T Graf

Summary

Affiliation: European Molecular Biology Laboratory
Country: Germany

Publications

  1. ncbi request reprint Leukemogenesis: small differences in Myb have large effects
    T Graf
    EMBL, Heidelberg, Germany
    Curr Biol 8:R353-5. 1998
  2. ncbi request reprint The nuclear oncogenes v-erbA and v-ets cooperate in the induction of avian erythroleukemia
    T Metz
    Differentiation Programme, European Molecular Biology Laboratory, Heidelberg, Germany
    Oncogene 7:597-605. 1992
  3. ncbi request reprint Fusion of the nuclear oncoproteins v-Myb and v-Ets is required for the leukemogenicity of E26 virus
    T Metz
    Differentiation Programme European Molecular Biology Laboratory, Heidelberg, Germany
    Cell 66:95-105. 1991
  4. ncbi request reprint Rem-1, a putative direct target gene of the Myb-Ets fusion oncoprotein in haematopoietic progenitors, is a member of the recoverin family
    N Kraut
    Differentiation Programme, European Molecular Biology Laboratory, Heidelberg, Germany
    Oncogene 10:1027-36. 1995
  5. pmc Cooperative interaction of ets-1 with USF-1 required for HIV-1 enhancer activity in T cells
    M H Sieweke
    EMBL, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    EMBO J 17:1728-39. 1998
  6. ncbi request reprint Goose-type lysozyme gene of the chicken: sequence, genomic organization and expression reveals major differences to chicken-type lysozyme gene
    T Nakano
    European Molecular Biology Laboratory, Heidelberg, Germany
    Biochim Biophys Acta 1090:273-6. 1991
  7. ncbi request reprint The eosinophil-specific cell surface antigen, EOS47, is a chicken homologue of the oncofetal antigen melanotransferrin
    K M McNagny
    Differentiation Program, European Molecular Biology Laboratory, Heidelberg, Germany
    Blood 87:1343-52. 1996
  8. ncbi request reprint Bicistronic retroviral vector reveals capacity of v-erbA to induce erythroleukemia and to co-operate with v-myb
    T Casini
    Differentiation Programme, European Molecular Biology Laboratory, Heidelberg, Germany
    Oncogene 11:1019-26. 1995
  9. ncbi request reprint A transcription factor party during blood cell differentiation
    M H Sieweke
    European Molecular Biology Laboratory, Meyerhofstr 1, 69117, Heidelberg, Germany
    Curr Opin Genet Dev 8:545-51. 1998
  10. ncbi request reprint Proposed structure for the DNA-binding domain of the Myb oncoprotein based on model building and mutational analysis
    J Frampton
    European Molecular Biology Laboratory, Heidelberg, Germany
    Protein Eng 4:891-901. 1991

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Leukemogenesis: small differences in Myb have large effects
    T Graf
    EMBL, Heidelberg, Germany
    Curr Biol 8:R353-5. 1998
    ..Surprisingly, these two mutant forms of Myb differ in the subsets of myeloid cells that they transform, the target genes that they activate, and the way in which they are regulated...
  2. ncbi request reprint The nuclear oncogenes v-erbA and v-ets cooperate in the induction of avian erythroleukemia
    T Metz
    Differentiation Programme, European Molecular Biology Laboratory, Heidelberg, Germany
    Oncogene 7:597-605. 1992
    ..These data demonstrate that two separately expressed nuclear oncoproteins can complement each other in vitro and in vivo. They also show that the v-Ets protein on its own can contribute to leukemogenesis...
  3. ncbi request reprint Fusion of the nuclear oncoproteins v-Myb and v-Ets is required for the leukemogenicity of E26 virus
    T Metz
    Differentiation Programme European Molecular Biology Laboratory, Heidelberg, Germany
    Cell 66:95-105. 1991
    ..These results show that v-Myb and v-Ets must be fused to cause leukemia and establish a new mechanism of oncogene activation and cooperation...
  4. ncbi request reprint Rem-1, a putative direct target gene of the Myb-Ets fusion oncoprotein in haematopoietic progenitors, is a member of the recoverin family
    N Kraut
    Differentiation Programme, European Molecular Biology Laboratory, Heidelberg, Germany
    Oncogene 10:1027-36. 1995
    ..Enforced expression of rem-1 in ts1.1-transformed MEP cells, using a retroviral vector, showed that this gene is not sufficient to block their differentiation, but that it may provide them with a growth advantage...
  5. pmc Cooperative interaction of ets-1 with USF-1 required for HIV-1 enhancer activity in T cells
    M H Sieweke
    EMBL, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    EMBO J 17:1728-39. 1998
    ..Together these results indicate that the interaction between Ets-1 and USF-1 is required for full transcriptional activity of the HIV-1 LTR in T cells...
  6. ncbi request reprint Goose-type lysozyme gene of the chicken: sequence, genomic organization and expression reveals major differences to chicken-type lysozyme gene
    T Nakano
    European Molecular Biology Laboratory, Heidelberg, Germany
    Biochim Biophys Acta 1090:273-6. 1991
    ..In addition, goose-type lysozyme displays an overlapping but different tissue expression pattern in chickens than chicken-type lysozyme...
  7. ncbi request reprint The eosinophil-specific cell surface antigen, EOS47, is a chicken homologue of the oncofetal antigen melanotransferrin
    K M McNagny
    Differentiation Program, European Molecular Biology Laboratory, Heidelberg, Germany
    Blood 87:1343-52. 1996
    ..Our results show that melanotransferrin is a stage-specific marker of eosinophils and should be useful for their isolation and further characterization...
  8. ncbi request reprint Bicistronic retroviral vector reveals capacity of v-erbA to induce erythroleukemia and to co-operate with v-myb
    T Casini
    Differentiation Programme, European Molecular Biology Laboratory, Heidelberg, Germany
    Oncogene 11:1019-26. 1995
    ....
  9. ncbi request reprint A transcription factor party during blood cell differentiation
    M H Sieweke
    European Molecular Biology Laboratory, Meyerhofstr 1, 69117, Heidelberg, Germany
    Curr Opin Genet Dev 8:545-51. 1998
    ....
  10. ncbi request reprint Proposed structure for the DNA-binding domain of the Myb oncoprotein based on model building and mutational analysis
    J Frampton
    European Molecular Biology Laboratory, Heidelberg, Germany
    Protein Eng 4:891-901. 1991
    ..Modelling also allowed positioning of adjacent repeats around the major groove over an 8 bp binding site...
  11. ncbi request reprint Identification of genes differentially expressed in two types of v-myb-transformed avian myelomonocytic cells
    T Nakano
    Differentiation Programme, European Molecular Biology Laboratory, Heidelberg, Germany
    Oncogene 7:527-34. 1992
    ..Co-transfection experiments of a reporter construct containing the promoter of the ribonuclease A-related gene indicated that this promoter is regulated by the v-Myb oncoprotein without the involvement of Myb-specific binding sequences...