P Menasche

Summary

Country: France

Publications

  1. ncbi request reprint Skeletal myoblast for cell therapy
    Philippe Menasche
    Department of Cardiovascular Surgery and INSERM U 633, Hopital Europeen Georges Pompidou, Paris, France
    Coron Artery Dis 16:105-10. 2005
  2. ncbi request reprint [Role of stem cells in cardiac repair]
    Philippe Menasche
    Service de Chirurgie Cardio Vasculaire de l Hôpital Européen Georges Pompidou INSERM U633 Faculté de Médecine Paris V, Paris, France
    Bull Acad Natl Med 189:615-22; discussion 622-4. 2005
  3. ncbi request reprint Cell transplantation in myocardium
    Philippe Menasche
    Department of Cardiovascular Surgery, Hopital Europeen Georges Pompidou, Paris, France
    Ann Thorac Surg 75:S20-8. 2003
  4. ncbi request reprint Routine delivery of myoblasts during coronary artery bypass surgery: why not?
    Philippe Menasche
    University Paris Descartes, Faculte de Medecine, France
    Nat Clin Pract Cardiovasc Med 3:S90-3. 2006
  5. ncbi request reprint Stem cells for clinical use in cardiovascular medicine: current limitations and future perspectives
    Philippe Menasche
    Hopital Europeen Georges Pompidou, Department of Cardiovascular Surgery, Paris, France
    Thromb Haemost 94:697-701. 2005
  6. ncbi request reprint [Perspectives in cardiac cell therapy]
    Philippe Menasche
    AP HP, Departement de Chirurgie Cardiovasculaire, Hopital Europeen Georges Pompidou, Paris, France
    Presse Med 36:1007-11. 2007
  7. ncbi request reprint The potential of embryonic stem cells to treat heart disease
    Philippe Menasche
    Hôpital Européen Georges Pompidou and Paris Descartes University, Department of Cardiovascular Surgery and INSERM U633, 20 rue Leblanc, Paris 75015, France
    Curr Opin Mol Ther 7:293-9. 2005
  8. ncbi request reprint [Myoblast transplantation for heart failure: where are we heading?]
    P Menasche
    Services de chirurgie cardio vasculaire et de cardiologie, Hopital Europeen Georges Pompidou, Paris
    Arch Mal Coeur Vaiss 98:649-54. 2005
  9. ncbi request reprint Cellular transplantation: hurdles remaining before widespread clinical use
    Philippe Menasche
    Department of Cardiovascular Surgery and INSERM U 572, Hopital Europeen Georges Pompidou, Paris, France
    Curr Opin Cardiol 19:154-61. 2004
  10. ncbi request reprint Skeletal myoblast transplantation for cardiac repair
    Philippe Menasche
    Department of Cardiovascular Surgery, Hopital Europeen Georges Pompidou, Paris, France
    Expert Rev Cardiovasc Ther 2:21-8. 2004

Collaborators

  • M Scorsin
  • Albert A Hagege
  • L Chatenoud
  • Eric Abergel
  • Michel Puceat
  • Jean Thomas Vilquin
  • Alain Bel
  • P Bruneval
  • P Nataf
  • Denis Duboc
  • E Messas
  • Onnik Agbulut
  • Valérie Bellamy
  • Severine Peyrard
  • Etienne Puymirat
  • Julia Pouly
  • D Calderon
  • B Pouzet
  • Guillaume Blin
  • Michel Desnos
  • Hadhami Hamdi
  • Gilbert Dubois
  • Sylvain Chanséaume
  • S You
  • F Valette
  • M Prot
  • V Bellamy
  • J C Wu
  • C Marquet
  • P de Almeida
  • K Schwartz
  • Oriane Guillevic
  • Sonia Stefanovic
  • Benjamin Brinon
  • Elodie Gouadon
  • Shoukhrat Mitalipov
  • Pascal Barbry
  • Catherine Rucker-Martin
  • Jean François Renaud
  • Tui Neri
  • David Nury
  • Chad Cowan
  • Patrice Binder
  • Andre Tomescot
  • Akira Furuta
  • Raghed Geha
  • Jerome Larghero
  • Ludovic Trinquart
  • Chantal Mandet
  • Jean Noel Fabiani
  • Alain Deloche
  • Laurent Sabbah
  • Vincent F M Segers
  • Catherine Amrein
  • Richard T Lee
  • Véronique Bousseaux
  • Suzanne Proksch
  • Romain Guillemain
  • Kasra Azarnoush
  • Agnes Maurel
  • S Ghostine
  • I Garcin
  • M Fiszman

