Alessandro Terrinoni

Summary

Affiliation: University of Rome Tor Vergata
Country: Italy

Publications

  1. pmc Severe erytrodermic psoriasis in child twins: from clinical-pathological diagnosis to treatment of choice through genetic analyses: two case reports
    Elena Campione
    Department of Dermatology, Tor Vergata University of Rome, Rome, Italy
    BMC Res Notes 7:929. 2014
  2. pmc Dermoscopy as an adjuvant tool for detecting skin leiomyomas in patient with uterine fibroids and cerebral cavernomas
    Laura Diluvio
    Department of Dermatology, University of Tor Vergata, Rome, Italy
    BMC Dermatol 14:7. 2014
  3. pmc Role of p63 and the Notch pathway in cochlea development and sensorineural deafness
    Alessandro Terrinoni
    Biochemistry Laboratory Istituto Dermopatico Dell Immacolata, c o Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, 00133 Rome, Italy
    Proc Natl Acad Sci U S A 110:7300-5. 2013
  4. doi request reprint Connexin 26 (GJB2) mutations, causing KID Syndrome, are associated with cell death due to calcium gating deregulation
    Alessandro Terrinoni
    Biochemistry Laboratory, IDI IRCCS, c o Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Biochem Biophys Res Commun 394:909-14. 2010
  5. doi request reprint Connexin 26 (GJB2) mutations as a cause of the KID syndrome with hearing loss
    Alessandro Terrinoni
    Biochemistry Laboratory, IDI IRCCS, c o Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, 00133 Rome, Italy
    Biochem Biophys Res Commun 395:25-30. 2010
  6. ncbi request reprint p63 is upstream of IKK alpha in epidermal development
    Eleonora Candi
    Biochemistry Laboratory, IDI IRCCS, University of Rome Tor Vergata, 00133 Rome, Italy
    J Cell Sci 119:4617-22. 2006
  7. pmc Scotin: A new p63 target gene expressed during epidermal differentiation
    Loredana Zocchi
    IDI IRCCS Biochemistry Laboratory, c o University of Tor Vergata, Department of Experimental Medicine, Via Montpellier 1, 00133 Rome, Italy
    Biochem Biophys Res Commun 367:271-6. 2008
  8. pmc DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2
    Eleonora Candi
    Biochemistry Laboratory, Istituto Dermopatico dell Immacolata Istituto di Ricovero e Cura a Carattere Scientifico, Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, 00133 Rome, Italy
    Proc Natl Acad Sci U S A 104:11999-2004. 2007
  9. pmc p63 regulates glutaminase 2 expression
    Arianna Giacobbe
    Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy
    Cell Cycle 12:1395-405. 2013
  10. pmc miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration
    Ivano Amelio
    Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Rome, Italy
    J Cell Biol 199:347-63. 2012

