Ganesh Chandra Jagetia

Summary

Affiliation: Kasturba Medical College
Country: India

Publications

  1. ncbi Radioprotection by mangiferin in DBAxC57BL mice: a preliminary study
    G C Jagetia
    Department of Radiobiology, Kasturba Medical College Manipal, Karnataka 576104, India
    Phytomedicine 12:209-15. 2005
  2. ncbi Effect of Alstonia scholaris in enhancing the anticancer activity of berberine in the Ehrlich ascites carcinoma-bearing mice
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 104, Karnataka, India
    J Med Food 7:235-44. 2004
  3. ncbi Augmentation of wound healing by ascorbic acid treatment in mice exposed to gamma-radiation
    G C Jagetia
    Department ofRadiobiology, Kasturba Medical College, Manipal 576 104, India
    Int J Radiat Biol 80:347-54. 2004
  4. ncbi Evaluation of the radioprotective effect of bael leaf (Aegle marmelos) extract in mice
    G C Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 104, India
    Int J Radiat Biol 80:281-90. 2004
  5. ncbi Role of curcumin, a naturally occurring phenolic compound of turmeric in accelerating the repair of excision wound, in mice whole-body exposed to various doses of gamma-radiation
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    J Surg Res 120:127-38. 2004
  6. ncbi Effect of curcumin on radiation-impaired healing of excisional wounds in mice
    G C Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    J Wound Care 13:107-9. 2004
  7. ncbi Treatment with Alstonia scholaris enhances radiosensitivity in vitro and in vivo
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Cancer Biother Radiopharm 18:917-29. 2003
  8. ncbi Induction of developmental toxicity in mice treated with Alstonia scholaris (Sapthaparna) In utero
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Birth Defects Res B Dev Reprod Toxicol 68:472-8. 2003
  9. ncbi Modulation of antineoplastic activity of cyclophosphamide by Alstonia scholaris in the Ehrlich ascites carcinoma-bearing mice
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, Karnataka, India
    J Exp Ther Oncol 3:272-82. 2003
  10. ncbi The evaluation of nitric oxide scavenging activity of certain herbal formulations in vitro: a preliminary study
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Phytother Res 18:561-5. 2004

Collaborators

Detail Information

Publications63

  1. ncbi Radioprotection by mangiferin in DBAxC57BL mice: a preliminary study
    G C Jagetia
    Department of Radiobiology, Kasturba Medical College Manipal, Karnataka 576104, India
    Phytomedicine 12:209-15. 2005
    ..The administration of 400 mg/kg MGN induced 50% mortality, therefore LD50 of the drug was considered to be 400 mg/kg...
  2. ncbi Effect of Alstonia scholaris in enhancing the anticancer activity of berberine in the Ehrlich ascites carcinoma-bearing mice
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 104, Karnataka, India
    J Med Food 7:235-44. 2004
    ....
  3. ncbi Augmentation of wound healing by ascorbic acid treatment in mice exposed to gamma-radiation
    G C Jagetia
    Department ofRadiobiology, Kasturba Medical College, Manipal 576 104, India
    Int J Radiat Biol 80:347-54. 2004
    ....
  4. ncbi Evaluation of the radioprotective effect of bael leaf (Aegle marmelos) extract in mice
    G C Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 104, India
    Int J Radiat Biol 80:281-90. 2004
    ..To investigate the radioprotective activity of a leaf extract of bael leaf (Aegle marmelos) (AME) in mice exposed to different doses of gamma-radiation...
  5. ncbi Role of curcumin, a naturally occurring phenolic compound of turmeric in accelerating the repair of excision wound, in mice whole-body exposed to various doses of gamma-radiation
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    J Surg Res 120:127-38. 2004
    ..This study demonstrates that curcumin pretreatment has a conducive effect on the irradiated wound and could be a substantial therapeutic strategy in initiating and supporting the cascade of tissue repair processes in irradiated wounds...
  6. ncbi Effect of curcumin on radiation-impaired healing of excisional wounds in mice
    G C Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    J Wound Care 13:107-9. 2004
    ..To study the effect on wound contraction of pretreatment with various doses of curcumin (the most important active ingredient of the spice turmeric) in mice exposed to 6 Gy whole-body gamma radiation...
