Gen Kobashi

Summary

Affiliation: Hokkaido University
Country: Japan

Publications

  1. ncbi Association of a variant of the angiotensinogen gene with pure type of hypertension in pregnancy in the Japanese: implication of a racial difference and significance of an age factor
    G Kobashi
    Department of Public Health, Hokkaido University, Sapporo, Japan
    Am J Med Genet 86:232-6. 1999
  2. ncbi Absence of association between a common mutation in the methylenetetrahydrofolate reductase gene and preeclampsia in Japanese women
    G Kobashi
    Department of Public Health, Hokkaido University School of Medicine, Sapporo, Japan
    Am J Med Genet 93:122-5. 2000
  3. ncbi Genetic and environmental factors associated with the development of hypertension in pregnancy
    Gen Kobashi
    Department of Health for Senior Citizens, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    J Epidemiol 16:1-8. 2006
  4. ncbi Insertion/deletion polymorphism of the angiotensin-converting enzyme gene and preeclampsia in Japanese patients
    Gen Kobashi
    Division of Preventive Medicine, Department of Obstetrics and Gynecology, Hokkaido University School of Medicine, Sapporo, Japan
    Semin Thromb Hemost 31:346-50. 2005
  5. ncbi The egogram is a potent, independent risk factor for hypertension in pregnancy
    Gen Kobashi
    Assistant Professor, Hokkaido University School of Medicine, Sapporo, Japan
    Semin Thromb Hemost 31:302-6. 2005
  6. ncbi Multivariate analysis of genetic and acquired factors; T235 variant of the angiotensinogen gene is a potent independent risk factor for preeclampsia
    G Kobashi
    Department of Preventive Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Semin Thromb Hemost 27:143-7. 2001
  7. ncbi MTHFR C677T Polymorphism and factor V Leiden mutation are not associated with recurrent spontaneous abortion of unexplained etiology in Japanese women
    Gen Kobashi
    Assistant Professor, Hokkaido University Graduate School of Medicine, Sapporo 060 8638, Japan
    Semin Thromb Hemost 31:266-71. 2005
  8. ncbi High body mass index after age 20 and diabetes mellitus are independent risk factors for ossification of the posterior longitudinal ligament of the spine in Japanese subjects: a case-control study in multiple hospitals
    Gen Kobashi
    Department of Health for Senior Citizens, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Spine (Phila Pa 1976) 29:1006-10. 2004
  9. ncbi A1166C variant of angiotensin II type 1 receptor gene is associated with severe hypertension in pregnancy independently of T235 variant of angiotensinogen gene
    Gen Kobashi
    Division of Preventive Medicine, Hokkaido University Graduate School of Medicine, N15 W7, Sapporo 060 8638, Japan
    J Hum Genet 49:182-6. 2004
  10. ncbi An association between maternal smoking and preeclampsia in Japanese women
    Gen Kobashi
    Division of Preventive Medicine, Hokkaido University Graduate School of Medicine, N15W7, Kita ku, Sapporo 060 8638, Japan
    Semin Thromb Hemost 28:507-10. 2002

Detail Information

Publications55

  1. ncbi Association of a variant of the angiotensinogen gene with pure type of hypertension in pregnancy in the Japanese: implication of a racial difference and significance of an age factor
    G Kobashi
    Department of Public Health, Hokkaido University, Sapporo, Japan
    Am J Med Genet 86:232-6. 1999
    ..77, P < 0.05) or in normal controls of age 20-34 years (0.76, P < 0.001). The result indicates that the AGT variant plays a significant role in hypertension in the age group 20-34 years...
  2. ncbi Absence of association between a common mutation in the methylenetetrahydrofolate reductase gene and preeclampsia in Japanese women
    G Kobashi
    Department of Public Health, Hokkaido University School of Medicine, Sapporo, Japan
    Am J Med Genet 93:122-5. 2000
    ..38, 15%), PE without TT of AGT (0.38, 15%), and controls (0.38, 15%). The results indicate that T677 of MTHFR may not be a risk factor for PE in Japanese population...
  3. ncbi Genetic and environmental factors associated with the development of hypertension in pregnancy
    Gen Kobashi
    Department of Health for Senior Citizens, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    J Epidemiol 16:1-8. 2006
    ..Through further exploration of the risk factors associated with HP, we hope to provide useful suggestions about the development of new and effective preventive measures for a range of multifactorial diseases...
