C Rehfeldt

Summary

Affiliation: Research Institute for the Biology of Farm Animals
Country: Germany

Publications

  1. doi request reprint Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. II--Genetic factors related to animal performance and advances in methodology
    C Rehfeldt
    Research Units Muscle Biology and Growth Molecular Biology, Leibniz Institute for Farm Animals FBN, Wilhelm Stahl Allee, D 18196 Dummerstorf, Germany
    Animal 5:718-30. 2011
  2. pmc Effects of inadequate maternal dietary protein:carbohydrate ratios during pregnancy on offspring immunity in pigs
    Margret Tuchscherer
    Research Unit Behavioural Physiology, Leibniz Institute for Farm Animal Biology FBN, Dummerstorf, Germany
    BMC Vet Res 8:232. 2012
  3. doi request reprint Enhanced sensitivity of skeletal muscle growth in offspring of mice long-term selected for high body mass in response to a maternal high-protein/low-carbohydrate diet during lactation
    Charlotte Rehfeldt
    Research Unit Muscle Biology and Growth, Leibniz Institute for Farm Animal Biology FBN, Wilhelm Stahl Allee 2, 18196, Dummerstorf, Germany
    Eur J Nutr 52:1201-13. 2013
  4. doi request reprint Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. I. Regulation of myogenesis and environmental impact
    C Rehfeldt
    Leibniz Institute for Farm Animals FBN, Wilhelm Stahl Allee 2, D 18196, Dummerstorf, Germany
    Animal 5:703-17. 2011
  5. doi request reprint Limited and excess protein intake of pregnant gilts differently affects body composition and cellularity of skeletal muscle and subcutaneous adipose tissue of newborn and weanling piglets
    Charlotte Rehfeldt
    Research Unit Muscle Biology and Growth, Leibniz Institute for Farm Animal Biology, Wilhelm Stahl Allee 2, Dummerstorf, Germany
    Eur J Nutr 51:151-65. 2012
  6. doi request reprint Effects of limited and excess protein intakes of pregnant gilts on carcass quality and cellular properties of skeletal muscle and subcutaneous adipose tissue in fattening pigs
    C Rehfeldt
    Leibniz Institute for Farm Animal Biology FBN, Research Units of Muscle Biology, Dummerstorf, Germany
    J Anim Sci 90:184-96. 2012
  7. ncbi request reprint Maternal treatment with somatotropin during early gestation affects basic events of myogenesis in pigs
    C Rehfeldt
    Division of Muscle Biology and Growth, Research Institute for the Biology of Farm Animals, Wilhelm Stahl Allee 2, 18196 Dummerstorf, Germany
    Cell Tissue Res 306:429-40. 2001
  8. ncbi request reprint Consequences of birth weight for postnatal growth performance and carcass quality in pigs as related to myogenesis
    C Rehfeldt
    Research Unit Muscle Biology and Growth, Research Institute for the Biology of Farm Animals, D 18196 Dummerstorf, Germany
    J Anim Sci 84:E113-23. 2006
  9. ncbi request reprint Effects of the compact mutant myostatin allele Mstn (Cmpt-dl1Abc) introgressed into a high growth mouse line on skeletal muscle cellularity
    Charlotte Rehfeldt
    Department of Muscle Biology and Growth, Research Institute for the Biology of Farm Animals, Wilhelm Stahl Allee 2, D 18196 Dummerstorf, Germany
    J Muscle Res Cell Motil 26:103-12. 2005
  10. doi request reprint Increased fat mass, decreased myofiber size, and a shift to glycolytic muscle metabolism in adolescent male transgenic mice overexpressing IGFBP-2
    Charlotte Rehfeldt
    Research Divisions Muscle Biology and Growth, Leibniz Institute for Farm Animal Biology, Wilhelm Stahl Allee 2, Dummerstorf, Germany
    Am J Physiol Endocrinol Metab 299:E287-98. 2010

Collaborators

Detail Information

Publications39

  1. doi request reprint Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. II--Genetic factors related to animal performance and advances in methodology
    C Rehfeldt
    Research Units Muscle Biology and Growth Molecular Biology, Leibniz Institute for Farm Animals FBN, Wilhelm Stahl Allee, D 18196 Dummerstorf, Germany
    Animal 5:718-30. 2011
    ..Finally, future research priorities in the field are defined...
