W G Damen

Summary

Affiliation: University of Cologne
Country: Germany

Publications

  1. pmc Expression patterns of hairy, even-skipped, and runt in the spider Cupiennius salei imply that these genes were segmentation genes in a basal arthropod
    W G Damen
    Department of Evolution Genetics, Institut fur Genetik, Universitat zu Koln, Weyertal 121, D 50931 Cologne, Germany
    Proc Natl Acad Sci U S A 97:4515-9. 2000
  2. ncbi Arthropod segmentation: why centipedes are odd
    Wim G M Damen
    Institute for Genetics, Department for Evolutionary Genetics, University of Cologne, Weyertal 121, D 50931 Köln, Germany
    Curr Biol 14:R557-9. 2004
  3. ncbi Pair rule gene orthologs in spider segmentation
    Wim G M Damen
    Department for Evolutionary Genetics, Institute for Genetics, University of Cologne, Zülpicher Str 47, D 50674 Köln, Germany
    Evol Dev 7:618-28. 2005
  4. ncbi Evolutionary conservation and divergence of the segmentation process in arthropods
    Wim G M Damen
    Institut für Genetik der Universität zu Köln, Zülpicher Str 47, 50674 Koln, Germany
    Dev Dyn 236:1379-91. 2007
  5. ncbi fushi tarazu: a Hox gene changes its role
    Wim G M Damen
    Institut fur Genetik, Universitat zu Koln, Weyertal 121, D 50931 Köln, Germany
    Bioessays 24:992-5. 2002
  6. ncbi Parasegmental organization of the spider embryo implies that the parasegment is an evolutionary conserved entity in arthropod embryogenesis
    Wim G M Damen
    Institut fur Genetik, Universitat zu Koln, Weyertal 121, D 50931 Köln, Germany
    Development 129:1239-50. 2002
  7. ncbi Diverse adaptations of an ancestral gill: a common evolutionary origin for wings, breathing organs, and spinnerets
    Wim G M Damen
    Institute for Genetics, University of Cologne, Weyertal 121, D 50931, Koln, Germany
    Curr Biol 12:1711-6. 2002
  8. ncbi Diversification of nubbin expression patterns in arthropods: data from an additional spider species, Cupiennius salei
    Nikola Michael Prpic
    Institute for Genetics, University of Cologne, Weyertal 121, 50931 Cologne, Germany
    Evol Dev 7:276-9. 2005
  9. ncbi Double-stranded RNA interference in the spider Cupiennius salei: the role of Distal-less is evolutionarily conserved in arthropod appendage formation
    M Schoppmeier
    , Evolutionary Genetics, , Weyertal 121, 50931 Cologne, Germany
    Dev Genes Evol 211:76-82. 2001
  10. ncbi Gene expression in spider appendages reveals reversal of exd/hth spatial specificity, altered leg gap gene dynamics, and suggests divergent distal morphogen signaling
    Nikola Michael Prpic
    Institut fur Genetik, Universitat zu Koln, Weyertal 121, D 50931 Köln, Germany
    Dev Biol 264:119-40. 2003

