Torben Frøstrup Hansen

Summary

Publications

  1. doi Computer-assisted stereology and automated image analysis for quantification of tumor infiltrating lymphocytes in colon cancer
    Ann C Eriksen
    Danish Colorectal Cancer Center South, Vejle Hospital, Vejle, Denmark
    Diagn Pathol 12:65. 2017
  2. doi Prognostic importance of circulating epidermal growth factor-like domain 7 in patients with metastatic colorectal cancer treated with chemotherapy and bevacizumab
    Torben Frøstrup Hansen
    Danish Colorectal Cancer Center South, Vejle Hospital, Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark
    Sci Rep 7:2388. 2017
  3. pmc Intra-tumoural vessel area estimated by expression of epidermal growth factor-like domain 7 and microRNA-126 in primary tumours and metastases of patients with colorectal cancer: a descriptive study
    Torben Frøstrup Hansen
    Department of Oncology, Vejle Hospital, part of Lillebaelt Hospital, Kabbeltoft 25, 7100, Vejle, Denmark
    J Transl Med 13:10. 2015
  4. doi Epidermal growth factor-like domain 7 predicts response to first-line chemotherapy and bevacizumab in patients with metastatic colorectal cancer
    Torben Frøstrup Hansen
    Department of Oncology, Vejle Hospital, part of Lillebaelt Hospital, Vejle, Denmark Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark
    Mol Cancer Ther 13:2238-45. 2014
  5. pmc MicroRNA-126 and epidermal growth factor-like domain 7-an angiogenic couple of importance in metastatic colorectal cancer. Results from the Nordic ACT trial
    T F Hansen
    Department of Oncology, Vejle Hospital, Lillebaelt Hospital, Denmark
    Br J Cancer 109:1243-51. 2013
  6. doi Visualising and quantifying angiogenesis in metastatic colorectal cancer : A comparison of methods and their predictive value for chemotherapy response
    Torben Frøstrup Hansen
    Department of Oncology, Vejle Hospital, Vejle, Denmark
    Cell Oncol (Dordr) 36:341-50. 2013
  7. pmc The predictive value of microRNA-126 in relation to first line treatment with capecitabine and oxaliplatin in patients with metastatic colorectal cancer
    Torben Frøstrup Hansen
    Department of Oncology, Vejle Hospital, Kabbeltoft, Denmark
    BMC Cancer 12:83. 2012
  8. doi The predictive value of single nucleotide polymorphisms in the VEGF system to the efficacy of first-line treatment with bevacizumab plus chemotherapy in patients with metastatic colorectal cancer: results from the Nordic ACT trial
    Torben Frøstrup Hansen
    Danish Colorectal Cancer Group South, Vejle Hospital, University of Southern Denmark, Vejle, Denmark
    Int J Colorectal Dis 27:715-20. 2012
  9. doi MicroRNA-200b is downregulated in colon cancer budding cells
    Kirsten Nguyen Knudsen
    Danish Colorectal Cancer Center South, Vejle Hospital, part of Lillebaelt Hospital, Kabbeltoft 25, Vejle, Denmark
    PLoS ONE 12:e0178564. 2017
  10. pmc Intratumoral Heterogeneity of MicroRNA Expression in Rectal Cancer
    Anne Haahr Mellergaard Eriksen
    Danish Colorectal Cancer Center South, Vejle Hospital, Vejle, Denmark
    PLoS ONE 11:e0156919. 2016

Collaborators

  • Anders Jakobsen
  • Boye Schnack Nielsen
  • Jan Lindebjerg
  • Lars Henrik Jensen
  • Anne Haahr Mellergaard Eriksen
  • Flemming Brandt Sørensen
  • Kirsten Nguyen Knudsen
  • Rikke Fredslund Andersen
  • Ahmed Hussein Zedan
  • Ann C Eriksen
  • Søren Garm Blavnsfeldt
  • Palle Jörn Sloth Osther
  • Martin Kristensson
  • Rene dePont Christensen
  • Flemming B Sørensen
  • Niels Marcussen
  • Johnnie B Andersen
  • Mindaugas Pleckaitis
  • Sanne Kjær-Frifeldt
  • Ane Lindegaard Appelt
  • Niels Pallisgaard
  • René Holst