  2. pmc Effects of inadequate maternal dietary protein:carbohydrate ratios during pregnancy on offspring immunity in pigs
    Margret Tuchscherer
    Research Unit Behavioural Physiology, Leibniz Institute for Farm Animal Biology FBN, Dummerstorf, Germany
    BMC Vet Res 8:232. 2012
    ....
  3. doi request reprint Enhanced sensitivity of skeletal muscle growth in offspring of mice long-term selected for high body mass in response to a maternal high-protein/low-carbohydrate diet during lactation
    Charlotte Rehfeldt
    Research Unit Muscle Biology and Growth, Leibniz Institute for Farm Animal Biology FBN, Wilhelm Stahl Allee 2, 18196, Dummerstorf, Germany
    Eur J Nutr 52:1201-13. 2013
    ..To investigate the effects of a high-protein/low-carbohydrate diet fed to mice of different genotypes during pregnancy and/or lactation on offspring skeletal muscle growth and metabolism...
  4. doi request reprint Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. I. Regulation of myogenesis and environmental impact
    C Rehfeldt
    Leibniz Institute for Farm Animals FBN, Wilhelm Stahl Allee 2, D 18196, Dummerstorf, Germany
    Animal 5:703-17. 2011
    ..Finally, environmental temperature has been identified as a critical factor for growth and development of skeletal muscle in both fish and poultry...
  5. doi request reprint Limited and excess protein intake of pregnant gilts differently affects body composition and cellularity of skeletal muscle and subcutaneous adipose tissue of newborn and weanling piglets
    Charlotte Rehfeldt
    Research Unit Muscle Biology and Growth, Leibniz Institute for Farm Animal Biology, Wilhelm Stahl Allee 2, Dummerstorf, Germany
    Eur J Nutr 51:151-65. 2012
    ....
  6. doi request reprint Effects of limited and excess protein intakes of pregnant gilts on carcass quality and cellular properties of skeletal muscle and subcutaneous adipose tissue in fattening pigs
    C Rehfeldt
    Leibniz Institute for Farm Animal Biology FBN, Research Units of Muscle Biology, Dummerstorf, Germany
    J Anim Sci 90:184-96. 2012
    ..In contrast, except for a slight transient growth delay, excess dietary protein during gestation seems to have little effect on the fetal programming of postnatal muscle and adipose tissue phenotype of the progeny...
  7. ncbi request reprint Maternal treatment with somatotropin during early gestation affects basic events of myogenesis in pigs
    C Rehfeldt
    Division of Muscle Biology and Growth, Research Institute for the Biology of Farm Animals, Wilhelm Stahl Allee 2, 18196 Dummerstorf, Germany
    Cell Tissue Res 306:429-40. 2001
    ..In conclusion, maternal somatotropin is an influential factor in early pregnancy capable of affecting the basic events of myogenesis...
  8. ncbi request reprint Consequences of birth weight for postnatal growth performance and carcass quality in pigs as related to myogenesis
    C Rehfeldt
    Research Unit Muscle Biology and Growth, Research Institute for the Biology of Farm Animals, D 18196 Dummerstorf, Germany
    J Anim Sci 84:E113-23. 2006
    ..Interactions between maternal nutrition and the somatotropic axis in determining prenatal growth and myogenesis are worthy of further investigation...
  9. ncbi request reprint Effects of the compact mutant myostatin allele Mstn (Cmpt-dl1Abc) introgressed into a high growth mouse line on skeletal muscle cellularity
    Charlotte Rehfeldt
    Department of Muscle Biology and Growth, Research Institute for the Biology of Farm Animals, Wilhelm Stahl Allee 2, D 18196 Dummerstorf, Germany
    J Muscle Res Cell Motil 26:103-12. 2005
    ..However, capillary supply is adversely affected and muscle metabolism shifted towards glycolysis, which could have negative consequences for physical fitness...
  10. doi request reprint Increased fat mass, decreased myofiber size, and a shift to glycolytic muscle metabolism in adolescent male transgenic mice overexpressing IGFBP-2
    Charlotte Rehfeldt
    Research Divisions Muscle Biology and Growth, Leibniz Institute for Farm Animal Biology, Wilhelm Stahl Allee 2, Dummerstorf, Germany
    Am J Physiol Endocrinol Metab 299:E287-98. 2010
    ..The results suggest that IGFBP-2 significantly inhibits postnatal skeletal myofiber growth by decreasing myogenic proliferation and protein accretion and enhances glycolytic muscle metabolism...
