Ken Arita

Summary

Affiliation: Hokkaido University
Country: Japan

Publications

  1. ncbi Patients with recessive dystrophic epidermolysis bullosa develop squamous-cell carcinoma regardless of type VII collagen expression
    Celine Pourreyron
    Centre for Cutaneous Research, Institute of Cell and Molecular Science, Barts and The London, Queen Mary University of London, Whitechapel, London, UK
    J Invest Dermatol 127:2438-44. 2007
  2. pmc A novel N14Y mutation in Connexin26 in keratitis-ichthyosis-deafness syndrome: analyses of altered gap junctional communication and molecular structure of N terminus of mutated Connexin26
    Ken Arita
    Department of Dermatology, Hokkaido University Graduate School of Medicine, North 15 West 7, Kita ku, Sapporo 060 8638, Japan
    Am J Pathol 169:416-23. 2006
  3. ncbi Changes in gap junction distribution and connexin expression pattern during human fetal skin development
    Ken Arita
    Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    J Histochem Cytochem 50:1493-500. 2002
  4. ncbi Erythrokeratoderma variabilis without connexin 31 or connexin 30.3 gene mutation: immunohistological, ultrastructural and genetic studies
    Ken Arita
    Department of Dermatology, Hokkaido University Graduate School of Medicine, North 15 West 7, Kita ku, Sapporo 060 8638, Japan
    Acta Derm Venereol 83:266-70. 2003
  5. pmc Plectin deficiency leads to both muscular dystrophy and pyloric atresia in epidermolysis bullosa simplex
    Ken Natsuga
    Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Hum Mutat 31:E1687-98. 2010
  6. pmc Mutations in lipid transporter ABCA12 in harlequin ichthyosis and functional recovery by corrective gene transfer
    Masashi Akiyama
    Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    J Clin Invest 115:1777-84. 2005
  7. ncbi Changing pattern of deiminated proteins in developing human epidermis
    Yukiko Tsuji
    Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    J Invest Dermatol 120:817-22. 2003
  8. doi Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA-PLA1alpha in autosomal recessive hypotrichosis
    Satoru Shinkuma
    Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Hum Mutat 31:602-10. 2010
  9. pmc Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis
    Ken Arita
    Genetic Skin Disease Group, St John s Institute of Dermatology, Division of Genetics and Molecular Medicine, The Guy s, King s College and St Thomas School of Medicine, London SE1 9RT, UK
    Am J Hum Genet 82:73-80. 2008
  10. ncbi Genetic diseases of junctions
    Joey E Lai-Cheong
    King s College London, The Guy s, King s College and St Thomas School of Medicine, Genetic Skin Disease Group, Division of Genetics and Molecular Medicine, St John s Institute of Dermatology, London, UK
    J Invest Dermatol 127:2713-25. 2007