  7. ncbi Treatment with Alstonia scholaris enhances radiosensitivity in vitro and in vivo
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Cancer Biother Radiopharm 18:917-29. 2003
    ..Our study demonstrates that ASERS treatment enhances the effect of radiation and results in disease-free survival of the mice...
  8. ncbi Induction of developmental toxicity in mice treated with Alstonia scholaris (Sapthaparna) In utero
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Birth Defects Res B Dev Reprod Toxicol 68:472-8. 2003
    ..The teratogenic effect of hydroalcoholic extract of Alstonia scholaris (ASE) was studied in the pregnant Swiss albino mice administered with 0, 60, 120, 240, 360, and 480 mg/kg ASE on Day 11 of gestation...
  9. ncbi Modulation of antineoplastic activity of cyclophosphamide by Alstonia scholaris in the Ehrlich ascites carcinoma-bearing mice
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, Karnataka, India
    J Exp Ther Oncol 3:272-82. 2003
    ..The administration of 120 mg/kg of ASE 6 h before the administration of 25 mg/kg of CPA resulted in a drastic decline in the glutathione levels and increased the lipid peroxidation considerably when compared with either drug alone...
  10. ncbi The evaluation of nitric oxide scavenging activity of certain herbal formulations in vitro: a preliminary study
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Phytother Res 18:561-5. 2004
    ....
  11. ncbi Influence of naringin on ferric iron induced oxidative damage in vitro
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576104, India
    Clin Chim Acta 347:189-97. 2004
    ..It may become toxic when not handled carefully by cellular proteins and shielded from surrounding media. Naringin treatment may help to overcome the iron-induced toxic effects in vitro...
  12. ncbi The evaluation of nitric oxide scavenging activity of certain Indian medicinal plants in vitro: a preliminary study
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, Karnataka, India
    J Med Food 7:343-8. 2004
    ....
  13. ncbi Influence of seed extract of Syzygium Cumini (Jamun) on mice exposed to different doses of gamma-radiation
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal India
    J Radiat Res 46:59-65. 2005
    ..The SCE treatment protected mice against the gastrointestinal as well as bone marrow deaths and the DRF was found to be 1.24...
  14. ncbi Enhancement of radiation effect by Aphanamixis polystachya in mice transplanted with Ehrlich ascites carcinoma
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Biol Pharm Bull 28:69-77. 2005
    ....
  15. ncbi Aegle marmelos (L.) Correa inhibits the proliferation of transplanted Ehrlich ascites carcinoma in mice
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Biol Pharm Bull 28:58-64. 2005
    ..The acute toxicity study of AME showed that the drug was non-toxic up to a dose of 1750 mg/kg b. wt. The LD10 and LD50 was found to be 2000 and 2250 mg/kg...
  16. ncbi The effect of seasonal variation on the antineoplastic activity of Alstonia scholaris R. Br. in HeLa cells
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 104, India
    J Ethnopharmacol 96:37-42. 2005
    ..The extract of ASE was more powerful than the active principle echitamine present in ASE...
  17. ncbi Fruit extract of Aegle marmelos protects mice against radiation-induced lethality
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Integr Cancer Ther 3:323-32. 2004
    ....
  18. ncbi Evaluation of the radioprotective action of geriforte in mice exposed to different doses of gamma-radiation
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, India
    Am J Chin Med 32:551-67. 2004
    ..Geriforte was found to scavenge *OH, O2*- ABTS*+ and NO* in a dose-dependent manner. Our study demonstrates that geriforte is a good radioprotective agent and the optimum protective dose of 10 mg/kg was 1/475th of the LD50 dose...
  19. ncbi Polyherbal extract of septilin protects mice against whole body lethal dose of gamma radiation
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 104, India
    Phytother Res 18:619-23. 2004
    ..33%) which was used as a positive control. The LD(50) of Septilin was 1250 mg/kg as against the optimum protective dose of 100 mg/kg. Our study demonstrates Septilin as a good radioprotective agent...