  11. ncbi request reprint Effects of exogenous somatotropin during early gestation on maternal performance, fetal growth, and compositional traits in pigs
    C Rehfeldt
    Division of Muscle Biology and Growth, Research Institute for the Biology of Farm Animals, Dummerstorf, Germany
    J Anim Sci 79:1789-99. 2001
    ..It thereby selectively improves the growth conditions for the smaller littermates...
  12. ncbi request reprint Effects of maternal nutrition and porcine growth hormone (pGH) treatment during gestation on endocrine and metabolic factors in sows, fetuses and pigs, skeletal muscle development, and postnatal growth
    Charlotte Rehfeldt
    Division of Muscle Biology and Growth, Research Institute for the Biology of Farm Animals, D 18196 Dummerstorf, Germany
    Domest Anim Endocrinol 27:267-85. 2004
    ....
  13. ncbi request reprint Long-term growth selection of mice changes the intrinsic susceptibility of myogenic cells to apoptosis
    Charlotte Rehfeldt
    Division Muscle Biology and Growth, Genetics and Biometry, Research Institute for the Biology of Farm Animals, D 18196 Dummerstorf, Germany
    J Muscle Res Cell Motil 25:177-85. 2004
    ..Furthermore, the apoptotic response to growth factor withdrawal seems to be largely independent of the stage of myogenic development...
  14. ncbi request reprint Intrinsic properties of muscle satellite cells are changed in response to long-term selection of mice for different growth traits
    C Rehfeldt
    Division of Muscle Biology and Growth, Research Institute for the Biology of Farm Animals, Wilhelm Stahl Allee 2, 18196 Dummerstorf, Germany
    Cell Tissue Res 310:339-48. 2002
    ..0 in the growth and protein lines. In conclusion, long-term selection for growth therefore modifies the intrinsic capability of satellite cells for proliferation and protein metabolism, with changes being dependent on the selection trait...
  15. doi request reprint Effects of L-carnitine supplementation to suckling piglets on carcass and meat quality at market age
    D Lösel
    Research Unit Muscle Biology and Growth, Leibniz Institute for Farm Animal Biology FBN, Wilhelm Stahl Allee 2, 18196 Dummerstorf, Germany
    Animal 7:1191-8. 2013
    ..In conclusion, our hypothesis that early-postnatal carnitine supplementation to piglets of low birth weight permanently increases myofibre number and improves later carcass and meat quality could not be confirmed by this experiment...
  16. ncbi request reprint Administration of recombinant porcine somatotropin (rpST) changes hormone and metabolic status during early pregnancy
    F Schneider
    Division of Reproductive Biology, Research Institute for the Biology of Farm Animals, Wilhelm Stahl Allee 2, 18196 Dummerstorf, Germany
    Domest Anim Endocrinol 23:455-74. 2002
    ..078), and estradiol-17beta (P = 0.087) concentrations tended to be lower in treated animals. These data show that treatment of pregnant gilts with rpST during early gestation mainly impacts metabolic rather than reproductive status...
  17. doi request reprint Limited and excess dietary protein during gestation affects growth and compositional traits in gilts and impairs offspring fetal growth
    C Rehfeldt
    Leibniz Institute for Farm Animal Biology, 18196 Dummerstorf, Germany
    J Anim Sci 89:329-41. 2011
    ....
  18. doi request reprint Effects of low and high protein:carbohydrate ratios in the diet of pregnant gilts on maternal cortisol concentrations and the adrenocortical and sympathoadrenal reactivity in their offspring
    W Otten
    Behavioral Physiology, Leibniz Institute for Farm Animal Biology FBN Dummerstorf, Wilhelm Stahl Allee 2, D 18196 Dummerstorf, Germany
    J Anim Sci 91:2680-92. 2013
    ....
  19. doi request reprint IGF-I- and EGF-dependent DNA synthesis of porcine myoblasts is influenced by the dietary isoflavones genistein and daidzein
    Marcus Mau
    Research Unit Muscle Biology and Growth, Research Institute for the Biology of Farm Animals, Wilhelm Stahl Allee 2, 18196 Dummerstorf, Germany
    Domest Anim Endocrinol 35:281-9. 2008
    ..The results suggest that dietary isoflavones may interact with growth factor-induced stimulation of pig skeletal muscle growth...
  20. ncbi request reprint Effects of treating young boars with a GnRH depot formulation on endocrine functions, testis size, boar taint, carcass composition and muscular structure
    F Schneider
    Research Institute for the Biology of Farm Animals, Dummerstorf, Germany
    Anim Reprod Sci 50:69-80. 1998
    ..39 vs. 50.50%). Overall, these results indicate that the use of this form of GnRH-agonist in a depot formulation offers a new possibility for reducing concentrations of androstenone which is mainly responsible for undesirable boar taint...