Detail Information

Publications17

  1. doi Computer-assisted stereology and automated image analysis for quantification of tumor infiltrating lymphocytes in colon cancer
    Ann C Eriksen
    Danish Colorectal Cancer Center South, Vejle Hospital, Vejle, Denmark
    Diagn Pathol 12:65. 2017
    ..The purpose of this study was to compare manual stereological estimates of TILs with automatic counts obtained by image analysis, and at the same time investigate the heterogeneity of TILs...
  2. doi Prognostic importance of circulating epidermal growth factor-like domain 7 in patients with metastatic colorectal cancer treated with chemotherapy and bevacizumab
    Torben Frøstrup Hansen
    Danish Colorectal Cancer Center South, Vejle Hospital, Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark
    Sci Rep 7:2388. 2017
    ..The findings call for further validation...
  3. pmc Intra-tumoural vessel area estimated by expression of epidermal growth factor-like domain 7 and microRNA-126 in primary tumours and metastases of patients with colorectal cancer: a descriptive study
    Torben Frøstrup Hansen
    Department of Oncology, Vejle Hospital, part of Lillebaelt Hospital, Kabbeltoft 25, 7100, Vejle, Denmark
    J Transl Med 13:10. 2015
    ....
  4. doi Epidermal growth factor-like domain 7 predicts response to first-line chemotherapy and bevacizumab in patients with metastatic colorectal cancer
    Torben Frøstrup Hansen
    Department of Oncology, Vejle Hospital, part of Lillebaelt Hospital, Vejle, Denmark Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark
    Mol Cancer Ther 13:2238-45. 2014
    ....
  5. pmc MicroRNA-126 and epidermal growth factor-like domain 7-an angiogenic couple of importance in metastatic colorectal cancer. Results from the Nordic ACT trial
    T F Hansen
    Department of Oncology, Vejle Hospital, Lillebaelt Hospital, Denmark
    Br J Cancer 109:1243-51. 2013
    ....
  6. doi Visualising and quantifying angiogenesis in metastatic colorectal cancer : A comparison of methods and their predictive value for chemotherapy response
    Torben Frøstrup Hansen
    Department of Oncology, Vejle Hospital, Vejle, Denmark
    Cell Oncol (Dordr) 36:341-50. 2013
    ..Here, we evaluated whether more general approaches to determine vessel density in primary tumours are equally predictive of chemotherapy response...
  7. pmc The predictive value of microRNA-126 in relation to first line treatment with capecitabine and oxaliplatin in patients with metastatic colorectal cancer
    Torben Frøstrup Hansen
    Department of Oncology, Vejle Hospital, Kabbeltoft, Denmark
    BMC Cancer 12:83. 2012
    ..The aim of the present study was to analyse the possible predictive value of miRNA-126 in relation to first line capecitabine and oxaliplatin (XELOX) in patients with metastatic colorectal cancer (mCRC)...
  8. doi The predictive value of single nucleotide polymorphisms in the VEGF system to the efficacy of first-line treatment with bevacizumab plus chemotherapy in patients with metastatic colorectal cancer: results from the Nordic ACT trial
    Torben Frøstrup Hansen
    Danish Colorectal Cancer Group South, Vejle Hospital, University of Southern Denmark, Vejle, Denmark
    Int J Colorectal Dis 27:715-20. 2012
    ..So far, no predictive markers have been identified. The aim was to investigate the possible predictive value of single nucleotide polymorphisms (SNPs) in the vascular endothelial growth factor (VEGF) system in this setting...
  9. doi MicroRNA-200b is downregulated in colon cancer budding cells
    Kirsten Nguyen Knudsen
    Danish Colorectal Cancer Center South, Vejle Hospital, part of Lillebaelt Hospital, Kabbeltoft 25, Vejle, Denmark
    PLoS ONE 12:e0178564. 2017
    ..The aim of this study was to investigate the expression of miR-200b in budding cells of colon cancer and the relationship with the EMT-markers E-cadherin, β-catenin and laminin-5γ2...