Detail Information

Publications36

  1. ncbi request reprint Skeletal myoblast for cell therapy
    Philippe Menasche
    Department of Cardiovascular Surgery and INSERM U 633, Hopital Europeen Georges Pompidou, Paris, France
    Coron Artery Dis 16:105-10. 2005
    ....
  2. ncbi request reprint [Role of stem cells in cardiac repair]
    Philippe Menasche
    Service de Chirurgie Cardio Vasculaire de l Hôpital Européen Georges Pompidou INSERM U633 Faculté de Médecine Paris V, Paris, France
    Bull Acad Natl Med 189:615-22; discussion 622-4. 2005
    ..Their subsequent electromechanical integration into the recipient myocardium can contribute to the repair of the damaged heart...
  3. ncbi request reprint Cell transplantation in myocardium
    Philippe Menasche
    Department of Cardiovascular Surgery, Hopital Europeen Georges Pompidou, Paris, France
    Ann Thorac Surg 75:S20-8. 2003
    ..In parallel to the experimental studies designed to address these issues clinical trials are under way and should hopefully allow assessing to what extent cell transplantation may improve the outcome of patients with heart failure...
  4. ncbi request reprint Routine delivery of myoblasts during coronary artery bypass surgery: why not?
    Philippe Menasche
    University Paris Descartes, Faculte de Medecine, France
    Nat Clin Pract Cardiovasc Med 3:S90-3. 2006
    ....
  5. ncbi request reprint Stem cells for clinical use in cardiovascular medicine: current limitations and future perspectives
    Philippe Menasche
    Hopital Europeen Georges Pompidou, Department of Cardiovascular Surgery, Paris, France
    Thromb Haemost 94:697-701. 2005
    ....
  6. ncbi request reprint [Perspectives in cardiac cell therapy]
    Philippe Menasche
    AP HP, Departement de Chirurgie Cardiovasculaire, Hopital Europeen Georges Pompidou, Paris, France
    Presse Med 36:1007-11. 2007
    ..Three challenges remain to obtain optimal therapeutic benefits: prevent the migration of these cells, increase their survival, and improve their integration into the recipient myocardium...
  7. ncbi request reprint The potential of embryonic stem cells to treat heart disease
    Philippe Menasche
    Hôpital Européen Georges Pompidou and Paris Descartes University, Department of Cardiovascular Surgery and INSERM U633, 20 rue Leblanc, Paris 75015, France
    Curr Opin Mol Ther 7:293-9. 2005
    ....
  8. ncbi request reprint [Myoblast transplantation for heart failure: where are we heading?]
    P Menasche
    Services de chirurgie cardio vasculaire et de cardiologie, Hopital Europeen Georges Pompidou, Paris
    Arch Mal Coeur Vaiss 98:649-54. 2005
    ..It is therefore critical to go on exploring other paths, among which embryonic stem cells are particularly attractive...
  9. ncbi request reprint Cellular transplantation: hurdles remaining before widespread clinical use
    Philippe Menasche
    Department of Cardiovascular Surgery and INSERM U 572, Hopital Europeen Georges Pompidou, Paris, France
    Curr Opin Cardiol 19:154-61. 2004
    ..It is thus appropriate to review the most important of these studies in light of the major issues that still impede widespread clinical use of cell therapy...
  10. ncbi request reprint Skeletal myoblast transplantation for cardiac repair
    Philippe Menasche
    Department of Cardiovascular Surgery, Hopital Europeen Georges Pompidou, Paris, France
    Expert Rev Cardiovasc Ther 2:21-8. 2004
    ..Altogether, these efforts should allow the assessment of whether and to what extent cell transplantation may ameliorate function of the failing heart...
  11. ncbi request reprint Skeletal muscle satellite cell transplantation
    Philippe Menasche
    Department of Cardiovascular Surgery, Hopital Europeen Georges Pompidou, 20, rue Leblanc, 75015, Paris, France
    Cardiovasc Res 58:351-7. 2003
    ....
  12. ncbi request reprint Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction
    Philippe Menasche
    Assistance Publique Hopitaux de Paris, Department of Cardiovascular Surgery B, Hopital Bichat, Paris, France
    J Am Coll Cardiol 41:1078-83. 2003
    ..This phase I trial was designed to assess the feasibility and safety of autologous skeletal myoblast transplantation in patients with severe ischemic cardiomyopathy...
  13. ncbi request reprint [Perspectives in cardiac cell therapy]
    Philippe Menasche
    Hopitaux de Paris, Hopital Europeen Georges Pompidou, Département de Chirurgie Cardio vasculaire, Universite Paris Descartes, Faculté de Médecine INSERM U 633, AP HP, Paris 75, France
    Presse Med 36:1S55-8. 2007
    ..Three challenges for on optimal therapeutic benefit: prevent cells migration, increase their survival and improve their integration within the recipient myocardium. Many perspectives exist in the field of regeneration of cardiac tissue...
