I Spiliopoulou

Summary

Affiliation: University of Patras
Country: Greece

Publications

  1. ncbi request reprint erm(C) is the predominant genetic determinant for the expression of resistance to macrolides among methicillin-resistant Staphylococcus aureus clinical isolates in Greece
    I Spiliopoulou
    Department of Microbiology, School of Medicine, University of Patras, Rion 26500, Patras, Greece
    J Antimicrob Chemother 53:814-7. 2004
  2. ncbi request reprint Application of molecular typing methods to characterize nosocomial coagulase-negative staphylococci collected in a Greek hospital during a three-year period (1998-2000)
    I Spiliopoulou
    Molecular Genetics Laboratory, Instituto de Tecnologia Quimica e Biologica, Universidade Nova de Lisboa ITQB UNL, Oeiras, Portugal
    Microb Drug Resist 9:273-82. 2003
  3. ncbi request reprint Detection of mecA, mecR1 and mecI genes among clinical isolates of methicillin-resistant staphylococci by combined polymerase chain reactions
    E Petinaki
    Department of Microbiology, School of Medicine, University of Patras, 26500 Rion, Patras, Greece
    J Antimicrob Chemother 47:297-304. 2001
  4. doi request reprint Community-associated Staphylococcus aureus infections and nasal carriage among children: molecular microbial data and clinical characteristics
    G Sdougkos
    Department of Orthopaedics, Karamandaneion Children s Hospital, Patras, Greece
    Clin Microbiol Infect 14:995-1001. 2008
  5. ncbi request reprint Clonal dissemination of mupirocin-resistant staphylococci in Greek hospitals
    E Petinaki
    Department of Microbiology, School of Medicine, University of Thessalia, Papakyriazi 22, Larissa
    J Antimicrob Chemother 53:105-8. 2004
  6. ncbi request reprint The emergence of glycopeptide-resistant Enterococcus faecium in a university hospital in southwestern Greece
    F Kolonitsiou
    Department of Microbiology, University of Patras School of Medicine, Patras, Greece
    Chemotherapy 50:245-9. 2004
  7. ncbi request reprint Clonality of slime-producing methicillin-resistant coagulase-negative staphylococci disseminated in the neonatal intensive care unit of a university hospital
    A Foka
    Department of Microbiology, School of Medicine, University of Patras, Patras, Greece
    Clin Microbiol Infect 12:1230-3. 2006
  8. pmc Two international methicillin-resistant Staphylococcus aureus clones endemic in a university hospital in Patras, Greece
    M Aires de Sousa
    Laboratorio de Genetica Molecular, Instituto de Tecnologia Química e Biológica da Universidade Nova de Lisboa, Oeiras, Portugal
    J Clin Microbiol 41:2027-32. 2003
  9. ncbi request reprint Comparison of two commercial methods with PCR restriction fragment length polymorphism of the tuf gene in the identification of coagulase-negative staphylococci
    K Alexopoulou
    Department of Microbiology, School of Medicine, University of Patras, Patras, Greece
    Lett Appl Microbiol 43:450-4. 2006
  10. ncbi request reprint The combined effect of surface chemistry and flow conditions on Staphylococcus epidermidis adhesion and ica operon expression
    A Foka
    Laboratory of Biomechanics and Biomedical Engineering, Department of Mechanical Engineering and Aeronautics, University of Patras, Rion, Patras, Greece
    Eur Cell Mater 24:386-402. 2012

Collaborators

  • H de Lencastre
  • K S Filos
  • S Alexiou-Daniel
  • L Zerva
  • E Petinaki
  • E D Anastassiou
  • M Papadimitriou-Olivgeris
  • A Foka
  • G Dimitracopoulos
  • F Kolonitsiou
  • E Drougka
  • V Chini
  • M Marangos
  • F Fligou
  • M Christofidou
