F Gondret

Summary

Affiliation: Institut National de la Recherche Agronomique
Country: France

Publications

  1. pmc Molecular alterations induced by a high-fat high-fiber diet in porcine adipose tissues: variations according to the anatomical fat location
    Florence Gondret
    INRA, UMR1348 PEGASE, F 35590, Saint Gilles, France
    BMC Genomics 17:120. 2016
  2. doi request reprint Dietary energy sources affect the partition of body lipids and the hierarchy of energy metabolic pathways in growing pigs differing in feed efficiency
    F Gondret
    INRA, UMR1348 PEGASE, F 35590 Saint Gilles, France AGROCAMPUS OUEST, UMR1348 PEGASE, F 35000 Rennes, France
    J Anim Sci 92:4865-77. 2014
  3. pmc Using a large-scale knowledge database on reactions and regulations to propose key upstream regulators of various sets of molecules participating in cell metabolism
    Pierre Blavy
    CNRS Université de Rennes 1 INRIA, UMR6074 IRISA, Campus de Beaulieu, 35042 Rennes, Cedex, France
    BMC Syst Biol 8:32. 2014
  4. pmc Unusual metabolic characteristics in skeletal muscles of transgenic rabbits for human lipoprotein lipase
    Florence Gondret
    INRA, UMR sur le Veau et le Porc, 35590 Saint Gilles, France
    Lipids Health Dis 3:27. 2004
  5. doi request reprint Spontaneous intra-uterine growth restriction modulates the endocrine status and the developmental expression of genes in porcine fetal and neonatal adipose tissue
    Florence Gondret
    INRA, UMR1348 PEGASE, F 35590 Saint Gilles, France AgrocampusOuest, UMR1348 PEGASE, F 35000 Rennes, France Electronic address
    Gen Comp Endocrinol 194:208-16. 2013
  6. doi request reprint Towards candidate genes affecting body fatness at the SSC7 QTL by expression analyses
    F Gondret
    INRA, UMR1079 Systèmes d Elevage, Nutrition Animale et Humaine, Domaine de la Prise, Saint Gilles, France
    J Anim Breed Genet 129:316-24. 2012
  7. doi request reprint A comparison of subcutaneous adipose tissue proteomes in juvenile piglets with a contrasted adiposity underscored similarities with human obesity
    Florence Gondret
    INRA, UMR1079 Systèmes d Elevage, Nutrition Animale et Humaine, Domaine de la Prise, 35590 Saint Gilles, France
    J Proteomics 75:949-61. 2012
  8. doi request reprint Skeletal muscle adaptations and biomechanical properties of tendons in response to jump exercise in rabbits
    F Gondret
    Institut National de Recherche Agronomique, Unité Mixte de Recherche 1079 Systèmes d Elevage Nutrition Animale et Humaine, 35590 Saint Gilles, France
    J Anim Sci 87:544-53. 2009
  9. doi request reprint Regional differences in porcine adipocytes isolated from skeletal muscle and adipose tissues as identified by a proteomic approach
    F Gondret
    Institut National de la Recherche Agronomique INRA, Unité Mixte de Recherches UMR 1079 Systèmes d Elevage Nutrition Animale et Humaine, Saint Gilles, 35590, France
    J Anim Sci 86:2115-25. 2008
  10. ncbi request reprint Does feed restriction and re-alimentation differently affect lipid content and metabolism according to muscle type in pigs (Sus scrofa)?
    Florence Gondret
    INRA, UMR 1079 Systemes d Elevage, Nutrition Animale et Humaine SENAH, Domaine de la Prise, 35590 Saint Gilles, France
    Comp Biochem Physiol A Mol Integr Physiol 147:375-82. 2007

Detail Information

Publications40

  1. pmc Molecular alterations induced by a high-fat high-fiber diet in porcine adipose tissues: variations according to the anatomical fat location
    Florence Gondret
    INRA, UMR1348 PEGASE, F 35590, Saint Gilles, France
    BMC Genomics 17:120. 2016
    ....
  2. doi request reprint Dietary energy sources affect the partition of body lipids and the hierarchy of energy metabolic pathways in growing pigs differing in feed efficiency
    F Gondret
    INRA, UMR1348 PEGASE, F 35590 Saint Gilles, France AGROCAMPUS OUEST, UMR1348 PEGASE, F 35000 Rennes, France
    J Anim Sci 92:4865-77. 2014
    ....
