Takeshi Teramura

Summary

Affiliation: Kinki University
Country: Japan

Publications

  1. doi request reprint Induction of mesenchymal progenitor cells with chondrogenic property from mouse-induced pluripotent stem cells
    Takeshi Teramura
    Institute of Advanced Clinical Medicine, Kinki University School of Medicine, Osaka, Japan
    Cell Reprogram 12:249-61. 2010
  2. doi request reprint Reduced oxygen concentration enhances conversion of embryonic stem cells to epiblast stem cells
    Toshiyuki Takehara
    Division of Cell Biology for Regenerative Medicine, Institute of Advanced Clinical Medicine, Kinki University Faculty of Medicine, Osaka, Japan
    Stem Cells Dev 21:1239-49. 2012
  3. pmc Reactive oxygen species induce Cox-2 expression via TAK1 activation in synovial fibroblast cells
    Yuta Onodera
    Division of Cell Biology for Regenerative Medicine, Institute of Advanced Clinical Medicine, Kindai University Faculty of Medicine, Osaka, Japan
    FEBS Open Bio 5:492-501. 2015
  4. doi request reprint Induction of functional mesenchymal stem cells from rabbit embryonic stem cells by exposure to severe hypoxic conditions
    Takeshi Teramura
    Institute of Advanced Clinical Medicine, Kinki University Faculty of Medicine, Osaka 5898511, Japan
    Cell Transplant 22:309-29. 2013
  5. pmc Generation of embryonic stem cell lines from immature rabbit ovarian follicles
    Takeshi Teramura
    Division of Cell Biology for Regenerative Medicine, Institute of Advanced Clinical Medicine, Kinki University Faculty of Medicine, Osaka, Japan
    Stem Cells Dev 22:928-38. 2013
  6. doi request reprint Mechanical stimulation of cyclic tensile strain induces reduction of pluripotent related gene expressions via activation of Rho/ROCK and subsequent decreasing of AKT phosphorylation in human induced pluripotent stem cells
    Takeshi Teramura
    Institute of Advanced Clinical Medicine, Kinki University, Faculty of Medicine, Osaka, Japan
    Biochem Biophys Res Commun 417:836-41. 2012
  7. pmc Isolation and characterization of side population stem cells in articular synovial tissue
    Takeshi Teramura
    Institute of Advanced Clinical Medicine, Kinki University School of Medicine, Ohno Higashi, Osaka Sayama, Osaka 589 8511, Japan
    BMC Musculoskelet Disord 9:86. 2008
  8. ncbi request reprint Mouse androgenetic embryonic stem cells differentiated to multiple cell lineages in three embryonic germ layers in vitro
    Takeshi Teramura
    Department of Obstetrics and Gynecology, Graduate School of Medicine, Mie University
    J Reprod Dev 55:283-92. 2009
  9. ncbi request reprint Isolation and culture of rabbit primordial germ cells
    Ryo Kakegawa
    Graduate School of Biology Oriented Science and Technology, Kinki University, Wakayama, Japan
    J Reprod Dev 54:352-7. 2008
  10. doi request reprint Potential existence of stem cells with multiple differentiation abilities to three different germ lineages in mouse neurospheres
    Toshiyuki Takehara
    Graduate School of Biology Oriented Science and Technology, Kinki University, Nishimitani, Kinokawa, Wakayama, Japan
    Stem Cells Dev 18:1433-40. 2009

Collaborators

  • Naoto Fukunaga
  • Akira Iritani
  • Hideki Murakami
  • Satoshi Kishigami
  • Shu Hashimoto
  • Nobuo Nagai
  • Toshiyuki Takehara
  • Yuta Onodera
  • Kanji Fukuda
  • Chiaki Hamanishi
  • Yoshihiko Hosoi
  • Masao Akagi
  • Norimasa Sagawa
  • Ryo Kakegawa
  • Kazuya Matsumoto
  • Kazuhiro Saeki
  • Kohei Kitada
  • Ichiro Tsukamoto
  • Koichi Nakagawa
  • Yoshihisa Miki
  • Tasuku Mitani
  • Masayuki Anzai
  • Satoshi Zushi
  • Hiroyuki Kanaya
  • Kayo Yoshida
  • Shoji Fukushima
  • Masayasu Koyama
  • Akane Kizu
  • Takashi Morita
  • John Frampton
  • Hideki Wanibuchi
  • Masami Hayashi
  • Kanae Shigi
  • Daisuke Tachibana
  • Kazuhiro Ohtani
  • Shinji Inoue
  • Madoka Ozawa
  • Toshiki Matsuoka
  • Takashi Tomiyama
  • Tatsuya Sawamura
  • Hideki Kishimoto
  • Makoto Takenoshita
  • Yoshiharu Morimoto

