Patrizia Chiusolo

Summary

Affiliation: Catholic University
Country: Italy

Publications

  1. doi request reprint Salivary proteomic analysis and acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
    Patrizia Chiusolo
    Hematology Department, Universita Cattolica S Cuore, Rome, Italy
    Biol Blood Marrow Transplant 19:888-92. 2013
  2. doi request reprint The role of MTHFR and RFC1 polymorphisms on toxicity and outcome of adult patients with hematological malignancies treated with high-dose methotrexate followed by leucovorin rescue
    Patrizia Chiusolo
    Department of Hematology, Universita Cattolica del Sacro Cuore, Largo A Gemelli 8, 00168, Rome, Italy
    Cancer Chemother Pharmacol 69:691-6. 2012
  3. ncbi request reprint Analysis of MTHFR polymorphisms and P16 methylation and their correlation with clinical-biological features of multiple myeloma
    Patrizia Chiusolo
    Hematology Department, Universita Cattolica del Sacro Cuore, L go Gemelli 8, 00168, Rome, Italy
    Ann Hematol 85:474-7. 2006
  4. ncbi request reprint Methylenetetrahydrofolate reductase genotypes do not play a role in acute lymphoblastic leukemia pathogenesis in the Italian population
    Patrizia Chiusolo
    Istituto di Ematologia, Policlinico Gemelli, Largo A Gemelli 8, 00168 Rome, Italy
    Haematologica 89:139-44. 2004
  5. doi request reprint Efficacy of lenalidomide plus dexamethasone for POEMS syndrome relapsed after autologous peripheral stem-cell transplantation
    Barbara Vannata
    Department of Hematology, Catholic University of the Sacred Heart, Hospital A Gemelli, Largo A Gemelli 8, Rome, Italy
    Am J Hematol 87:641-2. 2012
  6. ncbi request reprint Immune recovery of lymphocyte subsets 6 years after autologous peripheral blood stem cell transplantation (PBSCT) for lymphoproliferative diseases. A comparison between NHL, HD and MM in group of 149 patients
    Luca Laurenti
    Divisione di Ematologia, Universita Cattolica del Sacro Cuore, Rome, Italy
    Leuk Lymphoma 45:2063-70. 2004
  7. ncbi request reprint MTHFR polymorphisms' influence on outcome and toxicity in acute lymphoblastic leukemia patients
    Patrizia Chiusolo
    Hematology Department, Universita Cattolica del Sacro Cuore, Largo A Gemelli 8, 00168 Rome, Italy
    Leuk Res 31:1669-74. 2007
  8. doi request reprint Low-dose valganciclovir as preemptive therapy for cytomegalovirus infection occurring in allogeneic stem cell transplant recipients
    Mariangela Palladino
    Department of Hematology, Universita Cattolica del Sacro Cuore, Rome, Italy
    Acta Haematol 123:230-4. 2010
  9. doi request reprint Comparison between oral and intravenous fludarabine plus cyclophosphamide regime as front-line therapy in patients affected by chronic lymphocytic leukaemia: influence of biological parameters on the clinical outcome
    Luca Laurenti
    Istituto di Ematologia, Policlinico A Gemelli, Universita Cattolica del Sacro Cuore, Rome, Italy
    Ann Hematol 90:59-65. 2011
  10. doi request reprint Peripherally inserted central catheters (PICCs) in the management of oncohematological patients submitted to autologous stem cell transplantation
    Silvia Bellesi
    Hematology Department, Universita Cattolica S Cuore, Largo A Gemelli 8, 00168, Rome, Italy
    Support Care Cancer 21:531-5. 2013

Collaborators

Detail Information

Publications40

  1. doi request reprint Salivary proteomic analysis and acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
    Patrizia Chiusolo
    Hematology Department, Universita Cattolica S Cuore, Rome, Italy
    Biol Blood Marrow Transplant 19:888-92. 2013
    ..01) Further studies are needed to clarify the role of these proteins as a marker of GVHD or as an index of mucosal inflammation...
