Carlo Nucci

Summary

Affiliation: University of Rome Tor Vergata
Location: Rome, Italy

Publications

  1. ncbi request reprint Apoptosis in the dorsal lateral geniculate nucleus after monocular deprivation involves glutamate signaling, NO production, and PARP activation
    C Nucci
    Department of Biopathology, Chair of Physiopathological Optics, University of Rome Tor Vergata, Via O Raimondo, Rome, 00173, Italy
    Biochem Biophys Res Commun 278:360-7. 2000
  2. ncbi request reprint Neurochemical evidence to implicate elevated glutamate in the mechanisms of high intraocular pressure (IOP)-induced retinal ganglion cell death in rat
    Carlo Nucci
    Physiopathological Optics, Department of Biopathology, University of Rome Tor Vergata, Rome, Italy
    Neurotoxicology 26:935-41. 2005
  3. doi request reprint Age-specific changes in the prevalence and management of optically correctable visual impairment between 1988 and 2000: the Ponza Eye Study
    C Cedrone
    Physiopathological Optics, Department of Biopathology and Diagnostic Imaging, University of Rome Tor Vergata, Rome, Italy
    Eye (Lond) 23:522-9. 2009
  4. ncbi request reprint Prevalence of blindness and low vision in an Italian population: a comparison with other European studies
    C Cedrone
    Physiopathological Optics, Department of Biopathology and Diagnostic Imaging, University of Rome Tor Vergata, Rome, Italy
    Eye (Lond) 20:661-7. 2006
  5. doi request reprint New strategies for neuroprotection in glaucoma, a disease that affects the central nervous system
    Carlo Nucci
    Ophthalmology Unit, Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome Italy Electronic address
    Eur J Pharmacol 787:119-26. 2016
  6. ncbi request reprint Ophthalmic segment of internal carotid artery aneurysm mimicking normal tension glaucoma
    Carlo Nucci
    Ophthalmology Unit, Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Via Montpelier 1, 00133, Rome, Italy
    Int Ophthalmol 36:907-914. 2016
  7. doi request reprint Links among glaucoma, neurodegenerative, and vascular diseases of the central nervous system
    Carlo Nucci
    Ophthalmology Unit, Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy Electronic address
    Prog Brain Res 221:49-65. 2015
  8. pmc Increased malondialdehyde concentration and reduced total antioxidant capacity in aqueous humor and blood samples from patients with glaucoma
    Carlo Nucci
    Ophthalmology Unit, Department of Exp Medicine and Surgery, Tor Vergata University of Rome, Italy
    Mol Vis 19:1841-6. 2013
  9. doi request reprint Glaucoma progression associated with Leber's hereditary optic neuropathy
    Carlo Nucci
    Ophthalmological Unit, Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Via Montpellier 1, Rome, Italy
    Int Ophthalmol 33:75-7. 2013
  10. doi request reprint Brain involvement in glaucoma: advanced neuroimaging for understanding and monitoring a new target for therapy
    Carlo Nucci
    Ophthalmology Unit, Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Curr Opin Pharmacol 13:128-33. 2013