  3. pmc Using a large-scale knowledge database on reactions and regulations to propose key upstream regulators of various sets of molecules participating in cell metabolism
    Pierre Blavy
    CNRS Université de Rennes 1 INRIA, UMR6074 IRISA, Campus de Beaulieu, 35042 Rennes, Cedex, France
    BMC Syst Biol 8:32. 2014
    ..This study aimed at developing an automatic method to propose a reasonable number of upstream regulatory candidates from lists of various regulated molecules by confronting experimental data with encyclopedic information...
  4. pmc Unusual metabolic characteristics in skeletal muscles of transgenic rabbits for human lipoprotein lipase
    Florence Gondret
    INRA, UMR sur le Veau et le Porc, 35590 Saint Gilles, France
    Lipids Health Dis 3:27. 2004
    ....
  5. doi request reprint Spontaneous intra-uterine growth restriction modulates the endocrine status and the developmental expression of genes in porcine fetal and neonatal adipose tissue
    Florence Gondret
    INRA, UMR1348 PEGASE, F 35590 Saint Gilles, France AgrocampusOuest, UMR1348 PEGASE, F 35000 Rennes, France Electronic address
    Gen Comp Endocrinol 194:208-16. 2013
    ..The data indicate that IUGR delays the normal ontogeny of adipose tissue across gestation and affects the insulin and IGF axes around birth...
  6. doi request reprint Towards candidate genes affecting body fatness at the SSC7 QTL by expression analyses
    F Gondret
    INRA, UMR1079 Systèmes d Elevage, Nutrition Animale et Humaine, Domaine de la Prise, Saint Gilles, France
    J Anim Breed Genet 129:316-24. 2012
    ..These results re-evaluate the potential of PPARD to explain part of variation in pig adiposity...
  7. doi request reprint A comparison of subcutaneous adipose tissue proteomes in juvenile piglets with a contrasted adiposity underscored similarities with human obesity
    Florence Gondret
    INRA, UMR1079 Systèmes d Elevage, Nutrition Animale et Humaine, Domaine de la Prise, 35590 Saint Gilles, France
    J Proteomics 75:949-61. 2012
    ..Our results are relevant in the context of data linking the accretion of body lipids to the physiology and pathology of adipose tissue in models other than rodents for a better control of human health and nutrition...
  8. doi request reprint Skeletal muscle adaptations and biomechanical properties of tendons in response to jump exercise in rabbits
    F Gondret
    Institut National de Recherche Agronomique, Unité Mixte de Recherche 1079 Systèmes d Elevage Nutrition Animale et Humaine, 35590 Saint Gilles, France
    J Anim Sci 87:544-53. 2009
    ..This experiment demonstrates that rabbit muscles turn to a more oxidative metabolic pattern in response to jump exercise. The quality of attachment of cooked meat to bone is also improved in active rabbits...
  9. doi request reprint Regional differences in porcine adipocytes isolated from skeletal muscle and adipose tissues as identified by a proteomic approach
    F Gondret
    Institut National de la Recherche Agronomique INRA, Unité Mixte de Recherches UMR 1079 Systèmes d Elevage Nutrition Animale et Humaine, Saint Gilles, 35590, France
    J Anim Sci 86:2115-25. 2008
    ..m. adipocytes is low. Thus, triggering adipogenesis rather than cell metabolism per se might be a valuable strategy to control lipid deposition in pig skeletal muscles...
  10. ncbi request reprint Does feed restriction and re-alimentation differently affect lipid content and metabolism according to muscle type in pigs (Sus scrofa)?
    Florence Gondret
    INRA, UMR 1079 Systemes d Elevage, Nutrition Animale et Humaine SENAH, Domaine de la Prise, 35590 Saint Gilles, France
    Comp Biochem Physiol A Mol Integr Physiol 147:375-82. 2007
    ..In conclusion, metabolic activities in response to restriction and re-feeding differed according to muscle metabolic type...
  11. ncbi request reprint Effects of exercise during growth and alternative rearing systems on muscle fibers and collagen properties
    Florence Gondret
    INRA, Unité Mixte de Recherches sur le Veau et le Porc, 35590 Saint Gilles, France
    Reprod Nutr Dev 45:69-86. 2005
    ..Therefore, exercise studies are unsuitable to predict adaptative responses in muscle characteristics to alternative outdoor rearing systems, and in fine meat quality...
  12. ncbi request reprint Carcass composition, bone mechanical properties, and meat quality traits in relation to growth rate in rabbits
    F Gondret
    Institut National de la Recherche Agronomique, Unité Mixte de Recherche sur les Systèmes d Elevage, Nutrition Animale et Humaine SENAH, 35590 Saint Gilles, France
    J Anim Sci 83:1526-35. 2005
    ..001) in LM (n = 128) from HIGH rabbits. Results from this study indicate that improvement of growth rate by selection has little effect in rabbit carcass and meat quality traits...