  4. ncbi Insertion/deletion polymorphism of the angiotensin-converting enzyme gene and preeclampsia in Japanese patients
    Gen Kobashi
    Division of Preventive Medicine, Department of Obstetrics and Gynecology, Hokkaido University School of Medicine, Sapporo, Japan
    Semin Thromb Hemost 31:346-50. 2005
    ..Additional studies using a larger number of patients and analyses that include other genetic and environmental factors will be necessary to confirm these results...
  5. ncbi The egogram is a potent, independent risk factor for hypertension in pregnancy
    Gen Kobashi
    Assistant Professor, Hokkaido University School of Medicine, Sapporo, Japan
    Semin Thromb Hemost 31:302-6. 2005
    ..The odds ratios were 2.2, 2.8, 4.0, and 2.5, respectively. The present results suggest that a low FC score and a high AC score may be potent, independent risk factors for HP...
  6. ncbi Multivariate analysis of genetic and acquired factors; T235 variant of the angiotensinogen gene is a potent independent risk factor for preeclampsia
    G Kobashi
    Department of Preventive Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Semin Thromb Hemost 27:143-7. 2001
    ..2, 2.5, 3.0 and 2.6, respectively, in a multiple logistic model. Our results support the concept that T235 of the angiotensinogen gene is a potent, independent risk factor for preeclampsia, as well as other lifestyle-related risk factors...
  7. ncbi MTHFR C677T Polymorphism and factor V Leiden mutation are not associated with recurrent spontaneous abortion of unexplained etiology in Japanese women
    Gen Kobashi
    Assistant Professor, Hokkaido University Graduate School of Medicine, Sapporo 060 8638, Japan
    Semin Thromb Hemost 31:266-71. 2005
    ..0% and 16.7%, respectively. In addition, no Leiden mutation of FV was detected in the women with RSA or the controls. Neither T677 of the MTHFR nor the Leiden mutation of FV was associated with unexplained RSA in the Japanese population...
  8. ncbi High body mass index after age 20 and diabetes mellitus are independent risk factors for ossification of the posterior longitudinal ligament of the spine in Japanese subjects: a case-control study in multiple hospitals
    Gen Kobashi
    Department of Health for Senior Citizens, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Spine (Phila Pa 1976) 29:1006-10. 2004
    ..A sex- and age-matched case-control study was carried out...
  9. ncbi A1166C variant of angiotensin II type 1 receptor gene is associated with severe hypertension in pregnancy independently of T235 variant of angiotensinogen gene
    Gen Kobashi
    Division of Preventive Medicine, Hokkaido University Graduate School of Medicine, N15 W7, Sapporo 060 8638, Japan
    J Hum Genet 49:182-6. 2004
    ..The present results suggest that the C1166 allele of the AT1 gene may be concerned with the predisposition to essential hypertension independently of the T235 allele of the AGT gene...
  10. ncbi An association between maternal smoking and preeclampsia in Japanese women
    Gen Kobashi
    Division of Preventive Medicine, Hokkaido University Graduate School of Medicine, N15W7, Kita ku, Sapporo 060 8638, Japan
    Semin Thromb Hemost 28:507-10. 2002
    ....
  11. ncbi Endothelial nitric oxide synthase gene (NOS3) variant and hypertension in pregnancy
    G Kobashi
    Department of Preventive Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Am J Med Genet 103:241-4. 2001
    ..The odds ratios of the factors were 2.7, 2.3, 2.2, and 2.1, respectively. Our results suggested that the Asp298 of NOS3 is a potent, independent risk factor for HP...
  12. ncbi The M235T variant of the angiotensinogen gene and the body mass index are useful markers for prevention of hypertension in pregnancy: a tree-based analysis of gene-environment interaction
    Gen Kobashi
    Division of Preventive Medicine, Hokkaido University Graduate School of Medicine, N15W7, Sapporo 060 8638, Japan
    Semin Thromb Hemost 28:501-6. 2002
    ..Determination of factors obvious before pregnancy, such as genotype or prepregnancy BMI, may be useful for devising effective individualized strategies for preventing HP...
  13. doi Cigarette smoking, STAT4 and TNFRSF1B polymorphisms, and systemic lupus erythematosus in a Japanese population
    Chikako Kiyohara
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    J Rheumatol 36:2195-203. 2009
    ..Along with environmental factors such as smoking, both polymorphisms may modulate an individual's susceptibility to SLE. We investigated these relationships in a case-control study to evaluate risk factors for SLE among Japanese women...