  21. doi request reprint Regional differences in micro-structural and biochemical characteristics of growth and metabolism in semitendinosus muscle of 28-day old piglets
    D Lösel
    Leibniz Institute for Farm Animal Biology FBN, Research Unit Muscle Biology and Growth, Wilhelm Stahl Allee 2, D 18196 Dummerstorf, Germany
    Meat Sci 87:19-25. 2011
    ....
  22. doi request reprint Moderate high or low maternal protein diets change gene expression but not the phenotype of skeletal muscle from porcine fetuses
    C Kalbe
    Institute of Muscle Biology and Growth, Leibniz Institute for Farm Animal Biology FBN, 18196 Dummerstorf, Germany Electronic address
    Domest Anim Endocrinol 58:63-75. 2017
    ..Moreover, we suggest that the modified gene expression in fetal skeletal muscle can be viewed as the origin of developmental muscular plasticity involved in the concept of fetal programming...
  23. doi request reprint L-Carnitine supplementation during suckling intensifies the early postnatal skeletal myofiber formation in piglets of low birth weight
    D Lösel
    Research Unit Muscle Biology and Growth, Research Institute for the Biology of Farm Animals, Dummerstorf, Germany
    J Anim Sci 87:2216-26. 2009
    ....
  24. doi request reprint Effects of leptin and adiponectin on the growth of porcine myoblasts are associated with changes in p44/42 MAPK signaling
    K Will
    Institute for Muscle Biology and Growth, Leibniz Institute for Farm Animal Biology FBN, Wilhelm Stahl Allee 2, 18196 Dummerstorf, Germany
    Domest Anim Endocrinol 45:196-205. 2013
    ..05). In conclusion, adiponectin and leptin may adversely affect the growth of porcine myoblasts, which is related to p44/42 MAPK signaling and associated with changes in ligand receptor gene expression. ..
  25. ncbi request reprint Establishment and conditions for growth and differentiation of a myoblast cell line derived from the semimembranosus muscle of newborn piglets
    Marcus Mau
    Research Institute for the Biology of Farm Animals, Research Unit Muscle Biology and Growth, Wilhelm Stahl Allee 2, Dummerstorf, Germany
    In Vitro Cell Dev Biol Anim 44:1-5. 2008
    ..By establishing this culture system, we provide an advanced and appropriate in vitro model to study porcine skeletal muscle cell growth and differentiation including the responses to various bioactive compounds...
  26. doi request reprint Dose-dependent effects of genistein and daidzein on protein metabolism in porcine myotube cultures
    Charlotte Rehfeldt
    Research Unit Muscle Biology and Growth and Research Unit Genetics and Biometry, Research Institute for the Biology of Farm Animals, Dummerstorf, Germany
    J Agric Food Chem 57:852-7. 2009
    ..05). The results suggest that both genistein and daidzein affect protein metabolism in a dose-dependent manner and that estrogenic actions may play a role in decreasing protein degradation in porcine skeletal muscle...
  27. doi request reprint Developmental changes and the impact of isoflavones on mRNA expression of IGF-I receptor, EGF receptor and related growth factors in porcine skeletal muscle cell cultures
    Claudia Kalbe
    Research Institute for the Biology of Farm Animals, Research Unit Muscle Biology and Growth, Wilhelm Stahl Allee 2, Dummerstorf, Germany
    Growth Horm IGF Res 18:424-33. 2008
    ....
  28. ncbi request reprint Effects of dietary isoflavones on proliferation and DNA integrity of myoblasts derived from newborn piglets
    Marcus Mau
    Muscle Biology and Growth Research Unit, Research Institute for the Biology of Farm Animals, Dummerstorf, D 18196, Germany
    Pediatr Res 63:39-45. 2008
    ..Conclusively, isoflavones at concentrations of greater than 1 muM act as inhibitors of porcine skeletal muscle cell proliferation...
  29. ncbi request reprint Simulation of giant fibre development in biopsy samples from pig longissimus muscle
    A Schubert-Schoppmeyer
    Research Institute for the Biology of Farm Animals, Research Unit Muscle Biology and Growth, Wilhelm Stahl Allee 2, Dummerstorf 18196, Germany
    Meat Sci 80:1297-303. 2008
    ..87 for carcass samples. "Simulated" giant fibres exhibited ultrastructural changes in plasma membrane, myofibrils, mitochondria, and sarcoplasmatic reticulum as shown previously for giant fibres in carcass samples...
