Yuko Suzuki

Summary

Affiliation: Health Sciences University of Hokkaido
Country: Japan

Publications

  1. ncbi request reprint Expression of IGFBPs in the developing mouse submandibular and von Ebner's glands
    Yuko Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, 061 0293 Ishikari Tobetsu, Japan
    Anat Embryol (Berl) 211:189-96. 2006
  2. pmc Development of gustatory papillae in the absence of Six1 and Six4
    Yuko Suzuki
    Division of Biostatistics, Department of Clinical Psychology, School of Psychological Science, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    J Anat 219:710-21. 2011
  3. ncbi request reprint Expression of insulin-like growth factor family in the rat olfactory epithelium
    Yuko Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293 Japan
    Anat Embryol (Berl) 205:401-5. 2002
  4. ncbi request reprint Expression of bHLH transcription factors and IGFs in the non-sensory patches, olfactory epithelium and vomeronasal organ
    Yuko Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu 061 0293, Japan
    Chem Senses 30:i125-6. 2005
  5. ncbi request reprint Expression of bHLH transcription factors NSCL1 and NSCL2 in the mouse olfactory system
    Yuko Suzuki
    Department of Oral Histology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu 061 0293, Japan
    Chem Senses 28:603-8. 2003
  6. ncbi request reprint Expression of Hes6 and NeuroD in the olfactory epithelium, vomeronasal organ and non-sensory patches
    Yuko Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu 061 0293, Japan
    Chem Senses 28:197-205. 2003
  7. ncbi request reprint Role of IGFBPs in the morphogenesis of lingual papillae
    Yuko Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    Anat Rec A Discov Mol Cell Evol Biol 286:841-7. 2005
  8. ncbi request reprint Fine structural aspects of apoptosis in the olfactory epithelium
    Yuko Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    J Neurocytol 33:693-702. 2004
  9. ncbi request reprint Expression of NeuroD in the mouse taste buds
    Yuko Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293, Japan
    Cell Tissue Res 307:423-8. 2002
  10. ncbi request reprint A comparative study of an olfactory epithelial area lacking olfactory neurons and a nearby presence of TGF-alpha-like immunoreactive olfactory neurons
    Y Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    Anat Embryol (Berl) 203:239-47. 2001

Collaborators

Detail Information

Publications44

  1. ncbi request reprint Expression of IGFBPs in the developing mouse submandibular and von Ebner's glands
    Yuko Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, 061 0293 Ishikari Tobetsu, Japan
    Anat Embryol (Berl) 211:189-96. 2006
    ..These data support a role for these molecules as local mediators of salivary growth and differentiation...
  2. pmc Development of gustatory papillae in the absence of Six1 and Six4
    Yuko Suzuki
    Division of Biostatistics, Department of Clinical Psychology, School of Psychological Science, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    J Anat 219:710-21. 2011
    ..The foliate papillae elevated initially, and showed stunted trenches. Therefore, Six1 and Six4 function synergistically to form gustatory papillae during development of the tongue...
  3. ncbi request reprint Expression of insulin-like growth factor family in the rat olfactory epithelium
    Yuko Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293 Japan
    Anat Embryol (Berl) 205:401-5. 2002
    ..IGFBPs may modulate IGF-I activity via their production by Bowman's glands, olfactory cells, and supporting cells themselves...
  4. ncbi request reprint Expression of bHLH transcription factors and IGFs in the non-sensory patches, olfactory epithelium and vomeronasal organ
    Yuko Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu 061 0293, Japan
    Chem Senses 30:i125-6. 2005
  5. ncbi request reprint Expression of bHLH transcription factors NSCL1 and NSCL2 in the mouse olfactory system
    Yuko Suzuki
    Department of Oral Histology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu 061 0293, Japan
    Chem Senses 28:603-8. 2003
    ..Moreover, the temporal pattern of expression suggests that NSCL1 and NSCL2 may function during development rather than in the adult stage...
