Edda Töpfer-Petersen

Summary

Affiliation: University of Veterinary Medicine
Country: Germany

Publications

  1. ncbi request reprint Role of quinine-sensitive ion channels in volume regulation in boar and bull spermatozoa
    A M Petrunkina
    Institute for Reproductive Medicine, School of Veterinary Medicine Hannover, Bünteweg 15, 30559 Hannover, Germany
    Reproduction 122:327-36. 2001
  2. ncbi request reprint Heterogeneous osmotic behaviour in boar sperm populations and its relevance for detection of changes in plasma membrane
    A M Petrunkina
    Institute for Reproductive Medicine, School of Veterinary Medicine, Hannover, Germany
    Reprod Fertil Dev 12:297-305. 2000
  3. ncbi request reprint Seeking mathematical strategies in sperm function analysis: between scylla and charybdis?
    A M Petrunkina
    Institute for Reproductive Medicine, School of Veterinary Medicine Hannover, Hannover, Germany
    Reprod Domest Anim 38:125-33. 2003
  4. ncbi request reprint Specific order in the appearance of protein tyrosine phosphorylation patterns is functionally coordinated with dog sperm hyperactivation and capacitation
    Anna M Petrunkina
    Institute for Reproductive Medicine, School of Veterinary Medicine Hannover, Hannover, Germany
    J Androl 24:423-37. 2003
  5. ncbi request reprint Role of potassium channels, the sodium-potassium pump and the cytoskeleton in the control of dog sperm volume
    A M Petrunkina
    Institute for Reproductive Medicine, School of Veterinary Medicine Hannover, Bünteweg 15, 30559, Hannover, Germany
    Theriogenology 61:35-54. 2004
  6. ncbi request reprint Role of volume-stimulated osmolyte and anion channels in volume regulation by mammalian sperm
    A M Petrunkina
    Institute of Reproductive Medicine, University of Veterinary Medicine Hannover, Foundation, Bünteweg 15, 30559 Hannover, Germany
    Mol Hum Reprod 10:815-23. 2004
  7. ncbi request reprint Functional significance of responsiveness to capacitating conditions in boar spermatozoa
    Anna M Petrunkina
    Institute for Reproductive Medicine, University of Veterinary Medicine Hannover, Foundation, Bünteweg 15, 30559 Hannover, Germany
    Theriogenology 64:1766-82. 2005
  8. ncbi request reprint Regulatory and necrotic volume increase in boar spermatozoa
    A M Petrunkina
    Institute for Reproductive Medicine, School of Veterinary Medicine Hannover, Foundation, Hannover, Germany
    J Cell Physiol 204:508-21. 2005
  9. ncbi request reprint Molecular characterization of the equine AEG1 locus
    Alexander Giese
    Institute of Animal Breeding and Genetics, School of Veterinary Medicine Hannover, Bunteweg 17p, 30559 Hannover, Germany
    Gene 292:65-72. 2002
  10. ncbi request reprint Detection of cooling-induced membrane changes in the response of boar sperm to capacitating conditions
    Anna M Petrunkina
    Institute for Reproductive Medicine, University of Veterinary Medicine Hannover, Foundation, Bünteweg 15, 30559 Hannover, Germany
    Theriogenology 63:2278-99. 2005

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Role of quinine-sensitive ion channels in volume regulation in boar and bull spermatozoa
    A M Petrunkina
    Institute for Reproductive Medicine, School of Veterinary Medicine Hannover, Bünteweg 15, 30559 Hannover, Germany
    Reproduction 122:327-36. 2001
    ....
  2. ncbi request reprint Heterogeneous osmotic behaviour in boar sperm populations and its relevance for detection of changes in plasma membrane
    A M Petrunkina
    Institute for Reproductive Medicine, School of Veterinary Medicine, Hannover, Germany
    Reprod Fertil Dev 12:297-305. 2000
    ....