Detail Information

Publications27

  1. pmc Expression patterns of hairy, even-skipped, and runt in the spider Cupiennius salei imply that these genes were segmentation genes in a basal arthropod
    W G Damen
    Department of Evolution Genetics, Institut fur Genetik, Universitat zu Koln, Weyertal 121, D 50931 Cologne, Germany
    Proc Natl Acad Sci U S A 97:4515-9. 2000
    ..These data imply that the involvement of hairy, even-skipped, and runt in arthropod segmentation is an ancestral character for arthropods and is not restricted to a particular group of insects...
  2. ncbi Arthropod segmentation: why centipedes are odd
    Wim G M Damen
    Institute for Genetics, Department for Evolutionary Genetics, University of Cologne, Weyertal 121, D 50931 Köln, Germany
    Curr Biol 14:R557-9. 2004
    ..Is this an oddity of centipedes, or might it mean that double segmental pair-rule patterning dates back to the Ur-arthropod?..
  3. ncbi Pair rule gene orthologs in spider segmentation
    Wim G M Damen
    Department for Evolutionary Genetics, Institute for Genetics, University of Cologne, Zülpicher Str 47, D 50674 Köln, Germany
    Evol Dev 7:618-28. 2005
    ..The segmentation function of fushi tarazu thus appears to be a newly acquired role of the gene in the lineage of the mandibulate arthropods...
  4. ncbi Evolutionary conservation and divergence of the segmentation process in arthropods
    Wim G M Damen
    Institut für Genetik der Universität zu Köln, Zülpicher Str 47, 50674 Koln, Germany
    Dev Dyn 236:1379-91. 2007
    ....
  5. ncbi fushi tarazu: a Hox gene changes its role
    Wim G M Damen
    Institut fur Genetik, Universitat zu Koln, Weyertal 121, D 50931 Köln, Germany
    Bioessays 24:992-5. 2002
    ..Recent data of Mouchel-Vielh et al., and Hughes and Kaufman on ftz homologues in a crustacean and a myriapod, respectively, shed new light onto the evolution of this gene...
  6. ncbi Parasegmental organization of the spider embryo implies that the parasegment is an evolutionary conserved entity in arthropod embryogenesis
    Wim G M Damen
    Institut fur Genetik, Universitat zu Koln, Weyertal 121, D 50931 Köln, Germany
    Development 129:1239-50. 2002
    ..The lack of by engrailed and wingless/Wnt-defined boundaries in other segmented phyla does not support a common origin of segmentation...
  7. ncbi Diverse adaptations of an ancestral gill: a common evolutionary origin for wings, breathing organs, and spinnerets
    Wim G M Damen
    Institute for Genetics, University of Cologne, Weyertal 121, D 50931, Koln, Germany
    Curr Biol 12:1711-6. 2002
    ....
  8. ncbi Diversification of nubbin expression patterns in arthropods: data from an additional spider species, Cupiennius salei
    Nikola Michael Prpic
    Institute for Genetics, University of Cologne, Weyertal 121, 50931 Cologne, Germany
    Evol Dev 7:276-9. 2005
  9. ncbi Double-stranded RNA interference in the spider Cupiennius salei: the role of Distal-less is evolutionarily conserved in arthropod appendage formation
    M Schoppmeier
    , Evolutionary Genetics, , Weyertal 121, 50931 Cologne, Germany
    Dev Genes Evol 211:76-82. 2001
    ..Our data show that the expression of Dll in the appendages is conserved among arthropods, and furthermore that the role of Dll is evolutionarily conserved in the formation of segmental appendages in arthropods...
  10. ncbi Gene expression in spider appendages reveals reversal of exd/hth spatial specificity, altered leg gap gene dynamics, and suggests divergent distal morphogen signaling
    Nikola Michael Prpic
    Institut fur Genetik, Universitat zu Koln, Weyertal 121, D 50931 Köln, Germany
    Dev Biol 264:119-40. 2003
    ..Thus, the leg developmental system exhibits a propensity to evolutionary change, which probably forms the basis for the impressive diversity of arthropod leg morphologies...
  11. ncbi Evolution of dorsal-ventral axis formation in arthropod appendages: H15 and optomotor-blind/bifid-type T-box genes in the millipede Glomeris marginata (Myriapoda: Diplopoda)
    Nikola Michael Prpic
    Department for Evolutionary Genetics, Institute for Genetics, University of Cologne, Weyertal 121, 50931 Koln, Germany
    Evol Dev 7:51-7. 2005
    ..In addition, no ventral expression domain is present in the maxilla, mandible, and antenna. Because of this, the role of H15 in the determination of ventral fate remains unclear...
  12. ncbi Expression of dachshund in wild-type and Distal-less mutant Tribolium corroborates serial homologies in insect appendages
    N M Prpic
    Institut fur Genetik, Universitat zu Koln, Weyertal 121, 50931 Cologne, Germany
    Dev Genes Evol 211:467-77. 2001
    ..Based on Tc'dac expression in wild-type and mutant embryos, we demonstrate serial homology of the complete mandible with the coxa of the thoracic legs, which affirms the gnathobasic nature of the insect mandible...
  13. doi hunchback functions as a segmentation gene in the spider Achaearanea tepidariorum
    Evelyn E Schwager
    Institute for Genetics, Evolutionary Genetics, University of Cologne, Zulpicher Strasse 47, D 50674 Köln, Germany
    Curr Biol 19:1333-40. 2009
    ..In addition, hb is a major regulator of Hox genes and it has been suggested that this is the ancestral role of hb in insects or perhaps even arthropods. To date, however, hb function has been analyzed only in insects...
  14. ncbi Expression patterns of leg genes in the mouthparts of the spider Cupiennius salei (Chelicerata: Arachnida)
    Nikola Michael Prpic