  6. ncbi request reprint Expression of Hes6 and NeuroD in the olfactory epithelium, vomeronasal organ and non-sensory patches
    Yuko Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu 061 0293, Japan
    Chem Senses 28:197-205. 2003
    ..At P3-P7, expression of NeuroD and Hes6 disappeared in the region corresponding to the presumptive non-sensory patches. The loss of these genes may stop the differentiation and may cause apoptosis of GBCs and ORNs...
  7. ncbi request reprint Role of IGFBPs in the morphogenesis of lingual papillae
    Yuko Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    Anat Rec A Discov Mol Cell Evol Biol 286:841-7. 2005
    ..As previously suggested from a study on postnatal mice (Suzuki et al. J Comp Neurol 2005;482:74-84), IGFBP-4 acts in the epithelial invagination to form the trenches, grooves, or furrows of lingual papillae during development...
  8. ncbi request reprint Fine structural aspects of apoptosis in the olfactory epithelium
    Yuko Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    J Neurocytol 33:693-702. 2004
    ....
  9. ncbi request reprint Expression of NeuroD in the mouse taste buds
    Yuko Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293, Japan
    Cell Tissue Res 307:423-8. 2002
    ..These results suggest that NeuroD is expressed in a mature cell type, type-II cells, but not in type-III cells...
  10. ncbi request reprint A comparative study of an olfactory epithelial area lacking olfactory neurons and a nearby presence of TGF-alpha-like immunoreactive olfactory neurons
    Y Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    Anat Embryol (Berl) 203:239-47. 2001
    ..Three-dimensional analysis of double-labeled (TGF-alpha, PGP9.5) serial sections revealed a unique relation among the epithelial patches, TGF-alpha-like immunoreactive neurons and olfactory epithelium...
  11. ncbi request reprint Olfactory epithelium consisting of supporting cells and horizontal basal cells in the posterior nasal cavity of mice
    Y Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    Cell Tissue Res 299:313-25. 2000
    ..This suggests that the epithelium consisting of supporting cells and horizontal basal cells is generated by the apoptotic death of olfactory cells and globose basal cells during postnatal development...
  12. doi request reprint Expression of Sox2 in mouse taste buds and its relation to innervation
    Yuko Suzuki
    Division of Histology, Department of Oral Growth and Development, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    Cell Tissue Res 332:393-401. 2008
    ..Sox2-IR cells were found in the populations of basal cells and of immature and some mature taste bud cells. A large number of Sox2-IR cells were identified as type-I cells, with a few being type-II and type-III cells...
  13. ncbi request reprint Detection of neurotrophic factors in taste buds by laser capture microdissection, immunohistochemistry, and in situ hybridization
    Yuko Suzuki
    Division of Histology, Department of Oral Growth and Development, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    Arch Histol Cytol 70:117-26. 2007
    ..In summary, LCM is a useful tool for the detection of a relatively small amount of mRNA, such as that of neurotrophic factors and receptors in the taste buds...
  14. ncbi request reprint Apoptosis and the insulin-like growth factor family in the developing olfactory epithelium
    Yuko Suzuki
    Division of Histology, Department of Oral Growth and Development, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    Anat Sci Int 82:200-6. 2007
    ..In this review article, we focus on apoptosis, IGF, and their related molecules in the developing olfactory epithelium...
  15. doi request reprint Regulatory role of Six1 in the development of taste papillae
    Yuko Suzuki
    Department of Oral Growth and Development, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    Cell Tissue Res 339:513-25. 2010
    ..Thus, the modulation of signaling events in Six1 ( -/- ) leads to the earlier formation of the gustatory papillae, the abnormal distribution of fungiform papillae, and malformed trenches in circumvallate and foliate papillae...
  16. doi request reprint Expression of Six1 and Six4 in mouse taste buds
    Yuko Suzuki
    Division of Histology, Department of Oral Growth and Development, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu 061 0293, Japan
    J Mol Histol 41:205-14. 2010
    ..These results suggest that Six1 and Six4 genes are expressed in the taste bud cells, in newly formed or surviving type-II cells...
