Dimitrios Tziafas

Summary

Affiliation: Aristotle University of Thessaloniki
Location: Thessaloniki, Greece
Summary:
Biology of dentin-pulp complex.
Regenerative therapeutic approaches in endodontology
Toxicity of restorative dental materials
Grants:
1993-1995. BIOMED 1 (Rf PL 920419). Commission of the European Communities. Role line manager. “Toxicity of Root Canal Sealers”.

1993-1998. PENED 91 (ED91No549) and . PENED 95 (ED95No636) General Secreteriat of Research & Technology in Greece. Role Scientific Manager. “Autoinduction of
Dentinogenesis and induction of reparative dentinogenesis”.

1996-2000. COST (B8) “Odontogenesis” . Commission of the European Communities. Role National Representative in Managment Committee. Chairperson of the 3rd Working
group.

1999-2001. PENED 99 (ED95No643) General Secreteriat of Research & Technology in Greece. Role Scientific Manager. “TGF-beta1 in Vital Pulp Therapy”.

2003-2005 EPEAEK 2003 Heraklitos 21475. Commission of the European Communities and Ministry of Education in Greece. Role Scientific Manager. “The role of TGFbeta 1 in
transdentinal stimulation of tertiary dentinogenesis”.

2003-2007 COST (B8) “Oral Facial Development and repair”. Commission of the European Communities. Role National Representative in Managment Committee.

2005-2008 EPEAEK 2005 PYTHAGORAS 80843. Commission of the European Communities and Ministry of Education in Greece. Role Scientific Manager. “Development of biologically active treatment modalities in sites of endodontic tissue trauma”.

Publications

  1. ncbi request reprint Inability of calcium hydroxide to induce reparative dentinogenesis at non-peripheral sites of dog dental pulp
    D Tziafas
    Department of Dental Pathology and Therapeutics, Aristotle University of Thessaloniki, Greece
    Eur J Oral Sci 104:623-6. 1996
  2. doi request reprint Transdentinal stimulation of tertiary dentine formation and intratubular mineralization by growth factors
    M Kalyva
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Int Endod J 43:382-92. 2010
  3. doi request reprint Differentiation potential of dental papilla, dental pulp, and apical papilla progenitor cells
    Dimitrios Tziafas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    J Endod 36:781-9. 2010
  4. doi request reprint Effect of simulated pulpal microcirculation on intrapulpal temperature changes following application of heat on tooth surfaces
    K Kodonas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Int Endod J 42:247-52. 2009
  5. ncbi request reprint Pulpal responses after application of current adhesive systems to deep cavities
    Eugenia Koliniotou-Koumpia
    Department of Operative Dentistry, School of Dentistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
    Clin Oral Investig 11:313-20. 2007
  6. ncbi request reprint Irreversible but not reversible pulpitis is associated with up-regulation of tumour necrosis factor-alpha gene expression in human pulp
    A B Kokkas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Int Endod J 40:198-203. 2007
  7. ncbi request reprint Effects of a new antibacterial adhesive on the repair capacity of the pulp-dentine complex in infected teeth
    D Tziafas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Int Endod J 40:58-66. 2007
  8. ncbi request reprint Pulpal responses following direct pulp capping of healthy dog teeth with dentine adhesive systems
    E Koliniotou-Koumpia
    Department of Operative Dentistry, School of Dentistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
    J Dent 33:639-47. 2005
  9. ncbi request reprint Compound maxillary odontoma in a young German shepherd dog
    S Papadimitriou
    Department of Clinical Sciences Clinic of Surgery, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, 11 St Voutyra Street, 546 27 Thessaloniki, Greece
    J Small Anim Pract 46:146-50. 2005
  10. ncbi request reprint The future role of a molecular approach to pulp-dentinal regeneration
    D Tziafas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Caries Res 38:314-20. 2004