    Institut fur Genetik, Universitat zu Koln, Weyertal 121, 50931, Cologne, Germany
    Dev Genes Evol 214:296-302. 2004
    ..g. antenna, chelicera) may result from the loss of such antagonistic domains...
  15. doi The T-box genes H15 and optomotor-blind in the spiders Cupiennius salei, Tegenaria atrica and Achaearanea tepidariorum and the dorsoventral axis of arthropod appendages
    Ralf Janssen
    Institut fur Genetik, Universitat zu Koln, Abteilung für Evolutionsgenetik, Zülpicher Str 47, 50674 Koln, Germany
    Evol Dev 10:143-54. 2008
    ..Our results emphasize the importance of a broad taxon sampling in comparative studies...
  16. doi Diverged and conserved aspects of heart formation in a spider
    Ralf Janssen
    Institute for Genetics, Evolutionary Genetics, University of Cologne, Zulpicher Strasse 47, 50674 Koln, Germany
    Evol Dev 10:155-65. 2008
    ..In contrast to the posterior heart tissue, these cells do not express the other heart genes. The spider heart thus is composed of two distinct populations of cells...
  17. doi Notch-mediated segmentation of the appendages is a molecular phylotypic trait of the arthropods
    Nikola Michael Prpic
    Institut fur Genetik, Universitat zu Koln, Zülpicher Str 47, 50674 Koln, Germany
    Dev Biol 326:262-71. 2009
    ..Notch-mediated limb segmentation is thus a molecular phylotypic trait of the arthropods...
  18. doi Wnt8 is required for growth-zone establishment and development of opisthosomal segments in a spider
    Alistair P McGregor
    Institute for Genetics, Evolutionary Genetics, University of Cologne, Zülpicher Strasse 47 D 50674, Koln, Germany
    Curr Biol 18:1619-23. 2008
    ..Furthermore, we propose that Wnt8, caudal, and Delta/Notch may be parts of an ancient genetic regulatory network that could have been required for posterior specification in the last common ancestor of protostomes and deuterostomes...
  19. doi Cupiennius salei and Achaearanea tepidariorum: Spider models for investigating evolution and development
    Alistair P McGregor
    Institute for Genetics, Evolutionary Genetics, University of Cologne, Koln, Germany
    Bioessays 30:487-98. 2008
    ..We suggest that further comparisons between these two spiders and other chelicerates will prove useful for understanding the evolution of development in metazoans...
  20. ncbi Suppressor of Hairless and Presenilin phenotypes imply involvement of canonical Notch-signalling in segmentation of the spider Cupiennius salei
    Michael Schoppmeier
    Institute for Genetics, Department for Evolutionary Genetics, University of Cologne, Weyertal 121, D 50931 Köln, Germany
    Dev Biol 280:211-24. 2005
    ....
  21. ncbi Gene expression suggests decoupled dorsal and ventral segmentation in the millipede Glomeris marginata (Myriapoda: Diplopoda)
    Ralf Janssen
    Department for Evolutionary Genetics, Institute for Genetics, University of Cologne, D 50931 Köln, Germany
    Dev Biol 268:89-104. 2004
    ..g., Glomeris) and is suggestive also for derived, ring-forming diplopods (e.g., Juliformia)...
  22. ncbi Involvement of Notch and Delta genes in spider segmentation
    Angelika Stollewerk
    Institute of Genetics, Evolutionary Genetics, University of Cologne, Koln, Germany
    Nature 423:863-5. 2003
    ..Our data indicate that formation of the segments in arthropods and vertebrates may have shared a genetic programme in a common ancestor and that parts of this programme have been lost in particular descendant lineages...
  23. ncbi The ten Hox genes of the millipede Glomeris marginata
    Ralf Janssen
    Institute for Genetics, Department for Evolutionary Genetics, University of Cologne, Zulpicher Strasse 47, D 50674 Köln, Germany
    Dev Genes Evol 216:451-65. 2006
    ....
  24. ncbi A homolog of the hydrolase Notum is expressed during segmentation and appendage formation in the Central American hunting spider Cupiennius salei
    Nikola Michael Prpic
    Institut für Genetik der Universität zu Köln, Weyertal 121, 50931, Koln, Germany
    Naturwissenschaften 92:246-9. 2005
    ..In the appendages, Notum is expressed in ventral mesodermal cells, directly adjacent to the Wingless expressing ectodermal cells. This could indicate a role for the mesoderm in regulating morphogen gradient formation in the ectoderm...
  25. pmc Dynamic gene expression is required for anterior regionalization in a spider
    Matthias Pechmann
    Department of Evolutionary Genetics, Institute for Genetics, University of Cologne, Zulpicher Strasse 47, 50674 Koln, Germany
    Proc Natl Acad Sci U S A 106:1468-72. 2009
    ....
  26. ncbi Expression of Pax group III genes suggests a single-segmental periodicity for opisthosomal segment patterning in the spider Cupiennius salei
    Michael Schoppmeier
    Institute for Genetics, Department for Evolutionary Genetics, University of Cologne, Weyertal 121, D 50931 Köln, Germany
    Evol Dev 7:160-9. 2005
    ..The segment-polarity genes are required to define the segment borders of the embryo at the germ-band stage, the arthropod phylotypic stage. Pair-rule gene orthologs act more upstream and may display more variation in their action...
  27. ncbi Cell death during germ band inversion, dorsal closure, and nervous system development in the spider Cupiennius salei
    Nikola Michael Prpic
    Universitat zu Koln, Institut fur Genetik, Germany
    Dev Dyn 234:222-8. 2005
    ..Our data show that germ band inversion involves cell death to facilitate the ventral splitting of the germ band, as well as the epithelial fusion during dorsal closure...