  13. ncbi request reprint Low birth weight is associated with enlarged muscle fiber area and impaired meat tenderness of the longissimus muscle in pigs
    F Gondret
    Institut National de la Recherche Agronomique, Unité Mixte de Recherches Systèmes d Elevage, Nutrition Animale et Humaine, F 35590 Saint Gilles, France
    J Anim Sci 84:93-103. 2006
    ..06) and between LM tenderness and mean cross-sectional area of myofibers (r = -0.34; P = 0.07). This study demonstrates a lower tenderness of meat from pigs that had a LW, partly as a result of their enlarged myofibers at market weight...
  14. ncbi request reprint Number of intramuscular adipocytes and fatty acid binding protein-4 content are significant indicators of intramuscular fat level in crossbred Large White x Duroc pigs
    M Damon
    Unité Mixte de Recherches Systèmes d Elevage Nutrition Animale et Humaine, Institut National de la Recherche Agronomique, 35590 Saint Gilles, France
    J Anim Sci 84:1083-92. 2006
    ..49). The current study suggests that FABP-4 protein content may be a valuable marker of lipid accretion in LM and that i.m. fat content and myofiber type composition can be manipulated independently...
  15. doi request reprint Prenatal exposure to maternal low or high protein diets induces modest changes in the adipose tissue proteome of newborn piglets
    O Sarr
    INRA, UMR1079 Systèmes d Elevage Nutrition Animale et Humaine, F 35590 Saint Gilles, France
    J Anim Sci 88:1626-41. 2010
    ..In conclusion, the proteomics tool has allowed the identification of early changes in various molecular pathways of SCAT in response to the levels of maternal protein supply during gestation...
  16. ncbi request reprint Feeding intensity and dietary protein level affect adipocyte cellularity and lipogenic capacity of muscle homogenates in growing pigs, without modification of the expression of sterol regulatory element binding protein
    F Gondret
    Institut National de la Recherche Agronomique, Unité Mixte de Recherches sur le Veau et le Porc, 35590 Saint Gilles, France
    J Anim Sci 80:3184-93. 2002
    ..In contrast, the reduction of both protein and energy intakes more likely results in an imbalance between multiple aspects of muscle energy metabolism, in favor of intramuscular fat accretion...
  17. doi request reprint Metabolic changes and tissue responses to selection on residual feed intake in growing pigs
    T Le Naou
    INRA, UMR1348 PEGASE, F 35590 Saint Gilles, France
    J Anim Sci 90:4771-80. 2012
    ..In conclusion, the present study shows an increase of catabolic pathway activities in the liver and muscle of RFI(+) pigs at market weight that is likely to generate more ATP compared with RFI(-) pigs...
  18. ncbi request reprint GH and insulin affect fatty acid synthase activity in isolated porcine adipocytes in culture without any modifications of sterol regulatory element binding protein-1 expression
    I Louveau
    Institut National de la Recherche Agronomique, Unité Mixte de Recherches sur le Veau et le Porc, 35590 Saint Gilles, France
    J Endocrinol 181:271-80. 2004
    ..Taken together, these data indicate that the regulation of lipogenesis by insulin and GH appears to not involve changes in SREBP-1 mRNA levels in porcine adipocytes...
  19. ncbi request reprint Regulation of development and metabolism of adipose tissue by growth hormone and the insulin-like growth factor system
    I Louveau
    Institut National de la Recherche Agronomique, Unité Mixte de Recherches sur le Veau et le Porc, 35590 Saint Gilles, France
    Domest Anim Endocrinol 27:241-55. 2004
    ..GH is apparently the main regulator of IGF-I mRNA expression in adipose tissue, however, the effects of IGF-I on this tissue are rather unclear...
  20. doi request reprint Differential gene expressions in subcutaneous adipose tissue pointed to a delayed adipocytic differentiation in small pig fetuses compared to their heavier siblings
    F Gondret
    INRA, UMR1079 Systèmes d Elevage, Nutrition Animale et Humaine SENAH, F 35590 Saint Gilles, France AGROCAMPUS OUEST, UMR1079 SENAH, 65 rue de St Brieuc, F 35000 Rennes, France
    Differentiation 81:253-60. 2011
    ..The gene expression changes observed in the smallest fetuses are likely associated to a lower body fat content at birth, and could predispose to catch-up fat growth during the postnatal period...