  • A N Maniatis
  • C Bartzavali
  • V Dodou
  • M Maniati
  • N Giormezis
  • E Jelastopulu
  • A Liakopoulos
  • G Sdougkos
  • H Malamou-Lada
  • E Fegou
  • F Kontos
  • M Karanika
  • K Koutsileou
  • A G Doudoulakakis
  • A Pratti
  • S F Assimakopoulos
  • E Lebessi
  • A Spiliopoulou
  • A Vogiatzi
  • G Dimitriou
  • V Stamouli
  • Y F Missirlis
  • I Neonakis
  • E Malli
  • D Bakola
  • D A Papanastasiou
  • G Christodoulou
  • M Katsikogianni
  • K Alexopoulou
  • M Sevdali
  • Ch Koutsia-Carouzou
  • M Paragioudaki
  • A Spyropoulou
  • N Sioulas
  • A Zotou
  • V Karamouzos
  • S Vamvakopoulou
  • A Michos
  • D Bouras
  • M Kazantzi
  • A Vantarakis
  • M Aires de Sousa
  • S Filippidou
  • M Tsolia
  • S Sarrou
  • A Charisiadou
  • P Manolopoulou
  • A Makri
  • D Logothetis
  • D Dimitropoulou
  • G Panos
  • A Doudoulakakis
  • T Panagea
  • N Bereksi
  • S Levidiotou
  • G Zambardi
  • J Hey
  • A Arvaniti
  • T Makatsoris
  • M N Marangos
  • M G Katsikogianni
  • S Tzifas
  • I Giannakopoulos
  • S Fouzas
  • S Mantagos
  • D E Anastassiou
  • I Christodoulidi
  • S Grapsa
  • E Giannitsioti
  • F Frantzidou
  • S Kartali-Ktenidou
  • E Stamatakis
  • M Anifantaki
  • C Koutsia-Carouzou
  • E Alepopoulou

Detail Information

Publications43

  1. ncbi request reprint erm(C) is the predominant genetic determinant for the expression of resistance to macrolides among methicillin-resistant Staphylococcus aureus clinical isolates in Greece
    I Spiliopoulou
    Department of Microbiology, School of Medicine, University of Patras, Rion 26500, Patras, Greece
    J Antimicrob Chemother 53:814-7. 2004
    ..Macrolide, lincosamide and streptogramin type B (MLS(B)) resistance was determined in Staphylococcus aureus clinical isolates from two University Hospitals...
  2. ncbi request reprint Application of molecular typing methods to characterize nosocomial coagulase-negative staphylococci collected in a Greek hospital during a three-year period (1998-2000)
    I Spiliopoulou
    Molecular Genetics Laboratory, Instituto de Tecnologia Quimica e Biologica, Universidade Nova de Lisboa ITQB UNL, Oeiras, Portugal
    Microb Drug Resist 9:273-82. 2003
    ....
  3. ncbi request reprint Detection of mecA, mecR1 and mecI genes among clinical isolates of methicillin-resistant staphylococci by combined polymerase chain reactions
    E Petinaki
    Department of Microbiology, School of Medicine, University of Patras, 26500 Rion, Patras, Greece
    J Antimicrob Chemother 47:297-304. 2001
    ..Among methicillin-resistant S. aureus, a genetically heterogeneous population was identified, with several alterations and deletions of mec genes...
  4. doi request reprint Community-associated Staphylococcus aureus infections and nasal carriage among children: molecular microbial data and clinical characteristics
    G Sdougkos
    Department of Orthopaedics, Karamandaneion Children s Hospital, Patras, Greece
    Clin Microbiol Infect 14:995-1001. 2008
    ..The present study demonstrates that infections due to PVL-positive CA-MRSA spread easily among children, and SSTIs can lead to invasive infections. Nasal colonization may be an additional factor contributing to the emergence of CA-MRSA...
  5. ncbi request reprint Clonal dissemination of mupirocin-resistant staphylococci in Greek hospitals
    E Petinaki
    Department of Microbiology, School of Medicine, University of Thessalia, Papakyriazi 22, Larissa
    J Antimicrob Chemother 53:105-8. 2004
    ..To determine the rates of mupirocin resistance in staphylococci during a 4 year period (1999-2002) in Greece...