  3. ncbi request reprint Seeking mathematical strategies in sperm function analysis: between scylla and charybdis?
    A M Petrunkina
    Institute for Reproductive Medicine, School of Veterinary Medicine Hannover, Hannover, Germany
    Reprod Domest Anim 38:125-33. 2003
    ....
  4. ncbi request reprint Specific order in the appearance of protein tyrosine phosphorylation patterns is functionally coordinated with dog sperm hyperactivation and capacitation
    Anna M Petrunkina
    Institute for Reproductive Medicine, School of Veterinary Medicine Hannover, Hannover, Germany
    J Androl 24:423-37. 2003
    ..Phosphorylation kinetics of sperm proteins are potentially useful for diagnostic purposes to characterize the response of individual males to fertilizing conditions...
  5. ncbi request reprint Role of potassium channels, the sodium-potassium pump and the cytoskeleton in the control of dog sperm volume
    A M Petrunkina
    Institute for Reproductive Medicine, School of Veterinary Medicine Hannover, Bünteweg 15, 30559, Hannover, Germany
    Theriogenology 61:35-54. 2004
    ..Under isotonic conditions at 25 degrees C, a considerable proportion of the sperm population is already swollen; this swelling varies between individual males and appears to be due to lowered cytoskeletal and potassium channel activity...
  6. ncbi request reprint Role of volume-stimulated osmolyte and anion channels in volume regulation by mammalian sperm
    A M Petrunkina
    Institute of Reproductive Medicine, University of Veterinary Medicine Hannover, Foundation, Bünteweg 15, 30559 Hannover, Germany
    Mol Hum Reprod 10:815-23. 2004
    ..Our observations provide direct evidence that a chloride channel (possibly ClC-3) is involved in the process of volume regulation in mammalian sperm...
  7. ncbi request reprint Functional significance of responsiveness to capacitating conditions in boar spermatozoa
    Anna M Petrunkina
    Institute for Reproductive Medicine, University of Veterinary Medicine Hannover, Foundation, Bünteweg 15, 30559 Hannover, Germany
    Theriogenology 64:1766-82. 2005
    ..It can be concluded that the combination of sperm responsiveness parameters applied here is a suitable tool for the evaluation of sperm function...
  8. ncbi request reprint Regulatory and necrotic volume increase in boar spermatozoa
    A M Petrunkina
    Institute for Reproductive Medicine, School of Veterinary Medicine Hannover, Foundation, Hannover, Germany
    J Cell Physiol 204:508-21. 2005
    ..The ability to regulate volume after exposure to hypertonic conditions is important for sperm functionality and can have practical applications in spermatological diagnostics and cryopreservation...
  9. ncbi request reprint Molecular characterization of the equine AEG1 locus
    Alexander Giese
    Institute of Animal Breeding and Genetics, School of Veterinary Medicine Hannover, Bunteweg 17p, 30559 Hannover, Germany
    Gene 292:65-72. 2002
    ..Finally, sequence comparisons revealed that the intronless equine PGK2 gene for the testis-specific phosphoglycerate kinase is located approximately 39 kb downstream of AEG1...
  10. ncbi request reprint Detection of cooling-induced membrane changes in the response of boar sperm to capacitating conditions
    Anna M Petrunkina
    Institute for Reproductive Medicine, University of Veterinary Medicine Hannover, Foundation, Bünteweg 15, 30559 Hannover, Germany
    Theriogenology 63:2278-99. 2005
    ..It can be concluded that the simultaneous use of the sperm membrane responsiveness and kinetic parameters is a sensitive tool for the detection of storage-related membrane changes in boar semen...
  11. ncbi request reprint Molecular characterization of the equine testis-specific protein 1 (TPX1) and acidic epididymal glycoprotein 2 (AEG2) genes encoding members of the cysteine-rich secretory protein (CRISP) family
    Alexander Giese
    Institute of Animal Breeding and Genetics, School of Veterinary Medicine Hannover, Bunteweg 17p, 30559 Hannover, Germany
    Gene 299:101-9. 2002
    ..Comparative genome analysis between horse, human, and mouse indicates that all three CRISP genes are clustered on one chromosomal location, which shows conserved synteny between these species...
