, FIN 00014 Helsinki, Finland
    Genome Biol 6:R101. 2005
    ..euphratica trees. In addition, we identified several metabolites in desert-grown P. euphratica trees...
  4. doi request reprint Nitric oxide modulates ozone-induced cell death, hormone biosynthesis and gene expression in Arabidopsis thaliana
    Reetta Ahlfors
    Plant Biology, Department of Biological and Environmental Sciences, University of Helsinki, PO Box 65 Viikinkaari 1, FI 00014 Helsinki, Finland Institute of Technology, University of Tartu, Nooruse 1, Tartu 50411, Estonia
    Plant J 58:1-12. 2009
    ..In summary, NO is an important signalling molecule in the response to O₃...
  5. pmc Ozone-induced programmed cell death in the Arabidopsis radical-induced cell death1 mutant
    Kirk Overmyer
    Department of Biological and Environmental Sciences, University of Helsinki, FIN 00014 Helsinki, Finland
    Plant Physiol 137:1092-104. 2005
    ..Furthermore, mitogen-activated protein kinases showed differential activation patterns in rcd1 and Columbia. Taken together, these results directly demonstrate the induction of PCD by O(3)...
  6. pmc Apoplastic reactive oxygen species transiently decrease auxin signaling and cause stress-induced morphogenic response in Arabidopsis
    Tiina Blomster
    Division of Plant Biology, Department of Biosciences, University of Helsinki, FI 00014 Helsinki, Finland
    Plant Physiol 157:1866-83. 2011
    ..Altered leaf shape of tir1 afb2 suggests that auxin was a negative regulator of stress-induced morphogenic response in the rosette...
  7. doi request reprint Unequally redundant RCD1 and SRO1 mediate stress and developmental responses and interact with transcription factors
    Pinja Jaspers
    Plant Biology, Department of Biological and Environmental Sciences, Viikki Biocenter, University of Helsinki, Helsinki, Finland
    Plant J 60:268-79. 2009
    ..Full genome array analysis indicated that in many cases targets of these transcription factors have altered expression in the rcd1 but not the sro1 mutant. Taken together RCD1 and SRO1 are required for proper plant development...
  8. pmc PYR/RCAR receptors contribute to ozone-, reduced air humidity-, darkness-, and CO2-induced stomatal regulation
    Ebe Merilo
    Institute of Technology, University of Tartu, Tartu 50411, Estonia
    Plant Physiol 162:1652-68. 2013
    ..Thus, we show that PYR/RCAR receptors play an important role for the whole-plant stomatal adjustments and responses to low humidity, darkness, and O3 and are involved in responses to elevated CO2. ..
  9. doi request reprint Ozone-triggered rapid stomatal response involves the production of reactive oxygen species, and is controlled by SLAC1 and OST1
    Triin Vahisalu
    Division of Plant Biology, Department of Biosciences, University of Helsinki, PO Box 65 Viikinkaari 1, FI 00014 Helsinki, Finland
    Plant J 62:442-53. 2010
    ..The absence of the RTD in the dominant-negative mutants abi1-1 and abi2-1 also suggested a regulatory role for the protein phosphatases ABI1 and ABI2 in the ROS-induced activation of the S-type anion channel...
  10. doi request reprint RCD1-DREB2A interaction in leaf senescence and stress responses in Arabidopsis thaliana
    Julia P Vainonen
    Plant Biology, Department of Biosciences, Viikki Biocenter, University of Helsinki, Finland
    Biochem J 442:573-81. 2012
    ..In addition RCD1 is rapidly degraded during heat stress, thus our results suggest that removal of RCD1 protein or the loss of the interaction domain in DREB2A appears to be required for proper DREB2A function under stress conditions...
  11. pmc Transcriptional regulation of the CRK/DUF26 group of receptor-like protein kinases by ozone and plant hormones in Arabidopsis
    Michael Wrzaczek
    Plant Biology Division, Department of Biosciences, University of Helsinki, Helsinki, Finland
    BMC Plant Biol 10:95. 2010
    ..Despite the vast number of RLKs present in plants, however, only a few of them have been functionally characterized...
  12. pmc Mutations in the SLAC1 anion channel slow stomatal opening and severely reduce K+ uptake channel activity via enhanced cytosolic [Ca2+] and increased Ca2+ sensitivity of K+ uptake channels
    Kristiina Laanemets
    Institute of Technology, University of Tartu, 50411, Tartu, Estonia
    New Phytol 197:88-98. 2013
    ....
  13. pmc Multiple roles for UV RESISTANCE LOCUS8 in regulating gene expression and metabolite accumulation in Arabidopsis under solar ultraviolet radiation
    Luis O Morales
    Division of Plant Biology, Department of Biosciences, University of Helsinki, FI 00014 Helsinki, Finland
    Plant Physiol 161:744-59. 2013
    ..Moreover, UVR8-dependent UV-B acclimation during the early stages of plant development may enhance normal growth under long-term exposure to solar UV...