  17. ncbi request reprint Expression of glial cell line-derived neurotrophic factor (GDNF) and GDNF family receptor alpha1 in mouse taste bud cells after denervation
    Masako Takeda
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Ishikari, Hokkaido, Japan
    Anat Sci Int 80:105-10. 2005
    ..Thus, GDNF- and GFRalpha1-immunoreactive taste bud cells after denervation vanished following the disappearance of the taste buds and reappeared at the same time as the taste buds reappeared...
  18. ncbi request reprint Expression of GDNF and GFR alpha 1 in mouse taste bud cells
    Masako Takeda
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Ishikari, Hokkaido 061 0293, Japan
    J Comp Neurol 479:94-102. 2004
    ..We conclude that GDNF in the type-II cells may exert trophic actions on type-I, -II, and -III taste bud cells by binding to their GFR alpha 1 receptors...
  19. ncbi request reprint Expression of neural cell-adhesion molecule mRNA during mouse molar tooth development
    Nobuko Obara
    Department of Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido, Japan
    Arch Oral Biol 47:805-13. 2002
    ..This study newly identifies the dental papilla and the stratum intermedium as NCAM-expressing sites...
  20. ncbi request reprint Gene expression of beta-catenin is up-regulated in inner dental epithelium and enamel knots during molar tooth morphogenesis in the mouse
    Nobuko Obara
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari Tobetsu, Hokkaido 061 0293, Japan
    Cell Tissue Res 325:197-201. 2006
    ..These findings raise the possibility that the up-regulation of the gene expression and the stabilization of the protein by Wnt signaling play a role in the regulation of the activities of beta-catenin in tooth morphogenesis...
  21. ncbi request reprint Expression of BDNF and TrkB in mouse taste buds after denervation and in circumvallate papillae during development
    Nobuhiko Uchida
    Department of Oral Surgery, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Hokkaido, Japan
    Arch Histol Cytol 66:17-25. 2003
    ....
  22. ncbi request reprint Distinct expression pattern of insulin-like growth factor family in rodent taste buds
    Yuko Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu 061 0293, Japan
    J Comp Neurol 482:74-84. 2005
    ..The activity of these IGFs may be modulated through their interaction with IGFBP-2, -5, and 6...
  23. ncbi request reprint Immunohistochemical detection of neurotrophin-3 and -4, and their receptors in mouse taste bud cells
    Masako Takeda
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Ishikari, Hokkaido 061 0293, Japan
    Arch Histol Cytol 68:393-403. 2005
    ..5 and gustducin. We conclude that NT4 may exert trophic actions on all types of taste bud cells by binding to their TrkB receptors, and NT3 may also have a similar, though negligible role...
  24. ncbi request reprint Immunofluorescence detection of cadherins in mouse tooth germs during root development
    N Obara
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    Arch Oral Biol 44:415-21. 1999
    ..These results suggest that the two cadherins play a part in root as well as in crown development, and indicate that the decrease in the amount of these molecules and the fragmentation of the epithelial root sheath are interrelated...
  25. ncbi request reprint Induction of apoptosis by colchicine in taste bud and epithelial cells of the mouse circumvallate papillae
    M Takeda
    Department of Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Ishikari, Hokkaido 061 0293, Japan
    Cell Tissue Res 302:391-5. 2000
    ..These results indicate that colchicine treatment of mice induces the apoptosis of taste bud and epithelial cells in the circumvallate papillae and dorsal epithelial cells around the circumvallate papillae...
  26. ncbi request reprint Colchicine-induced cell death and proliferation in the olfactory epithelium and vomeronasal organ of the mouse
    Y Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    Anat Embryol (Berl) 198:43-51. 1998
    ..In the next month, these regions became normal olfactory epithelium. This suggests that the globose basal cells in the surrounding normal olfactory epithelium might invade these regions to give rise to the olfactory cells...