Collaborators

Detail Information

Publications16

  1. ncbi Patients with recessive dystrophic epidermolysis bullosa develop squamous-cell carcinoma regardless of type VII collagen expression
    Celine Pourreyron
    Centre for Cutaneous Research, Institute of Cell and Molecular Science, Barts and The London, Queen Mary University of London, Whitechapel, London, UK
    J Invest Dermatol 127:2438-44. 2007
    ..These data suggest that individuals with RDEB can develop SCC regardless of type VII collagen expression and that additional factors have a role in explaining the high incidence of tumors complicating this genodermatosis...
  2. pmc A novel N14Y mutation in Connexin26 in keratitis-ichthyosis-deafness syndrome: analyses of altered gap junctional communication and molecular structure of N terminus of mutated Connexin26
    Ken Arita
    Department of Dermatology, Hokkaido University Graduate School of Medicine, North 15 West 7, Kita ku, Sapporo 060 8638, Japan
    Am J Pathol 169:416-23. 2006
    ....
  3. ncbi Changes in gap junction distribution and connexin expression pattern during human fetal skin development
    Ken Arita
    Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    J Histochem Cytochem 50:1493-500. 2002
    ..Furthermore, the changing patterns of connexin expression suggest that Cx26 is important for early fetal epidermal development...
  4. ncbi Erythrokeratoderma variabilis without connexin 31 or connexin 30.3 gene mutation: immunohistological, ultrastructural and genetic studies
    Ken Arita
    Department of Dermatology, Hokkaido University Graduate School of Medicine, North 15 West 7, Kita ku, Sapporo 060 8638, Japan
    Acta Derm Venereol 83:266-70. 2003
    ..1 genes in this patient. The results indicate that erythrokeratoderma variabilis is pathologically heterogeneous, and that abnormalities in keratinization other than Cx30.3 and 31 gene mutations may underlie some forms of this disease...
  5. pmc Plectin deficiency leads to both muscular dystrophy and pyloric atresia in epidermolysis bullosa simplex
    Ken Natsuga
    Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Hum Mutat 31:E1687-98. 2010
    ..This study demonstrates that plectin deficiency can indeed lead to both muscular dystrophy and pyloric atresia in an individual EBS patient...
  6. pmc Mutations in lipid transporter ABCA12 in harlequin ichthyosis and functional recovery by corrective gene transfer
    Masashi Akiyama
    Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    J Clin Invest 115:1777-84. 2005
    ..Our findings not only allow DNA-based early prenatal diagnosis but also suggest the possibility of gene therapy for HI...
  7. ncbi Changing pattern of deiminated proteins in developing human epidermis
    Yukiko Tsuji
    Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    J Invest Dermatol 120:817-22. 2003
    ..These results demonstrate an orderly formation of deiminated proteins in different layers of embryonic epidermis and suggest important roles for peptidylarginine deiminases in human epidermal morphogenesis...
  8. doi Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA-PLA1alpha in autosomal recessive hypotrichosis
    Satoru Shinkuma
    Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Hum Mutat 31:602-10. 2010
    ..These results suggest defective activation of P2Y5 due to reduced 2-acyl lysophosphatidic acid production by the mutant PA-PLA(1)alpha is involved in the pathogenesis of ARH...
  9. pmc Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis
    Ken Arita
    Genetic Skin Disease Group, St John s Institute of Dermatology, Division of Genetics and Molecular Medicine, The Guy s, King s College and St Thomas School of Medicine, London SE1 9RT, UK
    Am J Hum Genet 82:73-80. 2008
    ....
  10. ncbi Genetic diseases of junctions
    Joey E Lai-Cheong
    King s College London, The Guy s, King s College and St Thomas School of Medicine, Genetic Skin Disease Group, Division of Genetics and Molecular Medicine, St John s Institute of Dermatology, London, UK
    J Invest Dermatol 127:2713-25. 2007
    ..However, this review focuses mainly on inherited disorders of junctions that have an abnormal skin phenotype...
  11. ncbi Novel ABCA12 mutations identified in two cases of non-bullous congenital ichthyosiform erythroderma associated with multiple skin malignant neoplasia
    Ken Natsuga
    J Invest Dermatol 127:2669-73. 2007
  12. ncbi Focal dermal hypoplasia resulting from a new nonsense mutation, p.E300X, in the PORCN gene
    Suzanne E Clements
    St John s Institute of Dermatology, Division of Genetics and Molecular Medicine, The Guy s, King s College, St Thomas School of Medicine, Guy s Hospital, London Bridge, London, UK
    J Dermatol Sci 49:39-42. 2008
    ..The molecular basis of FDH involves mutations in the PORCN gene, which encodes an enzyme that allows membrane targeting and secretion of several Wnt proteins critical for normal tissue development...
  13. pmc Human bullous pemphigoid antigen 2 transgenic skin elicits specific IgG in wild-type mice
    Edit B Olasz
    Department of Dermatology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    J Invest Dermatol 127:2807-17. 2007
    ....
  14. ncbi Five new homozygous mutations in the KIND1 gene in Kindler syndrome
    Joey E Lai-Cheong
    J Invest Dermatol 127:2268-70. 2007
  15. ncbi A novel GJB2 mutation p.Asn54His in a patient with palmoplantar keratoderma, sensorineural hearing loss and knuckle pads
    Masashi Akiyama
    J Invest Dermatol 127:1540-3. 2007
  16. ncbi The South African "bathing suit ichthyosis" is a form of lamellar ichthyosis caused by a homozygous missense mutation, p.R315L, in transglutaminase 1
    Ken Arita
    J Invest Dermatol 127:490-3. 2007