  14. ncbi Association between a variant of the glutathione S-transferase P1 gene (GSTP1) and hypertension in pregnancy in Japanese: interaction with parity, age, and genetic factors
    Kaori Ohta
    Department of Health for Senior Citizens, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Semin Thromb Hemost 29:653-9. 2003
    ..05). These results suggest that this variant of the GSTP1 may play a role in the manifestation of HP together with other independently and/or synergistically acting factors, particularly in primiparous pregnancy...
  15. ncbi Sleeping habit and other life styles in the prime of life and risk for ossification of the posterior longitudinal ligament of the spine (OPLL): a case-control study in Japan
    Masakazu Washio
    Department of Public Health, Sapporo Medical University School of Medicine, South 1 West 17, Sapporo City, Hokkaido 060 8556, Japan
    J Epidemiol 14:168-73. 2004
    ..However, there is little information about the relationship between OPLL and life styles in the prime of life (between 30 and 50 years)...
  16. doi Lifestyle factors and risk of amyotrophic lateral sclerosis: a case-control study in Japan
    Kazushi Okamoto
    Department of Public Health, Aichi Prefectural College of Nursing and Health, Kamishidami, Nagoya, Japan
    Ann Epidemiol 19:359-64. 2009
    ..We examined the associations between lifestyle factors and the risk of amyotrophic lateral sclerosis (ALS) using a case-control study in Aichi Prefecture, Japan...
  17. ncbi Case-control study of medical history and idiopathic pulmonary fibrosis in Japan
    Yoshihiro Miyake
    Department of Public Health, Fukuoka University School of Medicine, Fukuoka, Japan
    Respirology 10:504-9. 2005
    ..A relationship between a history of selected disorders and the risk of IPF was assessed in a multicentre hospital-based case-control study in Japan...
  18. ncbi Occupational and environmental factors and idiopathic pulmonary fibrosis in Japan
    Yoshihiro Miyake
    Department of Public Health, Fukuoka University School of Medicine, Fukuoka, Japan
    Ann Occup Hyg 49:259-65. 2005
    ..23; 95% CI = 1.01-10.84). Our results appear to confirm data from previous epidemiologic studies. Metal dust exposure may be a particularly important risk factor for IPF...
  19. doi Cigarette smoking, alcohol consumption, and risk of systemic lupus erythematosus: a case-control study in a Japanese population
    Chikako Kiyohara
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    J Rheumatol 39:1363-70. 2012
    ..Cigarette smoking may be associated with increased risk of systemic lupus erythematosus (SLE), whereas the role of alcohol consumption is unknown. We examined the association between SLE risk and smoking or drinking...
  20. ncbi Dietary habits and risk of ossification of the posterior longitudinal ligaments of the spine (OPLL); findings from a case-control study in Japan
    Kazushi Okamoto
    Department of Public Health, Aichi Prefectural College of Nursing and Health, Nagoya, Togoku, Kamishidami, Moriyama ku, Japan
    J Bone Miner Metab 22:612-7. 2004
    ..Our findings suggest that dietary habits may constitute independent risk factors for OPLL. Further studies will be needed to prospectively determine the relationship between dietary habits and OPLL risk...
  21. ncbi Nutritional status and risk of amyotrophic lateral sclerosis in Japan
    Kazushi Okamoto
    Department of Public Health, Aichi Prefectural College of Nursing and Health, Nagoya, Japan
    Amyotroph Lateral Scler 8:300-4. 2007
    ..58 (95%CI 0.40-0.96) for polyunsaturated fatty acids (PUFAs). Our findings suggest that high intakes of carbohydrate and low intakes of fat and some kinds of fatty acids may, when combined, increased the risk of ALS...
  22. doi Anti-beta2 glycoprotein-I antibody increases the risk of pregnancy-induced hypertension: a case-controlled study
    Hideto Yamada
    Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Chuo Ku, Kobe, Japan
    J Reprod Immunol 84:95-9. 2010
    ..The usefulness of anti-beta2GPI measurement among women without other anti-phospholipid antibodies requires further study...
  23. doi Cigarette smoking, N-acetyltransferase 2 polymorphisms and systemic lupus erythematosus in a Japanese population
    C Kiyohara
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Lupus 18:630-8. 2009
    ..50, 95% CI = 0.12-0.88), compared with the NAT2 rapid acetylator genotype and no history of smoking. This study suggests that, in this Japanese population, the NAT2 slow acetylator status may be a determinant in susceptibility to SLE...
