Kazue Aoyama

Summary

Affiliation: Kagoshima University
Country: Japan

Publications

  1. pmc Characterization of a Novel d-Glycero-d-talo-oct-2-ulosonic acid-substituted Lipid A Moiety in the Lipopolysaccharide Produced by the Acetic Acid Bacterium Acetobacter pasteurianus NBRC 3283
    Masahito Hashimoto
    From the Department of Chemistry, Biotechnology, and Chemical Engineering, Kagoshima University, Kagoshima 890 0065, Japan
    J Biol Chem 291:21184-21194. 2016
  2. doi request reprint Separation and characterization of the immunostimulatory components in unpolished rice black vinegar (kurozu)
    Masahito Hashimoto
    Department of Chemistry, Biotechnology, and Chemical Engineering, Kagoshima University, Korimoto 1 21 40, Kagoshima 890 0065, Japan Electronic address
    J Biosci Bioeng 116:688-96. 2013
  3. doi request reprint Identification of a TLR2-stimulating lipoprotein in Bacteroides fragilis JCM 11019 (NCTC 9343)
    Masahito Hashimoto
    Department of Chemistry, Biotechnology, and Chemical Engineering, Kagoshima University, Kagoshima, Japan
    Innate Immun 19:132-9. 2013
  4. pmc Characterization of nitric oxide-inducing lipid A derived from Mesorhizobium loti lipopolysaccharide
    Masahito Hashimoto
    Department of Chemistry, Biotechnology, and Chemical Engineering, Kagoshima University, Korimoto 1 21 40, Kagoshima 890 0065, Japan
    Microbes Environ 27:490-6. 2012
  5. ncbi request reprint Lipoprotein is a predominant Toll-like receptor 2 ligand in Staphylococcus aureus cell wall components
    Masahito Hashimoto
    Department of Nanostructure and Advanced Materials, Kagoshima University, Korimoto 1 21 40, Kagoshima 890 0065, Japan
    Int Immunol 18:355-62. 2006
  6. ncbi request reprint Not lipoteichoic acid but lipoproteins appear to be the dominant immunobiologically active compounds in Staphylococcus aureus
    Masahito Hashimoto
    Department of Nanostructure and Advanced Materials, Kagoshima University, Kagoshima, Japan
    J Immunol 177:3162-9. 2006
  7. pmc Evidence of immunostimulating lipoprotein existing in the natural lipoteichoic acid fraction
    Masahito Hashimoto
    Department of Nanostructure and Advanced Materials, Kagoshima University, Korimoto 1 21 40, Kagoshima 890 0065, Japan
    Infect Immun 75:1926-32. 2007
  8. ncbi request reprint Possible involvement of put A gene in Helicobacter pylori colonization in the stomach and motility
    Kazuhiko Nakajima
    Department of Infection Control and Prevention, Hyogo College of Medicine, Hyogo, Japan
    Biomed Res 29:9-18. 2008

Collaborators

  • Yukari Fujimoto
  • Toshiki Uchiumi
  • Ken ichi Kucho
  • Nobutaka Eiraku
  • Shoichi Kusumoto
  • Friedrich Götz
  • T Kirikae
  • Masahito Hashimoto
  • Yasuo Suda
  • Koichi Fukase
  • Maiko Furuyashiki
  • Kazuki Tawaratsumida
  • Mami Ozono
  • Kazuhiko Nakajima
  • Toshihide Tamura
  • Hiroyuki Kariya
  • Risako Baba
  • Shuhei Hashiguchi
  • Tsuyoshi Ikeda
  • Kyoko Obara
  • Haruka Eguchi
  • Hiroshi Shigehisa
  • Maki Nagata
  • Youhei Tanishita
  • Mikiko Abe
  • Ei ichi Murakami
  • Yoshihiro Fukuda
  • Kumiko Nagata
  • Tomoko Mizote
  • Yoko Nagata
  • Sakiko Inatsu
  • Hirofumi Morioka
  • Katsuhiro Takashige
  • Fumiko Kirikae
  • Ryoko Kaseya
  • Mai Akimaru
  • Toshiomi Okuno
  • Yuka Fukada
  • Yoichiro Moriya
  • Ai Kiyohara
  • Fumiko Krikae