  30. ncbi request reprint Growth performance, carcass characteristics and bioavailability of isoflavones in pigs fed soy bean based diets
    Gerda Kuhn
    Research Institute for the Biology of Farm Animals FBN, Dummerstorf, Germany
    Arch Anim Nutr 58:265-76. 2004
    ..The results confirm the expected differences in the bioavailability of soy isoflavones, yet, there were no significant differences in performance of pigs fed either soy bean meal or soy protein concentrate...
  31. ncbi request reprint Evidence for estrogen receptor alpha and beta expression in skeletal muscle of pigs
    Claudia Kalbe
    Research Institute for Biology of Farm Animals FBN, Muscle Biology and Growth Research Unit, Wilhelm Stahl Allee 2, 18196 Dummerstorf, Germany
    Histochem Cell Biol 127:95-107. 2007
    ..The porcine SM satellite cell culture provides a suitable in vitro model to investigate estrogenic effects on pig skeletal muscle...
  32. ncbi request reprint A second look at the influence of birth weight on carcass and meat quality in pigs
    C Rehfeldt
    Research Unit Muscle Biology and Growth, Research Institute for the Biology of Farm Animals, 18196 Dummerstorf, Germany
    Meat Sci 78:170-5. 2008
    ..The results suggest that the most desirable carcass composition is obtained with HW pigs, whereas optimum technological pork quality, except for IMF, is achieved with MW pigs...
  33. ncbi request reprint Effects of dietary daidzein supplementation of pregnant sows on carcass and meat quality and skeletal muscle cellularity of the progeny
    C Rehfeldt
    Research Institute for the Biology of Farm Animals, Research Unit Muscle Biology and Growth, Wilhelm Stahl Allee 2, D 18196 Dummerstorf, Germany
    Meat Sci 75:103-11. 2007
    ..06) by maternal daidzein feeding. The results suggest that supplemental daidzein in the maternal diet during late gestation marginally affects meat quality and skeletal muscle cellularity of the progeny...
  34. ncbi request reprint Gonadotropin release in periovulatory heifers after GnRH analogs measured by two types of immunoassays
    F Schneider
    Unit of Reproductive Biology, Research Institute for the Biology of Farm Animals, Dummerstorf, Germany
    Exp Clin Endocrinol Diabetes 110:235-44. 2002
    ....
  35. ncbi request reprint Marker-assisted introgression of the Compact mutant myostatin allele MstnCmpt-dl1Abc into a mouse line with extreme growth effects on body composition and muscularity
    Lutz Bunger
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3JT, UK
    Genet Res 84:161-73. 2004
    ..This line, when congenic, will be a useful resource in gene expression studies and for finding modifying genes...
  36. ncbi request reprint [Aspects of prenatal development of muscle and adipose tissue: principles, regulation, and influence of maternal nutrition]
    Claudia Kalbe
    Forschungsbereich Muskelbiologie und Wachstum, Forschungsinstitut für die Biologie landwirtschaftlicher Nutztiere, Dummerstorf
    Berl Munch Tierarztl Wochenschr 118:509-20. 2005
    ....
  37. ncbi request reprint Muscle energy metabolism: structural and functional features in different types of porcine striated muscles
    Korinna Huber
    Department of Physiology, School of Veterinary Medicine, Bischofsholer Damm 15 102, 30173 Hannover, Germany
    J Muscle Res Cell Motil 28:249-58. 2007
    ..GHR mRNA expression was also highest in longissimus muscle indicating that an enhanced effect of growth hormone, which is described to be diabetogenic, could be involved in the lower insulin sensitivity of glycolytic muscles...
  38. ncbi request reprint In response to Point:Counterpoint: "Satellite cell addition is/is not obligatory for skeletal muscle hypertrophy"
    Charlotte Rehfeldt
    J Appl Physiol 103:1104. 2007
  39. ncbi request reprint Susceptibility to apoptosis in different murine muscle cell lines
    Matthias Wittstock
    Department of Neurology, University of Rostock, Gehlsheimner Strasse 20, D 18147 Rostock, Germany
    J Muscle Res Cell Motil 24:521-6. 2003
    ..Moreover, long-term selection for growth decreases the basic frequency of apoptosis of muscle satellite cells, but increases their susceptibility to apoptosis induction...