  2. doi request reprint The role of MTHFR and RFC1 polymorphisms on toxicity and outcome of adult patients with hematological malignancies treated with high-dose methotrexate followed by leucovorin rescue
    Patrizia Chiusolo
    Department of Hematology, Universita Cattolica del Sacro Cuore, Largo A Gemelli 8, 00168, Rome, Italy
    Cancer Chemother Pharmacol 69:691-6. 2012
    ....
  3. ncbi request reprint Analysis of MTHFR polymorphisms and P16 methylation and their correlation with clinical-biological features of multiple myeloma
    Patrizia Chiusolo
    Hematology Department, Universita Cattolica del Sacro Cuore, L go Gemelli 8, 00168, Rome, Italy
    Ann Hematol 85:474-7. 2006
    ..However, controversial data have been published regarding a protective role of variant alleles of MTHFR on MM...
  4. ncbi request reprint Methylenetetrahydrofolate reductase genotypes do not play a role in acute lymphoblastic leukemia pathogenesis in the Italian population
    Patrizia Chiusolo
    Istituto di Ematologia, Policlinico Gemelli, Largo A Gemelli 8, 00168 Rome, Italy
    Haematologica 89:139-44. 2004
    ..Previous studies have suggested that individuals with the MTHFR 677TT, 1298AC and 1298CC have a lower risk of adult acute lymphoblastic leukemia (ALL)...
  5. doi request reprint Efficacy of lenalidomide plus dexamethasone for POEMS syndrome relapsed after autologous peripheral stem-cell transplantation
    Barbara Vannata
    Department of Hematology, Catholic University of the Sacred Heart, Hospital A Gemelli, Largo A Gemelli 8, Rome, Italy
    Am J Hematol 87:641-2. 2012
    ..Here, we report the successful use of lenalidomide in a patient who relapsed after aPBSCT...
  6. ncbi request reprint Immune recovery of lymphocyte subsets 6 years after autologous peripheral blood stem cell transplantation (PBSCT) for lymphoproliferative diseases. A comparison between NHL, HD and MM in group of 149 patients
    Luca Laurenti
    Divisione di Ematologia, Universita Cattolica del Sacro Cuore, Rome, Italy
    Leuk Lymphoma 45:2063-70. 2004
    ..Immunological recovery was similar in all 3 groups. Moreover, the recovery of all subsets evaluated was similarly demonstrated within 6 years after aPBSCT...
  7. ncbi request reprint MTHFR polymorphisms' influence on outcome and toxicity in acute lymphoblastic leukemia patients
    Patrizia Chiusolo
    Hematology Department, Universita Cattolica del Sacro Cuore, Largo A Gemelli 8, 00168 Rome, Italy
    Leuk Res 31:1669-74. 2007
    ..02). In the same subgroup we confirmed the role of 677TT variant on toxicity during MTX treatment (p=0.003)...
  8. doi request reprint Low-dose valganciclovir as preemptive therapy for cytomegalovirus infection occurring in allogeneic stem cell transplant recipients
    Mariangela Palladino
    Department of Hematology, Universita Cattolica del Sacro Cuore, Rome, Italy
    Acta Haematol 123:230-4. 2010
    ..We conclude that oral administration of valganciclovir can induce clearance of CMV viral load in about 2 weeks; moreover, lower-dose oral valganciclovir (900 mg/day) has a comparable efficacy to the proposed standard dose (1,800 mg/day)...
  9. doi request reprint Comparison between oral and intravenous fludarabine plus cyclophosphamide regime as front-line therapy in patients affected by chronic lymphocytic leukaemia: influence of biological parameters on the clinical outcome
    Luca Laurenti
    Istituto di Ematologia, Policlinico A Gemelli, Universita Cattolica del Sacro Cuore, Rome, Italy
    Ann Hematol 90:59-65. 2011
    ..We confirm that FC is an effective regimen with mild toxicities; it could be recommended for patients with low-risk biological parameters who represent, in our experience, about 30% of the total...