  21. ncbi request reprint Effects of simultaneous gestation and lactation in rabbit does on muscular characteristics of the youngs
    F Gondret
    Station de Recherches Cunicoles, INRA, Castanet Tolosan, France
    Reprod Nutr Dev 37:163-72. 1997
    ..On day 70, the proportion of the MHC isoforms was similar in the two groups. These results suggest that concurrent gestation and lactation delayed the myofibrillar maturation rate...
  22. ncbi request reprint Cellular and biochemical features of skeletal muscle in obese Yucatan minipigs
    Christelle Guillerm-Regost
    Institut National de la Recherche Agronomique Agrocampus Rennes, Unite Mixte de Recherche, Livestock Production Systems, Animal and Human Nutrition, Saint Gilles, France
    Obesity (Silver Spring) 14:1700-7. 2006
    ..To examine cellular and biochemical features of skeletal muscle in response to dietary-induced obesity in a novel Yucatan minipig model of childhood obesity...
  23. ncbi request reprint Adipocyte- and heart-type fatty acid binding proteins are both expressed in subcutaneous and intramuscular porcine (Sus scrofa) adipocytes
    Delphine Gardan
    INRA, UMR1079 Systèmes d Elevage Nutrition Animale et Humaine, Saint Gilles, France
    Comp Biochem Physiol B Biochem Mol Biol 148:14-9. 2007
    ..A discrepancy was observed between age-related changes in A-FABP content in isolated adipocytes and cell diameter or lipid content variations in tissues during growth...
  24. doi request reprint Review: divergent selection for residual feed intake in the growing pig
    H Gilbert
    1GenPhySE, INRA, INP, ENSAT, Universite de Toulouse, 31326 Castanet Tolosan, France
    Animal . 2017
    ....
  25. doi request reprint A minimal model for hepatic fatty acid balance during fasting: application to PPAR alpha-deficient mice
    P Blavy
    INRA, UMR 1079 Systemes d Elevage, Nutrition Animale et Humaine, F 35590 Saint Gilles, France
    J Theor Biol 261:266-78. 2009
    ..These results confirm that mathematical models can be a useful tool in identifying new biological hypotheses and nutritional routes in metabolism...
  26. doi request reprint Meal frequency changes the basal and time-course profiles of plasma nutrient concentrations and affects feed efficiency in young growing pigs
    T Le Naou
    INRA, UMR1348 PEGASE, Saint Gilles, France
    J Anim Sci 92:2008-16. 2014
    ..001) in M2 pigs than in M12 pigs. Altogether, the less frequent daily meal intake improves the conversion of feed into weight gain, without marked modifications of tissue composition in young pigs. ..
  27. ncbi request reprint ADD-1/SREBP-1 is a major determinant of tissue differential lipogenic capacity in mammalian and avian species
    F Gondret
    INSERM Unité 465, Institut Biomedical des Cordeliers, 75006 Paris, France
    J Lipid Res 42:106-13. 2001
    ..Gondret, F., P. Ferré, and I. Dugail. ADD-1/SREBP-1 is a major determinant of tissue differential lipogenic capacity in mammalian and avian species. J. Lipid Res. 2001. 42: 106;-113...
  28. doi request reprint Differentially-expressed genes in pig Longissimus muscles with contrasting levels of fat, as identified by combined transcriptomic, reverse transcription PCR, and proteomic analyses
    Jingshun Liu
    INRA, UMR1079 Systèmes d Elevage Nutrition Animale et Humaine, 35590 Saint Gilles, France
    J Agric Food Chem 57:3808-17. 2009
    ..These results suggest that interindividual variability in intramuscular fat content might arise essentially from differences in early adipogenesis...
  29. ncbi request reprint Metabolic and histochemical characteristics of fat and muscle tissues in homozygous or heterozygous pigs for the body composition QTL located on chromosome 7
    Julie Demars
    Institut National de la Recherche Agronomique, Unité Mixte de Recherche 444, Laboratoire de Genetique Cellulaire, BP52627, Castanet Tolosan, France
    Physiol Genomics 30:232-41. 2007
    ..Some candidate genes known for their functions on adipocyte growth and differentiation are suggested...
  30. pmc Divergent selection on 63-day body weight in the rabbit: response on growth, carcass and muscle traits
    Catherine Larzul
    Station d Amélioration Génétique des Animaux, Institut National de la Recherche Agronomique, BP 27, 31326 Castanet Tolosan, France
    Genet Sel Evol 37:105-22. 2005
    ..In the Longissimus muscle (N = 180), the ultimate pH (h2 = 0.16) and the maximum shear force reached in the Warner-Braztler test (h2 = 0.57) were slightly modified by selection...