  6. ncbi request reprint The emergence of glycopeptide-resistant Enterococcus faecium in a university hospital in southwestern Greece
    F Kolonitsiou
    Department of Microbiology, University of Patras School of Medicine, Patras, Greece
    Chemotherapy 50:245-9. 2004
    ..Enterococci and especially glycopeptide-resistant strains (GRE) are widely distributed in the hospital environment, by acquiring resistance determinants and virulence factors...
  7. ncbi request reprint Clonality of slime-producing methicillin-resistant coagulase-negative staphylococci disseminated in the neonatal intensive care unit of a university hospital
    A Foka
    Department of Microbiology, School of Medicine, University of Patras, Patras, Greece
    Clin Microbiol Infect 12:1230-3. 2006
    ..The entire ica cluster was detected in three of 15 slime-negative isolates. One major and two minor slime-positive, multiresistant MR-CNS clones had disseminated among hospitalised pre-term neonates...
  8. pmc Two international methicillin-resistant Staphylococcus aureus clones endemic in a university hospital in Patras, Greece
    M Aires de Sousa
    Laboratorio de Genetica Molecular, Instituto de Tecnologia Química e Biológica da Universidade Nova de Lisboa, Oeiras, Portugal
    J Clin Microbiol 41:2027-32. 2003
    ..Both clones seem to be widespread in Greece as well. A novel MRSA clone is also described and is characterized by a new MLST type (ST80) associated with SCCmec type IV and with the presence of Panton-Valentine leukocidin genes...
  9. ncbi request reprint Comparison of two commercial methods with PCR restriction fragment length polymorphism of the tuf gene in the identification of coagulase-negative staphylococci
    K Alexopoulou
    Department of Microbiology, School of Medicine, University of Patras, Patras, Greece
    Lett Appl Microbiol 43:450-4. 2006
    ..Two commercial methods for the identification of coagulase-negative staphylococci (CNS) were compared with the restriction fragment length polymorphism (RFLP) of the amplified tuf gene, which served as the reference method...
  10. ncbi request reprint The combined effect of surface chemistry and flow conditions on Staphylococcus epidermidis adhesion and ica operon expression
    A Foka
    Laboratory of Biomechanics and Biomedical Engineering, Department of Mechanical Engineering and Aeronautics, University of Patras, Rion, Patras, Greece
    Eur Cell Mater 24:386-402. 2012
    ..This indicates that analysis of gene expression not only can greatly refine our knowledge of bacteria-material interactions, but also yield novel biomarkers for potential use in biocompatibility assessment...
  11. ncbi request reprint Methicillin-resistant Staphylococcus aureus producing Panton-Valentine leukocidin as a cause of acute osteomyelitis in children
    G Sdougkos
    Department of Orthopaedics, Karamandaneion Children s Hospital, Patras, Greece
    Clin Microbiol Infect 13:651-4. 2007
    ....
  12. ncbi request reprint Absolute and relative real-time PCR in the quantification of tst gene expression among methicillin-resistant Staphylococcus aureus: evaluation by two mathematical models
    V Chini
    Department of Microbiology, School of Medicine, University of Patras, Patras, Greece
    Lett Appl Microbiol 45:479-84. 2007
    ....
  13. ncbi request reprint Decreased affinity of PBP3 to methicillin in a clinical isolate of Staphylococcus epidermidis with borderline resistance to methicillin and free of the mecA gene
    E Petinaki
    Department of Microbiology, School of Medicine, University of Patras, Greece
    Microb Drug Resist 7:297-300. 2001
    ..0 microg/ml) in an isolate free of the mecA gene is due to the decreased binding capacity of PBP3...
  14. ncbi request reprint Spread of Staphylococcus aureus clinical isolates carrying Panton-Valentine leukocidin genes during a 3-year period in Greece
    V Chini
    Department of Microbiology, School of Medicine, University of Patras, Patras, Greece
    Clin Microbiol Infect 12:29-34. 2006
    ..Thus, a unique clone of PVL-positive MRSA has spread in both the community and the hospital setting in Greece, and has replaced older clonal types...
