Torben Frøstrup Hansen
Hansen T, Christensen R, Andersen R, Sørensen F, Johnsson A, Jakobsen A. MicroRNA-126 and epidermal growth factor-like domain 7-an angiogenic couple of importance in metastatic colorectal cancer. Results from the Nordic ACT trial. Br J Cancer. 2013;109:1243-51 pubmed publisher
..As miRNA-126 may target VEGF-A as well as EGFL7, the results may provide predictive information in relation to next-generation anti-angiogenetics. ..
Hansen T, Nielsen B, Sørensen F, Johnsson A, Jakobsen A. Epidermal growth factor-like domain 7 predicts response to first-line chemotherapy and bevacizumab in patients with metastatic colorectal cancer. Mol Cancer Ther. 2014;13:2238-45 pubmed publisher
Hansen T, Nielsen B, Jakobsen A, Sørensen F. Intra-tumoural vessel area estimated by expression of epidermal growth factor-like domain 7 and microRNA-126 in primary tumours and metastases of patients with colorectal cancer: a descriptive study. J Transl Med. 2015;13:10 pubmed publisher
..Differential expression of miRNA-126 seems more pronounced in disseminated disease, which supports its role as a regulator in the metastatic process. ..
Hansen T, Andersen R, Olsen D, Sørensen F, Jakobsen A. Prognostic importance of circulating epidermal growth factor-like domain 7 in patients with metastatic colorectal cancer treated with chemotherapy and bevacizumab. Sci Rep. 2017;7:2388 pubmed publisher
..The findings call for further validation. ..