Yunhao Gong

Summary

Publications

  1. ncbi request reprint Preclinical evaluation of docusate as protective agent from herpes simplex viruses
    Y Gong
    Viridae Clinical Sciences, Inc, 1134 Burrard Street, Vancouver, British Columbia, V6Z 1Y8, Canada
    Antiviral Res 52:25-32. 2001
  2. pmc Evidence that the RNAseH activity of the duck hepatitis B virus is unable to act on exogenous substrates
    Y Gong
    Department of Molecular Microbiology and Immunology, St Louis University School of Medicine, 1402 South Grand Blvd, St Louis, MO 63104, USA
    BMC Microbiol 1:12. 2001
  3. ncbi request reprint Evidence of dual sites of action of dendrimers: SPL-2999 inhibits both virus entry and late stages of herpes simplex virus replication
    Yunhao Gong
    Viridae Clinical Sciences, Inc, 1134 Burrard Street, Vancouver, BC, Canada V6Z 1Y8
    Antiviral Res 55:319-29. 2002
  4. ncbi request reprint The synergistic effects of betulin with acyclovir against herpes simplex viruses
    Yunhao Gong
    Viridae Clinical Sciences Inc, 1134 Burrard Street, Vancouver, BC, Canada V6Z 1Y8
    Antiviral Res 64:127-30. 2004
  5. pmc Identification of an essential molecular contact point on the duck hepatitis B virus reverse transcriptase
    Feng Cao
    Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, 1402 S Grand Blvd, St Louis, MO 63104, USA
    J Virol 79:10164-70. 2005

Detail Information

Publications5

  1. ncbi request reprint Preclinical evaluation of docusate as protective agent from herpes simplex viruses
    Y Gong
    Viridae Clinical Sciences, Inc, 1134 Burrard Street, Vancouver, British Columbia, V6Z 1Y8, Canada
    Antiviral Res 52:25-32. 2001
    ..Docusate pretreatment of cells was associated with a 45% reduction in infectivity of those cells, despite a triple washing procedure. Once infected, an approximate 30% plaque reduction was observed with treatment...
  2. pmc Evidence that the RNAseH activity of the duck hepatitis B virus is unable to act on exogenous substrates
    Y Gong
    Department of Molecular Microbiology and Immunology, St Louis University School of Medicine, 1402 South Grand Blvd, St Louis, MO 63104, USA
    BMC Microbiol 1:12. 2001
    ..The mechanism of this template commitment is unknown. Here we provide evidence that the RNAseH activity of duck hepatitis B virus reverse transcriptase may also be unable to act on exogenous substrates...
  3. ncbi request reprint Evidence of dual sites of action of dendrimers: SPL-2999 inhibits both virus entry and late stages of herpes simplex virus replication
    Yunhao Gong
    Viridae Clinical Sciences, Inc, 1134 Burrard Street, Vancouver, BC, Canada V6Z 1Y8
    Antiviral Res 55:319-29. 2002
    ..Our data indicate that SPL-2999 is a potent inhibitor of both HSV-1 and -2 with the potential for further development as either a topical microbicide or a therapeutic agent...
  4. ncbi request reprint The synergistic effects of betulin with acyclovir against herpes simplex viruses
    Yunhao Gong
    Viridae Clinical Sciences Inc, 1134 Burrard Street, Vancouver, BC, Canada V6Z 1Y8
    Antiviral Res 64:127-30. 2004
    ..At the concentrations lower than these, additive effect was found. Synergistic antiviral effects were also found against HSV-2 at higher concentrations than for HSV-1, i.e. 0.45 microg/ml of ACV combined with 8.4 microg/ml of betulin...
  5. pmc Identification of an essential molecular contact point on the duck hepatitis B virus reverse transcriptase
    Feng Cao
    Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, 1402 S Grand Blvd, St Louis, MO 63104, USA
    J Virol 79:10164-70. 2005
    ..Therefore, small-molecule ligands that compete for binding to T3 with its natural ligand could form a novel class of antiviral drugs...