  15. doi request reprint The first case of Staphylococcus aureus ST398 causing bacteremia in an immunocompromised patient in Greece
    E Drougka
    Department of Microbiology, School of Medicine, National Reference Laboratory for Staphylococcal Infections, University of Patras, Greece
    Indian J Med Microbiol 30:232-6. 2012
    ..The patient recovered after daptomycin therapy. This is the first report that documents the emergence of ST398 in Greece...
  16. ncbi request reprint Comparison of the manual Mycobacteria Growth Indicator tube and the Etest with the method of proportion for susceptibility testing of Mycobacterium tuberculosis
    E Fegou
    Department of Microbiology, University of Patras, School of Medicine, Patras, Greece
    Chemotherapy 52:174-7. 2006
    ..Clinical microbiology laboratories should provide reliable results on susceptibility testing of Mycobacterium tuberculosis to different agents...
  17. ncbi request reprint Reduced susceptibility to quinupristin/dalfopristin in Enterococcus faecium in Greece without prior exposure to the agent
    M Karanika
    Department of Microbiology, Medical School, University of Thessalia, Papakyriazi 22, Larissa 41222, Greece
    Int J Antimicrob Agents 31:55-7. 2008
    ..The high percentage of Q/D-intermediate-resistant E. faecium in Greece was not associated with prior consumption of the agent or with the veterinary use of virginiamycin...
  18. doi request reprint In vitro activity of daptomycin against Gram-positive cocci: the first multicentre study in Greece
    E Malli
    Department of Microbiology, University Hospital of Larissa, Larissa, Greece
    Int J Antimicrob Agents 32:525-8. 2008
    ..For all tested organism groups, resistance to daptomycin was not associated with glycopeptide resistance...
  19. ncbi request reprint Intravenous catheter infections associated with bacteraemia: a 2-year study in a university hospital
    M Paragioudaki
    Department of Microbiology, School of Medicine, University of Patras, 26500, Greece
    Clin Microbiol Infect 10:431-5. 2004
    ..Resistance to glycopeptides among staphylococci and enterococci was not detected, whereas 60% of Gram-negative bacilli were resistant to beta-lactams...
  20. ncbi request reprint Presence of mec genes and overproduction of beta-lactamase in the expression of low-level methicillin resistance among staphylococci
    E Petinaki
    Department of Microbiology, School of Medicine, University of Patras, Patras, Greece
    Chemotherapy 48:174-81. 2002
    ..aureus isolates, and 3 in CNS. Low-level methicillin resistance of staphylococci is correlated with the presence of the mecA gene and overproduction of beta-lactamase...
  21. ncbi request reprint Lincomycin resistance in methicillin-resistant Staphylococcus aureus strains of hospital origin
    I Spiliopoulou
    Department of Microbiology, School of Medicine, University of Patras, Greece
    J Chemother 1:377-83. 1989
    ..Membrane-protein profiles by polyacrylamide gel electrophoresis (PAGE) showed that LMRSA strains could belong to one group. This method proved useful and sensitive for characterization of LMRSA...
  22. doi request reprint Pitfalls in the identification of Enterococcus species and the detection of vanA and vanB genes
    M Papadimitriou-Olivgeris
    Division of Infectious Diseases, School of Medicine, University of Patras, Patras, Greece
    Lett Appl Microbiol 63:189-95. 2016
    ..GeneXpert(®) showed the same efficacy as ChromID VRE in detecting vanA-positive enterococci, but lower for vanB-gene detection...
  23. doi request reprint Co-colonization by multidrug-resistant bacteria in two Greek intensive care units
    M Papadimitriou-Olivgeris
    Division of Infectious Diseases, School of Medicine, University of Patras, 26504, Rion, Patras, Greece
    Eur J Clin Microbiol Infect Dis 34:1947-55. 2015
    ..1; CI 1.9-13.9) and MRSA colonization upon admission (aOR: 3.5; CI 1.2-10.1) and during ICU stay (aOR: 14.5; CI 2.1-100.1). Colonization by a multidrug pathogen could promote colonization by another...
