Guillaume Jacquot

Summary

Country: France

Publications

  1. pmc Localization of HIV-1 Vpr to the nuclear envelope: impact on Vpr functions and virus replication in macrophages
    Guillaume Jacquot
    Institut Cochin, Universite Paris Descartes, CNRS UMR 8104, Paris, France
    Retrovirology 4:84. 2007
  2. pmc Human immunodeficiency virus type 1 Vpr modulates cellular expression of UNG2 via a negative transcriptional effect
    Christelle Langevin
    Institut Cochin, CNRS UMR 8104, Universite Paris Descartes, Paris, France
    J Virol 83:10256-63. 2009
  3. pmc Characterization of the molecular determinants of primary HIV-1 Vpr proteins: impact of the Q65R and R77Q substitutions on Vpr functions
    Guillaume Jacquot
    Institut Cochin, Universite Paris Descartes, CNRS, UMR 8104, Paris, France
    PLoS ONE 4:e7514. 2009
  4. ncbi request reprint The Siva protein is a novel intracellular ligand of the CD4 receptor that promotes HIV-1 envelope-induced apoptosis in T-lymphoid cells
    Bénédicte Py
    Institut Cochin, CNRS UMR 8104, Universite Paris Descartes, 27 rue du Faubourg Saint Jacques, 75014, Paris, France
    Apoptosis 12:1879-92. 2007
  5. pmc Molecular and functional basis for the scaffolding role of the p50/dynamitin subunit of the microtubule-associated dynactin complex
    Guillaume Jacquot
    Institut Cochin, Universite Paris Descartes, CNRS UMR 8104, Paris, France
    J Biol Chem 285:23019-31. 2010
  6. pmc HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT
    Joshua L Andersen
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America
    PLoS Pathog 2:e127. 2006

Collaborators

Detail Information

Publications6

  1. pmc Localization of HIV-1 Vpr to the nuclear envelope: impact on Vpr functions and virus replication in macrophages
    Guillaume Jacquot
    Institut Cochin, Universite Paris Descartes, CNRS UMR 8104, Paris, France
    Retrovirology 4:84. 2007
    ..In the present study, we have explored the contribution of Vpr accumulation at the NE to the Vpr functions, including G2-arrest and pro-apoptotic activities, and virus replication in primary macrophages...
  2. pmc Human immunodeficiency virus type 1 Vpr modulates cellular expression of UNG2 via a negative transcriptional effect
    Christelle Langevin
    Institut Cochin, CNRS UMR 8104, Universite Paris Descartes, Paris, France
    J Virol 83:10256-63. 2009
    ..Finally, we show that Vpr influences the UNG2 promoter without affecting UNG1 gene expression. These data indicate that the Vpr-induced decrease of UNG2 level is mainly related to a transcriptional effect...
  3. pmc Characterization of the molecular determinants of primary HIV-1 Vpr proteins: impact of the Q65R and R77Q substitutions on Vpr functions
    Guillaume Jacquot
    Institut Cochin, Universite Paris Descartes, CNRS, UMR 8104, Paris, France
    PLoS ONE 4:e7514. 2009
    ..In contradiction with published results, the R77Q substitution, found in LTNP alleles, did not influence Vpr proapoptotic activity...
  4. ncbi request reprint The Siva protein is a novel intracellular ligand of the CD4 receptor that promotes HIV-1 envelope-induced apoptosis in T-lymphoid cells
    Bénédicte Py
    Institut Cochin, CNRS UMR 8104, Universite Paris Descartes, 27 rue du Faubourg Saint Jacques, 75014, Paris, France
    Apoptosis 12:1879-92. 2007
    ..Altogether, these results suggest that Siva-1 might participate in the CD4-initiated signaling apoptotic pathway induced by the HIV-1 envelope in T-lymphoid cells...
  5. pmc Molecular and functional basis for the scaffolding role of the p50/dynamitin subunit of the microtubule-associated dynactin complex
    Guillaume Jacquot
    Institut Cochin, Universite Paris Descartes, CNRS UMR 8104, Paris, France
    J Biol Chem 285:23019-31. 2010
    ..Interestingly, p50/DM self-association does not contribute to p50/DM-induced disruption of the dynactin complex, but most likely participates in the stabilization of the complex...
  6. pmc HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT
    Joshua L Andersen
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America
    PLoS Pathog 2:e127. 2006
    ....