David Horn

Summary

Affiliation: Tel Aviv University
Location: Tel Aviv, Israel
URL: http://horn.tau.ac.il

Publications

  1. pmc Genomic DNA k-mer spectra: models and modalities
    Benny Chor
    School of Computer Science, Tel Aviv University, Klausner St, Ramat Aviv, Tel Aviv 39040, Israel
    Genome Biol 10:R108. 2009
  2. pmc Common peptides shed light on evolution of Olfactory Receptors
    Assaf Gottlieb
    School of Physics and Astronomy, Tel Aviv University, Tel Aviv, Israel
    BMC Evol Biol 9:91. 2009
  3. pmc Data mining of enzymes using specific peptides
    Uri Weingart
    School of Physics and Astronomy, Tel Aviv University, Tel Aviv 69978, Israel
    BMC Bioinformatics 10:446. 2009
  4. pmc UFFizi: a generic platform for ranking informative features
    Assaf Gottlieb
    Tel Aviv University, Ramat Aviv, Israel
    BMC Bioinformatics 11:300. 2010
  5. ncbi request reprint Novel clustering algorithm for microarray expression data in a truncated SVD space
    David Horn
    School of Physics and Astronomy, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel
    Bioinformatics 19:1110-5. 2003
  6. ncbi request reprint Dynamic proximity of spatio-temporal sequences
    David Horn
    School of Physics and Astronomy, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel
    IEEE Trans Neural Netw 15:1002-8. 2004
  7. ncbi request reprint Modeling of synchronized bursting events: the importance on inhomogeneity
    Erez Persi
    School of Physics and Astronomy, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel
    Neural Comput 16:2577-95. 2004
  8. pmc Functional representation of enzymes by specific peptides
    Vered Kunik
    School of Computer Science, Tel Aviv University, Tel Aviv, Israel
    PLoS Comput Biol 3:e167. 2007
  9. pmc Unsupervised learning of natural languages
    Zach Solan
    School of Physics and Astronomy, Tel Aviv University, Tel Aviv 69978, Israel
    Proc Natl Acad Sci U S A 102:11629-34. 2005
  10. ncbi request reprint Nucleotide variation of regulatory motifs may lead to distinct expression patterns
    Liat Segal
    Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    Bioinformatics 23:i440-9. 2007