  20. ncbi Ginger (Zingiber officinale Rosc.), a dietary supplement, protects mice against radiation-induced lethality: mechanism of action
    Ganesh Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Cancer Biother Radiopharm 19:422-35. 2004
    ..Ginger was found to scavenge *OH, O2*- and ABTS*+ radicals in a dose-dependent manner in vitro. The drug was nontoxic up to a dose of 1500 mg/kg body weight, the highest drug dose that could be tested for acute toxicity...
  21. ncbi Influence of ginger rhizome (Zingiber officinale Rosc) on survival, glutathione and lipid peroxidation in mice after whole-body exposure to gamma radiation
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 119, India
    Radiat Res 160:584-92. 2003
    ..ZOE also had a dose-dependent antimicrobial activity against Pseudomonas aeruginosa, Salmonella typhimurium, Escherichia coli and Candida albicans...
  22. ncbi Treatment of mice with a herbal preparation (mentat) protects against radiation-induced mortality
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Phytother Res 17:876-81. 2003
    ..wt., where no drug-induced mortality was observed. The LD50 dose of mentat was found to be 1.75 g/kg b. wt. Our study demonstrates that mentat can provide good radioprotection at a dose of 80 mg/kg, which is far below its toxic dose...
  23. ncbi Influence of the leaf extract of Mentha arvensis Linn. (mint) on the survival of mice exposed to different doses of gamma radiation
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Strahlenther Onkol 178:91-8. 2002
    ..The aim of the present study was to evaluate the radioprotective effect of Mentha arvensis (mint) on the survival of mice exposed to various doses of whole-body gamma radiation...
  24. ncbi Syzygium cumini (Jamun) reduces the radiation-induced DNA damage in the cultured human peripheral blood lymphocytes: a preliminary study
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, 576 119, Karnataka, Manipal, India
    Toxicol Lett 132:19-25. 2002
    ..Our study demonstrates that the leaf extract of S. cumini, a plant traditionally used to treat diabetic disorders protects against the radiation-induced DNA damage...
  25. ncbi The grapefruit flavanone naringin protects against the radiation-induced genomic instability in the mice bone marrow: a micronucleus study
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576119, India
    Mutat Res 519:37-48. 2002
    ....
  26. ncbi Cystone, an ayurvedic herbal drug imparts protection to the mice against the lethal effects of gamma-radiation: a preliminary study
    Ganesh Chandra Jagetia
    Dept of Radiobiology, Kasturba Medical College, Manipal 576 119, Karnataka, India
    Nahrung 46:332-6. 2002
    ..The optimum protection against irradiation was observed for 40 mg/kg cystone, where the highest number of survivors were reported by 30 days post irradiation and it was 8.34-fold greater than that of the irradiated control group...
  27. ncbi Correlation of micronuclei-induction with the cell survival in HeLa cells treated with a base analogue, azidothymidine (AZT) before exposure to different doses of gamma-radiation
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576119, India
    Toxicol Lett 139:33-43. 2003
    ..The biological response was studied by correlating the cell survival with MNBNC-induction. The cell survival and MNBNC-induction showed a close but inverse relationship and this relationship gave a best fit on the linear quadratic model...
  28. ncbi Evaluation of the effect of ascorbic acid treatment on wound healing in mice exposed to different doses of fractionated gamma radiation
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 119, India
    Radiat Res 159:371-80. 2003
    ....
  29. ncbi Effect of abana (a herbal preparation) on the radiation-induced mortality in mice
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576119, Karnataka, India
    J Ethnopharmacol 86:159-65. 2003
    ..The LD(50) dose of abana was found to be 1.8 g/kg body weight. Our study demonstrates the ability of abana as a good radioprotective agent and the optimum protective dose of abana was 1/90 of its LD(50) dose...
  30. ncbi Alteration in the glutathione, glutathione peroxidase, superoxide dismutase and lipid peroxidation by ascorbic acid in the skin of mice exposed to fractionated gamma radiation
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 119, India
    Clin Chim Acta 332:111-21. 2003
    ....
