Ahmet Civas

Summary

Country: France

Publications

  1. ncbi Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKepsilon
    Ahmet Civas
    UPR 2228 CNRS, Laboratoire de Régulation Transcriptionnelle et Maladies Génétiques, UFR Biomédicale des Saints Pères, Universite Paris V, 45 Rue des Saints Peres, 75270 Paris Cedex 06, France
    J Biol Chem 281:4856-66. 2006
  2. ncbi Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription
    Pierre Morin
    UPR 2228 CNRS, Laboratoire de Régulation Transcriptionnelle et Maladies Génétiques, UFR Biomédicale des Saints Pères, Universite Paris V, 45 Rue des Saints Peres, 75270 Paris Cedex 06, France
    J Mol Biol 316:1009-22. 2002
  3. ncbi Positive and negative control of virus-induced interferon-A gene expression
    Thibault Mesplede
    UPR 2228 CNRS, Laboratoire de Régulation Transcriptionnelle et Maladies Génétiques, UFR Biomédicale des Saints Pères, Universite Paris V, 45, rue des Saints Pères, 75270 Paris Cedex 06, France
    Autoimmunity 36:447-55. 2003
  4. pmc Impairment of interferon-induced IRF-7 gene expression due to inhibition of ISGF3 formation by trichostatin A
    Pierre Genin
    UPR 2228 CNRS, Laboratoire de Régulation Transcriptionnelle et Maladies Génétiques, UFR Biomédicale des Saints Pères, Universite Paris V, 75270 Paris Cedex 06, France
    J Virol 77:7113-9. 2003
  5. pmc Differential regulation of human interferon A gene expression by interferon regulatory factors 3 and 7
    Pierre Genin
    UPR 2228 CNRS, Laboratoire de Régulation Transcriptionnelle et Maladies Génétiques, UFR Biomédicale des Saints Pères, Universite Paris Descartes, 45 Rue des Saints Peres, 75270 Paris Cedex 06, France
    Mol Cell Biol 29:3435-50. 2009
  6. ncbi Regulation of virus-induced interferon-A genes
    Ahmet Civas
    UPR 2228, CNRS, Laboratoire de Régulation Transcriptionnelle et Maladies Génétiques, UFR Biomédicale des Saints Pères, Universite Paris V, 45, rue des Saints Pères, 75270 Paris Cedex 6, France
    Biochimie 84:643-54. 2002
  7. ncbi The virus-induced factor VIF differentially recognizes the virus-responsive modules of the mouse IFNA4 gene promoter
    Pierre Morin
    UPR 2228 CNRS, Régulation Transcriptionnelle et Maladies Génétiques, UFR Biomédicale des Saints Pères, Universite Paris V, 75270 Paris Cedex 06, France
    J Interferon Cytokine Res 22:77-86. 2002
  8. doi The role of differential expression of human interferon--a genes in antiviral immunity
    Pierre Genin
    Universite Paris Descartes, UPR 2228 CNRS Laboratoire de Régulation Transcriptionnelle et Maladies Génétiques UFR Biomédicale des Saints Pères, 45 Rue des Saints Peres, 75270 Paris Cedex 06, France
    Cytokine Growth Factor Rev 20:283-95. 2009
  9. ncbi Distinct functions of IRF-3 and IRF-7 in IFN-alpha gene regulation and control of anti-tumor activity in primary macrophages
    Mayra Solis
    Terry Fox Molecular Oncology Group, Lady Davis Institute for Medical Research, McGill University, Montreal, Canada H3T 1E2
    Biochem Pharmacol 72:1469-76. 2006

Collaborators

  • Rongtuan Lin
  • J Hiscott
  • Pierre Genin
  • Pierre Morin
  • Mayra Solis
  • Thibault Mesplede
  • Janine Doly
  • Alexandra Vaccaro
  • Delphine Goubau
  • Raphaelle Romieu-Mourez
  • Marie Laure Island
  • Sébastien Navarro
  • Eliette Bonnefoy
  • Marie Thérèse Bandu
  • Jose Braganca