  24. doi request reprint Virulence factors among Staphylococcus lugdunensis are associated with infection sites and clonal spread
    N Giormezis
    Department of Microbiology, School of Medicine, University of Patras, 26504, Rion, Patras, Greece
    Eur J Clin Microbiol Infect Dis 34:773-8. 2015
    ..Despite susceptibility to antimicrobials, the clonal expansion and carriage of virulence factors, combined with biofilm-producing ability, render this species an important pathogen that should not be ignored...
  25. doi request reprint Risk factors for enterococcal infection and colonization by vancomycin-resistant enterococci in critically ill patients
    M Papadimitriou-Olivgeris
    Division of Infectious Diseases, School of Medicine, University of Patras, Rion, 26504, Patras, Greece
    Infection 42:1013-22. 2014
    ..Our goal was to identify the prevalence and risk factors for VRE colonization upon ICU admission and during ICU stay, as well as, their impact in enterococcal infection including vancomycin-susceptible cases (VSE)...
  26. doi request reprint Clinical and microbiological profile of persistent coagulase-negative staphylococcal bacteraemia in neonates
    G Dimitriou
    Neonatal Intensive Care Unit, Department of Paediatrics, School of Medicine, University of Patras, Patras, Greece
    Clin Microbiol Infect 17:1684-90. 2011
    ..Isolates associated with persistent bacteraemia were more likely to produce biofilm, independently of the presence of the ica operon...
  27. ncbi request reprint Plasmid profiles of Acinetobacter and Enterobacter species of hospital origin: restriction endonuclease analysis of plasmid DNA and transformation of Escherichia coli by R plasmids
    I Spiliopoulou
    Department of Microbiology, School of Medicine, University of Patras, Greece
    J Chemother 4:72-7. 1992
    ..calcoaceticus and two E. cloacae endemic strains. Transformation experiments on Escherichia coli competent cells by three plasmids established the presence of R plasmids in the multi-resistant isolates...
  28. doi request reprint Toxoplasma gondii meningoencephalitis without cerebral MRI findings in a patient with ulcerative colitis under immunosuppressive treatment
    S F Assimakopoulos
    Division of Infectious Diseases, Department of Internal Medicine, University General Hospital of Patras, 26504, Patras, Greece
    Infection 43:589-93. 2015
    ..gondii infection, should include microscopic examination of CSF for parasite presence. ..
  29. doi request reprint A 12-year survey of methicillin-resistant Staphylococcus aureus infections in Greece: ST80-IV epidemic?
    E Drougka
    Department of Microbiology, School of Medicine, University of Patras, Patras, Greece National Reference Laboratory for Staphylococci, Patras, Greece
    Clin Microbiol Infect 20:O796-803. 2014
    ..The predominance of ST239-III in HA-MRSA infections was constant, whereas new clones have also emerged. Polyclonality was statistically significantly higher among CA-MRSA isolates and isolates from adult patients. ..
  30. ncbi request reprint A retrospective study of Pseudomonas aeruginosa isolation from clinical sources
    E D Anastassiou
    Department of Microbiology, School of Medicine, University of Patras, Greece
    J Chemother 1:240-3. 1989
    ..Our results show an overall P. aeruginosa isolation incidence of 10.6%, with its resistance to routinely used antibiotics being high but relatively low to the newer agents which have not been used extensively in our hospital...
  31. ncbi request reprint Evaluation of a novel method based on PCR Restriction Fragment Length Polymorphism Analysis of the tuf gene for the identification of Staphylococcus species
    F Kontos
    Department of Microbiology, School of Medicine, University of Thessalia, Papakyriazi 22, Larissa, Greece
    J Microbiol Methods 55:465-9. 2003
    ..A total of 258 clinical isolates were validated by this assay, and the results were in concordance with those obtained by the reference method of Kloos and Schleifer...
  32. doi request reprint Carbapenemase-producing Klebsiella pneumoniae bloodstream infection in critically ill patients: risk factors and predictors of mortality
    M Papadimitriou-Olivgeris
    Division of Infectious Diseases, Internal Medicine, School of Medicine, University of Patras, 26504, Rion, Patras, Greece
    Eur J Clin Microbiol Infect Dis . 2017
    ..The administration of tigecycline predisposes to the induction of bacteraemia. Appropriate antibiotic treatment is associated with better survival, while concomitant corticosteroid treatment is associated with mortality...