  31. ncbi request reprint Age-related changes in glucose utilization and fatty acid oxidation in a muscle-specific manner during rabbit growth
    Florence Gondret
    INRA, Unité Mixte de Recherches sur le Veau et le Porc, Saint Gilles, France
    J Muscle Res Cell Motil 25:405-10. 2004
    ..In conclusion, mitochondrial oxidation rate of fatty acids and activities of selected mitochondrial enzymes were largely unrelated. Moreover, regulation of energy metabolism with advancing age differed between muscle types...
  32. ncbi request reprint Age-related relationships between muscle fat content and metabolic traits in growing rabbits
    Florence Gondret
    INRA, Unité Mixte de Recherches sur le Veau et le Porc, 35590 Saint Gilles, France
    Reprod Nutr Dev 44:1-16. 2004
    ..15, P = 0.07). In growing rabbits, muscle fat content variation was proven to result from a reciprocal balance between catabolic and anabolic fatty acid fluxes, rather than to be assigned to one specific energy metabolic pathway...
  33. doi request reprint Delayed muscle development in small pig fetuses around birth cannot be rectified by maternal early feed restriction and subsequent overfeeding during gestation
    M H Perruchot
    1INRA, UMR1348 PEGASE, F 35590 Saint Gilles, France
    Animal 9:1996-2005. 2015
    ..Altogether, intrauterine growth restriction impaired fetal muscle development, and restricted feeding followed by overfeeding of gestating sows did not allow small fetuses to recover normal contractile and metabolic characteristics. ..
  34. ncbi request reprint Invited review: Pre- and postnatal adipose tissue development in farm animals: from stem cells to adipocyte physiology
    I Louveau
    1INRA, UMR1348 PEGASE, F 35590 Saint Gilles, France
    Animal 10:1839-1847. 2016
    ..Altogether, a better knowledge of fetal and postnatal adipose tissue development is important for various aspects of animal production, including neonatal survival, postnatal growth efficiency and health...
  35. doi request reprint Production performance, carcass composition, and adipose tissue traits of heavy pigs: influence of breed and production system
    B Lebret
    INRA, UMR1348 PEGASE, F 35590 Saint Gilles, France AGROCAMPUS OUEST, UMR1348 PEGASE, F 35000 Rennes, France
    J Anim Sci 92:3543-56. 2014
    ..015) SFA and greater (P < 0.001) PUFA in SCAT of the B pigs. Altogether, the E production system can counteract the genetic potential of B pigs for growth rate but also body fatness. ..
  36. doi request reprint Difference in short-term responses to a high-fiber diet in pigs divergently selected for residual feed intake
    L Montagne
    INRA, UMR1348 PEGASE, F 35590 Saint Gilles, France
    J Anim Sci 92:1512-23. 2014
    ..In conclusion, the low RFI pigs seem to better utilize a high-fiber diet than high RFI pigs. This was not associated with marked changes in digestion, and the underlying metabolic mechanisms remain to be clarified. ..
  37. doi request reprint Pertinent plasma indicators of the ability of chickens to synthesize and store lipids
    E Baeza
    INRA, UR83 Recherches Avicoles, F 37380 Nouzilly, France
    J Anim Sci 93:107-16. 2015
    ....
  38. ncbi request reprint Lipid metabolism and cellular features of skeletal muscle and subcutaneous adipose tissue in pigs differing in IGF-II genotype
    Delphine Gardan
    INRA, Unite Mixte de Recherches, Systèmes d Elevage, Nutrition Animale et Humaine, 35590 Saint Gilles, France
    Domest Anim Endocrinol 34:45-53. 2008
    ..In summary, our results suggest that the IGF-II mutation altered body composition in pigs by favoring myofiber hypertrophy and repressing adipose cell development in SCAT...
  39. ncbi request reprint Lipid metabolism and secretory function of porcine intramuscular adipocytes compared with subcutaneous and perirenal adipocytes
    Delphine Gardan
    Institut National de la Recherche Agronomique Agrocampus Rennes, Unite Mixte de Recherches, France
    Am J Physiol Endocrinol Metab 291:E372-80. 2006
    ..05) in IM adipocytes than in other adipocytes. These data support the view that IM fat is not just an ectopic extension of other fat locations but displays specific biological features during growth...
  40. ncbi request reprint Basic principles of muscle development and growth in meat-producing mammals as affected by the insulin-like growth factor (IGF) system
    Niels Oksbjerg
    Department of Animal Nutrition and Physiology, Research Centre Foulum, Danish Institute of Agricultural Sciences, Blichers Alle 1, PO Box 50, DK 8830 Tjele
    Domest Anim Endocrinol 27:219-40. 2004
    ....