  31. ncbi Naringin, a citrus flavonone, protects against radiation-induced chromosome damage in mouse bone marrow
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576119, India
    Mutagenesis 18:337-43. 2003
    ..Our study demonstrates that naringin can protect mouse bone marrow cells against radiation-induced chromosomal damage...
  32. ncbi Evaluation of the radioprotective effect of Ageratum conyzoides Linn. extract in mice exposed to different doses of gamma radiation
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 119, India
    J Pharm Pharmacol 55:1151-8. 2003
    ..ACE was found to scavenge DPPH radicals in a concentration-dependent manner, indicating that the radioprotection afforded by ACE may be in part due to the scavenging of reactive oxygen species induced by ionizing radiation...
  33. ncbi Evaluation of the radioprotective effect of Aegle marmelos (L.) Correa in cultured human peripheral blood lymphocytes exposed to different doses of gamma-radiation: a micronucleus study
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576119, India
    Mutagenesis 18:387-93. 2003
    ....
  34. ncbi Evaluation of the radioprotective effect of the leaf extract of Syzygium cumini (Jamun) in mice exposed to a lethal dose of gamma-irradiation
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 119, Kamataka, India
    Nahrung 47:181-5. 2003
    ..wt. of SCE. However, the best protection was obtained for 30 mg/kg b.wt. SCE, where the number of, survivors after 30 days post-irradiation was highest (41.66%) when compared with the other doses of SCE...
  35. ncbi Effect of Sapthaparna (Alstonia scholaris Linn) in modulating the benzo(a)pyrene-induced forestomach carcinogenesis in mice
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576119, Karnataka, India
    Toxicol Lett 144:183-93. 2003
    ..The pre or post-treatment of mice with 4 mg/ml ASE also significantly reduced the frequency of BaP-induced MN in the splenocytes of treated animals...
  36. ncbi Radioprotection by oral administration of Aegle marmelos (L.) Correa in vivo
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, Karnataka, India
    J Environ Pathol Toxicol Oncol 24:315-32. 2005
    ..The drug was nontoxic up to a dose of 6000 mg/kg b.wt., the highest drug dose that could be tested for acute toxicity...
  37. ncbi Evaluation of the cytotoxic effect of the monoterpene indole alkaloid echitamine in-vitro and in tumour-bearing mice
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    J Pharm Pharmacol 57:1213-9. 2005
    ..Our study demonstrated that echitamine chloride possessed anti-tumour activity in-vitro and in-vivo...
  38. ncbi The evaluation of the acute toxicity and long term safety of hydroalcoholic extract of Sapthaparna (Alstonia scholaris) in mice and rats
    Manjeshwar Shrinath Baliga
    Department of Radiobiology, Kasturba Medical College, Manipal 576104, Karnataka, India
    Toxicol Lett 151:317-26. 2004
    ..The observed toxic effect of ASE may be due to the presence of echitamine. Our studies shows that at high doses, A. scholaris exhibited marked damage to all the major organs of the body...
  39. ncbi Effects of Aegle marmelos (L.) Correa on the peripheral blood and small intestine of mice exposed to gamma radiation
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    J Environ Pathol Toxicol Oncol 25:611-24. 2006
    ..The data clearly indicate that the AME significantly reduced the deleterious effect of radiation in the intestine and bone marrow of mouse and could be a useful agent in reducing the side effects of therapeutic radiation...
  40. ncbi Curcumin treatment enhances the repair and regeneration of wounds in mice exposed to hemibody gamma-irradiation
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Plast Reconstr Surg 115:515-28. 2005
    ....
  41. ncbi Modulation of doxorubicin-induced genotoxicity by Aegle marmelos in mouse bone marrow: a micronucleus study
    Ponemone Venkatesh
    Department of Radiobiology, Kasturba Medical College, Manipal, India Department of Human Nutrition, College of Applied Health Sciences, 1919 West Taylor Street, MC 517, University of Illinois at Chicago, Chicago, IL 60612 USA
    Integr Cancer Ther 6:42-53. 2007
    ..The greatest protection against DOX-induced genotoxicity was observed at 350 mg/kg AME. The protection against DOX-induced genotoxicity by AME may be due to inhibition of free radicals and increased antioxidant status...