  24. ncbi Descriptive epidemiology of amyotrophic lateral sclerosis in Japan, 1995-2001
    Kazushi Okamoto
    Department of Public Health, Aichi Prefectural College of Nursing and Health, Nagoya, Japan
    J Epidemiol 15:20-3. 2005
    ....
  25. doi Psychological stress in a Japanese population with systemic lupus erythematosus: finding from KYSS study
    Hiroki Takahashi
    First Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan
    Mod Rheumatol 24:448-52. 2014
    ..However, there is little information about the relationship between daily psychological stress and the risk of SLE in a Japanese population. We examined the association between SLE and daily psychological stress...
  26. ncbi Vegetable, fruit, and cereal intake and risk of idiopathic pulmonary fibrosis in Japan
    Yoshihiro Miyake
    Department of Public Health, Fukuoka University School of Medicine, 7 45 1 Nanakuma, Jonan ku, Fukuoka 814 0180, Japan
    Ann Nutr Metab 48:390-7. 2004
    ..We investigated the relationship between dietary intake of vegetables, fruit, cereals, antioxidants, and fiber and the risk of IPF in Japan...
  27. ncbi Pre-conceptional natural killer cell activity and percentage as predictors of biochemical pregnancy and spontaneous abortion with normal chromosome karyotype
    Hideto Yamada
    Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Am J Reprod Immunol 50:351-4. 2003
    ..The aim of the present study was to determine whether pre-conceptional natural killer (NK) cell activity and percentage are predictive of subsequent spontaneous abortion in women with recurrent spontaneous abortion (RSA)...
  28. ncbi Smoking, drinking, sleeping habits, and other lifestyle factors and the risk of systemic lupus erythematosus in Japanese females: findings from the KYSS study
    Masakazu Washio
    Sapporo Medical University School of Medicine, Sapporo, Japan
    Mod Rheumatol 16:143-50. 2006
    ..However, in Hokkaido, this association between smoking and SLE did not reach statistical significance after adjusting for alcohol drinking. The present study suggests that smoking may increase the risk of SLE among Japanese females...
  29. doi Antiphospholipid antibodies increase the risk of pregnancy-induced hypertension and adverse pregnancy outcomes
    Hideto Yamada
    Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Kita ku N15 W7, Sapporo 060 8638, Japan
    J Reprod Immunol 79:188-95. 2009
    ..7-66.7) or IgG aPE plus LA (22.2, 5.4-909) measurements predicted severe PIH with 30.8% sensitivity and 99.2% specificity. We conclude that aPL measurements during early pregnancy may be useful in predicting adverse pregnancy outcome...
  30. ncbi Maternal serum and amniotic fluid bisphenol A concentrations in the early second trimester
    Hideto Yamada
    Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Kita ku N15 W7, Sapporo 060 8638, Japan
    Reprod Toxicol 16:735-9. 2002
    ..80-5.62 ng/ml). In Group II, BPA concentrations in AF (0 ng/ml) were lower (P<0.01) than in MS (2.97 ng/ml). MS BPA concentrations in Group II were higher (P<0.01) than in Group I...
  31. doi Specific ultrasound findings associated with fetal chromosome abnormalities
    Shigeki Shimada
    Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, and Sapporo City General Hospital, Sapporo, Japan
    Congenit Anom (Kyoto) 49:61-5. 2009
    ..0, 1.7-14.4) and cardiovascular abnormality (3.3, 1.1-10.1) were significant variants associated with fetal chromosomal abnormalities. Information revealed in the present study constitutes a beneficial reference for genetic counseling...
  32. ncbi Visuospatial imagery is a fruitful strategy for the digit span backward task: a study with near-infrared optical tomography
    Y Hoshi
    Biophysics Group, Research Institute for Electronic Science, Hokkaido University, North Ward, North 12, West 6, Sapporo, Japan
    Brain Res Cogn Brain Res 9:339-42. 2000
    ..These results suggest that visuospatial imagery is a useful strategy for the DB task. Optical tomography described here is a new modality of neuropsychological studies...
  33. doi Low levels of plasma protein S, protein C and coagulation factor XII during early pregnancy and adverse pregnancy outcome
    Yasuhiko Ebina
    Prof Hideto Yamada, MD, PhD, Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, 7 5 1 Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan, Tel 81 78 382 6005, Fax 81 78 382 6019, E mail
    Thromb Haemost 114:65-9. 2015
    ..In conclusion, women with low levels of plasma PS activity and free PS during early pregnancy might have increased risks of PIH, severe PIH or pre-eclampsia. Women with low FXII level might have an increased risk of PD at <‚ÄČ34 GW...
