J S Ahmed

Summary

Affiliation: Research Center Borstel
Country: Germany

Publications

  1. ncbi Review: Theileria schizonts induce fundamental alterations in their host cells
    J S Ahmed
    Forschungszentrum Borstel, Germany
    Parasitol Res 85:527-38. 1999
  2. ncbi Current status of ticks in Asia
    Jabbar Ahmed
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Parkallee 22, 23845, Borstel, Germany
    Parasitol Res 101:S159-62. 2007
  3. ncbi Ovine theileriosis in China: a new look at an old story
    Hong Yin
    Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China
    Parasitol Res 101:S191-5. 2007
  4. ncbi The Asian and European collaborative network: the Asian component of the integrated consortium on ticks and tick-borne diseases
    Jabbar S Ahmed
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Parkallee 22, 23845, Borstel, Germany
    Parasitol Res 101:S157-8. 2007
  5. doi Innate immunity to tropical theileriosis
    Jabbar S Ahmed
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Borstel, Germany
    Innate Immun 14:5-12. 2008
  6. doi Animal health: harmonisation and distribution of pathogen detection and differentiation tools
    J S Ahmed
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, 23845 Borstel, Germany
    Transbound Emerg Dis 55:187-9. 2008
  7. ncbi Phylogenetic position of small-ruminant infecting piroplasms
    Jabbar S Ahmed
    Division of Veterinary Infectiology and Immunology, Research Center Borstel, Parkallee 22, 23845 Borstel, Germany
    Ann N Y Acad Sci 1081:498-504. 2006
  8. ncbi Ticks and tick-borne diseases in Asia with special emphasis on China
    Jabbar Ahmed
    Research Center Borstel, Germany
    Parasitol Res 88:S51-5. 2002
  9. ncbi Generation of cytotoxic T lymphocytes and cytostatic acting cells in T. annulata-immune cattle
    J S Ahmed
    Forschungszentrum Borstel, Parkallee 22, 23845 Borstel, Germany
    Ann N Y Acad Sci 916:595-9. 2000
  10. ncbi The role of cytokines in immunity and immunopathogenesis of pirolasmoses
    J S Ahmed
    Research Center Borstel, Center for Medicine in Biosciences, Germany
    Parasitol Res 88:S48-50. 2002

Collaborators

Detail Information

Publications45

  1. ncbi Review: Theileria schizonts induce fundamental alterations in their host cells
    J S Ahmed
    Forschungszentrum Borstel, Germany
    Parasitol Res 85:527-38. 1999
    ..A possible candidate may the casein kinase II homologue that was identified in schizonts of both T. annulata and T. parva...
  2. ncbi Current status of ticks in Asia
    Jabbar Ahmed
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Parkallee 22, 23845, Borstel, Germany
    Parasitol Res 101:S159-62. 2007
    ..Besides the knowledge dissemination, this meeting resulted in a number of achievements such as the establishment of working groups for epidemiological studies and distribution of tick differentiation protocols and diagnostic tools...
  3. ncbi Ovine theileriosis in China: a new look at an old story
    Hong Yin
    Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China
    Parasitol Res 101:S191-5. 2007
    ..We report on the existence of at least two additional ovine and caprine piroplasm species, designated T. luwenshuni and T. uilenbergi...
  4. ncbi The Asian and European collaborative network: the Asian component of the integrated consortium on ticks and tick-borne diseases
    Jabbar S Ahmed
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Parkallee 22, 23845, Borstel, Germany
    Parasitol Res 101:S157-8. 2007
  5. doi Innate immunity to tropical theileriosis
    Jabbar S Ahmed
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Borstel, Germany
    Innate Immun 14:5-12. 2008
    ..In addition, the latest findings concerning cattle breed differences in susceptibility to T. annulata infection in relation to macrophage activation are discussed...
  6. doi Animal health: harmonisation and distribution of pathogen detection and differentiation tools
    J S Ahmed
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, 23845 Borstel, Germany
    Transbound Emerg Dis 55:187-9. 2008
    ..The aim of this collaborative network was to: 1 Distribute and harmonize diagnostic tools required for pathogen detection and differentiation. 2 Build the capacity to ensure the conduction of integrated disease control measures...