  10. doi request reprint Peripherally inserted central catheters (PICCs) in the management of oncohematological patients submitted to autologous stem cell transplantation
    Silvia Bellesi
    Hematology Department, Universita Cattolica S Cuore, Largo A Gemelli 8, 00168, Rome, Italy
    Support Care Cancer 21:531-5. 2013
    ....
  11. doi request reprint MTHFR polymorphisms involved in vitamin B12 deficiency associated with atrophic gastritis
    Mariangela Palladino
    Hematology Department, Catholic University, L go A Gemelli 8, 00168 Rome, Italy
    Biochem Genet 47:645-50. 2009
    ....
  12. doi request reprint Low incidence of secondary neoplasia after autotransplantation for lymphoproliferative disease: the role of pre-transplant therapy
    Luca Laurenti
    Department of Haematology, Universita Cattolica del Sacro Cuore Roma, Rome, Italy
    Clin Transplant 22:191-9. 2008
    ..The low incidence of secondary solid tumors could be caused by the absence of total body irradiation as part of the conditioning regimen or the short follow-up...
  13. ncbi request reprint Mitoxantrone, carboplatin, cytosine arabinoside, and methylprednisolone followed by autologous peripheral blood stem cell transplantation: a salvage regimen for patients with refractory or recurrent non-Hodgkin lymphoma
    Federica Sora
    Istituto di Ematologia, Universita Cattolica del Sacro Cuore di Roma, Italy
    Cancer 106:859-66. 2006
    ....
  14. doi request reprint Oral fludarabine and cyclophosphamide as front-line chemotherapy in patients with chronic lymphocytic leukemia. The impact of biological parameters in the response duration
    Luca Laurenti
    Istituto di Ematologia, Policlinico A Gemelli, Universita Cattolica del Sacro Cuore, Rome, Italy
    Ann Hematol 87:891-8. 2008
    ..The oral combination of fludarabine and cyclophosphamide is an effective, safe, and well-tolerated regimen that, if confirmed with larger series, will be appropriate especially in patients with low risk biological parameters...
  15. pmc Influence of the JAK2 V617F mutation and inherited thrombophilia on the thrombotic risk among patients with essential thrombocythemia
    Valerio De Stefano
    Institute of Hematology, Catholic University, Largo Gemelli 8, 00168 Rome, Italy
    Haematologica 94:733-7. 2009
    ..In conclusion, in the younger patients with ET the thrombotic risk is higher in the JAK2 V617F-mutated and is further increased by the presence of inherited thrombophilia...
  16. doi request reprint Early diagnosis followed by front-line autologous peripheral blood stem cell transplantation for patients affected by POEMS syndrome
    Luca Laurenti
    Haematology Institute, Universita Cattolica del Sacro Cuore, Rome, Italy
    Leuk Res 32:1309-12. 2008
    ..In conclusion early diagnosis is crucial to obtain best response and improve clinical outcome...
  17. ncbi request reprint Highly active antiretroviral therapy and allogeneic CD34(+) peripheral blood progenitor cells transplantation in an HIV/HCV coinfected patient with acute myeloid leukemia
    Federica Sora
    Istituto di Ematologia, Universita Cattolica Sacro Cuore, Rome, Italy
    Exp Hematol 30:279-84. 2002
    ..To evaluate the safety, feasibility, and efficacy of allogeneic stem cell transplantation (SCT) for acute myelogenous leukemia (AML) in a young female coinfected by HIV and HCV undergoing highly active antiretroviral therapy (HAART)...
  18. ncbi request reprint Glutamine-enriched parenteral nutrition after autologous peripheral blood stem cell transplantation: effects on immune reconstitution and mucositis
    Nicola Piccirillo
    Hematology Institute, Università Cattolica del Sarco Cuore, Rome, Italy
    Haematologica 88:192-200. 2003
    ....
  19. doi request reprint Prospective evaluation of epstein-barr virus reactivation after stem cell transplantation: association with monoclonal gammopathy
    Patrizia Chiusolo
    Institute of Haematology, Rome, Italy
    J Clin Immunol 30:894-902. 2010
    ..All patients with PTLD developed ╬│-peak and in five of them MG was identified. MG is consistently associated with EBV DNA-emia and may help identification of progression to PTLD after allogeneic SCT...