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Inability of calcium hydroxide to induce reparative dentinogenesis at non-peripheral sites of dog dental pulp
    D Tziafas
    Department of Dental Pathology and Therapeutics, Aristotle University of Thessaloniki, Greece
    Eur J Oral Sci 104:623-6. 1996
    ..In response to the centrally implanted cements, only atubular hard tissue with lining fibroblast-like cells was deposited...
  2. doi request reprint Transdentinal stimulation of tertiary dentine formation and intratubular mineralization by growth factors
    M Kalyva
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Int Endod J 43:382-92. 2010
    ..To evaluate the effects of recombinant growth factors on tertiary dentine formation and intratubular mineralization after their application on deep dentinal cavities in dog's teeth...
  3. doi request reprint Differentiation potential of dental papilla, dental pulp, and apical papilla progenitor cells
    Dimitrios Tziafas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    J Endod 36:781-9. 2010
    ..Regenerative endodontic procedures use the differentiation potential of embryonic and adult pulp progenitor cell populations to reconstitute dental structures...
  4. doi request reprint Effect of simulated pulpal microcirculation on intrapulpal temperature changes following application of heat on tooth surfaces
    K Kodonas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Int Endod J 42:247-52. 2009
    ..To evaluate ex vivo whether a simulated pulpal microcirculation inside a pulp chamber influenced intrapulpal temperature rise following application of heat on tooth surfaces...
  5. ncbi request reprint Pulpal responses after application of current adhesive systems to deep cavities
    Eugenia Koliniotou-Koumpia
    Department of Operative Dentistry, School of Dentistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
    Clin Oral Investig 11:313-20. 2007
    ....
  6. ncbi request reprint Irreversible but not reversible pulpitis is associated with up-regulation of tumour necrosis factor-alpha gene expression in human pulp
    A B Kokkas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Int Endod J 40:198-203. 2007
    ....
  7. ncbi request reprint Effects of a new antibacterial adhesive on the repair capacity of the pulp-dentine complex in infected teeth
    D Tziafas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Int Endod J 40:58-66. 2007
    ....
  8. ncbi request reprint Pulpal responses following direct pulp capping of healthy dog teeth with dentine adhesive systems
    E Koliniotou-Koumpia
    Department of Operative Dentistry, School of Dentistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
    J Dent 33:639-47. 2005
    ..The aim of the present study was to evaluate the pulpal responses following direct pulp capping of mechanically exposed teeth with new dentine adhesive systems, in the preclinical model of dog teeth...
  9. ncbi request reprint Compound maxillary odontoma in a young German shepherd dog
    S Papadimitriou
    Department of Clinical Sciences Clinic of Surgery, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, 11 St Voutyra Street, 546 27 Thessaloniki, Greece
    J Small Anim Pract 46:146-50. 2005
    ..Morphology and structure of the denticles were also confirmed by scanning electron microscopy. A compound odontoma was diagnosed. One year after surgery, the dog was free of clinical signs...
  10. ncbi request reprint The future role of a molecular approach to pulp-dentinal regeneration
    D Tziafas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Caries Res 38:314-20. 2004
    ..Promising biologically active substances should be subjected to careful evaluation in well-designed preclinical investigations as well as in long-term clinical trials before their introduction in clinical practice...
  11. ncbi request reprint Short-term periradicular tissue response to mineral trioxide aggregate (MTA) as root-end filling material
    N Economides
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Greece
    Int Endod J 36:44-8. 2003
    ..The aim of the present study was to evaluate the short-term response of periradicular tissues to MTA when used as a root-end filling material in ideal tissue conditions...
  12. ncbi request reprint Dentin regeneration in vital pulp therapy: design principles
    D Tziafas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, 54006 Thessaloniki, Greece
    Adv Dent Res 15:96-100. 2001
    ....
  13. ncbi request reprint Experimental dentin-based approaches to tissue regeneration in vital pulp therapy
    D Tziafas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, 54006 Thessaloniki, Greece
    Connect Tissue Res 43:391-5. 2002
    ..Furthermore, it seems that the traumatized mature pulp maintains the ability to grow, while a calcifying potential could be expressed by this growing part of the pulp core...
  14. ncbi request reprint The dentinogenic effect of mineral trioxide aggregate (MTA) in short-term capping experiments
    D Tziafas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Greece
    Int Endod J 35:245-54. 2002
    ..The objective of the present experiment was to study the early pulpal cell response and the onset of reparative dentine formation after capping application of MTA in mechanically exposed pulps...
  15. ncbi request reprint A case report of a compound odontoma causing delayed eruption of a central maxillary incisor: clinical and microscopic evaluation
    A Veis
    Department of Endodontology, Dental School, Aristotle University of Thessaloniki, Thessaloniki, Greece
    J Endod 26:477-9. 2000
    ..The most homogeneous tissue was dentin. The removal of the odontoma was followed by a rapid eruption of the impacted central incisor...
  16. ncbi request reprint Designing new treatment strategies in vital pulp therapy
    D Tziafas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Greece
    J Dent 28:77-92. 2000
    ....
  17. ncbi request reprint Formation of crystals on the surface of calcium hydroxide-containing materials in vitro
    D Tziafas
    Department of Endodontology, Dental School, Aristotle University Thessaloniki, Greece
    J Endod 25:539-42. 1999
    ..This modification might play an important role in the regulation of cell adhesion and the initiation of new matrix synthesis...
  18. ncbi request reprint Effects of recombinant basic fibroblast growth factor, insulin-like growth factor-II and transforming growth factor-beta 1 on dog dental pulp cells in vivo
    D Tziafas
    Department of Endodontology, School of Dentistry, Greece
    Arch Oral Biol 43:431-44. 1998
    ..Implantation of bFGF and IGF-II did not result in reparative dentine formation, but did stimulate osteotypical matrix deposition at a distance from the implants...
  19. ncbi request reprint Role of exogenous TGF-beta in induction of reparative dentinogenesis in vivo
    D Tziafas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Greece
    Eur J Oral Sci 106:192-6. 1998
    ....
  20. ncbi request reprint Induction of odontoblast-like cell differentiation in dog dental pulps after in vivo implantation of dentine matrix components
    D Tziafas
    Department of Dental Pathology and Therapeutics, Dental School, Aristotle University of Thessaloniki, Greece
    Arch Oral Biol 40:883-93. 1995
    ....
  21. doi request reprint Dentinogenic Specificity in the Preclinical Evaluation of Vital Pulp Treatment Strategies: A Critical Review.
    Dimitrios Tziafas
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece
    Dent J (Basel) 3:133-156. 2015
    ....