  7. ncbi Phylogenetic position of small-ruminant infecting piroplasms
    Jabbar S Ahmed
    Division of Veterinary Infectiology and Immunology, Research Center Borstel, Parkallee 22, 23845 Borstel, Germany
    Ann N Y Acad Sci 1081:498-504. 2006
    ..In addition, these studies revealed the existence of at least two novel sheep/goat piroplasm species, designated Theileria sp. (China 1) and Theileria sp. (China 2)...
  8. ncbi Ticks and tick-borne diseases in Asia with special emphasis on China
    Jabbar Ahmed
    Research Center Borstel, Germany
    Parasitol Res 88:S51-5. 2002
    ..In addition, progress made in immunity and vaccine development against the pathogens mentioned above and their vector ticks was also discussed...
  9. ncbi Generation of cytotoxic T lymphocytes and cytostatic acting cells in T. annulata-immune cattle
    J S Ahmed
    Forschungszentrum Borstel, Parkallee 22, 23845 Borstel, Germany
    Ann N Y Acad Sci 916:595-9. 2000
    ..The growth inhibition of CAC is MHC unrestricted, and not mediated by cytokine interferon gamma (IFN-gamma)...
  10. ncbi The role of cytokines in immunity and immunopathogenesis of pirolasmoses
    J S Ahmed
    Research Center Borstel, Center for Medicine in Biosciences, Germany
    Parasitol Res 88:S48-50. 2002
    ..The latter cells kill Theileria-infected host leucocytes in an MHC class I-dependent manner. On the other hand, the overproduction of proinflammatory cytokines contributes to disease progress...
  11. ncbi Lymphocyte stimulatory capacity of Theileria annulata-infected ovine lymphoblastoid cells
    J S Ahmed
    Forschungszentrum Borstel, Parkallee 22, 23845 Borstel, Germany
    Ann N Y Acad Sci 916:276-82. 2000
    ..The peak response was observed on day three or four and the response could not be induced by lysates of infected cells or their supernatants. The stimulated cells expressed IL-2 and secreted an IL-2-like growth factor...
  12. doi Cytoplasmic sequestration of p53 promotes survival in leukocytes transformed by Theileria
    D Haller
    Division of Veterinary Infection Biology and Immunology, Department of Immunology and Cell Biology, Research Center Borstel, Borstel, Germany
    Oncogene 29:3079-86. 2010
    ....
  13. ncbi A new recombinant protein-based ELISA for the diagnosis of malignant theileriosis of sheep and goats
    M A Bakheit
    Division of Veterinary Infectiology and Immunology, Research Center Borstel, Parkallee 22, 23845 Borstel, Germany
    Parasitol Res 98:145-9. 2006
    ..Moreover, no cross-reactions could be demonstrated against Theileria species (China) nor Cowdria spp. This test is recommended for further field validation experiments...
  14. ncbi Phylogenetic analysis by rRNA comparison of the highly pathogenic sheep-infecting parasites Theileria lestoquardi and a Theileria species identified in China
    L Schnittger
    Forschungszentrum Borstel, Parkallee 22, 23845 Borstel, Germany
    Ann N Y Acad Sci 916:271-5. 2000
    ..On the other hand, it was clearly divergent to a lineage of lymphoproliferative Theileria species; T. annulata, T. parva, T. taurotragi, and T. lestoquardi, the latter being most closely related to T. annulata...
  15. doi Development of a competitive ELISA for detection of Theileria annulata infection
    S Renneker
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Parkallee 22, 23845 Borstel, Germany
    Transbound Emerg Dis 55:249-56. 2008
    ..Thus the test proved its suitability for the diagnosis of tropical theileriosis and has application for use in serological surveys to monitor the prevalence of the disease or identify carrier animals with high specificity...
  16. doi Development and evaluation of a loop-mediated isothermal amplification method for diagnosis of tropical theileriosis
    D A Salih
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Parkallee 22, D 23845 Borstel, Germany
    Transbound Emerg Dis 55:238-43. 2008
    ..These results indicate that the LAMP assay is rapid and simple to run, cost-effective, sensitive and specific and has potential usefulness for application in epidemiological studies on T. annulata infection of cattle...