  34. ncbi Cranial computed tomography associated with development of functional dependence in a community-based elderly population
    Eri Tsukishima
    Department of Public Health, Hokkaido University Graduate School of Medicine, Japan
    J Epidemiol 12:153-9. 2002
    ..To investigate whether changes at computed tomography (CT) imaging in the ageing brain are associated with future risks for functional dependence...
  35. ncbi HLA-DQB1 0602 allele is associated with splenomegaly in Japanese sarcoidosis
    H Sato
    Interstitial Lung Disease Unit, Royal Brompton Hospital and NHLI, Imperial College of Science, Technology and Medicine, London, UK
    J Intern Med 262:449-57. 2007
    ..In other diseases, HLA class II alleles can be markers for splenomegaly. We therefore set out to test the hypothesis that the primary DRB1 15-DQB1 0602 link in sarcoidosis would be to splenomegaly...
  36. ncbi Analysis of IL-18 bioactivity and IL-18 mRNA in three patients with adult T-cell leukaemia, acute mixed lineage leukaemia, and acute lymphocytic leukaemia accompanied with high serum IL-18 levels
    T Takubo
    Clinical Hematology and Clinical Diagnostics, Graduate School of Medicine, Osaka City University, Japan
    Haematologia (Budap) 31:231-5. 2001
    ..There was little serum IL-18 bioactivity in the three patients with ATL, AMLL and ALL, while IL-18 mRNA expression was detected in leukaemia cells of all three patients...
  37. ncbi [Health status and lifestyle issues of homeless people in Sapporo city, 2000]
    G Kobashi
    Department of Health for Senior Citizens, Hokkaido University Graduate School of Medicine
    Nippon Koshu Eisei Zasshi 48:785-93. 2001
    ..In addition, it is important to establish a more reliable registration system for these people in order to plan and provide a comprehensive social and health support network as needed...
  38. ncbi Effectiveness of washed platelet concentrate and red cell transfusions for a patient with anhaptoglobinemia with antihaptoglobin antibody
    S Nishiki
    Department of Clinical Hematology and Diagnostics, Osaka City University, Graduate School of Medicine, Japan
    Transfus Med 12:71-3. 2002
    ..No antibodies against human leucocyte antigen (HLA) or platelet-specific antigens were detected. Washed PC and washed red blood cells were effective in preventing the transfusion-related anaphylactoid reactions...
  39. ncbi E-cadherin expression in lymph nodes of three patients with non-Hodgkin's lymphoma
    T Takubo
    Clinical Hematology and Clinical Diagnostics, Graduate School of Medicine, Osaka City University, Japan
    Haematologia (Budap) 32:67-72. 2002
    ..Expression of E-cadherin may contribute to the morphological appearance of some malignant lymphoma, although no conclusion can be drawn based on such small number of patients analyzed...
  40. ncbi Clinical significance of serum E-selectin levels in patients with various haematologic malignancies
    T Takubo
    Haematologia (Budap) 32:97-100. 2002
  41. ncbi Serum sialyl Lewis(x) levels in patients with various haematologic malignancies
    T Takubo
    Clinical Hematology and Clinical Diagnostics, Graduate School of Medicine, Osaka City University, Japan
    Haematologia (Budap) 32:147-9. 2002
  42. ncbi Variations in the human CC chemokine eotaxin gene
    M Miyamasu
    Department of Allergy and Rheumatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Genes Immun 2:461-3. 2001
    ..Significant linkage disequilibrium was observed between positions -426 and -384, and also between -384 and +67. No significant association was observed between these variations and susceptibility to asthma...
  43. ncbi Lymph node metastasis and preoperative diagnosis of depth of invasion in early gastric cancer
    Y Seto
    Department of Gastrointestinal Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Gastric Cancer 4:34-8. 2001
    ..These metastases rarely extended beyond the first tier. CONCLUSION: N0 and M-cancers, m-cancers less than 4 cm in diameter, and sm-cancers no larger than 1 cm in diameter may be appropriate indications for limited surgery...
  44. ncbi Platelet recovery after eradication of Helicobacter pylori in patients with idiopathic thrombocytopenic purpura
    M Hino
    Department of Clinical Hematology and Clinical Diagnostics, Osaka City University, Graduate School of Medicine, 1 4 3, Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Ann Hematol 82:30-2. 2003
    ..On the other hand, eradication therapy did not affect platelet counts in patients with gastric ulcer. In conclusion, H. pylori eradication can be used for initial treatment with tolerable adverse effects in some ITP patients...