  10. pmc Intratumoral Heterogeneity of MicroRNA Expression in Rectal Cancer
    Anne Haahr Mellergaard Eriksen
    Danish Colorectal Cancer Center South, Vejle Hospital, Vejle, Denmark
    PLoS ONE 11:e0156919. 2016
    ..The aim of the present study was to assess the heterogeneity of a panel of selected miRNAs in rectal cancer, using two different technical approaches...
  11. doi Microvessel density and the association with single nucleotide polymorphisms of the vascular endothelial growth factor receptor 2 in patients with colorectal cancer
    Torben Frøstrup Hansen
    Department of Oncology, Danish Colorectal Cancer Group South, Vejle Hospital, Kabbeltoft 25, 7100, Vejle, Denmark
    Virchows Arch 456:251-60. 2010
    ..Moreover, an association between the SNPs and survival was demonstrated. The clinical implications of these findings need further investigations...
  12. doi Heterogeneity of miRNA expression in localized prostate cancer with clinicopathological correlations
    Ahmed Hussein Zedan
    Urological Research Center, Department of Urology, Vejle Hospital, Vejle, Denmark
    PLoS ONE 12:e0179113. 2017
    ..The aims of this study were to assess the impact of tumor heterogeneity, as demonstrated by a panel of selected miRNAs in PCa, and to correlate miRNA expression with risk profile and patient outcome...
  13. doi Association between the expression of microRNAs and the response of patients with locally advanced rectal cancer to preoperative chemoradiotherapy
    Anne Haahr Mellergaard Eriksen
    Department of Oncology, Danish Colorectal Cancer Center South, Vejle Hospital, 7100 Vejle, Denmark
    Oncol Lett 14:201-209. 2017
    ..The remaining miRNAs analyzed were not associated with TRG. The results of the present study highlight the clinical importance of miRNAs in LARC and underline the necessity for validation studies in this setting...
  14. doi Tumor-stroma ratio predicts recurrence in patients with colon cancer treated with neoadjuvant chemotherapy
    Torben Frøstrup Hansen
    a Danish Colorectal Cancer Center South, Vejle Hospital, Vejle, Denmark
    Acta Oncol . 2017
    ..The aim of this study was to analyze the ability of tumor-stroma ratio (TSR) to predict disease recurrence in patients with locally advanced colon cancer treated with neoadjuvant chemotherapy...
  15. pmc MicroRNA Expression Profiling to Identify and Validate Reference Genes for the Relative Quantification of microRNA in Rectal Cancer
    Anne Haahr Mellergaard Eriksen
    Danish Colorectal Cancer Center South, Center of Clinical Excellence, Vejle Hospital, Vejle, Denmark
    PLoS ONE 11:e0150593. 2016
    ..The aim of the present study was to identify stably expressed miRNAs applicable as normaliser candidates in future studies of miRNA expression in rectal cancer...
  16. pmc microRNA-17 Is the Most Up-Regulated Member of the miR-17-92 Cluster during Early Colon Cancer Evolution
    Kirsten Nguyen Knudsen
    Department of Clinical Pathology, Vejle Hospital, part of Lillebaelt Hospital, Vejle, Denmark Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark
    PLoS ONE 10:e0140503. 2015
    ..It is concluded that the expression of miR-17, miR-21, and miR-145 changes at early stages of the normal-adenoma-adenocarcinoma sequence. Thus, these microRNAs may play a role in the development of colon cancer. ..
  17. doi Clinical implications of genetic variations in the VEGF system in relation to colorectal cancer
    Torben Frøstrup Hansen
    Department of Oncology, Vejle Hospital, Kabbeltoft 25, 7100 Vejle, Denmark
    Pharmacogenomics 12:1681-93. 2011
    ..This review evaluates the literature on SNPs in relation to the risk of CRC and the possible prognostic and predictive value and argues for the role of these biomarkers in the future treatment of patients with CRC...