  17. doi Evaluation of Theileria annulata recombinant immunodominant proteins for the development of ELISA
    U Seitzer
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Parkallee 22, 23845 Borstel, Germany
    Transbound Emerg Dis 55:244-8. 2008
    ..annulata proteins tested, all three having been described or predicted to be parasite membrane proteins. The outstanding performance of the TaSP protein for detection of T. annulata infection in indirect ELISA was confirmed...
  18. doi Development of a loop-mediated isothermal amplification (LAMP) assay for rapid diagnosis of Babesia canis infections
    H Muller
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Borstel, Germany
    Transbound Emerg Dis 57:63-5. 2010
    ..In this study, we aimed to establish a rapid and easy to perform DNA-based test using loop-mediated isothermal amplification to detect all three Babesia canis subspecies in one assay...
  19. ncbi Determination of potential risk factors associated with Theileria annulata and Theileria parva infections of cattle in the Sudan
    D A Salih
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Parkallee 22, 23845, Borstel, Germany
    Parasitol Res 101:1285-8. 2007
    ..parva locations and seasons could be held as risk factors in Southern Sudan. The results of this study will assist in the development of more effective control strategies for smallholder dairy farms in the country...
  20. ncbi Characterization of a polymorphic gene of T. lestoquardi and of a recently identified Theileria species pathogenic for small ruminants in China
    L Schnittger
    Forschungszentrum Borstel, Parkallee 22, 23845 Borstel, Germany
    Parasitol Res 88:553-6. 2002
    ....
  21. ncbi Application of the recombinant Theileria annulata surface protein in an indirect ELISA for the diagnosis of tropical theileriosis
    M A Bakheit
    Forschungszentrum Borstel, Parkallee 22, 23845 Borstel, Germany
    Parasitol Res 92:299-302. 2004
    ..Our test has proved its suitability for the diagnosis of tropical theileriosis and could be used in serological surveys to map out the prevalence of the disease or to monitor vaccination efficiencies in disease-free populations...
  22. ncbi Molecular characterization of a Theileria lestoquardi gene encoding for immunogenic protein splice variants
    M A Bakheit
    Division of Veterinary Infectiology and Immunology, Research Center Borstel, Parkallee 22, 23845, Borstel, Germany
    Parasitol Res 100:161-70. 2006
    ..Both recombinantly produced forms were found to be reactive with sera from infected animals. Bioinformatic analyses were employed to address the possible function of the gene products in the biology of T. lestoquardi...
  23. doi Tropical theileriosis: cytotoxic T lymphocyte response to vaccination
    Ulrike Seitzer
    Veterinary Infection Biology and Immunology, Research Center Borstel, Parkallee 22, 23845 Borstel, Germany
    Vaccine 26:G24-8. 2008
    ..Any strain-specificity induced by immunisation is likely to be manifested by CTL. Besides CTLs, CD4+ T-cells also play an important role in protective immunity to T. annulata infection...
  24. ncbi From molecule to diagnostic tool: Theileria annulata surface protein TaSP
    Ulrike Seitzer
    Veterinary Infection Biology and Immunology, Research Center Borstel, Parkallee 22, 23845, Borstel, Germany
    Parasitol Res 101:S217-23. 2007
    ..The ELISA has subsequently been applied for cross-sectional surveys to determine the distribution and prevalence of tropical theileriosis in Sudan...
  25. ncbi Mouse strain specificity of the IgE response to the major allergens of Phleum pratense
    Ulrike Seitzer
    Division of Veterinary Infectiology and Immunology, Research Center Borstel, Borstel, Germany
    Int Arch Allergy Immunol 136:347-55. 2005
    ..pratense allergy...
  26. ncbi Quantitative assessment of immediate cutaneous hypersensitivity in a mouse model exhibiting an IgE response to Timothy grass allergens
    Ulrike Seitzer
    Veterinary Infectiology and Immunology, Department of Immunology and Cell Biology, Research Center Borstel, Borstel, Germany
    Med Sci Monit 9:BR407-12. 2003
    ..Functional read-out parameters include skin reactions and airway constriction. The aim of this study was to establish an improved quantitative assessment of the immediate cutaneous hypersensitivity reaction in a mouse model...