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Apoptosis in the dorsal lateral geniculate nucleus after monocular deprivation involves glutamate signaling, NO production, and PARP activation
    C Nucci
    Department of Biopathology, Chair of Physiopathological Optics, University of Rome Tor Vergata, Via O Raimondo, Rome, 00173, Italy
    Biochem Biophys Res Commun 278:360-7. 2000
    ..In conclusion, during early postnatal development of the rat visual system monocular deprivation causes excitotoxic, nitric oxide-mediated, cell death in the dLGN that appears to be apoptotic and also requires activation of PARP...
  2. ncbi request reprint Neurochemical evidence to implicate elevated glutamate in the mechanisms of high intraocular pressure (IOP)-induced retinal ganglion cell death in rat
    Carlo Nucci
    Physiopathological Optics, Department of Biopathology, University of Rome Tor Vergata, Rome, Italy
    Neurotoxicology 26:935-41. 2005
    ....
  3. doi request reprint Age-specific changes in the prevalence and management of optically correctable visual impairment between 1988 and 2000: the Ponza Eye Study
    C Cedrone
    Physiopathological Optics, Department of Biopathology and Diagnostic Imaging, University of Rome Tor Vergata, Rome, Italy
    Eye (Lond) 23:522-9. 2009
    ..To obtain age-specific data on changes in the prevalence and management of optically correctable visual impairments (OCVIs) in Ponza, Italy...
  4. ncbi request reprint Prevalence of blindness and low vision in an Italian population: a comparison with other European studies
    C Cedrone
    Physiopathological Optics, Department of Biopathology and Diagnostic Imaging, University of Rome Tor Vergata, Rome, Italy
    Eye (Lond) 20:661-7. 2006
    ..The purpose of the present study was to provide age-specific estimates of the prevalence and causes of visual loss in an Italian population aged 40 years and over...
  5. doi request reprint New strategies for neuroprotection in glaucoma, a disease that affects the central nervous system
    Carlo Nucci
    Ophthalmology Unit, Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome Italy Electronic address
    Eur J Pharmacol 787:119-26. 2016
    ..Here we review the current literature on new strategies for neuroprotection in glaucoma, focusing on pharmacologic strategies to minimize RGC damage. ..
  6. ncbi request reprint Ophthalmic segment of internal carotid artery aneurysm mimicking normal tension glaucoma
    Carlo Nucci
    Ophthalmology Unit, Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Via Montpelier 1, 00133, Rome, Italy
    Int Ophthalmol 36:907-914. 2016
    ..Any atypical visual field defect not in keeping with a glaucomatous field loss should be further investigated. The ophthalmologist should thoroughly assess all signs that could lead to different diagnosis...
  7. doi request reprint Links among glaucoma, neurodegenerative, and vascular diseases of the central nervous system
    Carlo Nucci
    Ophthalmology Unit, Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy Electronic address
    Prog Brain Res 221:49-65. 2015
    ..In this review, we discuss recent evidence supporting pathological links between glaucoma and disorders of the CNS. ..
  8. pmc Increased malondialdehyde concentration and reduced total antioxidant capacity in aqueous humor and blood samples from patients with glaucoma
    Carlo Nucci
    Ophthalmology Unit, Department of Exp Medicine and Surgery, Tor Vergata University of Rome, Italy
    Mol Vis 19:1841-6. 2013
    ..To measure the adenosine triphosphate/adenosine diphosphate/adenosine monophosphate (ATP/ADP/AMP) concentration as a biomarker of the blood energy charge potential...
  9. doi request reprint Glaucoma progression associated with Leber's hereditary optic neuropathy
    Carlo Nucci
    Ophthalmological Unit, Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Via Montpellier 1, Rome, Italy
    Int Ophthalmol 33:75-7. 2013
    ..Screening for mitochondrial DNA mutations may be requested in patients with glaucoma who, despite pharmacologically controlled intraocular pressure, show rapid progression of the disease...
  10. doi request reprint Brain involvement in glaucoma: advanced neuroimaging for understanding and monitoring a new target for therapy
    Carlo Nucci
    Ophthalmology Unit, Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Curr Opin Pharmacol 13:128-33. 2013
    ..Diffusion Tensor-MRI allows the central damage associated with glaucoma to be assessed and therapeutic efficacy of novel neuroprotective interventions to be quantified...
  11. doi request reprint 3-T Diffusion tensor imaging of the optic nerve in subjects with glaucoma: correlation with GDx-VCC, HRT-III and Stratus optical coherence tomography findings
    Carlo Nucci
    Department of Experimental Medicine and Surgery, Ophthalmology Unit, University of Rome Tor Vergata, Via Montpellier 1, Rome 00133, Italy
    Br J Ophthalmol 96:976-80. 2012
    ....
  12. ncbi request reprint Association between lens opacities and mortality in the Priverno Eye Study
    Carlo Nucci
    Department of Biopathology and Diagnostic Imaging, University of Rome Tor Vergata, Via Montpellier 1, 00133, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 242:289-94. 2004
    ..The purpose of the present study was to further investigate the relationships between different types of lens opacity and patient survival...
  13. ncbi request reprint Incidence of visual loss in the Ponza Eye Study, Italy
    C Nucci