  42. ncbi Triphala, an ayurvedic rasayana drug, protects mice against radiation-induced lethality by free-radical scavenging
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 104, Karnataka, India
    J Altern Complement Med 10:971-8. 2004
    ..Triphala was found to scavenge (.)OH, O(2) (.) 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonate) diammonium salt (ABTS)(.+) and NO(.) radicals in a dose dependent manner...
  43. ncbi Evaluation of anticancer activity of the alkaloid fraction of Alstonia scholaris (Sapthaparna) in vitro and in vivo
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 104, India
    Phytother Res 20:103-9. 2006
    ..5 and 18.3 days, respectively. The effective dose of 210 mg of ASERS was 3/10 of the LD50 dose, which increased the MST and AST up to 54 and 49.5 days, respectively...
  44. ncbi Treatment of mice with stem bark extract of Aphanamixis polystachya reduces radiation-induced chromosome damage
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Int J Radiat Biol 82:197-209. 2006
    ..The effect of ethyl acetate fraction of Aphanamixis polystachya (EAP) was investigated on the radiation-induced chromosome damage in the bone marrow cells of Swiss albino mice exposed to various doses of gamma-radiation...
  45. ncbi Evaluation of the antineoplastic activity of guduchi (Tinospora cordifolia) in Ehrlich ascites carcinoma bearing mice
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Biol Pharm Bull 29:460-6. 2006
    ..TCE exerted cytotoxic effect on tumor cells by reducing the GSH concentration and increase in LPx simultaneously...
  46. ncbi The evaluation of the radioprotective effect of chyavanaprasha (an ayurvedic rasayana drug) in mice exposed to lethal dose of gamma-radiation: a preliminary study
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Phytother Res 18:14-8. 2004
    ..The drug was non-toxic up to a dose of 6 g/kg b. wt., the highest drug dose that could be tested. Our study demonstrates that chyavanaprasha can provide good radioprotection at a very low non-toxic dose...
  47. ncbi Effect of mangiferin on radiation-induced micronucleus formation in cultured human peripheral blood lymphocytes
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 104, India
    Environ Mol Mutagen 46:12-21. 2005
    ..2,2-azino-bis-3-ethyl benzothiazoline-6-sulphonic acid) radicals in a dose-dependent manner. The results of this study indicate that MGN possesses radioprotective properties by suppressing the effects of free radicals...
  48. ncbi Modulation of radiation-induced alteration in the antioxidant status of mice by naringin
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 104, India
    Life Sci 77:780-94. 2005
    ..Our study demonstrates that naringin protects mouse liver and intestine against the radiation-induced damage by elevating the antioxidant status and reducing the lipid peroxidation...
  49. ncbi Ascorbic acid increases healing of excision wounds of mice whole body exposed to different doses of gamma-radiation
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576104, India
    Burns 33:484-94. 2007
    ....
  50. ncbi Antarth, a polyherbal preparation protects against the doxorubicin-induced toxicity without compromising its Antineoplastic activity
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Phytother Res 19:772-8. 2005
    ..The present study demonstrates that ANT protects mice against DOX-induced cardiotoxicity, without compromising the antineoplastic activity of DOX...
  51. ncbi Radioprotective effect of abana, a polyherbal drug following total body irradiation
    M S Baliga
    Department of Radiobiology, Kasturba Medical College, Manipal 576104, Karnataka, India
    Br J Radiol 77:1027-35. 2004
    ..Our results indicate that the radioprotective activity of abana may be due to free radical scavenging and increased GSH level in irradiated mice...
  52. ncbi Evaluation of nitric oxide scavenging activity of certain spices in vitro: a preliminary study
    Manjeshwar Shrinath Baliga
    Department of Radiobiology Kasturba Medical College, Manipal 576 119, Karnataka, India
    Nahrung 47:261-4. 2003
    ..The present results suggest that these spices might be potent and novel therapeutic agents for scavenging of NO and the regulation of pathological conditions caused by excessive generation of NO and its oxidation product, peroxynitrite...