Detail Information

Publications23

  1. doi request reprint Induction of mesenchymal progenitor cells with chondrogenic property from mouse-induced pluripotent stem cells
    Takeshi Teramura
    Institute of Advanced Clinical Medicine, Kinki University School of Medicine, Osaka, Japan
    Cell Reprogram 12:249-61. 2010
    ..The present study demonstrates the property of iPS cells as an alternative candidate for treatment of articular disorders, and suggests an effective approach for preparing chondrocyte from iPS cells...
  2. doi request reprint Reduced oxygen concentration enhances conversion of embryonic stem cells to epiblast stem cells
    Toshiyuki Takehara
    Division of Cell Biology for Regenerative Medicine, Institute of Advanced Clinical Medicine, Kinki University Faculty of Medicine, Osaka, Japan
    Stem Cells Dev 21:1239-49. 2012
    ..Our data provide evidence that oxygen concentration is an important factor for establishment of the EpiSC-specific state...
  3. pmc Reactive oxygen species induce Cox-2 expression via TAK1 activation in synovial fibroblast cells
    Yuta Onodera
    Division of Cell Biology for Regenerative Medicine, Institute of Advanced Clinical Medicine, Kindai University Faculty of Medicine, Osaka, Japan
    FEBS Open Bio 5:492-501. 2015
    ..From these results, we conclude that oxidative stress is an important factor for generation of Cox-2 in synovial fibroblasts and thus its neutralization may be an effective strategy in palliative therapy for chronic joint diseases...
  4. doi request reprint Induction of functional mesenchymal stem cells from rabbit embryonic stem cells by exposure to severe hypoxic conditions
    Takeshi Teramura
    Institute of Advanced Clinical Medicine, Kinki University Faculty of Medicine, Osaka 5898511, Japan
    Cell Transplant 22:309-29. 2013
    ..These results support the notion that exposing ESCs to severe hypoxic conditions during differentiation can be used as a strategy for the preparation of functional MSCs from ESCs...
  5. pmc Generation of embryonic stem cell lines from immature rabbit ovarian follicles
    Takeshi Teramura
    Division of Cell Biology for Regenerative Medicine, Institute of Advanced Clinical Medicine, Kinki University Faculty of Medicine, Osaka, Japan
    Stem Cells Dev 22:928-38. 2013
    ..Moreover, the use of rabbit oocytes as a cell source provides an experimental system that closely matches human reproductive and stem cell physiology...
  6. doi request reprint Mechanical stimulation of cyclic tensile strain induces reduction of pluripotent related gene expressions via activation of Rho/ROCK and subsequent decreasing of AKT phosphorylation in human induced pluripotent stem cells
    Takeshi Teramura
    Institute of Advanced Clinical Medicine, Kinki University, Faculty of Medicine, Osaka, Japan
    Biochem Biophys Res Commun 417:836-41. 2012
    ..These results clearly suggested that the Rho/ROCK is a potent primary effector of mechanical stress in the pluripotent stem cells and it participates to pluripotency-related signaling cascades as an upper stream regulator...
  7. pmc Isolation and characterization of side population stem cells in articular synovial tissue
    Takeshi Teramura
    Institute of Advanced Clinical Medicine, Kinki University School of Medicine, Ohno Higashi, Osaka Sayama, Osaka 589 8511, Japan
    BMC Musculoskelet Disord 9:86. 2008
    ..Although SP cells from synovial tissue were expected to be an excellent source for this tissue engineering, their precise character in the synovial tissue has not been determined...
  8. ncbi request reprint Mouse androgenetic embryonic stem cells differentiated to multiple cell lineages in three embryonic germ layers in vitro
    Takeshi Teramura
    Department of Obstetrics and Gynecology, Graduate School of Medicine, Mie University
    J Reprod Dev 55:283-92. 2009
    ....
  9. ncbi request reprint Isolation and culture of rabbit primordial germ cells
    Ryo Kakegawa
    Graduate School of Biology Oriented Science and Technology, Kinki University, Wakayama, Japan
    J Reprod Dev 54:352-7. 2008
    ..From these characteristics and further characterization of the germ stem cell markers Vasa, SCP-1 and SCP-3, we suggested that these were hybrid cells with characteristics somewhere between PGC and EG cells...
  10. doi request reprint Potential existence of stem cells with multiple differentiation abilities to three different germ lineages in mouse neurospheres
    Toshiyuki Takehara
    Graduate School of Biology Oriented Science and Technology, Kinki University, Nishimitani, Kinokawa, Wakayama, Japan
    Stem Cells Dev 18:1433-40. 2009
    ..The results of the present study partly provide further evidence for multiple differentiation properties of NSCs and suggest common characteristics between NSCs and other pluripotent stem cells...
  11. doi request reprint Differentiation diversity of mouse parthenogenetic embryonic stem cells in chimeric mice
    Yuta Onodera
    Institute of Advanced Clinical Medicine, Kinki University School of Medicine, Osaka Sayama, Osaka, Japan
    Theriogenology 74:135-45. 2010
    ..We concluded that PgESCs contributed to various internal organs in vivo, and that they were also stably maintained in adult animals...