  27. doi Identification of Theileria uilenbergi immunodominant protein for development of an indirect ELISA for diagnosis of ovine theileriosis
    Zhijie Liu
    Division of Veterinary Infection Biology and Immunology, Research Center Borstel, Parkallee 22, D 23845 Borstel, Germany
    Int J Parasitol 40:591-8. 2010
    ..The persistence of the TuIP-specific antibodies lasted more than 100days p.i. These data indicate the usefulness of the TuIP antigen for the development of diagnostic methods and as a potential candidate for vaccine design...
  28. doi Identification and characterization of Theileria annulata heat-shock protein 90 (HSP90) isoforms
    S B Mohammed
    Division of Veterinary Infection Biology and Immunology, Department of Infection, Research Center Borstel, Borstel, Schleswig Holstein, Germany
    Transbound Emerg Dis 60:137-49. 2013
    ..Using flowcytometry, a significant increase (P = 0.028) in cell death (%) was observed in T. annulata-infected cells treated with two different GA concentrations, 0.5 and 1 μm, and incubated for 24, 48 and 72 h...
  29. ncbi Identification, molecular characterization and subcellular localization of a Theileria annulata parasite protein secreted into the host cell cytoplasm
    Ilka Schneider
    Division of Veterinary Infection Biology and Immunology, Department of Immunology and Cell Biology, Research Center Borstel, Parkallee 22, 23845 Borstel, Germany
    Parasitol Res 101:1471-82. 2007
    ..The distribution of TaSE during mitosis makes it a protein to consider as playing a potential role for parasite distribution into daughter host cells...
  30. ncbi Characterization of a polymorphic Theileria annulata surface protein (TaSP) closely related to PIM of Theileria parva: implications for use in diagnostic tests and subunit vaccines
    Leonhard Schnittger
    Forschungszentrum Borstel, Parkallee 22, 23845 Borstel, Germany
    Mol Biochem Parasitol 120:247-56. 2002
    ..The existence of the predicted secretion signal peptide and membrane spanning regions suggest that TaSP is located at the parasite membrane...
  31. ncbi Investigation of MAP kinase activation in Theileria-infected cell lines
    Ulrike Seitzer
    Division of Immunology and Cell Biology, Research Center Borstel, Parkallee 22, 23845 Borstel, Germany
    Ann N Y Acad Sci 1081:473-5. 2006
    ..A study on different Theileria annulata and Theileria parva infected cell lines was performed in order to evaluate the general relevance of the MAP-kinase activation status for Theileria- mediated transformation...
  32. ncbi Phylogeny of sheep and goat Theileria and Babesia parasites
    Leonhard Schnittger
    Department of Immunology and Cell Biology, Research Center Borstel, Parkallee 22, 23845 Borstel, Germany
    Parasitol Res 91:398-406. 2003
    ..2 (China). The recently reported pathogenic sheep/goat Theileria sp. 1 (China) seems to be identical with a Theileria sp. isolated from Japanese serow. Furthermore, our results suggest that T. ovis represents a single species...
  33. ncbi Identification of homologous genes of T. annulata proteins in the genome of Theileria sp. (China)
    Joana P G Miranda
    Instituto de Biologia Experimental e Tecnologica, Oeiras, Portugal
    Ann N Y Acad Sci 1081:468-70. 2006
    ..lestoquardi (Clone-5), with a sequence identity of 100% on the genomic level (Tc Clone-5) but lacking an intron at positions 1894-1928 were identified...
  34. ncbi Identification of potential antigenic proteins of Theileria lestoquardi
    Mohammed Bakheit
    Department of Parasitology, University of Khartoum, Khartoum North, Sudan
    Ann N Y Acad Sci 1081:463-4. 2006
    ..A PCR strategy was used to identify potential antigenic proteins of T. lestoquardi suitable for the development of an ELISA by searching for homologous proteins previously identified in other theilierial parasites to be antigenic...
  35. ncbi Simultaneous detection and differentiation of Theileria and Babesia parasites infecting small ruminants by reverse line blotting
    Leonhard Schnittger
    Department of Immunology and Cell Biology, Research Centre Borstel, Parkallee 22, 23845 Borstel, Germany
    Parasitol Res 92:189-96. 2004
    ....