Detail Information

Publications9

  1. ncbi Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKepsilon
    Ahmet Civas
    UPR 2228 CNRS, Laboratoire de Régulation Transcriptionnelle et Maladies Génétiques, UFR Biomédicale des Saints Pères, Universite Paris V, 45 Rue des Saints Peres, 75270 Paris Cedex 06, France
    J Biol Chem 281:4856-66. 2006
    ....
  2. ncbi Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription
    Pierre Morin
    UPR 2228 CNRS, Laboratoire de Régulation Transcriptionnelle et Maladies Génétiques, UFR Biomédicale des Saints Pères, Universite Paris V, 45 Rue des Saints Peres, 75270 Paris Cedex 06, France
    J Mol Biol 316:1009-22. 2002
    ....
  3. ncbi Positive and negative control of virus-induced interferon-A gene expression
    Thibault Mesplede
    UPR 2228 CNRS, Laboratoire de Régulation Transcriptionnelle et Maladies Génétiques, UFR Biomédicale des Saints Pères, Universite Paris V, 45, rue des Saints Pères, 75270 Paris Cedex 06, France
    Autoimmunity 36:447-55. 2003
    ....
  4. pmc Impairment of interferon-induced IRF-7 gene expression due to inhibition of ISGF3 formation by trichostatin A
    Pierre Genin
    UPR 2228 CNRS, Laboratoire de Régulation Transcriptionnelle et Maladies Génétiques, UFR Biomédicale des Saints Pères, Universite Paris V, 75270 Paris Cedex 06, France
    J Virol 77:7113-9. 2003
    ..Our data suggest that an acetylation/deacetylation mechanism participates in the regulation of cellular distribution and function of STAT2 in IFN-alpha/beta signaling...
  5. pmc Differential regulation of human interferon A gene expression by interferon regulatory factors 3 and 7
    Pierre Genin
    UPR 2228 CNRS, Laboratoire de Régulation Transcriptionnelle et Maladies Génétiques, UFR Biomédicale des Saints Pères, Universite Paris Descartes, 45 Rue des Saints Peres, 75270 Paris Cedex 06, France
    Mol Cell Biol 29:3435-50. 2009
    ..This regulatory mechanism contributes to differential expression of IFN-A genes and may be critical for alpha interferon production in different cell types by RIG-I-dependent signals, leading to innate antiviral immune responses...
  6. ncbi Regulation of virus-induced interferon-A genes
    Ahmet Civas
    UPR 2228, CNRS, Laboratoire de Régulation Transcriptionnelle et Maladies Génétiques, UFR Biomédicale des Saints Pères, Universite Paris V, 45, rue des Saints Pères, 75270 Paris Cedex 6, France
    Biochimie 84:643-54. 2002
    ....
  7. ncbi The virus-induced factor VIF differentially recognizes the virus-responsive modules of the mouse IFNA4 gene promoter
    Pierre Morin
    UPR 2228 CNRS, Régulation Transcriptionnelle et Maladies Génétiques, UFR Biomédicale des Saints Pères, Universite Paris V, 75270 Paris Cedex 06, France
    J Interferon Cytokine Res 22:77-86. 2002
    ..These results indicate that VIF differentially recognizes the virus-responsive modules of VRE-A4 and further actualize our previous model concerning the differential expression of murine IFNA genes...
  8. doi The role of differential expression of human interferon--a genes in antiviral immunity
    Pierre Genin
    Universite Paris Descartes, UPR 2228 CNRS Laboratoire de Régulation Transcriptionnelle et Maladies Génétiques UFR Biomédicale des Saints Pères, 45 Rue des Saints Peres, 75270 Paris Cedex 06, France
    Cytokine Growth Factor Rev 20:283-95. 2009
    ..Taken together, this information enhances our understanding of the selective advantage of the multiplicity of IFN-alpha subtypes in the regulation of innate and adaptive immunity...
  9. ncbi Distinct functions of IRF-3 and IRF-7 in IFN-alpha gene regulation and control of anti-tumor activity in primary macrophages
    Mayra Solis
    Terry Fox Molecular Oncology Group, Lady Davis Institute for Medical Research, McGill University, Montreal, Canada H3T 1E2
    Biochem Pharmacol 72:1469-76. 2006
    ..These studies indicate that IRF-7 transduced macrophages may be an attractive candidate for in vivo adoptive therapy of cancer...