    Physiopathological Optics, Department of Biopathology and Diagnostic Imaging, University of Rome Tor Vergata, Rome, Italy
    Eye (Lond) 19:175-82. 2005
    ..To study the incidence of visual loss over a 12-year period in the survivors of an original cohort aged 40 years or older at baseline...
  14. ncbi request reprint A microbiological and confocal microscopy study documenting a slime-producing Staphylococcus epidermidis isolated from a nylon corneal suture of a patient with antibiotic-resistant endophthalmitis
    Carlo Nucci
    Cattedra di Ottica Fisiopatologia, Dipartimento di Biopatologia e Diagnostica per Immagini, Universita di Roma Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 243:951-4. 2005
    ..Microbiological and confocal microscopy studies of a nylon corneal suture revealed the presence of a slime-producing strain of Staphylococcus epidermidis...
  15. ncbi request reprint Multifaceted roles of nitric oxide in the lateral geniculate nucleus: from visual signal transduction to neuronal apoptosis
    C Nucci
    Department of Biopathology and Diagnostic Imaging, Physiopathological Optics, University of Rome Tor Vergata, Rome, Italy
    Toxicol Lett 139:163-73. 2003
    ..We believe that a better understanding of the role of NO in the LGN may contribute to discover new experimental strategies for the treatment of degenerative ophthalmic diseases...
  16. ncbi request reprint Apoptosis in the mechanisms of neuronal plasticity in the developing visual system
    C Nucci
    Physiopathological Optics, Department of Biopathology and Diagnostic Imaging, University of Roma Tor Vergata, Roma, Italy
    Eur J Ophthalmol 13:S36-43. 2003
    ....
  17. doi request reprint Potential roles of (endo)cannabinoids in the treatment of glaucoma: from intraocular pressure control to neuroprotection
    Carlo Nucci
    Ophthalmological Unit, Department of Biopathology and Diagnostic Imaging, University of Rome Tor Vergata, Rome, Italy
    Prog Brain Res 173:451-64. 2008
    ..Molecules capable of interfering with the ocular endocannabinoid system could offer valid alternatives to the treatment of this disease, based not only on the reduction of IOP but also on neuroprotection...
  18. doi request reprint Acute bilateral angle-closure glaucoma and choroidal effusion associated with acetazolamide administration after cataract surgery
    Raffaele Mancino
    Ophthalmology Unit, Tor Vergata University of Rome, Rome, Italy
    J Cataract Refract Surg 37:415-7. 2011
    ..Although extremely rare, this adverse effect should be considered in patients who develop acute bilateral angle-closure glaucoma and choroidal effusion after cataract surgery...
  19. ncbi request reprint Electro-oculography in pigment dispersion syndrome
    G L Scuderi
    Department of Surgery, Physiopathological Optics, University of Rome Tor Vergata, Italy
    Ophthalmic Res 30:23-9. 1998
    ..These results indicate primary involvement of the retinal pigment epithelium in PDS...
  20. ncbi request reprint Age-specific changes in the prevalence of best-corrected visual impairment in an italian population
    Claudio Cedrone
    Physiopathological Optics, Department of Biopathology and Diagnostic Imaging, University of Rome Tor Vergata, Rome, Italy
    Ophthalmic Epidemiol 14:320-6. 2007
    ..To investigate changes in the prevalence of visual impairment in an Italian population from 1988 to 2000...
  21. ncbi request reprint Excitotoxic mechanisms of apoptosis in the mammalian visual system following monocular visual deprivation
    Carlo Nucci
    Department of Biopathology, University of Rome Tor Vergata, Rome, Italy
    Pharmacol Toxicol 91:153-7. 2002
  22. ncbi request reprint Incidence of blindness and low vision in a sample population: the Priverno Eye Study, Italy
    Claudio Cedrone
    Physiopathological Optics, Department of Biopathology and Diagnostic Imaging, University of Rome Tor Vergata, Via Tor Vergata 135, 00133 Rome, Italy
    Ophthalmology 110:584-8. 2003
    ..To study the incidence of blindness and low vision over a 7-year period...
  23. ncbi request reprint Retinal damage caused by high intraocular pressure-induced transient ischemia is prevented by coenzyme Q10 in rat
    Carlo Nucci
    Physiopathological Optics, Department of Biopathology, University of Rome Tor Vergata 00133 Rome, Italy
    Int Rev Neurobiol 82:397-406. 2007
    ..Intraocular administration of CoQ10 minimizes glutamate increase and affords neuroprotection, suggesting that oxidative stress and energy failure might be implicated in the mechanisms of RGC death...
  24. ncbi request reprint Involvement of the endocannabinoid system in retinal damage after high intraocular pressure-induced ischemia in rats
    Carlo Nucci
    Physiopathological Optics, Department of Biopathology and Diagnostic Imaging, University of Rome Tor Vergata, Rome, Italy
    Invest Ophthalmol Vis Sci 48:2997-3004. 2007
    ....
  25. ncbi request reprint Validity and limitations of the Nidek NT-4000 non-contact tonometer: a clinical study
    Federico Regine
    Cattedra di Ottica Fisiopatologica, Dipartimento di Biopatologia e Diagnostica per Immagini, Universita degli Studi di Roma Tor Vergata, Italy
    Ophthalmic Physiol Opt 26:33-9. 2006
    ..For detection of IOPs > or =21 mmHg, NPT displayed very high sensitivity (0.90) and good specificity (0.95). NPT may be useful in screening and clinical settings but borderline-high IOP readings should be confirmed with GAT...
  26. ncbi request reprint Central serous chorioretinopathy in patients with psoriasis
    Carlo Nucci
    Acta Ophthalmol Scand 82:105-7. 2004