Marc Birringer

Summary

Affiliation: Friedrich Schiller University
Country: Germany

Publications

  1. ncbi Improved glucose metabolism in mice lacking alpha-tocopherol transfer protein
    Marc Birringer
    Dept of Human Nutrition, Inst of Nutrition, University of Jena, Dornburger Strasse 29, 07743, Jena, Germany
    Eur J Nutr 46:397-405. 2007
  2. doi Proapoptotic effects of long-chain vitamin E metabolites in HepG2 cells are mediated by oxidative stress
    Marc Birringer
    Department of Human Nutrition, Institute of Nutrition, Friedrich Schiller University of Jena, Jena, Germany
    Free Radic Biol Med 49:1315-22. 2010
  3. doi Analysis of vitamin E metabolites in biological specimen
    Marc Birringer
    Department of Human Nutrition, Institute of Nutrition, Friedrich Schiller University, Jena, Germany
    Mol Nutr Food Res 54:588-98. 2010
  4. ncbi Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress
    Tim J Schulz
    Department of Human Nutrition, Institute of Nutrition, University of Jena, D 07743 Jena, Germany
    Cell Metab 6:280-93. 2007
  5. pmc Antioxidants prevent health-promoting effects of physical exercise in humans
    Michael Ristow
    Department of Human Nutrition, Institute of Nutrition, University of Jena, Jena D 07743, Germany
    Proc Natl Acad Sci U S A 106:8665-70. 2009
  6. doi α-Tocopherol long-chain metabolite α-13'-COOH affects the inflammatory response of lipopolysaccharide-activated murine RAW264.7 macrophages
    Maria Wallert
    Department of Nutritional Biochemistry and Physiology, Institute of Nutrition, Friedrich Schiller University Jena, Jena, Germany
    Mol Nutr Food Res 59:1524-34. 2015
  7. pmc Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide
    Kathrin Schmeisser
    1 Department of Human Nutrition, Institute of Nutrition, University of Jena, Jena, Germany 2
    Nat Chem Biol 9:693-700. 2013
  8. ncbi In vitro fermented nuts exhibit chemopreventive effects in HT29 colon cancer cells
    Stefanie Lux
    Department of Nutritional Toxicology, Institute of Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 24, Jena, Germany
    Br J Nutr 108:1177-86. 2012
  9. pmc Variable expression of Cre recombinase transgenes precludes reliable prediction of tissue-specific gene disruption by tail-biopsy genotyping
    Tim J Schulz
    University of Jena, Institute of Nutrition, Jena, Germany
    PLoS ONE 2:e1013. 2007
  10. doi Small-molecule targeting of the mitochondrial compartment with an endogenously cleaved reversible tag
    Jens Ripcke
    Department of Human Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 29, Jena, Germany
    Chembiochem 10:1689-96. 2009