  36. ncbi Molecular genetic characterization and subcellular localization of a putative Theileria annulata membrane protein
    Ilka Schneider
    Division of Veterinary Infectiology and Immunology, Research Center Borstel, Parkallee 22, 23845 Borstel, Germany
    Parasitol Res 94:405-15. 2004
    ..Using confocal microscopy, the protein was found to be both located in the parasite cytoplasm and to colocalize with a transmembrane protein of the schizonts within infected cells...
  37. ncbi Identification of antigenic proteins of a Theileria species pathogenic for small ruminants in China recognized by antisera of infected animals
    Joana Miranda
    Instituto de Biologia Experimental e Tecnologica, Universidade Nova de Lisboa, Oeiras, Portugal
    Ann N Y Acad Sci 1026:161-4. 2004
    ..The identified parasite antigens and TaSP will be assessed for their suitability for developing diagnostic methods as well as evaluated for their capacity to stimulated host immune competent cells...
  38. ncbi Purification of macroschizonts of a Sudanese isolate of Theileria lestoquardi (T. lestoquardi [Atbara])
    Mohammed A Bakheit
    Department of Parasitology, University of Khartoum, Khartoum North, Sudan
    Ann N Y Acad Sci 1081:453-62. 2006
    ..The cDNA library will be used for screening of antigenic proteins using sera from infected sheep...
  39. ncbi Status of tick distribution in Bangladesh, India and Pakistan
    Srikant Ghosh
    Division of Parasitology, Indian Veterinary Research Institute, Izatnagar, India
    Parasitol Res 101:S207-16. 2007
    ..Among the parasitological problems, the damage caused by TTBDs is considered very high, and the control of TTBDs has been given priority...
  40. ncbi Serological investigation of ovine theileriosis by ELISA in Gannan Tibet Region of Gansu Province in China
    Shuzhen Guo
    Animal Husbandry and Veterinary Medicine Institute of Gannan Tibet Autonomous Region, Hezuo, Gansu, PR China
    Parasitol Res 101:S197-200. 2007
    ....
  41. ncbi A survey of ticks (Acari:Ixodidae) on cattle, sheep and goats in the Dohuk Governorate, Iraq
    Luqman Taib Omer
    Dohuk Research Center, College of Veterinary Medicine, University of Dohuk, Dohuk, Iraq
    Parasitol Res 101:S179-81. 2007
    ..In Eqre, the peaks of infestation occurred after harvesting of cereals in the middle of June until end of July...
  42. ncbi Validation of the indirect TaSP enzyme-linked immunosorbent assay for diagnosis of Theileria annulata infection in cattle
    Dia Eldin A Salih
    Central Veterinary Research Laboratories, Alamarat, P O Box 8067, Khartoum, Sudan
    Parasitol Res 97:302-8. 2005
    ..98 for the cut-off, respectively. There were no cross-reactions with antibodies raised against Babesia spp. It is concluded that the TaSP ELISA is a useful test for the diagnosis of T. annulata infection in cattle under field conditions...
  43. ncbi Identification and characterization of merozoite antigens of a Theileria species highly pathogenic for small ruminants in China
    Joana Miranda
    Instituto de Biologia Experimental e Tecnologica, Universidade Nova de Lisboa, Oeiras, Portugal
    Ann N Y Acad Sci 1081:443-52. 2006
    ..This article represents the first identification and characterization of potential antigenic proteins of Theileria sp. (China) for veterinary purposes...
  44. ncbi Epidemiology of Theileria annulata infection of dairy cattle in the Sudan using molecular techniques
    Awadia M Ali
    University of Khartoum, Khartoum North, Sudan
    Ann N Y Acad Sci 1081:471-2. 2006
    ..This study provides the first epidemiological data regarding T. annulata infection of diary cattle in Sudan using a combination of routine microscopic examination and two molecular techniques, PCR and reverse line blot (RLB)...
  45. ncbi Initiation of translation and cellular localization of Theileria annulata casein kinase IIalpha: implication for its role in host cell transformation
    Reinhild Biermann
    Division of Veterinary Infectiology and Immunology, Research Center Borstel, Parkallee 22, Borstel, Germany
    J Cell Physiol 196:444-53. 2003
    ..On the basis of the above findings it seems highly unlikely that export via the classical pathway of the parasite CKIIalpha is the way in which this protein possibly contributes to host cell transformation...