  12. ncbi request reprint Function of the mammalian oviductal sperm reservoir
    Edda Töpfer-Petersen
    Institute of Reproductive Medicine, School of Veterinary Medicine Hannover, D 30559 Hannover, Germany
    J Exp Zool 292:210-5. 2002
    ..Spermadhesins, a new class of animal lectins and the major secretory products of the porcine seminal vesicle, associate with the sperm surface at ejaculation and are candidate molecules for the receptors of the epithelial carbohydrates...
  13. ncbi request reprint Functional significance of the cell volume for detecting sperm membrane changes and predicting freezability in dog semen
    Anna M Petrunkina
    Institute for Reproductive Medicine, School of Veterinary Medicine Hannover Foundation, Bünteweg 15, 30559 Hannover, Germany
    Reproduction 128:829-42. 2004
    ..The individual variability in response to osmotic stress or to calcium ionophore treatment appears to reflect the subtle differences in the sperm membrane functionality which are crucial for the prediction of cryopreservability...
  14. ncbi request reprint The role of stallion seminal proteins in fertilisation
    Edda Töpfer-Petersen
    Institute of Reproductive Medicine, University of Veterinary Medicine Hannover, Bünteweg 15, 30559 Hannover, Germany
    Anim Reprod Sci 89:159-70. 2005
    ..The major proteins of equine seminal plasma have been isolated and characterised regarding their expression along the male genital tract, protein structure and their functions...
  15. ncbi request reprint Structural and molecular characterization of equine sperm-binding fibronectin-II module proteins
    Mahnaz Ekhlasi-Hundrieser
    Institute of Reproductive Medicine, School of Veterinary Medicine Hannover, Foundation, Hannover, Germany
    Mol Reprod Dev 70:45-57. 2005
    ..Enhanced fluorescence intensity after ejaculation point to an increased number of molecules bound to the sperm surface. The function of these proteins is discussed in regard to their structure-function relationships...
  16. ncbi request reprint Fibronectin type II-module proteins in the bovine genital tract and their putative role in cell volume control during sperm maturation
    Evrim Sahin
    Clinic for Pigs and Small Ruminants, University of Veterinary Medicine Hannover, Foundation, Unit of Reproductive Medicine of the Clinics, Bünteweg 15, Hannover 30559, Germany
    Reprod Fertil Dev 21:479-88. 2009
    ..While the protein had no effect on cauda spermatozoa, it caused caput spermatozoa to swell more in response to hypotonic stress, similarly to untreated cauda spermatozoa...
  17. ncbi request reprint Carbohydrate-based interactions of oviductal sperm reservoir formation-studies in the pig
    Andrea Wagner
    Institute of Reproductive Medicine, School of Veterinary Medicine Hannover, Germany
    Mol Reprod Dev 61:249-57. 2002
    ....
  18. ncbi request reprint Dynamic quantification of the tyrosine phosphorylation of the sperm surface proteins during capacitation
    Erik Piehler
    Institute for Reproductive Biology, School of Veterinary Medicine Hannover Foundation, Hannover, Germany
    Cytometry A 69:1062-70. 2006
    ..A calcium influx seems to be required for the completion of tyrosine phosphorylation in some species; however, the exact temporal coordination between these processes is still poorly understood...
  19. ncbi request reprint Expression of spermadhesin genes in porcine male and female reproductive tracts
    Mahnaz Ekhlasi-Hundrieser
    Institute of Reproductive Medicine, School of Veterinary Medicine Hannover, Germany
    Mol Reprod Dev 61:32-41. 2002
    ..The role of spermadhesins in relation to their expression is discussed...