  14. doi request reprint Regulation of ABA dependent wound induced spreading cell death by MYB108
    Fuqiang Cui
    College of Biological Sciences, China Agricultural University, Beijing, 100193, China Division of Plant Biology, Department of Biosciences, University of Helsinki, FI 00014, Helsinki, Finland
    New Phytol 200:634-40. 2013
    ..This program is distinct from other known cell death programs in that it is ABA dependent, but independent of salicylate biosynthesis, ethylene, jasmonate, metacaspases and ROS derived from RBOHD and RBOHF. ..
  15. doi request reprint The Arabidopsis thaliana cysteine-rich receptor-like kinases CRK6 and CRK7 protect against apoplastic oxidative stress
    Niina Idänheimo
    Division of Plant Biology, Department of Biosciences, University of Helsinki, FI 00014 Helsinki, Finland Electronic address
    Biochem Biophys Res Commun 445:457-62. 2014
    ..CRK6 and CRK7 are active protein kinases with differential preference for divalent cations. Our results suggest that CRK7 is involved in mediating the responses to extracellular but not chloroplastic ROS production. ..
  16. ncbi request reprint Stress hormone-independent activation and nuclear translocation of mitogen-activated protein kinases in Arabidopsis thaliana during ozone exposure
    Reetta Ahlfors
    Plant Biology, Department of Biological and Environmental Sciences, University of Helsinki, PO Box 56 Viikinkaari 9, FI 00014 Helsinki, Finland
    Plant J 40:512-22. 2004
    ..The use of O3 to induce apoplastic ROS formation offers a non-invasive in planta system amenable to reverse genetics that can be used for the study of stress-responsive MAPK signaling in plants...
  17. pmc Arabidopsis GRI is involved in the regulation of cell death induced by extracellular ROS
    Michael Wrzaczek
    Plant Biology, Department of Biological and Environmental Sciences, University of Helsinki, P O B 65, FI 00014 Helsinki, Finland
    Proc Natl Acad Sci U S A 106:5412-7. 2009
    ..Analysis of the extracellular GRI protein yields information on how plants can initiate ROS-induced cell death during stress response and development...
  18. pmc SLAC1 is required for plant guard cell S-type anion channel function in stomatal signalling
    Triin Vahisalu
    Plant Biology, Department of Biological and Environmental Sciences, University of Helsinki, FI 00014 Helsinki, Finland
    Nature 452:487-91. 2008
    ..A low homology of SLAC1 to bacterial and fungal organic acid transport proteins, and the permeability of S-type anion channels to malate suggest a vital role for SLAC1 in the function of S-type anion channels...
  19. doi request reprint Temporal variation in epidermal flavonoids due to altered solar UV radiation is moderated by the leaf position in Betula pendula
    Luis O Morales
    Department of Biosciences, Plant Biology, University of Helsinki, P O Box 65, FIN 00014 Helsinki, Finland
    Physiol Plant 143:261-70. 2011
    ..Silver birch leaves modulate their protective pigments in response to changes in the UV environment during their expansion, and their previous UV exposure history affects the epidermal-absorbance achieved during later UV exposure...
  20. doi request reprint Are solar UV-B- and UV-A-dependent gene expression and metabolite accumulation in Arabidopsis mediated by the stress response regulator RADICAL-INDUCED CELL DEATH1?
    Luis O Morales
    Division of Plant Biology, Department of Biosciences, University of Helsinki, FI 00014, Helsinki, Finland School of Chemical Technology, Department of Forest Products Technology, Aalto University, FI 00076, Aalto, Finland
    Plant Cell Environ 38:878-91. 2015
    ..We conclude that RCD1 does not play an active role in UV-B signalling but rather modulates UV-B responses under full spectrum sunlight. ..
  21. pmc Transcriptomics and functional genomics of ROS-induced cell death regulation by RADICAL-INDUCED CELL DEATH1
    Mikael Brosché
    Division of Plant Biology, Department of Biosciences, University of Helsinki, Helsinki, Finland Institute of Technology, University of Tartu, Tartu, Estonia
    PLoS Genet 10:e1004112. 2014
    ..Using a rcd1 double mutant collection we show that SIMR is mostly independent of the classical plant defense signaling pathways and that the redox balance is involved in development of SIMR. ..
  22. doi request reprint Natural variation in ozone sensitivity among Arabidopsis thaliana accessions and its relation to stomatal conductance
    Mikael Brosché
    Division of Plant Biology, Department of Biosciences, University of Helsinki, FI 00014 Helsinki, Finland
    Plant Cell Environ 33:914-25. 2010
    ..The major O(3) QTL mapped to the same position as the water loss QTL further supporting the role of stomata in regulating O(3) entry and damage...
  23. doi request reprint ROS signaling loops - production, perception, regulation
    Michael Wrzaczek
    Division of Plant Biology, Department of Biosciences, University of Helsinki, FI 00014 Helsinki, Finland
    Curr Opin Plant Biol 16:575-82. 2013
    ..Direct redox modification of transcription factors and other proteins are critical for the perception of intracellular reactive oxygen species; however, sensing of their extracellular counterparts awaits elucidation. ..
