Meral Esen

Summary

Country: Germany

Publications

  1. doi Safety and immunogenicity of GMZ2 - a MSP3-GLURP fusion protein malaria vaccine candidate
    Meral Esen
    University of Tubingen, Institute of Tropical Medicine, Wilhelmstrasse 27, D 72074 Tubingen, Germany
    Vaccine 27:6862-8. 2009
  2. pmc Humoral immune response to Plasmodium falciparum vaccine candidate GMZ2 and its components in populations naturally exposed to seasonal malaria in Ethiopia
    Hassen Mamo
    Microbial, Cellular and Molecular Biology Department, College of Natural Sciences, Addis Ababa University, P, O, Box 1176, Addis Ababa, Ethiopia
    Malar J 12:51. 2013
  3. doi Effect of IL-15 on IgG versus IgE antibody-secreting cells in vitro
    Meral Esen
    Institute of Tropical Medicine, University of Tubingen, Wilhelmstraße 27, D 72074 Tubingen, Germany
    J Immunol Methods 375:7-13. 2012
  4. doi Assessment of humoral immune responses in malaria vaccine trials
    Meral Esen
    Institut fur Tropenmedizin, Eberhard Karls Universitat Tubingen, Tubingen, Germany
    Wien Klin Wochenschr 122:4-6. 2010
  5. pmc A flow cytometry-based workflow for detection and quantification of anti-plasmodial antibodies in vaccinated and naturally exposed individuals
    Anthony Ajua
    Institute of Tropical Medicine, University of Tubingen, Wilhelmstraße 27, Tübingen D 72074, Germany
    Malar J 11:367. 2012
  6. doi Expression of interleukin-6 family receptors in NK92 cells is regulated by cytokines and not through direct interaction with Plasmodium falciparum-infected erythrocytes
    Evelyn Böttger
    Institute for Tropical Medicine, Tubingen University, Tubingen, Germany
    J Interferon Cytokine Res 33:65-71. 2013
  7. doi Reduced antibody responses against Plasmodium falciparum vaccine candidate antigens in the presence of Trichuris trichiura
    Meral Esen
    Institute of Tropical Medicine, University of Tubingen, Tubingen, Germany
    Vaccine 30:7621-4. 2012
  8. doi Population structure of Legionella spp. from environmental samples in Gabon, 2013
    Jonas Ehrhardt
    Institut fur Tropenmedizin, Eberhard Karls Universitat Tubingen, Deutsches Zentrum für Infektionsforschung, Tubingen, Germany Centre de Recherches Médicales de Lambaréné CERMEL, Lambarene, Gabon
    Infect Genet Evol 33:299-303. 2015
  9. pmc Effect of Antihelminthic Treatment on Vaccine Immunogenicity to a Seasonal Influenza Vaccine in Primary School Children in Gabon: A Randomized Placebo-Controlled Trial
    Sina Brückner
    Institute of Tropical Medicine, University of Tubingen, Tubingen, Germany Centre de Recherches Médicales de Lambaréné, Albert Schweitzer Hospital, Lambarene, Gabon
    PLoS Negl Trop Dis 9:e0003768. 2015
  10. pmc Naturally acquired immune responses to malaria vaccine candidate antigens MSP3 and GLURP in Guahibo and Piaroa indigenous communities of the Venezuelan Amazon
    Andreas Baumann
    Institut fur Tropenmedizin, Eberhard Karls Universitat Tubingen, Tubingen, Germany
    Malar J 11:46. 2012

