Manuela Lindemeyer

Summary

Affiliation: University of Leipzig
Country: Germany

Publications

  1. pmc Homology-based annotation of non-coding RNAs in the genomes of Schistosoma mansoni and Schistosoma japonicum
    Claudia S Copeland
    Bioinformatics Group, Department of Computer Science and Interdisciplinary Center for Bioinformatics, University of Leipzig, Härtelstrasse 16 18, D 04107 Leipzig, Germany
    BMC Genomics 10:464. 2009
  2. doi request reprint Evolution of 7SK RNA and its protein partners in metazoa
    Manja Marz
    Bioinformatics Group, Department of Computer Science, and Interdisciplinary Center for Bioinformatics, University of Leipzig, Leipzig, Germany
    Mol Biol Evol 26:2821-30. 2009
  3. doi request reprint Evolution of spliceosomal snRNA genes in metazoan animals
    Manuela Marz
    Bioinformatics Group, Department of Computer Science, University of Leipzig, Härtelstrasse 16 18, 04107 Leipzig, Germany
    J Mol Evol 67:594-607. 2008
  4. ncbi request reprint Comparative analysis of eukaryotic U3 snoRNA
    Manja Marz
    Bioinformatics Group, Department of Computer Science, and Interdisciplinary Center for Bioinformatics, University of Leipzig, Leipzig, Germany
    RNA Biol 6:503-7. 2009
  5. ncbi request reprint Temperature-dependent structural variability of RNAs: spliced leader RNAs and their evolutionary history
    Manja Marz
    Bioinformatics Group, Department of Computer Science, University of Leipzig, Härtelstrasse 16 18, D 04107 Leipzig, Germany
    J Bioinform Comput Biol 8:1-17. 2010
  6. pmc Non-coding RNA annotation of the genome of Trichoplax adhaerens
    Jana Hertel
    Bioinformatics Group, Department of Computer Science, Interdisciplinary Center for Bioinformatics, University of Leipzig, D 04107 Leipzig, Germany
    Nucleic Acids Res 37:1602-15. 2009
  7. pmc The expansion of the metazoan microRNA repertoire
    Jana Hertel
    Bioinformatics Group, Department of Computer Science, University of Leipzig, Härtelstrasse 16 18, D 04107 Leipzig, Germany
    BMC Genomics 7:25. 2006
  8. ncbi request reprint U7 snRNAs: a computational survey
    Manja Marz
    Bioinformatics Group, Department of Computer Science, University of Leipzig, Leipzig D 04107, Germany
    Genomics Proteomics Bioinformatics 5:187-95. 2007
  9. pmc Conserved introns reveal novel transcripts in Drosophila melanogaster
    Michael Hiller
    Bioinformatics Group, Albert Ludwigs University Freiburg, 79110 Freiburg, Germany
    Genome Res 19:1289-300. 2009
  10. doi request reprint RNA interactions
    Manja Marz
    Department of Computer Science, University of Leipzig, Leipzig, Germany
    Adv Exp Med Biol 722:20-38. 2011

Detail Information

Publications10

  1. pmc Homology-based annotation of non-coding RNAs in the genomes of Schistosoma mansoni and Schistosoma japonicum
    Claudia S Copeland
    Bioinformatics Group, Department of Computer Science and Interdisciplinary Center for Bioinformatics, University of Leipzig, Härtelstrasse 16 18, D 04107 Leipzig, Germany
    BMC Genomics 10:464. 2009
    ..The genome-wide annotation of ncRNAs is a non-trivial task unless well-annotated genomes of closely related species are already available...
  2. doi request reprint Evolution of 7SK RNA and its protein partners in metazoa
    Manja Marz
    Bioinformatics Group, Department of Computer Science, and Interdisciplinary Center for Bioinformatics, University of Leipzig, Leipzig, Germany
    Mol Biol Evol 26:2821-30. 2009
    ..Furthermore, we derive an improved secondary structure model of 7SK RNA, which shows that the structure is quite well-conserved across animal phyla despite the extreme divergence at sequence level...
  3. doi request reprint Evolution of spliceosomal snRNA genes in metazoan animals
    Manuela Marz
    Bioinformatics Group, Department of Computer Science, University of Leipzig, Härtelstrasse 16 18, 04107 Leipzig, Germany
    J Mol Evol 67:594-607. 2008
    ..An analysis of genomic context of snRNAs reveals that they behave like mobile elements, exhibiting very little syntenic conservation...
  4. ncbi request reprint Comparative analysis of eukaryotic U3 snoRNA
    Manja Marz
    Bioinformatics Group, Department of Computer Science, and Interdisciplinary Center for Bioinformatics, University of Leipzig, Leipzig, Germany
    RNA Biol 6:503-7. 2009
    ..Many fungal U3 genes, in addition, contain introns. U3 promoters are snRNA-like but show substantial variations even between related species...
  5. ncbi request reprint Temperature-dependent structural variability of RNAs: spliced leader RNAs and their evolutionary history
    Manja Marz
    Bioinformatics Group, Department of Computer Science, University of Leipzig, Härtelstrasse 16 18, D 04107 Leipzig, Germany
    J Bioinform Comput Biol 8:1-17. 2010
    ..Supplementary Table is available at http://www.worldscinet.com/jbcb/...
  6. pmc Non-coding RNA annotation of the genome of Trichoplax adhaerens
    Jana Hertel
    Bioinformatics Group, Department of Computer Science, Interdisciplinary Center for Bioinformatics, University of Leipzig, D 04107 Leipzig, Germany
    Nucleic Acids Res 37:1602-15. 2009
    ..We did not find any microRNA candidates homologous to known eumetazoan sequences. Interestingly, most ncRNAs, including the pol-III transcripts, appear as single-copy genes or with very small copy numbers in the Trichoplax genome...
  7. pmc The expansion of the metazoan microRNA repertoire
    Jana Hertel
    Bioinformatics Group, Department of Computer Science, University of Leipzig, Härtelstrasse 16 18, D 04107 Leipzig, Germany
    BMC Genomics 7:25. 2006
    ..This allows us to reliably identify microRNA clusters that are derived from a common transcript...
  8. ncbi request reprint U7 snRNAs: a computational survey
    Manja Marz
    Bioinformatics Group, Department of Computer Science, University of Leipzig, Leipzig D 04107, Germany
    Genomics Proteomics Bioinformatics 5:187-95. 2007
    ..These results cast doubt on putative U7 homologs in even more distant organisms that are reported in the most recent release of the Rfam database...
  9. pmc Conserved introns reveal novel transcripts in Drosophila melanogaster
    Michael Hiller
    Bioinformatics Group, Albert Ludwigs University Freiburg, 79110 Freiburg, Germany
    Genome Res 19:1289-300. 2009
    ..As conserved introns indicate both purifying selection on the exon-intron structure and conserved expression of the transcript in related species, the novel mlncRNAs are good candidates for functional transcripts...
  10. doi request reprint RNA interactions
    Manja Marz
    Department of Computer Science, University of Leipzig, Leipzig, Germany
    Adv Exp Med Biol 722:20-38. 2011
    ..Conservation of both sequence and structure thus this can give indications of the functioning of the diversity of ncRNAs...