Collaborators

Detail Information

Publications22

  1. pmc Severe erytrodermic psoriasis in child twins: from clinical-pathological diagnosis to treatment of choice through genetic analyses: two case reports
    Elena Campione
    Department of Dermatology, Tor Vergata University of Rome, Rome, Italy
    BMC Res Notes 7:929. 2014
    ..The therapy should be tailored on each aetiology, if possible. The biochemical and metabolic imbalance should be corrected, and particular attention should be paid to the psychosocial behavior often related to this disfiguring disease...
  2. pmc Dermoscopy as an adjuvant tool for detecting skin leiomyomas in patient with uterine fibroids and cerebral cavernomas
    Laura Diluvio
    Department of Dermatology, University of Tor Vergata, Rome, Italy
    BMC Dermatol 14:7. 2014
    ..This can be linked to an increased risk of renal cancer in both sexes. The skin involvement is described to highlight the diagnostic role of the cutaneous counterpart in identifying this rare syndrome...
  3. pmc Role of p63 and the Notch pathway in cochlea development and sensorineural deafness
    Alessandro Terrinoni
    Biochemistry Laboratory Istituto Dermopatico Dell Immacolata, c o Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, 00133 Rome, Italy
    Proc Natl Acad Sci U S A 110:7300-5. 2013
    ....
  4. doi request reprint Connexin 26 (GJB2) mutations, causing KID Syndrome, are associated with cell death due to calcium gating deregulation
    Alessandro Terrinoni
    Biochemistry Laboratory, IDI IRCCS, c o Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Biochem Biophys Res Commun 394:909-14. 2010
    ..These results help to explain the pathogenesis of both the hearing and skin phenotypes, since calcium is also a potent regulator of the epidermal differentiation process...
  5. doi request reprint Connexin 26 (GJB2) mutations as a cause of the KID syndrome with hearing loss
    Alessandro Terrinoni
    Biochemistry Laboratory, IDI IRCCS, c o Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, 00133 Rome, Italy
    Biochem Biophys Res Commun 395:25-30. 2010
    ..We discuss the pathogenesis of both the hearing and skin phenotypes...
  6. ncbi request reprint p63 is upstream of IKK alpha in epidermal development
    Eleonora Candi
    Biochemistry Laboratory, IDI IRCCS, University of Rome Tor Vergata, 00133 Rome, Italy
    J Cell Sci 119:4617-22. 2006
    ..We also found that DeltaNp63 upregulates IKKalpha indirectly, through GATA-3. Our data are consistent with a role for p63 directly upstream of IKKalpha in epithelial development...
  7. pmc Scotin: A new p63 target gene expressed during epidermal differentiation
    Loredana Zocchi
    IDI IRCCS Biochemistry Laboratory, c o University of Tor Vergata, Department of Experimental Medicine, Via Montpellier 1, 00133 Rome, Italy
    Biochem Biophys Res Commun 367:271-6. 2008
    ..We conclude that Scotin is a new p63 target gene induced during epithelial differentiation, a complex process that also involves ER stress induction...
  8. pmc DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2
    Eleonora Candi
    Biochemistry Laboratory, Istituto Dermopatico dell Immacolata Istituto di Ricovero e Cura a Carattere Scientifico, Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, 00133 Rome, Italy
    Proc Natl Acad Sci U S A 104:11999-2004. 2007
    ..The action of DeltaNp63 is not due to a direct regulation of TEC differentiation, but it is compatible with maintenance of their "stemness," the thymic abnormalities resulting from epithelial failure due to loss of stem cells...
  9. pmc p63 regulates glutaminase 2 expression
    Arianna Giacobbe
    Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy
    Cell Cycle 12:1395-405. 2013
    ..Altogether, our findings demonstrate that GLS2 is a bona fide TAp63 target gene, and that the TAp63-dependent regulation of GLS2 is important for both physiological and pathological processes...
  10. pmc miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration
    Ivano Amelio
    Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Rome, Italy
    J Cell Biol 199:347-63. 2012
    ..Our results uncover a new regulatory pathway involving a differentiation-promoting microribonucleic acid that regulates actin adhesion dynamics in human and mouse epidermis...
  11. doi request reprint The sterile alpha-motif (SAM) domain of p63 binds in vitro monoasialoganglioside (GM1) micelles
    Stefano Rufini
    Department of Biology, University of Tor Vergata, 00133 Rome, Italy
    Biochem Pharmacol 82:1262-8. 2011