  24. pmc The transcription factor interacting protein RCD1 contains a novel conserved domain
    Pinja Jaspers
    Plant Biology, Department of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland
    Plant Signal Behav 5:78-80. 2010
    ..Here we summarize recent findings on the protein-protein interactions mediated by RCD1 and highlight the different functional possibilities that form the basis of our future experiments concerning the biochemical function of RCD1...
  25. pmc Arabidopsis RADICAL-INDUCED CELL DEATH1 belongs to the WWE protein-protein interaction domain protein family and modulates abscisic acid, ethylene, and methyl jasmonate responses
    Reetta Ahlfors
    Department of Biological and Environmental Sciences, Viikki Biocenter, University of Helsinki, 00014, Finland
    Plant Cell 16:1925-37. 2004
    ..The results suggest that RCD1 could act as an integrative node in hormonal signaling and in the regulation of several stress-responsive genes...
  26. doi request reprint Dissecting Abscisic Acid Signaling Pathways Involved in Cuticle Formation
    Fuqiang Cui
    Division of Plant Biology, Viikki Plant Science Centre, Department of Biosciences, University of Helsinki, 00014 Helsinki, Finland Electronic address
    Mol Plant 9:926-38. 2016
    ..These results define a cuticle-specific downstream branch in the ABA signaling pathway that regulates responses to the external environment. ..
  27. pmc Specificity in ROS signaling and transcript signatures
    Lauri Vaahtera
    1 Division of Plant Biology, Department of Biosciences, University of Helsinki, Helsinki, Finland
    Antioxid Redox Signal 21:1422-41. 2014
    ..ROS production can trigger broad transcriptional changes; however, it is not clear how specificity in transcriptional regulation is achieved...
  28. doi request reprint Effects of solar UV-A and UV-B radiation on gene expression and phenolic accumulation in Betula pendula leaves
    Luis O Morales
    Department of Biosciences, Division of Plant Biology, PO Box 65 Biocenter 3, Viikinkaari 1, FIN 00014, University of Helsinki, Helsinki, Finland
    Tree Physiol 30:923-34. 2010
    ..Our findings in silver birch contribute to a more detailed understanding of plant responses to solar UV radiation at both molecular and metabolite levels...
  29. doi request reprint Quantitative trait loci mapping and transcriptome analysis reveal candidate genes regulating the response to ozone in Arabidopsis thaliana
    Enjun Xu
    Division of Plant Biology, Department of Biosciences, University of Helsinki, Helsinki, FI 00014, Finland
    Plant Cell Environ 38:1418-33. 2015
    ..Application of exogenous SA prior to O3 exposure can mimic the constitutive SA signalling in C24 and could attenuate O3 -induced leaf damage in the sensitive Arabidopsis accessions Te and Cvi-0. ..
  30. doi request reprint Roles of Defense Hormones in the Regulation of Ozone-Induced Changes in Gene Expression and Cell Death
    Enjun Xu
    Division of Plant Biology, Department of Biosciences, Viikki Plant Science Centre, University of Helsinki, PO Box 65 Viikinkaari 1, 00014 Helsinki, Finland
    Mol Plant 8:1776-94. 2015
    ..In response to apoplastic ROS, there is not a single signaling pathway that regulates gene expression or cell death. Instead, several pathways regulate the apoplastic ROS response via combinatorial or overlapping mechanisms...
  31. doi request reprint To open or to close: species-specific stomatal responses to simultaneously applied opposing environmental factors
    Ebe Merilo
    Institute of Technology, University of Tartu, Nooruse 1, 50411, Tartu, Estonia
    New Phytol 202:499-508. 2014
    ..Our results, indicating that in changing environmental conditions species-specific stomatal responses are evident that cannot be predicted from studying one factor at a time, might be interesting for stomatal modellers, too. ..
  32. pmc Ozone and nitric oxide interaction in Arabidopsis thaliana: a role for ethylene?
    Reetta Ahlfors
    Plant Biology, Department of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland
    Plant Signal Behav 4:878-9. 2009
    ..In addition, NO can elevate the levels of ethylene in several mutants. Thus, NO is a modifier of ROS signaling...
  33. doi request reprint More than the sum of its parts--how to achieve a specific transcriptional response to abiotic stress
    Lauri Vaahtera
    Division of Plant Biology, Department of Biosciences, University of Helsinki, P O Box 65, Viikinkaari 1, FI 00014 Helsinki, Finland
    Plant Sci 180:421-30. 2011
    ..In this review recent progress in abiotic stress signalling is discussed with emphasis on possible mechanisms for generating specific responses...
  34. pmc A genetic framework for H2O2 induced cell death in Arabidopsis thaliana
    Eve Kaurilind
    Division of Plant Biology, Department of Biosciences, Viikki Plant Science Centre, University of Helsinki, Helsinki, Finland
    BMC Genomics 16:837. 2015
    ..The Arabidopsis thaliana catalase2 (cat2) mutant lacks a peroxisomal catalase and under photorespiratory conditions accumulates H2O2, which leads to activation of cell death...