Collaborators

Detail Information

Publications12

  1. doi Safety and immunogenicity of GMZ2 - a MSP3-GLURP fusion protein malaria vaccine candidate
    Meral Esen
    University of Tubingen, Institute of Tropical Medicine, Wilhelmstrasse 27, D 72074 Tubingen, Germany
    Vaccine 27:6862-8. 2009
    ..We conclude that GMZ2 is a safe and immunogenic malaria vaccine candidate suitable for further clinical development...
  2. pmc Humoral immune response to Plasmodium falciparum vaccine candidate GMZ2 and its components in populations naturally exposed to seasonal malaria in Ethiopia
    Hassen Mamo
    Microbial, Cellular and Molecular Biology Department, College of Natural Sciences, Addis Ababa University, P, O, Box 1176, Addis Ababa, Ethiopia
    Malar J 12:51. 2013
    ..In Ethiopia, the general population is vulnerable to unpredictable epidemics of Plasmodium falciparum malaria. However, there is little information on the anti-malaria immune profile of the population in the endemic regions of the country...
  3. doi Effect of IL-15 on IgG versus IgE antibody-secreting cells in vitro
    Meral Esen
    Institute of Tropical Medicine, University of Tubingen, Wilhelmstraße 27, D 72074 Tubingen, Germany
    J Immunol Methods 375:7-13. 2012
    ..We show that our method is suitable for the detection of specific and non-specific IgE-ASCs and IgG-ASCs and allows the investigation of the interplay between IgG-ASCs and IgE-ASCs in different populations...
  4. doi Assessment of humoral immune responses in malaria vaccine trials
    Meral Esen
    Institut fur Tropenmedizin, Eberhard Karls Universitat Tubingen, Tubingen, Germany
    Wien Klin Wochenschr 122:4-6. 2010
    ..The group for clinical trials and immunology is the interphase for the establishment of immunological assays and their implementation in clinical trials...
  5. pmc A flow cytometry-based workflow for detection and quantification of anti-plasmodial antibodies in vaccinated and naturally exposed individuals
    Anthony Ajua
    Institute of Tropical Medicine, University of Tubingen, Wilhelmstraße 27, Tübingen D 72074, Germany
    Malar J 11:367. 2012
    ..A novel, cytometry-based workflow for quantitative detection of anti-plasmodial antibodies in human serum is presented...
  6. doi Expression of interleukin-6 family receptors in NK92 cells is regulated by cytokines and not through direct interaction with Plasmodium falciparum-infected erythrocytes
    Evelyn Böttger
    Institute for Tropical Medicine, Tubingen University, Tubingen, Germany
    J Interferon Cytokine Res 33:65-71. 2013
    ..This finding encourages future studies in a more physiological context and with primary cells isolated from humans with and without malaria...
  7. doi Reduced antibody responses against Plasmodium falciparum vaccine candidate antigens in the presence of Trichuris trichiura
    Meral Esen
    Institute of Tropical Medicine, University of Tubingen, Tubingen, Germany
    Vaccine 30:7621-4. 2012
    ..Therefore we assessed the influence of helminth infection on vaccine-induced immune responses in a phase I clinical trial of the malaria vaccine candidate GMZ2...
  8. doi Population structure of Legionella spp. from environmental samples in Gabon, 2013
    Jonas Ehrhardt
    Institut fur Tropenmedizin, Eberhard Karls Universitat Tubingen, Deutsches Zentrum für Infektionsforschung, Tubingen, Germany Centre de Recherches Médicales de Lambaréné CERMEL, Lambarene, Gabon
    Infect Genet Evol 33:299-303. 2015
    ..in the studied areas in Gabon, particularly if they have risk factors such as comorbidities. Both broadly extended (ST1, ST75) and local lineages (ST1911) were present in our setting...
  9. pmc Effect of Antihelminthic Treatment on Vaccine Immunogenicity to a Seasonal Influenza Vaccine in Primary School Children in Gabon: A Randomized Placebo-Controlled Trial
    Sina Brückner
    Institute of Tropical Medicine, University of Tubingen, Tubingen, Germany Centre de Recherches Médicales de Lambaréné, Albert Schweitzer Hospital, Lambarene, Gabon
    PLoS Negl Trop Dis 9:e0003768. 2015
    ..In the present study we investigated whether a single-dose antihelminthic treatment influences antibody responses to a seasonal influenza vaccine in primary school children living in Gabon, Central Africa...
  10. pmc Naturally acquired immune responses to malaria vaccine candidate antigens MSP3 and GLURP in Guahibo and Piaroa indigenous communities of the Venezuelan Amazon
    Andreas Baumann
    Institut fur Tropenmedizin, Eberhard Karls Universitat Tubingen, Tubingen, Germany
    Malar J 11:46. 2012
    ..Malaria transmission in most of Latin America can be considered as controlled. In such a scenario, parameters of baseline immunity to malaria antigens are of specific interest with respect to future malaria eradication efforts...
  11. pmc Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres
    Benjamin Mordmuller
    Institut fur Tropenmedizin, Eberhard Karls Universität Tübingen and German Center for Infection Research, 72074, Tubingen, Germany
    Malar J 14:117. 2015
    ..Mosquito-mediated CHMI is logistically complex, exact PfSPZ dosage is impossible and live mosquito-based interventions are not suitable for further clinical development...
  12. pmc Plasmodium falciparum-infected erythrocytes induce granzyme B by NK cells through expression of host-Hsp70
    Evelyn Böttger
    Institute for Tropical Medicine, Tubingen University, Tubingen, Germany
    PLoS ONE 7:e33774. 2012
    ....