  27. ncbi request reprint Bulbectomy of neonatal mice induces migration of basal cells from the olfactory epithelium
    Y Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    Brain Res Dev Brain Res 108:295-8. 1998
    ..At 1 month, not only basal cells but also olfactory cells and presumed supporting cells were involved in the clusters in the lamina propria and olfactory bulb, suggesting that migrated cells do not transform to other phenotypes...
  28. ncbi request reprint Effect of denervation on lymphocytes and dendritic cells in the rat circumvallate and foliate papillae
    Y Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    Anat Embryol (Berl) 196:447-55. 1997
    ..The finding suggests that gammadelta T lymphocytes and dendritic cells in the rat circumvallate and foliate papillae interact with each other to respond to changes such as the presence or absence of taste buds in the epithelium...
  29. ncbi request reprint Cell death, phagocytosis, and neurogenesis in mouse olfactory epithelium and vomeronasal organ after colchicine treatment
    Y Suzuki
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Japan
    Ann N Y Acad Sci 855:252-4. 1998
    ....
  30. doi request reprint Expression of functional Stim1-mKO1 in rat submandibular acinar cells by retrograde ductal injection of an adenoviral vector
    Takao Morita
    Department of Pharmacology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293, Japan
    Arch Oral Biol 56:1356-65. 2011
    ....
  31. ncbi request reprint Expression of E- and P-cadherin during tooth morphogenesis and cytodifferentiation of ameloblasts
    N Obara
    Department of Oral Anatomy, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    Anat Embryol (Berl) 197:469-75. 1998
    ....
  32. ncbi request reprint Age-dependent neurodegeneration accompanying memory loss in transgenic mice defective in mitochondrial aldehyde dehydrogenase 2 activity
    Ikuroh Ohsawa
    Department of Biochemistry and Cell Biology, Institute of Development and Aging Sciences, Graduate School of Medicine, Nippon Medical School, Kawasaki 211 8533, Japan
    J Neurosci 28:6239-49. 2008
    ....
  33. ncbi request reprint Characterization of electro-olfactogram oscillations and their computational reconstruction
    Noriyo Suzuki
    Animal Behavior and Intelligence, Division of Biological Sciences, Graduate School of Science, Hokkaido University, Sapporo 060 0810, Japan
    Chem Senses 29:411-24. 2004
    ..The simulation program for Macintosh ('oscillation 3.2.4' for MacOS 8.6 or later) is available on the world wide web (http://bio2.sci.hokudai.ac.jp/bio/chinou1/noriyo_home.html)...
  34. ncbi request reprint Notch2 is required for formation of the placental circulatory system, but not for cell-type specification in the developing mouse placenta
    Yoshio Hamada
    National Institute for Basic Biology, Okazaki, Aichi 444 8585, Japan
    Differentiation 75:268-78. 2007
    ..Thus, Notch2 is not cell autonomously required for the early cell fate determination of subtypes of trophoblast cells, but plays an indispensable role in the formation of maternal blood sinuses in the developing mouse placenta...
  35. doi request reprint Characterization of plant XRCC1 and its interaction with proliferating cell nuclear antigen
    Yukinobu Uchiyama
    Department of Applied Biological Science, Tokyo University of Science, Chiba, 278 8510, Japan
    Planta 227:1233-41. 2008
    ..Bleomycin also increased the fraction of OsXRCC1 associated with chromatin. These results suggest that OsXRCC1 contributes to DNA repair pathways that differ from the mammalian BER system...
  36. ncbi request reprint The effects of phthalate esters on the tryptophan-niacin metabolism
    Tsutomu Fukuwatari
    Laboratories of Food Science and Nutrition, Department of Life Style Studies, School of Human Cultures, The University of Shiga Prefecture, Hikone, Shiga 522 8533, Japan
    Adv Exp Med Biol 527:659-64. 2003
    ..We conclude that PhE such as DEHP and DBP disturbed the Tryptophan-niacin metabolism...