Collaborators

Detail Information

Publications16

  1. pmc Genomic DNA k-mer spectra: models and modalities
    Benny Chor
    School of Computer Science, Tel Aviv University, Klausner St, Ramat Aviv, Tel Aviv 39040, Israel
    Genome Biol 10:R108. 2009
    ....
  2. pmc Common peptides shed light on evolution of Olfactory Receptors
    Assaf Gottlieb
    School of Physics and Astronomy, Tel Aviv University, Tel Aviv, Israel
    BMC Evol Biol 9:91. 2009
    ..Their evolution and their expansion in the vertebrate genomes was the subject of many studies. In this paper we apply a motif-based approach to this problem in order to uncover evolutionary characteristics...
  3. pmc Data mining of enzymes using specific peptides
    Uri Weingart
    School of Physics and Astronomy, Tel Aviv University, Tel Aviv 69978, Israel
    BMC Bioinformatics 10:446. 2009
    ..We devise the Data Mining of Enzymes (DME) methodology that allows for searching SPs on arbitrary proteins, determining from its sequence whether a protein is an enzyme and what the enzyme's EC classification is...
  4. pmc UFFizi: a generic platform for ranking informative features
    Assaf Gottlieb
    Tel Aviv University, Ramat Aviv, Israel
    BMC Bioinformatics 11:300. 2010
    ..Unsupervised Feature Filtering (UFF) is such a method, based on an entropy measure of Singular Value Decomposition (SVD), ranking features and selecting a group of preferred ones...
  5. ncbi request reprint Novel clustering algorithm for microarray expression data in a truncated SVD space
    David Horn
    School of Physics and Astronomy, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel
    Bioinformatics 19:1110-5. 2003
    ..The clustering algorithm used here is the quantum clustering method that has one free scale parameter. Although the method is not hierarchical, it can be modified to allow hierarchy in terms of this scale parameter...
  6. ncbi request reprint Dynamic proximity of spatio-temporal sequences
    David Horn
    School of Physics and Astronomy, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel
    IEEE Trans Neural Netw 15:1002-8. 2004
    ..Other types of spatio-temporal sequences need the introduction of hidden neurons, and/or the use of a kernel variant of the SVM approach. The latter is being defined as a recurrent support vector network (RSVN)...
  7. ncbi request reprint Modeling of synchronized bursting events: the importance on inhomogeneity
    Erez Persi
    School of Physics and Astronomy, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel
    Neural Comput 16:2577-95. 2004
    ..Thus, we can account for the interesting appearance of Levy distributions in the data...
  8. pmc Functional representation of enzymes by specific peptides
    Vered Kunik
    School of Computer Science, Tel Aviv University, Tel Aviv, Israel
    PLoS Comput Biol 3:e167. 2007
    ..Overall, SPs both form a very useful tool for enzyme functional classification and bear responsibility for the catalytic biological function carried out by enzymes...
  9. pmc Unsupervised learning of natural languages
    Zach Solan
    School of Physics and Astronomy, Tel Aviv University, Tel Aviv 69978, Israel
    Proc Natl Acad Sci U S A 102:11629-34. 2005
    ..This unsupervised algorithm is capable of learning complex syntax, generating grammatical novel sentences, and proving useful in other fields that call for structure discovery from raw data, such as bioinformatics...
  10. ncbi request reprint Nucleotide variation of regulatory motifs may lead to distinct expression patterns
    Liat Segal
    Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    Bioinformatics 23:i440-9. 2007
    ..The extracted motifs are assessed for their likely cis-regulatory function by calculating the expression coherence (EC) of the corresponding genes, across a set of biological conditions...
  11. doi request reprint Biological roles of specific peptides in enzymes
    Yasmine Meroz
    School of Physics and Astronomy, Tel Aviv University, Tel Aviv 69978, Israel
    Proteins 72:606-12. 2008
    ..Finally we show that SPs can partially resolve outstanding difficult problems of convergent evolution by representing correctly enzyme functions in spite of remote homologies in sequence and in structure...
  12. pmc Inversion symmetry of DNA k-mer counts: validity and deviations
    Sagi Shporer
    Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv, 69978, Israel
    BMC Genomics 17:696. 2016
    ..The existence of IS has been demonstrated in the literature, and other pair-wise candidate symmetries (e.g. reverse or complement) have been ruled out...
  13. pmc Systematic analysis of compositional order of proteins reveals new characteristics of biological functions and a universal correlate of macroevolution
    Erez Persi
    School of Physics and Astronomy, Tel Aviv University, Tel Aviv, Israel
    PLoS Comput Biol 9:e1003346. 2013
    ..The results indicate a mechanism of genomic 'innovation' at the peptide level, involved in protein elongation, shaped in a universal manner by mutational and selective forces. ..
  14. pmc Peptide markers of aminoacyl tRNA synthetases facilitate taxa counting in metagenomic data
    Erez Persi
    School of Physics and Astronomy, Tel Aviv University, Tel Aviv 69978, Israel
    BMC Genomics 13:65. 2012
    ..It would be advantageous to have a method that is applicable directly to short sequences, of the kind extracted from samples in modern metagenomic research. This is achieved by the technique proposed here...
  15. pmc Deriving enzymatic and taxonomic signatures of metagenomes from short read data
    Uri Weingart
    School of Physics and Astronomy, Tel Aviv University, Tel Aviv 69978, Israel
    BMC Bioinformatics 11:390. 2010
    ..Relative amounts of different EC categories define the enzymatic spectrum, without the need to perform genomic assemblies of short reads...
  16. ncbi request reprint Syntactic structures in languages and biology
    David Horn
    School of Physics and Astronomy, Tel Aviv University, 69978, Tel Aviv, Israel
    Cogn Process 9:153-8. 2008
    ..The underlying principles of these syntactic algorithms and some of their results will be described...