  14. ncbi request reprint [Cellular therapy in cardiology]
    Philippe Menasche
    Departement de Chirurgie Cardiovasculaire, Hopital Europeen Georges Pompidou, Assistance Publique Hopitaux de Paris, Universite Paris 5, INSERM U633, 20, rue Leblanc, 75908 Paris Cedex 15, France
    C R Biol 330:550-6. 2007
    ..In this setting, the greatest promises are currently held by embryonic stem cells...
  15. ncbi request reprint Intramyocardial transplantation of autologous myoblasts: can tissue processing be optimized?
    B Pouzet
    Service de chirurgie cardiovasculaire, Groupe Hospitalier Bichat Claude Bernard, Paris, France
    Circulation 102:III210-5. 2000
    ..This study assessed whether it could be optimized by muscle preconditioning with the local anesthetic bupivacaine or even bypassed with the use of the so-called mince technique...
  16. ncbi request reprint Regeneration of the myocardium: a new role in the treatment of ischemic heart disease?
    A A Hagege
    Faculte de Medecine Necker, Paris V University, and the Department of Cardiology, Hopital Europeen Georges Pompidou, France
    Hypertension 38:1413-5. 2001
    ..Thus, this new procedure might become a useful adjunct to current treatments of severe ischemic heart failure...
  17. ncbi request reprint Is skeletal myoblast transplantation clinically relevant in the era of angiotensin-converting enzyme inhibitors?
    B Pouzet
    Service de chirurgie cardiovasculaire B, Groupe Hospitalier Bichat Claude Bernard, Paris, France
    Circulation 104:I223-8. 2001
    ..This study assessed whether this benefit is still manifested in the clinically relevant setting of a treatment by ACE inhibitors...
  18. ncbi request reprint Pressure-adjusted antegrade brain perfusion for surgery of the aortic aneurysm
    M Scorsin
    Centre Hospitalier Bichat Claude Bernard, Paris, France
    Eur J Cardiothorac Surg 19:108-10. 2001
    ..We report the use of per-aortic antegrade cerebral perfusion regulated by perfusion pressure using a triple lumen cardioplegia catheter thus optimising cerebral flow...
  19. ncbi request reprint The systemic factor: the comparative roles of cardiopulmonary bypass and off-pump surgery in the genesis of patient injury during and following cardiac surgery
    P Menasche
    Department of Cardiovascular Surgery, Hopital Bichat, Paris, France
    Ann Thorac Surg 72:S2260-5; discussion S2265-6, S2267-70. 2001
    ....
  20. ncbi request reprint Cellular therapy in thoracic and cardiovascular disease
    Philippe Menasche
    Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Department of Cardiovascular Surgery, Paris, France
    Ann Thorac Surg 84:339-42. 2007
  21. doi request reprint Control of Immune Response to Allogeneic Embryonic Stem Cells by CD3 Antibody-Mediated Operational Tolerance Induction
    D Calderon
    Universite Paris Descartes, Sorbonne Paris Cité, Paris, France
    Am J Transplant 16:454-67. 2016
    ..These results demonstrate that CD3 antibody administered alone promotes prolonged survival of allogeneic ESC derivatives and thus could prove useful for enhancing cell engraftment in the absence of chronic immunosuppression...
  22. ncbi request reprint Strategies to improve myocardial protection during extracorporeal circulation
    P Menasche
    Department of Cardiovascular Surgery, Hĵpital Bichat, Paris, France
    Shock 16:20-3. 2001
    ..These different approaches will thus be reviewed consecutively...
  23. pmc Cell-based therapy for heart disease: a clinically oriented perspective
    Philippe Menasche
    Department of Cardiovascular Surgery, Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Paris, France
    Mol Ther 17:758-66. 2009
    ..e., the regulator, and are thus unbypassable prerequisites for an effective and streamlined leap from bench to bedside...
  24. pmc A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates
    Guillaume Blin
    INSERM U633, Avenir Program, Embryonic Stem Cells and Cardiogenesis, Evry, France
    J Clin Invest 120:1125-39. 2010
    ..We therefore believe that the SSEA-1+ progenitors that we have described here have the potential to be used in cardiac regenerative medicine...
  25. doi request reprint Composite cell sheets: a further step toward safe and effective myocardial regeneration by cardiac progenitors derived from embryonic stem cells
    Alain Bel
    Assistance Publique Hopitaux de Paris, Department of Cardiovascular Surgery, Hopital Europeen Georges Pompidou, University Paris Descartes, INSERM U633, Paris, France
    Circulation 122:S118-23. 2010
    ..The safety and efficacy of myocardial regeneration using embryonic stem cells are limited by the risk of teratoma and the high rate of cell death...
  26. ncbi request reprint Skeletal myoblasts as a therapeutic agent
    Philippe Menasche
    Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Department of Cardiovascular Surgery, University Paris Descartes, Faculte de Medecine, INSERM U 633, Paris, F 75015, France
    Prog Cardiovasc Dis 50:7-17. 2007
    ..In the setting of this second generation of cells, human cardiac-specified embryonic stem cells may hold the greatest promise...
  27. ncbi request reprint Can erythropoietin improve skeletal myoblast engraftment in infarcted myocardium?
    Sylvain Chanséaume
    INSERM U 633, Laboratoire d Etude des Greffes et Prothèses Cardiaques, Hôpital Broussais Assistance Publique Hôpitaux de Paris, Ecole de Chirurgie, Paris, France
    Interact Cardiovasc Thorac Surg 6:293-7. 2007
    ..In this model, EPO failed to improve myoblast engraftment and postinfarction LV function. These negative findings justify to pursue the search for alternate cell survival-enhancing strategies...
  28. doi request reprint Skeletal myoblasts and cardiac repair
    Philippe Menasche
    Hopital Europeen Georges Pompidou, Department of Cardiovascular Surgery, University Paris 5, Faculte de Medecine, INSERM U 633, Laboratory of Biosurgical Research, Paris, France
    J Mol Cell Cardiol 45:545-53. 2008
    ....
  29. doi request reprint Cardiac stem cells in the real world
    Julia Pouly
    Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Department of Cardiovascular Surgery University Paris 5, Faculty of Medicine, Paris, France
    J Thorac Cardiovasc Surg 135:673-8. 2008
    ..However, data on these endogenous cardiac precursors are primarily derived from animal studies, and their clinical relevance still remains elusive...
  30. doi request reprint Current status and future prospects for cell transplantation to prevent congestive heart failure
    Philippe Menasche
    Department of Cardiovascular Surgery, Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Paris, France
    Semin Thorac Cardiovasc Surg 20:131-7. 2008
    ..Altogether, these observations provide a framework for future research, the results of which will then have to be integrated in the protocol design of second-generation clinical trials...
  31. doi request reprint Cell delivery: intramyocardial injections or epicardial deposition? A head-to-head comparison
    Hadhami Hamdi
    INSERM U 633, Laboratory of Surgical Research, Paris, France
    Ann Thorac Surg 87:1196-203. 2009
    ..This study used skeletal myoblasts to perform a head-to-head comparison of conventional injections with epicardial deposition of scaffold-embedded cells...
  32. ncbi request reprint [Cell therapy: results in Cardiology]
    Philippe Menasche
    Chirurgie cardiovasculaire, Hopital Europeen Georges Pompidou, 20, rue Leblanc 75908 Paris, Universite Paris Descartes, INSERM U633, Paris
    Bull Acad Natl Med 193:559-68; discussion 568-9. 2009
    ..Although several hurdles stand in the way of routine clinical applications, there are serious reasons for hoping that these cells will eventually provide an effective means of repairing diseased myocardial tissue...
  33. doi request reprint Self-assembling peptide nanofibers and skeletal myoblast transplantation in infarcted myocardium
    Gilbert Dubois
    Assistance Publique Hopitaux de Paris, Ecole de Chirurgie, Paris 75005, France
    J Biomed Mater Res B Appl Biomater 87:222-8. 2008
    ..These data suggest that the optimal use of biomaterial scaffolds for survival of transplanted cells will require specific tailoring of the biomaterial to the cell type...
  34. pmc Can mesenchymal stem cells induce tolerance to cotransplanted human embryonic stem cells?
    Etienne Puymirat
    INSERM U633, Laboratory of Biosurgical Research, Hopital Broussais, Paris, France
    Mol Ther 17:176-82. 2009
    ..However, there was only modest evidence for an immunosuppressive effect of coinjected MSCs and their beneficial effects seemed rather mediated by trophic effects on the host tissue...
  35. doi request reprint A new absorbable collagen membrane to reduce adhesions in cardiac surgery
    Alain Bel
    Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Department of Cardiovascular Surgery, Ecole de Chirurgie, 75908 Paris, France
    Interact Cardiovasc Thorac Surg 10:213-6. 2010
    ..0 [0;3.5] vs. 5.5 [3;7], P=0.01 by Wilcoxon test). The Cova CARD membrane might represent an attractive pericardial substitute for preventing postoperative adhesions in cardiac surgery...
  36. pmc Relief of mitral leaflet tethering following chronic myocardial infarction by chordal cutting diminishes left ventricular remodeling
    Emmanuel Messas
    Hopital Europeen Georges Pompidou, Department of Cardiology, University Paris Descartes, Paris
    Circ Cardiovasc Imaging 3:679-86. 2010
    ..The purpose of this study was to test whether this technique reduces the progression of LV remodeling in the chronic ischemic MR setting...