  37. doi request reprint Disappearance of the angiogenic potential of endothelial cells caused by Argonaute2 knockdown
    Tomohiro Asai
    Department of Medical Biochemistry and Global COE, University of Shizuoka School of Pharmaceutical Sciences, 52 1 Yada, Suruga ku, Shizuoka 422 8526, Japan
    Biochem Biophys Res Commun 368:243-8. 2008
    ..These present data demonstrate that siAgo2 inhibited indispensable events of angiogenesis in vitro. This is the first report suggesting that Ago2 is required for angiogenesis...
  38. ncbi request reprint Glucagon-like peptide 1 activates protein kinase C through Ca2+-dependent activation of phospholipase C in insulin-secreting cells
    Yuko Suzuki
    Department of Physiology, Hamamatsu University School of Medicine, 1 20 1 Handayama, Hamamatsu 431 3192, Japan
    J Biol Chem 281:28499-507. 2006
    ..Thus, GLP-1 can activate PKCalpha and PKCepsilon, and these GLP-1-activated PKCs may contribute considerably to insulin secretion at a substimulatory concentration of glucose...
  39. ncbi request reprint Nafamostat attenuated the impairment of fibrinolysis in animal sepsis model by suppressing the increase of plasminogen activator inhibitor type 1
    Tomasz Hryszko
    Department of Physiology, Hamamatsu University School of Medicine, Handa yama, Japan
    J Trauma 60:859-64. 2006
    ..We analyzed therapeutic advantage of nafamostat, a broad-range protease inhibitor, on fibrinolysis in an animal sepsis model...
  40. pmc Bimodal role of conventional protein kinase C in insulin secretion from rat pancreatic beta cells
    Hui Zhang
    Institute for Molecular and Cellular Regulation, Gunma University, Maebashi 371 8512, Japan
    J Physiol 561:133-47. 2004
    ..Conventional PKC is inhibitory on depolarization-induced insulin secretion per se, but it also augments glucose-induced secretion...
  41. ncbi request reprint Vacuolating cytotoxin A is associated with increased thrombin generation in gastric mucosa
    Yuko Suzuki
    Department of Internal Medicine, Division of Gastroenterology and Hepatology, Mie University School of Medicine, Edobashi 2 174, Tsu City, Mie 514 8507, Japan
    Helicobacter 10:323-31. 2005
    ..The present study was undertaken to assess in vivo the relationship between gastric intramucosal generation of thrombin and Helicobacter pylori infection...
  42. ncbi request reprint Dose-dependent suppression of tea catechins with a galloyl moiety on postprandial hypertriglyceridemia in rats
    Yuko Suzuki
    Central Research Institute, ITO EN, Ltd, Shizuoka 421 0516, Japan
    Biosci Biotechnol Biochem 69:1288-91. 2005
    ..These results strongly suggest that catechins with a galloyl moiety would be promising agents for suppressing dietary fat absorption through the small intestine...
  43. ncbi request reprint Tea catechins with a galloyl moiety suppress postprandial hypertriacylglycerolemia by delaying lymphatic transport of dietary fat in rats
    Ikuo Ikeda
    Laboratory of Nutrition Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School of Kyushu University, Fukuoka 812 8581, Japan
    J Nutr 135:155-9. 2005
    ..Because postprandial hypertriacylglycerolemia is a risk factor for coronary heart disease, our results suggest that catechins with a galloyl moiety may prevent this disease...
  44. ncbi request reprint Novel embryonic stem cells expressing tdKaede protein photoconvertible from green to red fluorescence
    Yoko Shigematsu
    Laboratory Animal Resource Center, University of Tsukuba, Tsukuba, Ibaraki 305 8575, Japan
    Int J Mol Med 20:439-44. 2007
    ..These novel ES cell lines ubiquitously expressing photoconvertible Kaede protein, B6KED-1 and -2, are useful for basic research in developmental biology and regenerative medicine...