  20. ncbi request reprint Hormonal replacement therapy after stem cell transplantation
    Paola Piccioni
    Instituto di Ematologia, Universita Cattolica del Sacro Cuore, Largo Agostino Gemelli 8, 00168 Rome, Italy
    Maturitas 49:327-33. 2004
    ..To evaluate HRT compliance and efficacy in the treatment of symptomatic ovarian failure in pre-menopausal women after stem cell transplantation (SCT) for malignancies...
  21. ncbi request reprint Hyperleukocytosis and leukostasis: management of a medical emergency
    Sabrina Giammarco
    a Department of Hematology, Universita Cattolica del Sacro Cuore, Rome, Italy
    Expert Rev Hematol . 2016
    ..Although hyperleukocytosis and tumour lysis syndrome are still a challenge for clinicians, a better prognosis for these conditions is emerging in the last years...
  22. ncbi request reprint Kinetics of hemopoietic recovery after peripheral blood stem cell transplantation: impact of stem cell purification and G-CSF
    Nicola Piccirillo
    Istituto di Semeiotica Medica, Divisione di Ematologia, Universita Cattolica del Sacro Cuore, Rome, Italy
    Am J Hematol 69:7-14. 2002
    ..In conclusion, these preliminary data suggest that G-CSF is useful if given early after CD34(+) PBSCT. CD34(+) PBSCT may overall require a significant increase of resource utilization that should be outweighed by proven clinical benefit...
  23. ncbi request reprint Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells
    Aleksandar Petlickovski
    International Centre for Genetic Engineering and Biotechnology Outstation Monterotondo, Rome, Italy
    Blood 105:4820-7. 2005
    ..These data demonstrate that only sustained BCR signaling can promote survival of CLL B cells and indicate that the main difference between CLL with mutated and unmutated V(H) genes may reside in the availability of such stimulation...
  24. doi request reprint Incidence and clinical impact of extended-spectrum-beta-lactamase (ESBL) production and fluoroquinolone resistance in bloodstream infections caused by Escherichia coli in patients with hematological malignancies
    Enrico M Trecarichi
    Institute of Infectious Diseases, Catholic University of the Sacred Heart, Rome, Italy
    J Infect 58:299-307. 2009
    ..Particular attention was focused on defining the impact of extended-spectrum-beta-lactamase (ESBL) production and fluoroquinolone resistance by the bacterial isolates on mortality...
  25. doi request reprint Promoter methylation of DAPK1, E-cadherin and thrombospondin-1 in de novo and therapy-related myeloid neoplasms
    Mariangela Greco
    Istituto di Ematologia, Universita Cattolica del Sacro Cuore, Roma, Italy
    Blood Cells Mol Dis 45:181-5. 2010
    ....
  26. doi request reprint Severe veno-occlusive disease after autologous peripheral blood stem cell transplantation for high-grade non-Hodgkin lymphoma: report of a successfully managed case and a literature review of veno-occlusive disease
    Mariangela Palladino
    Department of Hematology, Catholic University of Sacred Heart, Faculty of Medicine, Rome, Italy
    Clin Transplant 22:837-41. 2008
    ..The literature on VOD has been reviewed...
  27. ncbi request reprint Work-related acute leukemia and mucor mycosis in a boat-builder
    Nicola Magnavita
    Institute of Occupational Medicine, Catholic University School of Medicine, Rome, Italy
    Haematologica 87:ECR42. 2002
  28. doi request reprint Role of 18F-FDG PET-CT for evaluating the response to reduced-intensity conditioning allogeneic transplant in heavily pre-treated patients with chronic lymphocytic leukemia: preliminary results in nine patients
    Silvia Taralli
    Institute of Nuclear Medicine, Policlinico Universitario A Gemelli, Universita Cattolica del Sacro Cuore, L go A Gemelli 8, 00168, Rome, Italy
    Ann Nucl Med 26:764-8. 2012
    ....