  45. doi Neuroferritinopathy in a Japanese family with a duplication in the ferritin light chain gene
    E Ohta
    Department of Neurology, Interdisciplinary Graduate School of Medicine and Engineering University of Yamanashi, 1110 Shimokatou Chuo city, Yamanashi, 409 3898, Japan
    Neurology 70:1493-4. 2008
  46. ncbi Electrocardiogram is very useful for predicting acute heart failure following myeloablative chemotherapy with hematopoietic stem cell transplantation rescue
    M Akahori
    Clinical Hematology, Graduate School of Medicine, Osaka City University, Japan
    Bone Marrow Transplant 31:585-90. 2003
    ..0-100). These results suggest that echocardiographic markers are less valuable predictors of post-transplant AHF, but that prolongation of the QTc, an ECG marker, before HSCT is strongly associated with onset of AHF after HSCT...
  47. ncbi Hypoxia induces expression and activation of AMPK in rat dental pulp cells
    Y Fukuyama
    Department of Endodontics, Tokyo Dental College, Chiba City, Japan
    J Dent Res 86:903-7. 2007
    ....
  48. ncbi Clinical and experimental features of MuSK antibody positive MG in Japan
    K Ohta
    Clinical Research Center, Utano National Hospital, Kyoto, Japan
    Eur J Neurol 14:1029-34. 2007
    ..Measurement of MuSK Ab titers aids in the diagnosis of MG and the monitoring of clinical courses after treatment...
  49. ncbi A survey on awareness and utilization of new asthma management guidelines in Japan
    S Makino
    Tokyo Allergic Disease Research Institute, Kihara Hospital, Tokyo, Japan
    J Asthma 40:701-8. 2003
    ..Furthermore, high reference and high expectancy also verified that physicians recognize the contents of the present guidelines as appropriate...
  50. pmc Sgs1 helicase activity is required for mitotic but apparently not for meiotic functions
    A Miyajima
    Division of Pharmacology, Biological Safety Research Center, National Institute of Health Sciences, Setagaya Ku, Tokyo 158 8501, Japan
    Mol Cell Biol 20:6399-409. 2000
    ....
  51. ncbi Mutations in the TRKA/NGF receptor gene in patients with congenital insensitivity to pain with anhidrosis
    Y Indo
    Department of Pediatrics, Kumamoto University School of Medicine, Japan
    Nat Genet 13:485-8. 1996
    ..These results also implicate genes encoding other TRK and neurotrophin family members as candidates for developmental defect(s) of the nervous system...
  52. ncbi Detection of minimal residual disease in acute leukemia by Tc-99m MIBI femoral marrow imaging
    S Wakasugi
    Department of Nuclear Medicine, Osaka Medical Center for Cancer and Cardiovascular Diseases, Japan
    Clin Nucl Med 26:325-30. 2001
    ..MIBI femoral marrow imaging may be a useful and simple method for monitoring levels of residual leukemic cells. Clearly visualized MIBI accumulation may be a marker for relapse...
  53. ncbi Growth factors, extracellular matrix components and cell adhesion molecules Warthin's tumor
    Y Nakamura
    Department of Pathology, St Mary's Hospital, Kurume-shi, Japan
    J Oral Pathol Med 30:290-5. 2001
    ..These various proteins may interact and regulate the proliferation and cell attachment of both epithelial and lymphoid components in this unique tumor...
  54. ncbi Virus-associated hemophagocytic syndrome due to rubella virus and varicella-zoster virus dual infection in patient with adult idiopathic thrombocytopenic purpura
    Y Takeoka
    Department of Clinical Hematology, Osaka City University Medical School, Japan
    Ann Hematol 80:361-4. 2001
    ..Her simultaneous rubella virus and VZV infection may have been related to the VAHS pathogenesis. She was treated with prednisolone and gamma globulin therapy and recovered completely...
  55. ncbi Stability of exploratory eye movements as a marker of schizophrenia--a WHO multi-center study. World Health Organization
    T Kojima
    Department of Neuropsychiatry, Nihon University School of Medicine, Oyaguchi Kamimachi 30-1, Itabashi-ku, Tokyo 173-8610, Japan
    Schizophr Res 52:203-13. 2001
    ..Furthermore, it is indicative of the stable, significant difference that exists between subjects with and without schizophrenia. The results of discriminant analysis confirm the previously reported validity of discriminant function...