Detail Information

Publications8

  1. pmc Characterization of a Novel d-Glycero-d-talo-oct-2-ulosonic acid-substituted Lipid A Moiety in the Lipopolysaccharide Produced by the Acetic Acid Bacterium Acetobacter pasteurianus NBRC 3283
    Masahito Hashimoto
    From the Department of Chemistry, Biotechnology, and Chemical Engineering, Kagoshima University, Kagoshima 890 0065, Japan
    J Biol Chem 291:21184-21194. 2016
    ..These results suggest that the structurally atypical A. pasteurianus lipid A found in this study remains stable and, hence, retains its immunostimulatory activity during acetic acid fermentation...
  2. doi request reprint Separation and characterization of the immunostimulatory components in unpolished rice black vinegar (kurozu)
    Masahito Hashimoto
    Department of Chemistry, Biotechnology, and Chemical Engineering, Kagoshima University, Korimoto 1 21 40, Kagoshima 890 0065, Japan Electronic address
    J Biosci Bioeng 116:688-96. 2013
    ..These components might be responsible for the beneficial health effects of kurozu...
  3. doi request reprint Identification of a TLR2-stimulating lipoprotein in Bacteroides fragilis JCM 11019 (NCTC 9343)
    Masahito Hashimoto
    Department of Chemistry, Biotechnology, and Chemical Engineering, Kagoshima University, Kagoshima, Japan
    Innate Immun 19:132-9. 2013
    ..These results showed that the lipoprotein acts as a TLR2-stimulating component in B. fragilis...
  4. pmc Characterization of nitric oxide-inducing lipid A derived from Mesorhizobium loti lipopolysaccharide
    Masahito Hashimoto
    Department of Chemistry, Biotechnology, and Chemical Engineering, Kagoshima University, Korimoto 1 21 40, Kagoshima 890 0065, Japan
    Microbes Environ 27:490-6. 2012
    ..The partial hydrolysis of lipid A appeared to reduce its NO-inducing activity. These results suggest that L. japonicus root cells recognize the lipid A structure as a means of controlling NO production...
  5. ncbi request reprint Lipoprotein is a predominant Toll-like receptor 2 ligand in Staphylococcus aureus cell wall components
    Masahito Hashimoto
    Department of Nanostructure and Advanced Materials, Kagoshima University, Korimoto 1 21 40, Kagoshima 890 0065, Japan
    Int Immunol 18:355-62. 2006
    ..Further, most of the activity was abrogated by lipoprotein lipase digestion. These results suggested that lipoproteins are predominant TLR2 ligands in S. aureus cell wall components...
  6. ncbi request reprint Not lipoteichoic acid but lipoproteins appear to be the dominant immunobiologically active compounds in Staphylococcus aureus
    Masahito Hashimoto
    Department of Nanostructure and Advanced Materials, Kagoshima University, Kagoshima, Japan
    J Immunol 177:3162-9. 2006
    ..Further, alanylation of LTA molecule showed no effect in immunobiological activity. These results showed that not LTA molecule but lipoproteins are dominant immunobiologically active TLR2 ligand in S. aureus...
  7. pmc Evidence of immunostimulating lipoprotein existing in the natural lipoteichoic acid fraction
    Masahito Hashimoto
    Department of Nanostructure and Advanced Materials, Kagoshima University, Korimoto 1 21 40, Kagoshima 890 0065, Japan
    Infect Immun 75:1926-32. 2007
    ..These results suggest that MAbEh1 neutralizes the activity of lipoprotein-like compounds which is responsible for the activity of the LTA fraction of E. hirae and S. aureus...
  8. ncbi request reprint Possible involvement of put A gene in Helicobacter pylori colonization in the stomach and motility
    Kazuhiko Nakajima
    Department of Infection Control and Prevention, Hyogo College of Medicine, Hyogo, Japan
    Biomed Res 29:9-18. 2008
    ..DeltaputA had lost its ability to colonize the stomach of nude mice, an ability possessed by the wild-type. These findings indicate that put A may play an important role in H. pylori colonization on the gastric mucus layer...