  53. ncbi Vincristine increases the genomic instability in irradiated cultured human peripheral blood lymphocytes
    Ganesh Chandra Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 119, Karnataka, India
    Toxicol Lett 126:179-86. 2002
    ..This increase in multiple MNBNC was also dose dependent, however, the dose response was linear quadratic...
  54. ncbi The evaluation of the radioprotective effect of Triphala (an ayurvedic rejuvenating drug) in the mice exposed to gamma-radiation
    G C Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Phytomedicine 9:99-108. 2002
    ..The LD50 dose i.p. of triphala was found to be 280 mg/kg b. wt. Our study demonstrates the ability of triphala as a good radioprotective agent and the optimum protective dose of triphala was 1/28 of its LD50 dose...
  55. ncbi The attachment of V79 and human periodontal ligament fibroblasts on periodontally involved root surfaces following treatment with EDTA, citric acid, or tetracycline HCL: an SEM in vitro study
    R Viswa Chandra
    Department of Periodontics, College of Dental Surgery, Manipal, India
    J Contemp Dent Pract 7:44-59. 2006
    ....
  56. ncbi Antioxidant, anticlastogenic and radioprotective effect of Coleus aromaticus on Chinese hamster fibroblast cells (V79) exposed to gamma radiation
    B S Satish Rao
    Department of Radiobiology, Life Sciences Center, Manipal 576104, Karnataka, India
    Mutagenesis 21:237-42. 2006
    ..Overall, our results established an efficient antioxidant, anticlastogenic and radioprotective potential of CAE, which may be of great pharmacological importance...
  57. ncbi Inhibition of radiation-induced clastogenicity by Aegle marmelos (L.) correa in mice bone marrow exposed to different doses of gamma-radiation
    G C Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal 576 104, India
    Hum Exp Toxicol 26:111-24. 2007
    ..Our results demonstrate that one of the mechanism of reduction in the radiation-induced DNA damage in mice bone marrow by AME may be due to scavenging of free radicals and elevation in the antioxidant status, as previously reported...
  58. ncbi Trypan blue exclusion principle in the evaluation of fibroblast attachment in vitro using V79 cells on the conditioned root surface
    Rampalli Viswa Chandra
    Department of Periodontics, Manipal College of Dental Sciences, Manipal, Karnataka, India
    Quintessence Int 36:702-6. 2005
    ....
  59. ncbi Correlation between cell survival and micronuclei-induction in HeLa cells treated with adriamycin after exposure to various doses of gamma-radiation
    G C Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Toxicol Lett 115:183-93. 2000
    ..The relationship between cell survival and micronuclei induction was linear quadratic...
  60. ncbi Radiation-induced chromosomal aberrations in the bone marrow of mice exposed to various doses of gamma radiation
    G C Jagetia
    Department of Radiobiology, Kasturba Medical College, Karnataka, India
    Radiat Environ Biophys 32:109-17. 1993
    ..The best fit for the present data was by a linear-quadratic relationship between dose of radiation and the frequency of chromosomal aberrations...
  61. ncbi Correlation between cell survival and micronuclei formation in V79 cells treated with vindesine before exposure to different doses of gamma-radiation
    G C Jagetia
    Department of Radiobiology, Kasturba Medical College, 3rd Floor, Manipal, Karnataka 576 119, India
    Mutat Res 448:57-68. 2000
    ..The surviving fraction of V79 cells reduced with the increasing frequency of micronuclei in both groups and the relationship between micronuclei induction and cell survival could be fitted on a linear quadratic model...
  62. ncbi Alteration in the radiation-induced LD release in HeLa cells by acyclovir
    G C Jagetia
    Department of Radiobiology, Kasturba Medical College, Manipal, India
    Clin Chim Acta 294:129-38. 2000
    ..The LD measurements can serve as a short-term assay to evaluate the cytotoxicity of ACV or radiation in vitro...
  63. ncbi Evaluation of intraperitoneal vincristine in malignant peritoneal effusion
    K L Bairy
    Department of Pharmacology, Kasturba Medical College, Manipal 576 119
    Indian J Physiol Pharmacol 47:270-8. 2003
    ..Our experimental data suggests that intraperitoneal administration of vincristine is beneficial in malignant peritoneal effusion...