  12. doi request reprint Cyclic compression-induced p38 activation and subsequent MMP13 expression requires Rho/ROCK activity in bovine cartilage explants
    Koichi Nakagawa
    Department of Orthopaedic Surgery, Kinki University Faculty of Medicine, Osaka, Japan
    Inflamm Res 61:1093-100. 2012
    ..However, precise pathway inducing p38 activation has not been elucidated. We hypothesized here that the small GTPase Rho and its effector ROCK might function in upper part of the mechanical stress-induced matrix degeneration pathway...
  13. doi request reprint Hyaluronan reversed proteoglycan synthesis inhibited by mechanical stress: possible involvement of antioxidant effect
    Yoshihisa Miki
    Department of Orthopaedic Surgery, Kinki University School of Medicine, Osaka, Japan
    Inflamm Res 59:471-7. 2010
    ..Abnormal mechanical stress loaded on the cartilage leads to the osteoarthritis (OA). Although intraarticular hyaluronan (HA) injection is an effective treatment for OA, the underlying mechanism has not been made clear...
  14. doi request reprint Leukemia inhibitory factor (LIF) enhances germ cell differentiation from primate embryonic stem cells
    Naoto Fukunaga
    Department of Biology Oriented Science and Technology, Kinki University, Osaka, Japan
    Cell Reprogram 12:369-76. 2010
    ....
  15. pmc Rho-associated kinase inhibitor Y-27632 promotes survival of cynomolgus monkey embryonic stem cells
    Toshiyuki Takehara
    Graduate School of Biology Oriented Science and Technology, Kinki University, Nishimitani, Kinokawa, Wakayama 649 6493, Japan
    Mol Hum Reprod 14:627-34. 2008
    ....
  16. ncbi request reprint Primate embryonic stem cells proceed to early gametogenesis in vitro
    Takeshi Teramura
    Department of Obstetrics and Gynecology, Graduate School of Medicine, Mie University, Mie, Japan
    Cloning Stem Cells 9:144-56. 2007
    ....
  17. ncbi request reprint A mouse and embryonic stem cell derived from a single embryo
    Takeshi Teramura
    Department of Obstetrics and Gynecology, Graduate School of Medicine, Mie University, Tsu, Mie, Japan
    Cloning Stem Cells 9:485-94. 2007
    ..These results show that each blastomere at two-cell stage possesses pluripotency and separated blastomeres maintain viability to develop to a pup or pluripotent ESC...
  18. ncbi request reprint Mitochondrial dysfunction of in vitro grown rabbit oocytes results in preimplantation embryo arrest after activation
    Hiroyuki Kanaya
    Department of Biology Oriented Science and Technology, Division of Genetic Engineering, Kinki University, Japan
    J Reprod Dev 53:631-7. 2007
    ..Taken together, these results indicate that the low developmental competence of IVG oocytes is caused by a cytoplasm deficiency due to low mitochondrial activity...
  19. pmc Cdh2 stabilizes FGFR1 and contributes to primed-state pluripotency in mouse epiblast stem cells
    Toshiyuki Takehara
    Division of Cell Biology for Regenerative Medicine, Institute of Advanced Clinical Medicine, Kindai University Faculty of Medicine, 377 2 Ohnohigashi, Osaka Sayama, Osaka, Japan 5898511
    Sci Rep 5:14722. 2015
    ..Thus, Cdh2 contributes to the establishment and maintenance of FGF signaling-dependent self-renewal in mEpiSCs through stabilization of FGFR1. ..
  20. doi request reprint Induction of bovine articular chondrocyte senescence with oxidized low-density lipoprotein through lectin-like oxidized low-density lipoprotein receptor 1
    Satoshi Zushi
    Kinki University School of Medicine, Osaka Sayama City, Osaka, Japan
    Arthritis Rheum 60:3007-16. 2009
    ..The purpose of this study was to determine whether ox-LDL induces chondrocyte senescence through binding to lectin-like ox-LDL receptor 1 (LOX-1)...
  21. doi request reprint Systemic transplantation of embryonic stem cells accelerates brain lesion decrease and angiogenesis
    Nobuo Nagai
    Department of Physiology, Kinki University School of Medicine, Osaka, Japan
    Neuroreport 21:575-9. 2010
    ..These findings suggested that embryonic stem cell transplantation reduced the brain lesion through the acceleration of angiogenesis by endogenous endothelial cells...
  22. pmc Activating types 1 and 2 angiotensin II receptors modulate the hypertrophic differentiation of chondrocytes
    Ichiro Tsukamoto
    Department of Orthopaedic Surgery, Faculty of Medicine, Kinki University, 377 2 Ohno Higashi, Osaka Sayama City, Osaka 589 8511, Japan
    FEBS Open Bio 3:279-84. 2013
    ..Activation of AT1R suppressed and activation of AT2R enhanced the expression of markers of hypertrophic differentiation, including type X collagen, matrix metalloproteinase 13 and runt-related transcription factor 2...
  23. doi request reprint Gene-modified embryonic stem cell test to characterize chemical risks
    Kohei Kitada
    Department of Obstetrics and Gynecology, Osaka City University, Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka, 545 8585, Japan
    Environ Sci Pollut Res Int 22:18252-9. 2015
    ..Thus, ES test system using gene-modified ES cells may be used to categorize chemicals by detecting their characteristic effects on apoptosis, genotoxic potentials as well as general cytotoxicity. ..