Genomes and Genes
Affiliation: Institute for Developmental Research
- DDX6 post-transcriptionally down-regulates miR-143/145 expression through host gene NCR143/145 in cancer cellsAkio Iio
United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, Yanagido, Gifu, Gifu 501 1193, Japan Department of Embryology, Institute for Developmental Research, Aichi Human Service Center, 713 8 Kamiya cho, Kasugai, Aichi 480 0392, Japan Electronic address
Biochim Biophys Acta 1829:1102-10. 2013..These data demonstrate that DDX6 contributed to the control of NCR143/145 RNA stability in P-bodies and post-transcriptionally regulated miR-143/145 expression in cancer cells. ..
- Molecular hydrogen attenuates fatty acid uptake and lipid accumulation through downregulating CD36 expression in HepG2 cellsAkio Iio
Research Team for Mechanism of Aging, Tokyo Metropolitan Institute of Gerontology, 35 2 Sakae cho, Itabashi, Tokyo, 173 0015, Japan
Med Gas Res 3:6. 2013....
- Microvesicle-mediated RNA molecule delivery system using monocytes/macrophagesYukihiro Akao
United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, Gifu, Japan
Mol Ther 19:395-9. 2011..These data suggest that some of the transfected miR-143BPs were secreted from THP-1 macrophages as MV-RNAs both in vitro and in vivo...
- Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cellsYukihiro Akao
Gifu University, Yanagido, Japan
Cancer Lett 300:197-204. 2011..These findings suggest that miR-34a targeting the Sirt1 and E2F3 genes could negatively regulate, at least in part, the resistance to 5-FU in human colorectal cancer DLD-1 cells...