  33. doi request reprint Methicillin-resistant Staphylococcus aureus among companion and food-chain animals: impact of human contacts
    E Petinaki
    Department of Microbiology, School of Medicine, University of Thessalia, Larissa, Greece
    Clin Microbiol Infect 18:626-34. 2012
    ..On the basis of a review of the literature, epidemiological and evolutionary data for MRSA infections and carriage, risk factors and control strategies are presented...
  34. ncbi request reprint Sensitivity of the Cobas Amplicor system for detection of Mycobacterium tuberculosis in respiratory and extrapulmonary specimens
    E Fegou
    Department of Microbiology, School of Medicine, University of Patras, Greece
    Clin Microbiol Infect 11:593-6. 2005
    ..The sensitivity of CA-PCR ranged from 73.6% to 100% for AFB-positive samples, while sputa collected after bronchoscopy were the most useful specimens, with 70% sensitivity and 98.6% specificity among the AFB-negative samples...
  35. ncbi request reprint IgG and IgM concentration in the prolapsed human intervertebral disc and sciatica etiology
    I Spiliopoulou
    Department of Microbiology, University of Patras Medical School, Greece
    Spine (Phila Pa 1976) 19:1320-3. 1994
    ..These findings may be secondary to an inflammatory reaction close to the nerve root and prolapsed nucleus pulposus. Therefore, they may contribute in some way to the inflammatory origin of sciatica...
  36. doi request reprint Community-associated Staphylococcus aureus pneumonia among Greek children: epidemiology, molecular characteristics, treatment, and outcome
    A G Doudoulakakis
    Department of Microbiology, P and A Aglaia Kyriakou Children s Hospital, Athens, Greece
    Eur J Clin Microbiol Infect Dis 35:1177-85. 2016
    ..Treatment provided was effective in all but two patients, despite the relatively high minimum inhibitory concentration (MIC) of vancomycin and a high resistance to clindamycin. ..
  37. doi request reprint Performance of chromID® CARBA medium for carbapenemases-producing Enterobacteriaceae detection during rectal screening
    M Papadimitriou-Olivgeris
    Division of Infectious Diseases, School of Medicine, University of Patras, Patras, Greece
    Eur J Clin Microbiol Infect Dis 33:35-40. 2014
    ..5 % in clinical samples. Specificity was 91.2 % at the reading level and 100.0 % after Gram staining. chromID® CARBA performed with high accuracy among the phenotypic methods applied, giving early results...
  38. ncbi request reprint Adhesion of slime producing Staphylococcus epidermidis strains to PVC and diamond-like carbon/silver/fluorinated coatings
    M Katsikogianni
    Laboratory of Biomechanics and Biomedical Engineering, Department of Mechanical Engineering, University of Patras, Patras, Greece
    J Mater Sci Mater Med 17:679-89. 2006
    ..These results indicate that bacterial adhesion is influenced by the chemical properties of the polymeric surfaces, the surface roughness and the associated flow conditions...
  39. ncbi request reprint The possible role of locally produced cytokines in the pathogenesis of peritrochanteric fractures in the elderly
    I Spiliopoulou
    Department of Microbiology, School of Medicine, University of Patras, Greece
    Orthopedics 24:763-6. 2001
    ....
  40. ncbi request reprint Emergence of Staphylococcus hominis strains expressing low-level resistance to quinupristin/dalfopristin in Greece
    E Petinaki
    J Antimicrob Chemother 55:811-2. 2005
  41. ncbi request reprint Emergence of Enterococcus faecalis susceptible to quinupristin/dalfopristin in Greece
    E Petinaki
    Int J Antimicrob Agents 28:153-6. 2006
  42. ncbi request reprint Activity of linezolid against Gram-positive cocci: a multicentre study in Greek hospitals
    A Pratti
    Int J Antimicrob Agents 29:604-5. 2007
  43. ncbi request reprint Rapid increase in numbers of Staphylococcus epidermidis strains with reduced susceptibility to teicoplanin in Greece
    M Maniati
    Int J Antimicrob Agents 25:346-8. 2005