    ..Therefore, we propose a potential biological role of p63-GM1 interaction in regulation of p63 during epidermal differentiation...
  12. doi request reprint Common fragile sites in colon cancer cell lines: role of mismatch repair, RAD51 and poly(ADP-ribose) polymerase-1
    Patrizia Vernole
    Department of Public Health and Cell Biology, University of Rome Tor Vergata, Via Montpellier 1, 00133, Rome, Italy
    Mutat Res 712:40-8. 2011
    ..Our results indicate that MMR modulates colon cancer sensitivity to chromosomal breaks and CFS induced by APC and RAD51 silencing...
  13. ncbi request reprint p63 and p73, members of the p53 gene family, transactivate PKCdelta
    Raffaella Ponassi
    Biochemistry Laboratory, IDI IRCCS, c o University of Rome Tor Vergata, 00133 Rome, Italy
    Biochem Pharmacol 72:1417-22. 2006
    ..The results obtained demonstrated that, at least in vitro, the p53 family members tested (TAp63alpha, TAp73alpha, DeltaNp63alpha, but not DeltaNp73alpha) were able to drive transcription from the PKCdelta promoter...
  14. pmc Novel and recurrent ALDH3A2 mutations in Italian patients with Sjögren-Larsson syndrome
    Biagio Didona
    Dermatology Division, IDI IRCCS, Via Monti di Creta, 104, Rome, Italy
    J Hum Genet 52:865-70. 2007
    ..These results add to understanding of the genetic basis of SLS and will be useful for DNA diagnosis of this disease...
  15. doi request reprint Kaposi's sarcoma in a patient treated with imatinib mesylate for chronic myeloid leukemia
    Elena Campione
    Department of Dermatology, University of Rome Tor Vergata, Rome, Italy
    Clin Ther 31:2565-9. 2009
    ..Flare of Kaposi's sarcoma (KS) is well described in immunosuppressed patients treated with corticosteroids and rituximab, but has not yet been reported during treatment with imatinib...
  16. pmc OTX2 regulates the expression of TAp63 leading to macular and cochlear neuroepithelium development
    Ramona Palombo
    Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, 00133 Rome, Italy
    Aging (Albany NY) 7:928-36. 2015
    ..Although the abnormalities found in our patient were still at a subclinical extent, aging could exacerbate this impairment and cause a decrease in quality of life. ..
  17. ncbi request reprint Identification of the keratin K9 R162W mutation in patients of Italian origin with epidermolytic palmoplantar keratoderma
    Alessandro Terrinoni
    II Dermatological Division, Istituto Dermopatico dell Immacolata, IDI IRCCS, Rome, Italy
    Eur J Dermatol 14:375-8. 2004
    ....
  18. ncbi request reprint p73-alpha is capable of inducing scotin and ER stress
    Alessandro Terrinoni
    Biochemistry Laboratory, IDI IRCCS, Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, 00133 Rome, Italy
    Oncogene 23:3721-5. 2004
    ..This molecular mechanism might contribute to the effector events inducing apoptosis downstream of p73...
  19. doi request reprint MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1
    Rossella Menghini
    Department of Internal Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Circulation 120:1524-32. 2009
    ..miR-217 regulates the expression of silent information regulator 1 (SirT1), a major regulator of longevity and metabolic disorders that is progressively reduced in multiple tissues during aging...
  20. doi request reprint Inhibition of homologous recombination by treatment with BVDU (brivudin) or by RAD51 silencing increases chromosomal damage induced by bleomycin in mismatch repair-deficient tumour cells
    Patrizia Vernole
    Department of Public Health and Cellular Biology, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Mutat Res 664:39-47. 2009
    ..In MMR-deficient cells, BVDU attenuates the repair of BLM-induced DSBs and this is likely to occur via inhibition of HR...
  21. ncbi request reprint Involvement of the endocannabinoid system in retinal damage after high intraocular pressure-induced ischemia in rats
    Carlo Nucci
    Physiopathological Optics, Department of Biopathology and Diagnostic Imaging, University of Rome Tor Vergata, Rome, Italy
    Invest Ophthalmol Vis Sci 48:2997-3004. 2007
    ....
  22. pmc Transglutaminase 5 is regulated by guanine-adenine nucleotides
    Eleonora Candi
    Department of Experimental Medicine and Biochemical Sciences, Biochemistry LAb IDI IRCCS, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Biochem J 381:313-9. 2004
    ..Taken together, these results indicate that TGases are a complex family of enzymes regulated by calcium, with at least three of them, namely TGase2, TGase3 and TGase5, also being regulated by ATP and GTP...