  20. ncbi request reprint Evolution of the spermadhesin gene family
    Bianca Haase
    Institute of Animal Breeding and Genetics, School of Veterinary Medicine Hannover, Bünteweg 17 p, 30559 Hannover, Germany
    Gene 352:20-9. 2005
    ..Interestingly, the pattern of divergence does not correlate with the position of the exons. Evolutionary analyses suggest that the pattern of diversity is shaped by ancestral variation, recombination, and new mutations...
  21. ncbi request reprint Spermadhesin AQN1 is a candidate receptor molecule involved in the formation of the oviductal sperm reservoir in the pig
    Mahnaz Ekhlasi-Hundrieser
    Institute of Reproductive Medicine, School of Veterinary Medicine Hannover, Foundation, 30559 Hannover, Germany
    Biol Reprod 73:536-45. 2005
    ..These results demonstrate that the sperm lectin AQN1 fulfils the criteria for an oviduct receptor in the pig and may play a role in the formation of the oviductal sperm reservoir...
  22. doi request reprint Chromatin-unstable boar spermatozoa have little chance of reaching oocytes in vivo
    Florencia Ardón
    Unit for Reproductive Medicine of Clinics for Pigs and Small Ruminants, University of Veterinary Medicine Hannover, Bünteweg 15, D 30559 Hannover, Germany
    Reproduction 135:461-70. 2008
    ..We conclude that in vivo the likelihood that sperm with unstable chromatin will reach the egg and fertilize it is low...
  23. ncbi request reprint Control of bull sperm cell volume during epididymal maturation
    Evrim Sahin
    Clinic for Pigs and Small Ruminants, University of Veterinary Medicine Hannover, Foundation, Unit of Reproductive Medicine of the Clinics, Bünteweg 15, Hannover 30559, Germany
    Reprod Fertil Dev 21:469-78. 2009
    ....
  24. ncbi request reprint Analysis of N-linked glycans of porcine zona pellucida glycoprotein ZPA by MALDI-TOF MS: a contribution to understanding zona pellucida structure
    Dorothee von Witzendorff
    Institute for Reproductive Medicine, School of Veterinary Medicine Hannover, Foundation, Bünteweg 15, 30559 Hannover, Germany Shimadzu Deutschland GmbH, Albert Hahn Str 6 10, 47269 Duisburg, Germany
    Glycobiology 15:475-88. 2005
    ..N-glycosidase F treatment of the isolated glycopeptides and MS analysis resulted in the identification of the corresponding deglycosylated peptides...
  25. doi request reprint Point mutations abolishing the mannose-binding capability of boar spermadhesin AQN-1
    Mahnaz Ekhlasi-Hundrieser
    Department of Reproductive Biology, University of Veterinary Medicine Hannover, Foundation, Bünteweg 2, 30559 Hannover, Germany
    Biochim Biophys Acta 1784:856-62. 2008
    ..This indicates that different spermadhesin molecules have evolved non-equivalent carbohydrate-binding capabilities, which may underlie their distinct patterns of biological activities...
  26. ncbi request reprint Sperm-binding fibronectin type II-module proteins are genetically linked and functionally related
    Mahnaz Ekhlasi-Hundrieser
    Department of Reproductive Biology, University of Veterinary Medicine Hannover, Bünteweg 2, 30559 Hannover, Germany
    Gene 392:253-65. 2007
    ..However, differences in their regionalized expression patterns along the male genital tract as well as in association sites on the sperm surface suggested a species-specific sequential order in sperm binding...
  27. doi request reprint Glycobiology of fertilization in the pig
    Edda Töpfer-Petersen
    Department of Reproductive Biology, University of Veterinary Medicine Hannover, Hannover, Germany
    Int J Dev Biol 52:717-36. 2008
    ..Furthermore, some preliminary data supporting the hypothesis that the zona pellucida has to undergo a maturation process during oocyte development are presented...