Collaborators

Detail Information

Publications14

  1. ncbi Improved glucose metabolism in mice lacking alpha-tocopherol transfer protein
    Marc Birringer
    Dept of Human Nutrition, Inst of Nutrition, University of Jena, Dornburger Strasse 29, 07743, Jena, Germany
    Eur J Nutr 46:397-405. 2007
    ..The alpha-tocopherol transfer protein (alpha-TTP) mediates the transfer of alpha-tocopherol (alpha-TOH) from hepatocytes to very-low-density lipoproteins, thereby controlling plasma levels of alpha-TOH...
  2. doi Proapoptotic effects of long-chain vitamin E metabolites in HepG2 cells are mediated by oxidative stress
    Marc Birringer
    Department of Human Nutrition, Institute of Nutrition, Friedrich Schiller University of Jena, Jena, Germany
    Free Radic Biol Med 49:1315-22. 2010
    ..Taken together, these results indicate that long-chain metabolites may be responsible for antiproliferative properties of vitamin E vitamers...
  3. doi Analysis of vitamin E metabolites in biological specimen
    Marc Birringer
    Department of Human Nutrition, Institute of Nutrition, Friedrich Schiller University, Jena, Germany
    Mol Nutr Food Res 54:588-98. 2010
    ..Special emphasis is laid on analytical applications for the identification and quantification of metabolites with a modified hydroxychromanol ring or a truncated side chain...
  4. ncbi Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress
    Tim J Schulz
    Department of Human Nutrition, Institute of Nutrition, University of Jena, D 07743 Jena, Germany
    Cell Metab 6:280-93. 2007
    ....
  5. pmc Antioxidants prevent health-promoting effects of physical exercise in humans
    Michael Ristow
    Department of Human Nutrition, Institute of Nutrition, University of Jena, Jena D 07743, Germany
    Proc Natl Acad Sci U S A 106:8665-70. 2009
    ..Supplementation with antioxidants may preclude these health-promoting effects of exercise in humans...
  6. doi α-Tocopherol long-chain metabolite α-13'-COOH affects the inflammatory response of lipopolysaccharide-activated murine RAW264.7 macrophages
    Maria Wallert
    Department of Nutritional Biochemistry and Physiology, Institute of Nutrition, Friedrich Schiller University Jena, Jena, Germany
    Mol Nutr Food Res 59:1524-34. 2015
    ..The long-chain metabolite α-13'-carboxychromanol (α-13'-COOH) is formed by hepatic α-tocopherol (α-TOH) catabolism and acts as a regulatory metabolite via pathways that are different from its metabolic precursor...
  7. pmc Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide
    Kathrin Schmeisser
    1 Department of Human Nutrition, Institute of Nutrition, University of Jena, Jena, Germany 2
    Nat Chem Biol 9:693-700. 2013
    ..elegans longevity. Taken together, sirtuin-mediated lifespan extension depends on methylation of NAM, providing an unexpected mechanistic role for sirtuins beyond histone deacetylation. ..
  8. ncbi In vitro fermented nuts exhibit chemopreventive effects in HT29 colon cancer cells
    Stefanie Lux
    Department of Nutritional Toxicology, Institute of Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 24, Jena, Germany
    Br J Nutr 108:1177-86. 2012
    ....
  9. pmc Variable expression of Cre recombinase transgenes precludes reliable prediction of tissue-specific gene disruption by tail-biopsy genotyping
    Tim J Schulz
    University of Jena, Institute of Nutrition, Jena, Germany
    PLoS ONE 2:e1013. 2007
    ..This indicates that sustained post hoc analyses in regards to efficacy of disruption for every single study group member may be required...
  10. doi Small-molecule targeting of the mitochondrial compartment with an endogenously cleaved reversible tag
    Jens Ripcke
    Department of Human Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 29, Jena, Germany
    Chembiochem 10:1689-96. 2009
    ..Overall, reversible tagging combines decreased tag-related cytotoxicity with increased bioactivity, and this potentially provides a novel concept in mitochondrial pharmacology...
  11. pmc Complexity of vitamin E metabolism
    Lisa Schmölz
    Lisa Schmölz, Stefan Lorkowski, Maria Wallert, Department of Nutritional Biochemistry and Physiology, Institute of Nutrition, Friedrich Schiller University Jena, Germany and Competence Center for Nutrition and Cardiovascular Health, Halle Jena Leipzig, 07743 Jena, Germany
    World J Biol Chem 7:14-43. 2016
    ..To evaluate individual vitamin E status, the analytical procedures used for detecting and quantifying vitamin E and its metabolites are crucial. The latest methods in analytics are presented. ..
  12. pmc Regulatory metabolites of vitamin E and their putative relevance for atherogenesis
    Maria Wallert
    Department of Nutritional Biochemistry, Institute of Nutrition, Friedrich Schiller University Jena, Germany
    Redox Biol 2:495-503. 2014
    ..We speculate that the metabolites contribute to physiological as well as pathophysiological processes. ..
  13. doi Long-chain metabolites of α-tocopherol occur in human serum and inhibit macrophage foam cell formation in vitro
    Maria Wallert
    Department of Nutritional Biochemistry, Institute of Nutrition, Friedrich Schiller University Jena, 07743 Jena, Germany
    Free Radic Biol Med 68:43-51. 2014
    ..We speculate that α-LCMs represent a new class of regulatory metabolites. Further studies are required to elucidate their physiological role and contribution to cardiovascular disease. ..
  14. ncbi Impaired respiration is positively correlated with decreased life span in Caenorhabditis elegans models of Friedreich Ataxia
    Kim Zarse
    Department of Human Nutrition, Inst of Nutrition, University of Jena, 29 Dornburger St, Jena D 07743, Germany
    FASEB J 21:1271-5. 2007
    ..Taken together, impaired mitochondrial metabolism due to RNAi-mediated inhibition of the frataxin homologue frh-1 causes both impaired respiration as well as decreased life span in the multicellular eukaryote C. elegans...