  29. pmc Allogeneic transplantation for chronic lymphocytic leukemia
    Luca Laurenti
    Istituto di Ematologia, Policlinico A Gemelli, Universita Cattolica del Sacro Cuore, Rome, Italy
    Mediterr J Hematol Infect Dis 2:e2010026. 2010
    ..Disease relapse remains the major cause of failure after RIC allo-HCT in CLL patients.Sensitive minimal residual disease (MRD) quantification has strong prognostic impact after transplant...
  30. ncbi request reprint Low-dose thalidomide in combination with oral fludarabine and cyclophosphamide is ineffective in heavily pre-treated patients with chronic lymphocytic leukemia
    Luca Laurenti
    Department of Haematology, Catholic University of Sacred Heart of Rome, Italy
    Leuk Res 31:253-6. 2007
    ..Serum TNF-alpha levels did not show any decrease during treatment. Low-dose thalidomide is not effective in CLL patients with refractory disease...
  31. ncbi request reprint Cytomegalovirus reactivation during alemtuzumab therapy for chronic lymphocytic leukemia: incidence and treatment with oral ganciclovir
    Luca Laurenti
    Divisione di Ematologia, Istituto di Ematologia, Universita Cattolica Sacro Cuore, Largo A Gemelli, 8 00168 Roma
    Haematologica 89:1248-52. 2004
    ..No prospective reports currently provide results of the use of oral ganciclovir as pre-emptive therapy in patients with CMV reactivation during alemtuzumab treatment...
  32. ncbi request reprint Periodic morphologic, cytogenetic and clonality evaluation after autologous peripheral blood progenitor cell transplantation in patients with lymphoproliferative malignancies
    Luca Laurenti
    Istituto di Semeiotica Medica, Divisione di Ematologia, Policlinico A Gemelli, Largo A Gemelli, 8 00168 Rome, Italy
    Haematologica 87:59-66. 2002
    ....
  33. ncbi request reprint Negative prognostic value of glutathione S-transferase (GSTM1 and GSTT1) deletions in adult acute myeloid leukemia
    Maria Teresa Voso
    Istituto di Ematologia, Universita Cattolica S Cuore and Dipartmento di Biotecnologie Cellulari ed Ematologia, Universita La Sapienza, Rome, Italy
    Blood 100:2703-7. 2002
    ..003). In conclusion, individuals with GSTM1 or GSTT1 deletions (or deletions of both) may have an enhanced resistance to chemotherapy and a shorter survival...
  34. ncbi request reprint Dasatinib restores full donor chimerism in a patient with imatinib-resistant Ph+ ALL relapsing after unrelated cord blood transplantation
    Giovanni Reddiconto
    Leuk Lymphoma 48:2054-7. 2007
  35. ncbi request reprint Secondary Ph+ acute lymphoblastic leukemia after temozolomide
    Serena De Vita
    Ann Hematol 84:760-2. 2005
  36. ncbi request reprint High prevalence of the JAK2 V617F mutation in patients with extrahepatic portal vein thrombosis
    Valerio De Stefano
    Hepatology 45:831-2; author reply 832-3. 2007
  37. ncbi request reprint Report of a novel kindred with antithrombin heparin-binding site variant (47 Arg to His): demand for an automated progressive antithrombin assay to detect molecular variants with low thrombotic risk
    Elena Rossi
    Thromb Haemost 98:695-7. 2007
  38. doi request reprint The JAK2 V617F mutation in patients with cerebral venous thrombosis: a rebuttal
    Valerio De Stefano
    Thromb Haemost 99:1121. 2008
  39. doi request reprint Simultaneous double mismatched cord blood transplantation in a young patient with secondary myelodysplastic syndrome: feasibility and complications
    Michela Tarnani
    Leuk Lymphoma 49:821-3. 2008
  40. ncbi request reprint Rituximab for pure red cell aplasia after ABO-mismatched allogeneic peripheral blood progenitor cell transplantation
    Federica Sora
    Transfusion 45:643-5. 2005